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Plasma-Doped Si Nanosheets for Transistor and <i>p-n</i> Junction Application
Lee, Jaejun,Kwon, Juyoung,Seo, Dongjea,Na, Jukwan,Park, Sangwon,Lee, Hyo-Jung,Lee, Seung-Woo,Lee, Ki-Young,Park, Tae-Eon,Choi, Heon-Jin American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.45
<P>Since the discovery of graphene, layered transition metal dichalcogenides (TMDs) have been considered promising materials for applications in various fields because of their fascinating structural features and physical properties. Doping in semiconducting TMDs is essential for their practical application. In this regard, two-dimensional (2D) Si materials have emerged as a key component of 2D electronic, optics, sensing, and spintronic devices because of their complementary metal-oxide-semiconductor (CMOS) compatibility, high-quality oxide formation, moderated bandgap, and well-established doping techniques. Here, we report the tuning of the electronic properties of Si nanosheets (NSs) using a plasma-doping technique. Using this doping process, we fabricated <I>p</I>-<I>n</I> homojunction diodes and transistors with Si NSs. The estimated high ON/OFF ratio of ∼10<SUP>6</SUP> and field-effect hole mobility of 329 cm<SUP>2</SUP> V<SUP>-1</SUP> s<SUP>-1</SUP> suggest a high crystal quality of the Si NSs. We also demonstrate vertically stacked heterostructured <I>p</I>-<I>n</I> junction diodes with MoS<SUB>2</SUB>, which exhibit rectifying properties and excellent light response.</P> [FIG OMISSION]</BR>
( Jaejun Lee ),( Pil Soo Sung ),( Hyun Yang ),( Soon Kyu Lee ),( Sun Hong Yoo ),( Hae Lim Lee ),( Hee Yeon Kim ),( Jung-hyun Kwon ),( Hee Chul Nam ),( Sung Won Lee ),( Jeong Won Jang ),( Chang Wook Ki 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: In unresectable hepatocellular carcinoma (HCC), patients who are refractory to transarterial chemoembolization (TACE) or hepatic arterial infusion chemotherapy (HAIC) have been considered suitable for multikinase inhibitor treatment, and sorafenib has traditionally been used as a salvage treatment option. Recently, lenvatinib was demonstrated to be non-inferior to sorafenib in a phase 3 randomized controlled trial. In this study, we aimed to investigate the efficacy and safety of lenvatinib as a salvage treatment for HCC after transarterial treatment. Methods: Between January 2019 and March 2020, all patients with confirmed intermediate-to-advanced HCC who were administered lenvatinib treatment after transarterial treatment in five Korean centers were retrospectively analyzed. We used overall survival (OS), progression free survival (PFS), objective response rate (ORR) and disease control rate (DCR) to evaluate efficacy of the treatment. Clinical parameters and outcomes after the introduction of lenvatinib were assessed. Results: We enrolled 38 unresectable HCC patients treated with lenvatinib after transarterial treatment. At the time of treatment initiation, 6 and 32 patients were classified as BCLC stage B and C, respectively. For the liver reserve, patients were classified as Child-Pugh class A (30 patients) or B (8 patients). Previous treatment included TACE for 35 patients, HAIC for 10 patients, and both TACE and HAIC for 7 patients. The median OS and PFS was 5.9 months (range, 0.7-13.2 months) and 3.9 months (range, 0.1-9.6 months), respectively. Sixteen among 38 patients were administered a 12-mg daily dose and 22 were administered an 8-mg daily dose. During the treatment, 10 of 38 (26.3%) patients had hand-foot syndrome (HFS); only 3 patients had grade 3 toxicity HFS. Among the patients, 6 (15.8%) had proteinuria and only one patient suffered grade 2 proteinuria while others had grade 1. In a best response evaluation, 5 patients exhibited a partial response (13.2%) and 12 patients had achieved stable disease (31.6%) according to the mRECIST criteria. Patients in the disease-controlled state (CR+PR+SD) showed superior OS (P=0.006) and PFS (P=0.003) to those with PD. Tumor size less than 5 cm was also associated with longer PFS (P=0.045). There was no statistically significant difference between OS and the number of prior transarterial treatments. Conclusions: Lenvatinib treatment is safe and efficacious after the failure of transarterial treatments in unresectable HCC. Change of treatment modality from loco-regional treatment to lenvatinib before the deterioration of liver function may achieve better survival outcomes in advanced HCC.
무선 센서 네트워크를 이용한 농업 환경 모니터링 시스템 구현
이정민(Jeongmin Lee),한재준(Jaejun Han),이은애(Eunae Lee),이홍준(Hongjun Lee),김동식(Dong Sik Kim),정범진(Beom Jin Chung),손성용(Sung-Yong Son),구이란(Iran Koo),이형재(Hyung Jae Lee) 대한전자공학회 2015 대한전자공학회 학술대회 Vol.2015 No.11
In this paper, we developed a wireless sensor network system to monitor the temperature and humidity of the agriculture environment. In order to construct a low-cost and low-complexity system, a narrow-bandwidth communication based on 424MHz frequency band is considered while achieving reliable wireless links. The developed system is implemented in a farm for maesil, which is sort of plum. For a slope farm environment, the system can successfully gather the measured data.
Soon Kyu Lee,Sung Won Lee,Hae Lim Lee,Hee Yeon Kim,Chang Wook Kim,Do Seon Song,U Im Chang,Jin Mo Yang,Sun Hong Yoo,Jung Hyun Kwon,Soon Woo Nam,Seok-Hwan Kim,Myeong Jun Song,Jaejun Lee,Hyun Yang,Si Hyu 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.6
Background/Aims : To evaluate the efficacy and safety of ledipasvir/sofosbuvir (LDV/SOF) therapy in hepatitis C virus (HCV)-infected Korean patients in a real clinical setting. Methods: A total of 273 patients who received LDV/SOF therapy between May 2016 and February 2021 were consecutively enrolled and analyzed. A per-protocol analysis was performed to evaluate the virologic response. Results: Seventy-five percent were infected with genotype 1, and 25% were infected with genotype 2. A hundred eightyone (66.3%) patients had chronic hepatitis, 74 (27.1%) had compensated cirrhosis, eight (2.9%) had decompensated cirrhosis, and 10 (3.7%) had undergone liver transplantation. Undetectable HCV RNA at week 4 was achieved in 90.2% (231/256) of patients, 99.2% (250/252) achieved the end of treatment response, and 98.1% (202/206) achieved sustained virologic response at 12 weeks post-treatment (SVR12). According to liver function, the SVR12 rates were 99.3% (135/136) in chronic hepatitis, 96.4% (53/55) in compensated cirrhosis, and 100% (6/6) in decompensated cirrhosis. The SVR12 rates according to the genotype were 98.2% (167/170) for genotype 1 and 97.2% (35/36) for genotype 2. An 8-week LDV/SOF treatment in treatment-naïve chronic hepatitis patients with HCV RNA < 6,000,000 IU/mL at baseline resulted in 100% (23/23) SVR12 rates. Overall, LDV/SOF was tolerated well, with a 0.7% (2/273) discontinuation rate due to adverse events that were unrelated to LDV/SOF. Conclusions: LDV/SOF is effective and safe for treating HCV-infected Korean patients with high SVR12 rates.
Multi-Slot Main Memory System for Post DDR3
Jaejun Lee,Sungho Lee,Sangwook Nam IEEE 2010 IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS PART 2 E Vol.57 No.5
<P>This brief introduces a suitable architecture for a high-data rate and high-density system using bidirectional single-ended signaling. For chip-to-chip interconnections requiring high speed and high density for the main memory system, an SSTL-II-based structure was previously used. However, this structure is no longer applicable for higher speeds at higher densities. By using an optimum reflection coefficient at the junction of a branch, a multislot system acts in the same way as a point-to point system. This architecture significantly improves the signal integrity. The simulated jitter and eye openings, including transmission line loss, were improved by 53.4% for write operation and 65.1% for read operations at 3.2 Gbps under heavy loading conditions. The peak-to-peak time jitters of 67.1 and 72.0 ps were measured at 3.3 Gbps.</P>
Determination of the optimal number of coverages for the rolling of chip seals
Lee, Jaejun,Kim, Y. Richard Canadian Science Publishing 2010 Canadian journal of civil engineering. Revue canad Vol.37 No.1
<P> This paper presents a method to determine the optimal protocol for rolling chip seals based on aggregate retention performance and aggregate embedment depth. To evaluate performance, the flip-over test (FOT), the Vialit test, the modified sand circle test, and the third-scale model mobile loading simulator (MMLS3) were employed. Two chip seal types (single and double) and three numbers of coverages (1, 3, and 5) were used as parameters to determine an optimal number of coverages. It was found from the aggregate retention test results and measured aggregate embedment depths that three coverages is the optimum number of coverages and the extra time needed for the two additional coverages cannot be justified. </P>
A Financing Model to Solve Financial Barriers for Implementing Green Building Projects
Lee, Sanghyo,Lee, Baekrae,Kim, Juhyung,Kim, Jaejun Scientific World, Inc 2013 The Scientific World Journal Vol.2013 No.-
<P> Along with the growing interest in greenhouse gas reduction, the effect of greenhouse gas energy reduction from implementing green buildings is gaining attention. The government of the Republic of Korea has set green growth as its paradigm for national development, and there is a growing interest in energy saving for green buildings. However, green buildings may have financial barriers that have high initial construction costs and uncertainties about future project value. Under the circumstances, governmental support to attract private funding is necessary to implement green building projects. The objective of this study is to suggest a financing model for facilitating green building projects with a governmental guarantee based on Certified Emission Reduction (CER). In this model, the government provides a guarantee for the increased costs of a green building project in return for CER. And this study presents the validation of the model as well as feasibility for implementing green building project. In addition, the suggested model assumed governmental guarantees for the increased cost, but private guarantees seem to be feasible as well because of the promising value of the guarantee from CER. To do this, certification of Clean Development Mechanisms (CDMs) for green buildings must be obtained. </P>