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오명돈,최강원,김병국,김재중,이홍규,김상윤 대한감염학회 1986 감염 Vol.18 No.2
Mucormycosis is an acute suppurative opportunistic mycosis that produce predominantly rhinocerebral disease in patient with diabetic ketoacidosis and immunosuppressed patient. We experienced two cases of rhinocerebral mucormycosis recently. The one occurred in patient with diabetic ketoacidosis and the other in acute leukemia. They showed nasal discharge, orbital cellulitis and proptosis. Their condition rapidly deteriorated. Biopsy from palate and sinus revealed broad, nonseptate, right-angled branching hyphae, a finding compatible with mucormycosis.
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진행 위암환자에서 Lymphokine-Activated Killer (LAK) 활성의 저하
홍원선,김영환,송재관,강윤구,이진오,강태웅,김정룡 대한내과학회 1990 대한내과학회지 Vol.38 No.3
Natural killer(NK) and lymphokine-activated killer(LAK) activities were determined in 31 patients with unresectable stomach cancer before and immediately after chemotherapy with 5-fluorouracil, adriamycin and mitomycin C(FAM) and 31 healthy volunteers. The major purposes of the study were focused on whether peripheral blood lymphocytes(PBL) in stomach cancer patients had a similar ability in the generation of LAK activity to those in healthy volunteers and what the effect was of chemotherapy with FAM on the generation of LAK activity. LAK cells were generated in vitro by culturing human PBL with 100 U/㎖ of recombinant human interleukin-2(rH-IL-2) for 72 hours. K562(human myelogenous leukemia cell line) and MKN-45(human stomach adenocarcinoma cell line) were used as target cells for NK and LAK activities. NK activity against K562, a sensitive line, was significantly depressed in patients with stomach cancer compared with that in healthy volunteers(p<0.01). However, LAK activity against K562 was similar to that of the controls. Age, sex and performance status(ECOG 0-2 and 3-4) did not have an influence on both NK and LAK activities. LAK activity was significantly higher than NK activity, either against K562 or MKN-45, in both healthy volunteers and patients with stomach cancer(p<0.001). NK and LAK activities against MKN-45, a NK-resistant line, in patients with stomach cancer showed significantly lower levels than those in healthy volunteers. We also analyzed the effect of chemotherapy with FAM on NK and LAK activities, with no suppression of NK and LAK activities being observed. In this study, we have demonstrated that PBL of stomach cancer have a reduced ability to generate LAK activity in response to rH-IL-2. However, LAK activity generated from PBL receiving chemotherapy with FAM was similar to that of PBL without chemotherapy.
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홍성철,오재욱,김수신,백세민,B.CELLIKOZ 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.6
Ankylosis of the mandible is a serious and most disabling condition. Impairment of speech, difficulty with mastication, poor oral hygience, facial asymmetiry, and mandibular micrognathia invariably result in much physical and psychologic disability, particularly in young children with complete inability to open the mouth. We performed a one stage reconstruction of temporomandibular joint at the same time as performing multiple additional oateotomies to correct the facial asymmetiry. Temporomandibular joint was reconstructed with costchondral graft or interpositional arthroplasty with silastic implant. Breakdown of 36 cases is as follows. 1. Most prevelent incidence is at age of 21-30 revealed no sex predilection. 2. Trauma was the most common cause, found in 8 patients. 3. Average preoperative mouth opening was 21mm and postroperative mouth opening was 39.8mm 27 patients with interincisor lengh greater than 30mm resumed a satisfactory life style with no discomfort. 4. Anethesia was done by fiberoptic nasotracheal intubation in 31 patients. 5. Postroperative complication included infection in 3 patients which was treated with local and systemic antibiotic therapy. 1 patient developed transient lower lip hypoesthesia.1 patient complained remained facial asymmetiry, which was corrected by fat injection. 6. In 20 patients simultaneous total correction of temporomandibular joint ankylosis and facial asymmetry were done.
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홍은혜,김성오,이제호,최형준,송흥규,최병재 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2
과잉치란 정상에 비해 많은 수의 치아를 일컫는 것으로 유치열기와 혼합치열기에 발생하며,여러 가지 임상적 문제를 일으킬 수 있다. 특히 상악 전치부의 과잉치는 상악 전치의 맹출 장애 및 전위,정중부의 치간 이개,치근 흡수,함치성 낭종 형성 등의 문제를 유발할 수 있으므로 조기에 진단하고,과잉치의 위치 및 수,형태에 따라 적절한 치료를 시행하는 것이 중요하다. 이 증례는 상악 전치부에 네 개의 과잉치가 영구치의 맹출을 방해하고 있는 경우로,발거 시 합병증을 최소화하기 위하여 두 단계로 나누어 발거하였다. 컴퓨터 단층 촬영에서 네 개의 과잉치가 주위의 영구치 맹출을 방해하고 있었고,그 중 두 개의 과잉치는 절치 치배에 매우 근접해 있었다. 네 개의 과잉치를 동시에 제거할 경우 영구 치배에 손상을 줄 위험이 있으므로 두 개의 역위 매복된 원추형의 과잉치만 먼저 발거하였다. 남은 두 개의 과잉치는 위치가 변화되기를 기다린 후 두 번째 발거 수술을 시행하여,주위 절치 치배에 손상을 가하지 않고 치조골 삭제를 적게 하여 합병증 발생을 줄일 수 있었다. Supernumerary teeth are characterized by an excess number of teeth, which can be responsible for a variety of irregularities in the primary and transitional dentition, Supernumerary teeth, especially in the maxillary anterior region, may prevent the eruption of adjacent permanent teeth and cause their ectopic eruption, diastema, root resorption, or formation of dentigerous cyst. Therefore, early diagnosis of supernumerary teeth is important for prevention of such complications, and adequate treatment should be given according to their location, number, and morphologic features. In this case. four supernumerary teeth in the maxillary anterior region were disturbing the eruption of adjacent permanent incisors. Two of them were located in proximity to the central incisor tooth germs that their immediate removal may injure the permanent tooth germs, In order to minimize such complications, surgical extraction of the four supernumerary teeth was performed in two stages. At first, only two inverted conical supernumerary teeth were extracted. The other two tuberculous supernumerary teeth, close to the permanent tooth germs, were extracted later after their natural dislocation, In that way, we could minimize affects on the neighboring permanent tooth germs and also the amount of alveolar bone removed during surgery.
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CNC 선반에서 볼 나사 열변형에 따른 위치결정 정도 개선에 관한 연구
홍성오,조규재,김재열 한국공작기계학회 1999 한국생산제조학회지 Vol.8 No.1
Thermal expansion of the ball screw can directly affect the accuracy of positioning along the ravel axis in the semi-closed loop type CNC Lathe. In this paper, use of MACRO variables can make the thermal displacement of the ball screw estimated. Also, the estimated displacements of the ball screw are controlled by calculation the interval of pitch error rate in the Numerical Control(NC). Under the constant operating conditions, the thermal expansion of the ball screw was measured to confirm the effectiveness of the compensation method in the CMC Lathe. By using this method the results show that the thermal displacement of the ball screw could be reduced to 20% compared with ordinary method.
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