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자외선 경화형 아크릴 모노머를 통한 옻칠 개질 및 코팅 물성 연구
홍진후,박미영,김현경,박기주 조선대학교 생산기술연구소 1998 生産技術硏究 Vol.20 No.2
UV-Curable acryl monomer containing quaternary ammonium salt has been synthesised and Introduced into the orintal lacquer by dual curing method. Electrical and thermal mechanical properties were studied in view of the interpenetrating polymer network theory. Although modification of oriental lacquer could not introduce antistatic properties into coating network, tremendous improvement in the properties of breaking voltage was observed.
Real-Time IR을 이용한 Polyesterimide의 경화거동 연구
홍진후,송주명,김현경,박미영,박기주 조선대학교 생산기술연구소 1999 生産技術硏究 Vol.21 No.2
Polyesterimide for enamel Wire coating was synthesized and its curing reaction was monitored by real-time FT-IR. Infrared 1019cm^(-1) band was used to monitor the curing process. Results of in-situ analysis showed that evaporation of ethylene glycol and transesterification started from 100℃. When curing temperature was higher than 200℃, ester reaction was favored over the ether reaction. It was concluded that curing temperature is the key factor to control the thermal stability of the enamel wire coating.
홍진후,박미영,김현경 조선대학교 생산기술연구소 1999 生産技術硏究 Vol.21 No.2
The curing of diglycidyl ether of bisphenol A (DGEBA) with triethyl-enetetramine (TETA) under controlled thermal conditions was discussed. A real-time FT-IR ATR was employed to determine crosslinking reactions and degree of cure. Infrared 914cm^(-1) band was used to monitor the conversion of the reactions. To measure the thermal mechanical properties of the various systems, DMTA was employed. Results of ATR and DMTA data show that optimum TETA/DGEBA ratio was about 0.1. When the ratio was higer than 0.1. a phase separation was occurred with short pot life. It is demonstrated that real-time FT-IR ATR is powerful technique to better understand the formulation-process-property relationship of the Epoxy ITETA system.
면접조사를 통한 초등학생의 영양교육 실태 및 실천도 조사
오유진,이영미,김정현,안홍석,김정원,박혜련,서정숙,김경원,권오란,박혜경,이은주,성현이 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4
This study investigated the experience and practice of elementary school students on nutrition education. The data were collected from 217 male and female students attending 5-6th grade elementary schools in Seoul and Kyunggi-Do from March to June 2007, interviewing face to face by a nutrition teacher and 3 interns of a nutrition teacher. The results were as follows: 86.5% of the subjects learned about ‘Table etiquette’, ‘Reasons for eating fruits and vegetables’ (78.7%), ‘Food waste and environment’ (72.3%), ‘Healthy snacks’ (55.7%), ‘Food sanitation’ (52.3%), ‘Food culture of foreign countries’ (48.1%). Nutrition education experience was significantly different by gender. A total of 43.5% boys responded that they never learned about ‘basic food preperation’ (p < 0.01). They had learned ‘Nutrients for body’ and ‘Food waste and environment’ in school, ‘Healthy weight loss’, ‘Food culture of foreign countries’, ‘Food circulation’ on television, Most content (‘Table etiquette’, ‘Simple cooking’, ‘Food sanitati n’, ‘Eating behaviors for health’, ‘Reasons for eating fruits and vegetables’, ‘Healthy snacks’) was learned from parents. The practice after nutrition education was higher in ‘Table etiquette’ (2.14), ‘Eating fruits and vegetables’ (2.07) than others compared with education experience. The most reason of non-practice on nutrition information was ‘Troublesome’. In ‘Nutrients for body’, a boy answered ‘Difficult for practice’ 20.0%, a girl answered ‘Difficult to understand’ 32.6%, showing a significant difference between the gender groups (p < 0.001). They remembered the ‘Nutrients for body’ (49.6%), ‘Food sanitation’ (44.5%) because of ‘important content’,‘Basic food preparation’ (40.6%), ‘Food culture of foreign countries’ (36.3%) because of ‘interesting content’, ‘Healthy weight loss’ (52.0%), ‘Eating behavior for health’ (44.5%) and ‘Healthy snacks’ (33.7%) because of ‘need for my health’.
열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구
배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2
Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.
Hong, Oak-Kee,Yoo, Soon-Jib,Son, Jang-Won,Kim, Mee-Kyoung,Baek, Ki-Hyun,Song, Ki-Ho,Cha, Bong-Yun,Jo, Hanjoong,Kwon, Hyuk-Sang The Korean Society of Pharmacology 2016 The Korean Journal of Physiology & Pharmacology Vol.20 No.2
Here, we investigated whether hyperglycemia and/or free fatty acids (palmitate, PAL) affect the expression level of bone morphogenic protein 4 (BMP4), a proatherogenic marker, in endothelial cells and the potential role of BMP4 in diabetic vascular complications. To measure BMP4 expression, human umbilical vein endothelial cells (HUVECs) were exposed to high glucose concentrations and/or PAL for 24 or 72 h, and the effects of these treatments on the expression levels of adhesion molecules and reactive oxygen species (ROS) were examined. BMP4 loss-of-function status was achieved via transfection of a BMP4-specific siRNA. High glucose levels increased BMP4 expression in HUVECs in a dose-dependent manner. PAL potentiated such expression. The levels of adhesion molecules and ROS production increased upon treatment with high glucose and/or PAL, but this eff ect was negated when BMP4 was knocked down via siRNA. Signaling of BMP4, a pro-inflammatory and pro-atherogenic cytokine marker, was increased by hyperglycemia and PAL. BMP4 induced the expression of inflammatory adhesion molecules and ROS production. Our work suggests that BMP4 plays a role in atherogenesis induced by high glucose levels and/or PAL.
Hypermethylation of <i>p16<sup>INK4a</sup></i> in Korean Non-small Cell Lung Cancer Patients
Hong, Young-Seoub,Roh, Mee-Sook,Kim, Na-Young,Lee, Hye-Jung,Kim, Hee-Kyoung,Lee, Kyung-Eun,Kwak, Jong-Young,Kim, Joon-Youn KOREAN ACADEMY OF MEDICAL SCIENCE 2007 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.22//SUP No.-
<P>Promoter hypermethylation of the <I>p16<SUP>INK4a</SUP></I> gene was investigated in 81 sets of samples of tumor tissue and adjacent normal tissue from Korean patients with primary lung cancer, using the modified real-time polymerase chain reaction (PCR)/ SYBR Green detection method. The results showed hypermethylation of <I>p16<SUP>INK4a</SUP></I> in 27.2% of tumor tissues, and in 11.1% of adjacent normal tissue. No significant association was found between the overall aberrant methylation in tumor and corresponding normal specimens (r=0.137, <I>p</I>=0.219). In 22 cases with <I>p16<SUP>INK4a</SUP></I> hypermethylation in tumor tissues, only 4 (18.1%) cases were found to have a hypermethylated normal tissue specimen. The findings of this study show that smoking can influence the methylation level of the promoter region of <I>p16<SUP>INK4a</SUP></I>, and that this occurs in tumor tissues more frequently than in normal tissues. Other clinicopathological characteristics, including age, sex, tumor stage, and histologic type were not found to be correlated with <I>p16<SUP>INK4a</SUP></I> methylation.</P>
( Kyoung Min Moon ),( Ga Eun Kim ),( Soon Koo Baik ),( Eun Hee Choi ),( Moon Young Kim ),( Hyoun A Kim ),( Mee Yon Cho ),( Seung Yong Shin ),( Jung Min Kim ),( Hong Jun Park ),( Sang Ok Kwon ),( Young 대한간학회 2013 Clinical and Molecular Hepatology(대한간학회지) Vol.19 No.4
Background/Aims: We compared the cirrhosis-prediction accuracy of an ultrasonographic scoring system (USSS) combining six representative sonographic indices with that of liver stiffness measurement (LSM) by transient elastography, and prospectively investigated the correlation between the USSS score and LSM in predicting cirrhosis. Methods: Two hundred and thirty patients with chronic liver diseases (187 men, 43 women; age, 50.4±9.5 y, mean±SD) were enrolled in this prospective study. The USSS produces a combined score for nodularity of the liver surface and edge, parenchyma echogenicity, presence of right-lobe atrophy, spleen size, splenic vein diameter, and abnormality of the hepatic vein waveform. The correlations of the USSS score and LSM with that of a pathological liver biopsy (METAVIR scoring system: F0.F4) were evaluated. Results: The mean USSS score and LSM were 7.2 and 38.0 kPa, respectively, in patients with histologically overt cirrhosis (F4, P=0.017) and 4.3 and 22.1 kPa in patients with fibrotic change without overt cirrhosis (F0.F3) (P=0.025). The areas under the receiver operating characteristic (ROC) curves of the USSS score and LSM for F4 patients were 0.849 and 0.729, respectively. On the basis of ROC curves, criteria of USSS ≥6: LSM ≥17.4 had a sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 89.2%:77.6%, 69.4%:61.4%, 86.5%:83.7%, 74.6%:51.9% and 0.83:0.73, respectively, in predicting F4. Conclusions: The results indicate that this USSS has comparable effi cacy to LSM in the diagnosis of cirrhosis.