Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

우심방을 침범한 거대 비호지킨씨 림프종 1예

강상범,진승원,이은경,박용현,최용호,김용주,박준철,김재형,홍순조,최규보,권종범,원용순,박건,이은희 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

정밀부품 및 기기에 대한 환경시험기술

최만용,박정학,윤규택 한국비파괴검사학회 2001 한국비파괴검사학회지 Vol.21 No.6

정밀부품이나 기기는 개발과정이나 완료단계에서 부적절한 설계에 의하여 발생할지도 모르는 잠재적인 결함을 방지하기 위하여 시험평가를 실시하게 된다. 본 논문에서는 신뢰성 기술 분야의 기초가 되는 환경시험기술을 소개 하였으며 엔코더, 교통신호제어기, 계측기기 및 위성항법 수신기 등 제품단위의 대상품에 대한 시험조건 및 방법 등을 기술하고 시험사례를 보고하였다. 이러한 사례를 통하여 제품의 신뢰성 향상을 위한 복합환경시험의 중요성을 강조하였고 최근 환경시험기술에 대한 인식이 날로 증대되면서 시험기술자 양성, 지그설계기술 그리고 고장해석 및 대책기술의 확보가 매우 필요함을 제안하였다. Precision parts and instruments are tested to evaluate performance in development-process and product-step to prement a potential defect due to a failure design. In this paper, Environmental test technology, which is the basis of reliability analysis, is introduced with examples of test criterion, test method for products, encoder and traffic signal controller, and measuring instruments. Recently, as the importance of the environmental test technology is recognized, It is proposed that tranining of test technician and technology of jig design and failure analysis are very essential.

일부 산업재해 환자들에서 외상후 스트레스장애

최경숙,임채기,최재욱,강성규,염용태 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.3

연구목적 : 우리나라에서 산업 재해로 신체적 손상을 입고 입원해 있는 일부 근로자들을 대상으로 PTSD 발병여부를 조사하고, 산업 재해와 관련된 위험 인자를 파악하여 산업재해 이후 근로자들이 겪게 될 신체적 건강문제 뿐만 아니라 정신적 건장 문제 회복에 도움을 주고자 하였다. 방 법 : 2000년 7월에서 2000년 9월 사이에 산업 재해로 인해 신체적인 부상을 입고 입원 중인 인천 소재 산재병원의 남성 입원환자 47명을 대상으로 PTSD 발병여부와 관련 인자를 연구하기 위하여 구조화된 설문 조사와 CAPS를 이용한 진단적 면담을 시행하였다. 결 과 : CAPS를 이용한 면접조사 결과 최종 연구 대상자 47명중 12명(25.5%)이 PTSD로 나타났으며, 모두 증상의 지속 기간이 3개월 이상인 만성 외상후 스트레스장애로 분류되었다. PTSD군 12명과 non-PTSD군 45명을 비교한 결과 BDI, STAI-I, STAI-II, IES 점수는 PTSD 군에서 유의하게 높게 나타났다. 또한 SCR-90-R의 세부항목 중 편집 사고를 나타내는 PAR 점수가 유일하게 두 군 사이에 유의한 차이를 보이지 않았고 그 외의 항목들은 PTSD 군에서 유의하게 높았다. 산재 관련 위험 인자의 비교에서 환자가 주관적으로 보고한 의식의 상실 경험만이 PTSD군에서 유의하게 높게 나타나 이전의 다른 연구자와 일치된 소견을 보였다. 결 론 : 이상의 결과는 산재 사고 이후에 PTSD가 발생하고, 증상이 장기간 지속되어 만성화를 겪을 가능성이 있다는 것을 보여준다. 위험 인자 중에서 사고 관련 위험 인자로 의식의 상실에 대한 주관적인 보고만이 관련성이 있는 것으로 나타났으나, 그 외의 다른 인자들은 관련서이 없는 것으로 나타났다. 그러나 여러 가지 연구의 제한점이 많으므로 연구 시점을 달리하고 많은 대상자를 포함한 후속 연구를 시행해야 산업재해와 PTSD에 대한 이해를 높일 수 있을 것으로 사료된다. Objectives : This study was conducted to assess the development of posttraumatic stress disorder(PTSD) after occupational physical injuries and the risk factors in occupational accident patients for PTSD. Methods : Forty-seven occupational accident patients with physical injuries were administered BDI. STAI I and II, SCL-90-R, IES and questionnaires for risk factors and Clinician-Administered PTSD Scale(CAPS). Results : 1) 12 patients(25%) were diagnosed as PTSD. 2) The BDI, STAI I and II and IES scores are significantly high(<0.05) in PTSD group than non-PTSD group. 3) The subscales of SCL-90-R, with an exception of PAR subscale, showed higher scores(<0.05) in PTSD group. 4) The loss of consciousness(LOC) was only significant risk factor in the occupational accident related factors(<0.05). Conclusion : The results of this study show the development of PTSD among occupational accident patients. The loss of consciousness(LOC) was the only significant risk factor for PTSD in occupational accident patients.

現代地籍理論의 體系化 構想(Ⅱ)

崔龍奎 청주대학교 사회과학연구소 1991 한국사회과학연구 Vol.10 No.-

The government, regarding the problem of land as one of the most important policies, has made every effort for settling an ever-increasing serious problem of land. The theory of land registration and management is a science which surveys the present state of land, records the present state, manages the recorded content, and operates them, and the land registration and management is understood as the official register recording the informations of the land. The more the importance of land is stressed to the modern people, the more the academic studies is increased. The theory of land registration and management which has been developed on a working level until now shall be developed to an academic study according to a request of the times. Therefore, this study comprehends (1) The academic necessity and character of the land registration and management, (2) The subject and scope of study of the land registration and management, (3) The approach to the land registration and management, and this is the latter part of the systemized concrete of the modern theory of the land registration and management.

역사 학습에서의 의사결정

최용규 韓國社會科敎育硏究會 1997 社會科敎育學硏究 Vol.- No.1

Semiclassical Analysis for O + Pb Elastic Scattering at E=216.6 and 312.6 Mev

최치규,현남규,김용주,홍성락 제주대학교 1992 논문집 Vol.34 No.-

실험실계에서의 입사핵?? 에너지가 216.6과 312.6 MeV이고 표적핵?? 인 탄성산란에 대한 실험데이타를 수정된 Glauber모델을 사용하여 분석하였다. 계산된 결과들은 실험데이타와 좋은 일치를 보여주었다. .

6주간의 淸暑益氣湯 經口投與가 에너지대사 및 호르몬 변화에 미치는 영향

최용어,강명신,유종만,이규성,오재근,조준용 韓國體育大學校附屬 體育科學硏究所 1994 韓國體育大學校附屬 體育科學硏究所論文集 Vol.13 No.1

The purpose of this study was to investigate the effects of chung-seo-ik-gi -tang administration on the metabolic responses and hormones in 18 healthy-male elite boxes. All subjects were divided randomly with two groups, Chung-sea-ik-gi-tang Group(N=18) and placebo group(N=18) and perfored with 70% of HR max using bycicle ergometer unfil exhaustion. During the submaximal exercise, heart rate was maesured every two min. The blood samples were collected from antecubital vein by 10ml syranges(6ml/each) before immediately after exhaustion, recover-10 min, recover-20 min and recover-30 min. The samples were to analyzed for the level of glucose, lactate, TG, TC, HDL-C, insulin and catecholamine. The results of various blood parameters were summarized as follow; l. Energy substrates (plasma glucose, TG, TC, HDL-C) changes in group C were significantly different from group P. Plasma glucose in group C was significantly lowered at recover-10 min compared to group P (P<0.05). and also TG, TC and HDL-C in group C were significantly increased after 3 weeks compared to group P (P<0.05) whereas. Lactate accumulation in group C was significantly decreased after 3 weeks compared to group P (P<0.05). 2. Plasma insulin level was not showed significant difference between two groups. But insulin depression tendency after 3, 6 weeks in group C was allevated compared to group P. Increasing rate of norepinephrine in group C at Post-exhaustion after 3weeks lowered compared to group P. Norepinephrine in group C at rest periods after 3 weeks showed significant difference compared to group C. The results indicated that Chung-seo-ik-gi-tang had the effects of ergogenic aids on fatigue resistance and recovery from exhaustive exercise at the level of 70% HR max.

새마을運動과 土地政策의 住民參與

崔龍奎 청주대학교 새마을연구소 1989 새마을硏究論文集 Vol.6 No.-

Saemaul Undong started in 1970 to be driven to arrange the small cities for the purpose of improving the rural surrounding. Then Saemaul Undong was spreaded over every work place including the rurals and cities over the country of Korea through an experimental stages. The main purposes of Saemaul Undong are the development of spirit, the improvement of environment and the increase of income, and war driven on the basis of the principle of general development. The spirit is a movement to render service to the national development by accomplishing the development of spirit and the economical development with a trnity of village people, village leader, and government together on the basis of self-support, self-reliance and cooperation. Therefore, Saemaul Undong is a pan-national movement of effort for the modernization of fatherland by promoting self-development in order that the village people as well as nationals may better theirselves' life. Now Semaul Undong needs the voluntary participation of people at the time when the local self-government will be realized in the near future. In this paper, Saemaul Undong and the policy in order to take effect on the importance of land shall be realized under the positive participation of people of Saemaul Undong and policy of land. The content of the statement of this theory has a case that the people residing in Mokdong of citizen participated in the development of Mokdong area.

고교 물리교육과정 변천에 관한 비교 연구 : 에너지 단원을 중심으로

최원식,김규용 濟州大學校 師範大學 科學敎育硏究所 1987 科學敎育 Vol.4 No.-

Whenever there have been reforms of the high school curricula, the contents and formation of physics education have also been changed much. Especially the Energy parts has influenced not only various fields of studies but also our daily lives. Recently the influence is increasingly striking Therefore, how to instruct physics, especially Energy parts, at high school level should be carefully considered Thus, the changes in Energy parts at high school level dut to the several stages of the curricular reforms since 1945 should be analyzed. Particular emphasis should be given in change of the level and method of physics instruction as well as physics experiments contained in the text books.