Kim's Femoral Stem의 임상적 고찰

김영민(Young Min Kim),김희중(Hee Joong Kim),진종수(Jong Soo Jin),문영완(Young Wan Moon) 대한정형외과학회 1991 대한정형외과학회지 Vol.26 No.5

관상동맥 질환에서 CD14 유전자형에 따른 세균 및 Heat Shock Protein에 대한 반응의 차이

한주용,최수연,조현주,김화평,강현재,구본권,김남중,김효수,손대원,오병희,박영배,최윤식 대한감염학회 2007 감염과 화학요법 Vol.39 No.1

Background : CD14 is the receptor for lipopolysaccharides and heat shock protein (HSP), which has been suggested being associated with increased risk of coronary artery disease (CAD). We investigated whether the response to infectious agents or HSP is different according to CD14 polymorphism in Koreans. Materials and Methods : Antibody titers to Helicobacter pylori, Chlamydia pneumoniae, and human HSP60 (hHSP60) were measured in 48 patients with stable CAD and in 41 healthy controls by ELISA. CD14 genotype was determined by PCR and high-sensitivity C-reactive protein (hs-CRP) was measured. Results : Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly associated with the presence of CAD. CD14 genotype distribution was 31 TT (35%), 43 CT (48%), and 15 CC (17%). To compare the response to the infectious organism and hHSP60, we divided study population into 3 groups; CAD patients with non-TT genotype (group I, n=30), CAD patients with TT genotype (group II, n=18), and normal controls (group III, n=41). Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly different among 3 groups. Though hs-CRP level was significantly different among 3 groups, post-Hoc analysis showed that hs-CRP level was not significantly different between group I and group II (group I: 1.6[1.1-3.5] mg/L and group II: 0.35[0.1-2.0] mg/L). Conclusions : This study suggests that the inflammatory responses to infectious organisms and HSP do not differ according to the CD14 genotype in Koreans. 목적 : 만성적인 세균 감염이나 자가 면역 반응이 동맥경화와 연관되어 있다는 주장이 제기되어 왔다. CD14은 lipopolysaccharides (LPS)와 heat shock protein(HSP)의 수용체로 C(-260)→T 다형성이 관상동맥 질환의 위험과 관련되어 있다고 제안되어 왔다. 본 연구에서는 한국인에서 CD14 다형성에 따른 LPS와 HSP에 대한 반응성을 염증표지자를 측정하여 살펴보고자 하였다. 재료 및 방법 : 안정형 관상동맥 환자 48명과 정상 대조군 41명을 대상으로 Chlamydia pneumoniae, Helicobacter pylori 항체 및 인체 HSP60 (hHSP60) 항체 역가를 enzyme-linked immunosorbent assay (ELISA) 방법으로 측정하였다. CD14 유전자형은 중합효소연쇄반응을 이용하여 결정하였고 hs-CRP를 측정하였다. 결과 : C. pneumonias 및 H. pylori 항체 양성 여부 및 항체 역가, 그리고 hHSP60에 대한 항체 역가는 안정형 관상동맥 질환의 유무와 유의한 상관관계는 없었다. CD14 유전자형의 분포는 TT 30명(39%), CT 31명(40%), 그리고 CC 16명(21%)이었다. 관상동맥 질환 군에서 TT 유전자형은 38%, 대조군에서는 32%로 TT 유전자형과 관상동맥 질환의 유무와는 유의한 상관관계가 발견되지 않았다(P>0.05). CD14 유전자형에 따라 C. pneumonias와 H.pylori 감염 및 hHSP60에 따른 반응에 차이가 있는지 여 부를 알아보기 위해, 관상동맥 질환 군을 다시 TT 유전자형 군과 non-TT 유전자형 군으로 나누어, 전체적으로 세군에서 항체 양성률과 역가를 비교하였다(I군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, II군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, III군: 정상 대조군). 세 군에서 C. pneumonias와 H. pylori 항체 양성률 및 hHSP60 항체 역가에는 유의한 차이가 없었다. 세 군사이에 hs-CRP 값에 유의한 차이가 있었지만, post-Hoc분석에서 II군의 hs-CRP 값이 I군에 비해 유의하게 높지는 않았다(0.35 [0.1-2.0] mg/L in group II vs. 1.6 [1.1-3.5]mg/L in group I, P>0.05). 결론 : 본 연구는 한국인에서 CD14 유전자형에 따라 LPS나 HSP에 대한 반응이 유의하게 다르지 않음을 시사한다.

찻물에서의 Cd과 Pb 이온 제거에 관한 차입자의 효과

김중만,백승화,박성수 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.5

차재료를 찻물에 담근 후 차건데기를 건저내고 마시는 차류의 중금속 제거력을 조사하기 위하여 Cd과 Pb 용액에서 보리차, 옥수수차, 쟈스민차, 현미녹차, 홍차, 결명자차, 감껍질차, 귤껍질차, 누룽지의 입자별, 농도별, 온도별 제거 정도를 조사한 결과는 다음과 같다. 입자의 크기가 작아질수록 모든 차에 있어서 중금속 제거력은 증가되었고, 금속별 제거량은 Cd는 결명자차(3.253∼6.136㎎/g)가, Pb은 쟈스민차(6.784∼7.557㎎/g)가 높았다. 농도별 중금속 제거량은 중금속의 농도가 증가할수록 증가하였는데 Cd와 Pb는 쟈스민차(1.209∼4.815㎎/g, 0.642∼7.004㎎/g)가 제거력이 높았다. 농도별 중금속의 제거작용은 모든 차류에서 증가되었으나 옥수수차는 Pb에서 0.497∼0.647㎎/g로 제일 낮았다. 온도별 중금속 제거량은 온도가 높아질수록 증가하여 Cd은 결명자차가 4.080∼7.799㎎/g, Pb는 쟈스민차가 7.003∼7.763㎎/g으로 증가하는 경향을 보였다. Removabilities of heavy metals(Cd and Pb) by the tea materials (barley-tea, corn-tea, jasmin-tea, brown rice-green tea, cassia tora-tea, persimmon peel-tea, orange peel-tea and rice-tea) in the tea-water were studied in the various conditions ; particle size of tea(20, 40, 70 mesh), concentration of heavy metal(25, 50, 100 ppm) and extraction temperature(20, 30, 50, 100℃). The removabilities by the tea solids were increased as the particle size decreased, concentration of heavy metal increased, and extracting temperature increased. Of the nine kinds of tea, Cd and Pb removability by jasmin-tea was highest. In addition, heavy metal removability by cassia tora tea was better than that of other tea as extraction temperature was increased.

방사선 조사식품의 검지법

김경수,양재승,권중호 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

간과된 건성 추지의 수술적 치료

김융성,서중배,이석재,홍장수 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.2

연구목적 . 손상 후 3주 이상 경과된 건성 추지에 대하여 tuft를 만들어 주고 신전상태에서 K-강선으로 고정하는 수술적 치료 방법의 유용성을 분석하고자 하였다. 대상 및 방범: 1997년 8월부터 2001년 3월까지 본 교실에서 건성 추지로 치료받은 예 중 손상 후부터 3주 이상 경과된 환자 11예를 대상으로 하였다. 평균 추시 기간은 7개월(3개월-9개월)이었으며, 평균 연령은 19세(2년 3개월-48세)였다. 11예 중 4예는 15세 미만의 소아였다. 수상 후 수술까지 경과된 기간은 평균 12개월(3주-7년)이었다. 우측 수부가 7예였고, 좌측은 4예였다 수지 별로는 인지가 3예, 중지가 4예, 약지가 2예, 소지가 2예였다. 모든 예에서 신전건의 절단, K-강선에 의한 원위지 관절의 고정, tuft의 형성, Roll-stitch 등의 동일한 방법을 사용하였으며, 최종 추시일에 Crawford 평가방법을 사용하여 환자를 평가하였다. 결과: Crawford의 방법을 이용한 평가 결과, 11예 중 7예(64%)가 우수(Excellent)의 결과를 보였고, 3예(27%)는 우량(Good), 1예(9%)는 양호(Fair)로 판명되었다. 즉 11예 중 1예를 제외하고는 모두, 즉 91%에서 만족스런 결과를 얻었다 우량 또는 양호의 결과를 보였던 4예의 경우 수상 후 경과된 기간이 각각 4개월, 9개월, 3년, 7년으로 수상 후 경과된 기간이 길수록 결과가 나빴다. 15세 미만의 소아 4예는 모두 우수한(Excellent) 결과를 보였고, 반면에 양호로 판정된 환자는 연령이 48세로 대상 환자 중 가장 고령이었다. 손상된 수지가 좌측이거나 우측인지 여부와 몇 번째 수지인지 여부는 결과와 무관한 것으로 보인다. 성별과도 관련성을 알 수 없었다. 결론: 손상 후 상당기간이 경과한 후에도 비교적 간단한 수술 방법에 의한 치료가 가능하였으며, 결과도 만족스러웠으나, 지나치게 오래된(손상 후 수 개월 이상이 경과한) 건성 추지의 경우, 그리고 나이가 많은 경우 예후가 좋지 않다는 사실을 알게 되었다. Purpose : The authors have attempted to analyze the effectiveness of making tuft and fixing the distal interphalangeal joint in extension with a K-wire in patients whose injured finger were left over 3 weeks without treatment for the tendinous mallet finger. Materials and Methods : Eleven fingers of eleven patients were analyzed who were treated operatively from August 1997 to March 2001. The average follow-up period was 7 months(3-9 months). The average age of the patients was 19 years(2 years 3 months-48 years) Four out of the 11 cases were children under age of 15. The average duration between injury and operation was 12 months(3 weeks-7 years) . All cases were treated by only one surgeon(Seo, JB) and with same procedure, just cutting and reattaching the extensor tendon tightly(tuft) and fixing the joint in extension. Crawford method was used for evaluating the patients. Results : Ten out of eleven patients(91%) came out to be satisfactory according to Crawford method. Excellent in 7 cases, good in 3, fair in 1, respectively. Four patients whose duration between injury and surgery seemed to be too long(4 months, 9 months, 3 years, 7 years respectively), have not showed excellent results. Excellent results were reported in all children. On the contrary, the age of the patient who had the poorest result was 48 years(the oldest in our series) Which hands or which fingers were injured seemed to have not made any differences. So as the surgery was performed earlier and the patients were younger, the results were better. Conclusion : We advocate that it is possible to treat operatively and to get good results in Patients with neglected mallet finger deformities. But it should be emphasized that the earlier the operation is performed, and the younger the patients are, the better the results are.

3중채널 입체음향 通信系統의 兩立性에 關한 硏究

金秀重,文相在 慶北大學校 1975 論文集 Vol.19 No.-

The compatibility of three-channel stereophonic system with monochannel system and two-channel stereophonic system has been investigated. Algebraic approach to analyzing the compatibility of multichannel stereophonic system with monochannel system shows that the three-channel stereophonic system is not fully compatible with two-channel stereophonic system, in comparision with the compatibility of two-channel stereophonic system with monchannel system.

돼지에서 개량된 회장 캐눌러 삽관법 1례

김명철,이재일,이수진,조종민,김남중 충남대학교 수의과대학 동물의과학연구소 2001 動物醫科學硏究誌 Vol.9 No.-

Intestinal cannulation was developed for the study of enteric microflora, nutritional requirements and status. However, already established techniques revealed cause often leakage of the intestinal contents and necrosis of skin. For the prevention of contamination from the ingesta, modified ileal cannulation was performed in a pig. The pig was anesthetized by tiletamine-zolazepam(4.4㎎/㎏, IM) administration 10 minutes after administration of xylazine(0.5㎎/㎏, IM). We inserted resin cannula in the ileum incised and put the inner ring after employing purse-string suture in the ileum. We made the puncture incision in the body wall through which the cannula is drawn. The cannula was placed surgically at the ventral placement of cranial part and at the dorsal placement of caudal part. Cannula was fixed by placement of two outer washer, and sealed with cannula stopper. Laparotomy incision was closed by mattress suture. The pig was given postoperative penicillin(20,000 IU/㎏ IM) to prevent secondary infection for 3 days. There were not observed the entering of rubber cannula into the abdominal cavity, the contamination of ingesta and necrosis of skin, and good result was revealed.

폐좌상시 폐단락률과 PEEP치료의 효과

김영식,황성오,최경훈,안무업,오중환,임경수,윤정환,강성준 大韓應急醫學會 1992 대한응급의학회지 Vol.3 No.1

To evaluate the physiologic extent of pulmonary contusion and effect of PEEP therapy for pulmonary contusion, we studied 16 patients received PEEP therapy with pulmonary contusion from nonpenetrating chest trauma. Hemodynamic parameters including pulmonary vascular resistance index and intrapulmonary shunt fraction were calculated from standard measurement, and arterial oxygen tension was measured. Pulmonary vascular resistance index and intrapulmonary shunt fraction were increased in patient group. Arterial oxygen tension was decreased with increase of the intrapulmonary shunt fraction(R=0.75). Arter minimal PEEP therap(5-10 ㎝H₂O), pulmonary vascular resistance index was remained unchanged and intrapulmonary shunt fraction was decreased without significant changes of pulmonary hemodynamics. Increment of arterial tension was increased with decrease of intrapulmonary shunt fraction(R=0.43). Decreased stroke volume index suggested of cardiac injury such as cardiac contusion in patient group. These results of our study suggested that increased intrapulmonary shunt fraction caused arterial hypoxia in pulmonary contusion and arterial oxygen tension was increased as a result of reduced intrapulmonary shunt by PEEP therapy.

Gunn Diode Dipole Layer Mode의 周波數 特性

金秀重,朴成漢 경북대학교 공과대학 1974 工大硏究誌 Vol.3 No.-

When the n_0L product is greater than 10^12 cm^-2 in n-GaAs, the space charge perturbation in the material increases exponentially in space and time to form mature dipole layer which propagate to the anode. This is due to the inherent differential negative resistance characteristics of bulk n-GaAS. A velocity-field equation, whose characteristic is similar to that given by Ruch and Kino, was derived from the McCumber and Cynoweth's temperature model of electron distribution. Using this equation, a computer analysis was made to find out the variation of frequency of the Dipole Layer Mode of Gunn Oscillator due to the variation of notch width and doping donsity in n-GaAs bar. The result showed that the frequency is more affected by width than by doping density variation of the notch.

骨盤腔內 巨大 橫紋筋肉腫 1 例

金瑩洙,河泰原,朴滿洙,姜瞬求,李重禾,尹栗老,薛鍾求 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

Rhabdomyosarcoma, which is a very rare and highly malignant disease in urologic field, has three categories-pleomorphic, alveolar, embryonal, and may arise from any part of the body that contains embryonal mesenchyme, whether striated muscle tissue is present or not. The common site in the genitourinary tract are prostate, bladder, and vagina. Herein we experienced a rhabdomyosarcoma of the pelvic cavity and reviewed literature briefly.