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ProTaper의 세가지 사용방식에 따른 성형능역 비교
김소연,박정길,허복,김현철 大韓齒科保存學會 2005 Restorative Dentistry & Endodontics Vol.30 No.1
이 연구의 목적은 만곡이 삼한 근관에서 ProTaper(R)를 수동으로 사용하는 방법, 엔진 구동으로 사용하는 방법, 그리고, 치관부는 엔진 구동으로 치근단부는 수동으로 사용하는 세 가지 방법의 근관 성형 능력을 비교하기 위한 것이다. 근관 길이가 170mm이고 근관 입구에서 10mm 떨어진 부위에서 만곡이 시작되며 평균 40도의 단일 만곡을 가지는 투명한 레진 블락 30개를 사용하였다. 각 군당 10개의 레진 블락을 사용하였으며, 수동형 ProTaper(R)로 전체근관을 성형한 군형 M군, 엔진 구동형 ProTaper(R)로 전체근관을 성형한 군을 R군, 근단부는 수동형 ProTaper(R)를, 치관부는 엔진 구동형 ProTaper(R)를 사용하여 성형한 군을 H군으로 하였다. 각각의 블락을 성형하고 각 군별 근관 성형시간을 기록하였다. 근관 성형전과 후의 이미지를 중첩하여 근단공으로부터의 수직 이동 거리 1, 2, 3, 4, 5 그리고 6 mm 위치에서 수평선을 긋고 총 근관폭경, 근관 만곡 내외측 삭제량, 근관의 변위, 중심 이동률을 평가하여 다음과 같은 결론을 얻었다. 1. 근관 성형시간은 R군, H군, M군 순으로 짧았고, 세 군 사이에는 유의한 차이가 있었다(p < 0.05). 2. R군이 전체적으로 삭제량이 많은 경향을 보였으나, 1, 3 mm를 제외하고는 차이가 없었다(p > 0.05). 3. 만곡내측 삭제량에 있어서는 1 mm 지점에서는 R군이, 6 mm 지점에서는 H군이 컸지만 (p < 0.05), 나머지 지점에서는 차이가 없었다. 만곡외측 삭제량은 1 mm 지점에서만 R군이 컸다 (p > 0.05). 4. H군, R군은 1, 2, 3 mm 지점, M군은 1, 2 mm 지점에서 만곡외측으로의 변위를 보였고, 그 외의 지점에서는 내측변위를 보였다. 각 군 간의 변위차이는 6 mm 지점에서 H군이 컸다(p < 0.05). 5. 근관의 중심 이동률은 6 mm 지점에서 H군이 R군에 비해 유의하게 컸지만 다른 모든 위치에서는 차이가 없었다(p < 0.05). 본 실험결과를 토대로 할 때, 각 평가 항목에서 측정 위치에 따라 약간씩 차이가 있었으나, 중심 이동률은 대부분의 위치에서 유의한 차이가 없었다. 따라서 만곡 근관을 성형시에는 세 가지 방법 중 어느 것이 더 유용하다고 보기 어렵다고 판단된다. The purpose of this study was to compare the shaping ability of the three ProTaper instrumentation techniques in simulated canals. Thirty resin blocks were divided into 3 groups with 10 canals each. Each group was instrumented with manual ProTaper (Group M), rotary ProTaper (Group R), and hybrid technique (Group H). Canal preparation time was recorded. The images of pre- and post-instrumented root canals were scanned and superimposed. The amounts of canal deviation, total canal width, inner canal width, outer canal width and centering ratio were measured at apical 1, 2, 3, 4, 5 and 6 mm levels. 1. Canal preparation time was the shortest in R group (p <0.05). 2. The amounts of total canal width in R group was generally larger than the other groups, but no significant differences were observed except at the 1, 3 mm levels (p ) 0.05). 3. The amounts of inner canal width in R group was larger than M group at the 1 mm level and H group was larger than R group at the 6 mm level (p < 0.05). The amounts of outer canal width in R group was larger than H group only at the 1 mm level (p <0.05). 4. The direction of canal deviation in H, R group at the 1, 2, 3 mm levels was outward and that in M group at the I, 2 mm levels was inward. The amounts of canal deviation in H group was larger than R group at the 6 mm level (p <0.05). 5. The amounts of centering ratio in H group was larger than R group at the 6 mm level (p <0.05).
酸棗仁이 CT105에 의한 신경세포 상해 및 白鼠의 기억에 미치는 영향
정정욱,박창국,박치상,이소연,윤현덕,신오철 대한본초학회 2005 大韓本草學會誌 Vol.20 No.1
Objective: This study was designed to research whether demonstrate neuroprotective and memory enhancing effects of Z1BU, suggesting its beneficial actions for the treatment of AD. Methods: The present study investigated effects of the dichloromethane extract of Semen Zizyphi Spinosae(ZIBU) on neurotoxicity and reactive oxygen species(ROS) and nitric oxide(NO) formation in PC 12 cell line overexpressed with carboxyl-terminal 105 amino acid peptide fragment of amyloid precursor protein(CT105). In addition, the present study evaluated its radical scavenging activity and effects on acetylcholinesterase(AChE) activity. Furthermore, effects on neuronal loss in CAl area and cognitive deficits induced by scopolamine treatment were also evaluated in rats. Result: we found in this study that ZIBU significantly inhibited apoptotic neuronal death induced by CT105 overexpression in PC12 cells, with the IC_(50) value of 23 ㎍/ml. Based on phase-contrast and fluorescence microscopic examinations, ZIBU reversed morphological changes of CT105-expressed PC-12 cells. It was also found that Z1BU significantly induced neurite outgrowth and inhibited formation of ROS and NO.Z1BU scavenged DPPH radicals and inhibited AChE activity. Furthermore, it attenuated memory impairment induced by the injection of scopolamine in rats, based on passive avoidance test. Crystal violet staining of rat brain slices exhibited increase in the viability of pyramidal neurons in hippocampal CAI area. Conclusion: these results demonstrate neuroprotective and memory enhancing effects of ZIBU, suggesting its beneficial actions for the treatment of AD.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)
김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3
Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.
Early Growth, Carbohydrate and Phytic Acid Contents of Germinating Rice Seeds under NaCl Stress
Park So-Hyeon,Sung Jwa-Kyung,Lee Su-Yeon,Park Jae-Hong,Lee Ju-Young,Jang Byoung-Choon,Lee Ki-Sang,Song Beom-Heon,Kim Tae-Wan The Korean Society of Crop Science 2006 Korean journal of crop science Vol.51 No.2
Germination characteristics and alterations in soluble sugar-starch transition and phytic acid during germination were studied in rice seeds under saline conditions. NaCl significantly reduced the speed of germination. Also, the radicle growth out of seeds was severely inhibited by the exposure to NaCl solution, thus, seeds were almost impossible to grow to seedlings. Soluble sugar was remarkably accumulated, whereas starch was decomposed stepwise during seed germination. The metabolism of soluble sugar and starch in germinating seeds showed a distinct difference. The level of phytic acid in seeds decreased in all NaCl treatments during germination, but the level was affected differently by NaCl concentration in the two varieties. Overall, our results suggest that salt stress retard the radicle growth of rice seeds, and affect the starch-to-sugar conversion and the decomposition of phytic acid differently in two varieties.
So Young PARK,Eun Ji LEE,Nan Kyung KIM,So-Jeong KIM,Sun Jay YOON,Dong Nyoung OH,Sung Jin JEONG,Na Yeong BEEN,Ji Hyeon KIM,Da Yeong KIM,Jin Won CHOI,Won Je JANG,Jong Min LEE 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.10
Probiotics consumption has become a necessity in diet to metabolic syndrome. In this study, in vitro effects of anti-metabolic syndrome were confirmed on the probiotic strain isolated from feces. Each of the strain upregulated the mRNA expressions on zo-1, claudin-1 and occludin related to intestinal tight junction in human epithelial colorectal cell. In particular, the lactiplantibacillus treatment groups significantly upregulated the erk1/2 and map expression related to cell proliferation. In addition, the strain showed that upregulation of ppar-α related to fatty acid oxidation and downregulation of glut-2 related to glucose uptake. Based on the results of this study, we are conducting in vivo experiments to verify the efficacy of the probiotics for alleviating metabolic syndrome.
Changes of Ascorbic Acid and Nitrate Content in Lettuce by Unbalanced Nutrient Solution
Park, Yang-Ho,Park, So-Hyeon,Park, Jae-Hong,Lee, Ju-Young,Jang, Byoung-Choon,Lee, Ki-Sang The Korean Society of Crop Science 2006 한국작물학회지 Vol.51 No.1
This study was to verity that the uptake inhibition and accumulation of nitrogen in different potassium levels. Lettuce was used as model plant in this study and grown in pot of 10cm's in diameter and depth with mixture media of vermiculite and perlite under supply of different culture solution for three weeks. Nitrogen absorption at root was inhibited by increased potassium concentration in nutrient solution, and nitrate accumulation of plant was depended on absorption of nitrogen because nitrate content of 0 K level was 4-5 times higher than that of 2 K level, Concentration of ascorbic acid was decreased by increasing the nitrogen absorption, since ascorbic acid (AsA) content of 2K level was higher than those of OK level in both of old leaf and flesh leaf.