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      • KCI등재

        분지각이 작고 일시 개화성이 우수한 숙근 안개초 ‘드림송’ 육성

        정동춘(Dong-Chun Cheong),최창학(Chang-Hak Choi),송영주(Young-Ju Song),김정만(Jeong-Man Kim),이진재(Jin-Je Lee) 한국원예학회 2014 원예과학기술지 Vol.32 No.4

        ‘Bristol Fairy’ 유래의 결실되는 아조변이체인 ‘Gyp99’의 실생계통으로 밝은 백색 겹꽃에 소화가 큰 ‘Gyp06-11’로부터 2008년 특성이 우수한 ‘Gyp08-2’ 계통을 선발하여 2009-2010년 2년 동안 특성평가 및 특성검정을 통해 ‘Dream Song’을 육성하였다. ‘Dream Song’의 초형은 직립형이고, 잎 모양은 피침형, 소화는 꽃잎수가 많고 암술이 2개인 백색겹꽃으로 꽃잎은 도란형, 꽃잎 끝 모양은 약간 둥근형, 꽃받침 모양은 컵형인 ‘Dream Song’ 고유의 특성을 가진다. 또한 소화의 일시개화성이 우수하고 절화수명이 매우 길며, 분지각이 작고 흰가루병에 강하고 총체벌레와 잎굴파리 등 충해에도 강해 재배적 가치가 높은 특성을 가진다. 준고냉지 여름절화 작형에서 ‘Dream Song’ 개화는 ‘Bristol Fairy’보다 17일 늦고 절간장과 화경장이 길었으며, 측지 분화가 많고 줄기가 굵었다. 또한 소화가 크고 야간 기온 22℃, 7일 이상의 고온조건에서도 기형화 발생이 없었다. ‘Dream Song’ is a cultivar of Gypsophila paniculata developed by the Jeollabuk-do Agricultural Research & Extension Services in 2010 for cut-flower production. This hybrid was bred from 121 seedlings collected from an open-pollinated population of ‘Gyp06-11’. It has novel morphological characteristics of upright plant type, lanceolate leaves, double florets with a few bright white-colored petals of obovate shape, truncate petal tips, and cup-shaped calyces. Furthermore ‘Dream Song’ has desirable cultivation characteristics including narrow branching angle, and moderate resistance to powdery mildew, thrips and leaf miners. Moreover it produces more primary branches, and longer internodes and flower stalks than reference cultivar ‘Bristol Fairy’ during summer cultivation in a subalpine area (500 m over the sea level). Flowering in ‘Dream Song’ is delayed by about 17 days as compared to ‘Bristol Fairy’. ‘Dream Song’ produces normal flowers with 2 pistils and an average of 10.4 stamens, with fewer malformed flowers than ‘Bristol Fairy’.

      • KCI등재

        Evaluation of the Efficacy and Safety of DA-9601 versus Its New Formulation, DA-5204, in Patients with Gastritis: Phase III, Randomized, Double-Blind, Non-Inferiority Study

        Choi, Yoon Jin,Lee, Dong Ho,Choi, Myung-Gyu,Lee, Sung Joon,Kim, Sung Kook,Song, Geun Am,Rhee, Poong-Lyul,Jung, Hwoon-Yong,Kang, Dae-Hwan,Lee, Yong Chan,Lee, Si Hyung,Choi, Suck Chei,Shim, Ki-Nam,Seol, KOREAN ACADEMY OF MEDICAL SCIENCE 2017 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.32 No.11

        <P>This study compared the efficacy of DA-9601 (Dong-A ST Co., Seoul, Korea) and its new formulation, DA-5204 (Dong-A ST Co.), for treating erosive gastritis. This phase III, randomized, multicenter, double-blind, non-inferiority trial randomly assigned 434 patients with endoscopically proven gastric mucosal erosions into two groups: DA-9601 3 times daily or DA-5,204 twice daily for 2 weeks. The final analysis included 421 patients (DA-5204, 209; DA-9601, 212). The primary endpoint (rate of effective gastric erosion healing) and secondary endpoints (cure rate of endoscopic erosion and gastrointestinal [GI] symptom relief) were assessed using endoscopy after the treatment. Drug-related adverse events (AEs), including GI symptoms, were also compared. At week 2, gastric healing rates with DA-5204 and DA-9601 were 42.1% (88/209) and 42.5% (90/212), respectively. The difference between the groups was −0.4% (95% confidence interval, −9.8% to 9.1%), which was above the non-inferiority margin of −14%. The cure rate of gastric erosion in both groups was 37.3%. The improvement rates of GI symptoms with DA-5204 and DA-9601 were 40.4% and 40.8%, respectively. There were no statistically significant differences between the two groups in both secondary endpoints. AEs were reported in 18 (8.4%) patients in the DA-5204 group and 19 (8.8%) in the DA-9601 group. Rates of AE were not different between the two groups. No serious AE or adverse drug reaction (ADR) occurred. These results demonstrate the non-inferiority of DA-5204 compared to DA-9601. DA-5204 is as effective as DA-9601 in the treatment of erosive gastritis. Registered randomized clinical trial at ClinicalTrials.gov (NCT02282670)</P>

      • KCI등재

        한국어 판 구조화 임상면담도구 개발 : 신뢰도 연구

        한오수,안준호,송선희,조맹제,김장규,배재남,조성진,정범수,서동우,함봉진,이동우,박종익,홍진표 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

        연구목적: 정신장애의 정확한 진단과 평가는 임상에서뿐만 아니라 신뢰성 있는 연구를 위해서도 매우 중요하다. Structured Clinical Interview for DSM-IV(SCID)는 임상전문가들이 사용하는 진단도구로서, 비교적 짧은 시간에 정확한 진단을 내릴 수 있다. 본 연구는 한국어판SCID를 개발하고 그 신뢰도를 평가하기 위해 수행되었다. 방법: 국문학자가 포함된 번역위원회를 통하여 연구용판 SCID를 번역한 후, 정신과 의사 2인과 임상심리학자 1인에게 한국어판SCID 실시방법을 교육시킨 뒤 한국어판SCID를 이용한 면담의 평가자간 신뢰도 (interrater reliability)를 검증하였다. 면담 대상은 1999년 2월에서 3월까지 2개 병원 정신과에 치료중인 환자 90명(남:41명, 여:29명)이었다. 결과: 현재 장애(current disorder) 평가에서 주요 우울장애, 기분부전장애, 정신분열병, 알코올 남용 및 의존, 기타 물질 남용 또는 의존, 여러 불안장애들 및 섭식장애 등과 같은 대부분 장애의 kappa값은 .70이상으로 매우 높았다. 그 이외의 양극성 장애, 망상장애, 광장공포증, 감별 불능 신체화 장애 및 건강염려증의 kappa값도 .69에서 .40사이로 수용할 수 있는 정도였다. 평생 장애(lifetime disorder)에서는 양극성 장애(k=.69)와 감별 불능 신체화장애(k=.59)를 제외한 다른 모든 장애의 kappa값이 .70이상이었다. K-SCID 면담시 Ⅰ축 질환에 대하여 흔하게 다중 진단이 내려졌으며, 평균 진단 수는 1.5∼1.7개로 나타났다. 결론: 한국어판 SCID는 신뢰도가 높은 진단도구로 생각되며, 향후 정신질환의 정확한 진단과 임상연구에 유용하게 사용될 수 있다. Objectives: Accurate diagnosis and assessment for psychiatric disorders is crucial for research, as well as for clinical practice. Structured Clinical Interview for DSM-Ⅳ(SCID-RV) is a less time-consumimg and more accurate structured diagnostic interview form. It can be used by clinical professions and is known for a reliable diagnostic tool. Present study was conducted to develop Korean version of SCID-RV and to test the inter-rater reliability. Methods: The authors have translated original SCID-RV into Korean, and revised in parallel with sociocultural background of Korea. Ninety patients from two psychiatric hospitals, both outpatient and inpatient, were interviewed and rated independently by three raters. Results: The kappa coefficients for most of illnesses, such as major depressive disorder, dysthymia, schizophrenia, alcohol abuse and dependency, anxiety disorder and eating disorder were excellent(>0.70) in the evaluation of current disorders. And the kappa coefficients for bipolar disorder, delusional disorder, agoraphobia, undifferentiated somatoform disorder, and hypochondriasis were acceptable(>0.40) in the evaluation of current disorders. In the evalua-tion of lifetime disorders, the concordant rates of all the diagnoses except bipolar disorder and undifferentiated somatoform disorder were excellent. Lack of hierarchy in DSM-Ⅳ allows for multiple Axis I diagnoses. Mean numbers of Axis I diagnoses per subject assigned by the three raters were 1.5-1.7. Conclusions: Our findings confirm that SCID-RV yields highly reliable diagnoses. SCID-RV is recommended for accurate diagnosis in clinical practice and research on psychiatric disorders.

      • 트레드밀 운동시 흡기근 테이핑이 폐활량에 미치는 영향

        김민지,신수영,송월섭,조수진,최동락,황미진,황진규,박진현,김경,Dennis W. Fell 대구대학교 특수교육재활과학연구소 2011 再活科學硏究 Vol.29 No.1

        이 연구는 트레드밀 운동과 키네시오 테이핑의 효과에 따른 폐활량의 변화를 알아보기 위해 26명의 비흡연자가 참가하였으며 키네시오 테이핑을 적용하지 않은 그룹과 키네시오 테이핑을 적용한 두 그룹으로 무작위로 배정하고 각 군들을 주 3회 6주간의 트레드밀 훈련을 실시하였다. 실험 전과 후, 스파이로미터를 사용하여 키네시오 테이핑의 적용 따른 폐활량 변화 효과를 측정하였다. 이 연구의 결과를 종합해보면 키네시오 테이핑을 적용 그룹에서 적용하지 않은 그룹에 비해 FVC, FEV1에서 유의한 증가를 보였다. 이러한 결과는 건강한 성인에서 키네시오 테이핑을 적용한 경우 키네시오 테이핑을 적용하지 않고 트레드밀 운동을 한 경우보다 폐활량의 향상에 효과적이라고 생각되어진다. The purpose of this study was to investigate the variation of vital capacity(VC) according to the effects of kinesio taping with treadmill exercise. Twenty-six non-smokers were participated in this research and these subjects were randomly assigned into two groups. To measure the VC variation effects of kinesio taping, spirometer was used. The collected data were analyzed statistically by using a paired Mauchly test and repeated measure ANOVA. The results of this study were as follows; A group: treadmill with kinesio taping B group: treadmill without kinesio taping. Between A and B, there were significant differences. In the case of A group, there was 11.66% increase of VC, during 3 weeks experiment(p<.01). In the case of B group, there were significant differences, 3.35% increase of VC, during 3 weeks taping intervention(p<.01). After 6 weeks experiment, the improvement of VC shown a significant difference with intergroup (p<.05). From this result, it was revealed that treadmill exercise with kinesio taping was effective to improve VC to healthy adult than treadmill exercise without kinesio taping.

      • 都市 下水슬러지의 堆肥化에 關한 硏究

        宋濟天,柳明辰,金東玟 동아대학교 환경문제연구소 1986 硏究報告 Vol.9 No.3

        Composting may be defined as a biochemical process in which microorganisms break down and convert solid organic matters into stable, humus like end products. The composting of municipal wastewater sludge has become an accepted technology as a means of sludge stabilization and resource recovery in recent years. Investigated in this study were the compostability of municipal sludge without the use of bulking agents, e.g., wood chips, tree barks, sow-dusts and rice-hulls ; relevant, influencing factors such as moisture contents, pH values, aeration rates, and volatile solid contents ; and process reaction rates. The sample sludges, obtained from Seoul Cheongye Sewage Treatment plant, were those digested and dewatered by mechanical means with the aid of lime and ferric chloride. The pH values, moisture contents, voltile solid contents and C/N ratios of the sample sludge ranged 10 to 12, 60 to 70%, 55 to 55% and 8 to 12, respectively. In this study, three, 35-liter reactors were used; the reactors were operated on batch basis for the duration of 8 to 12days. In order to maintain aerobic conditions and expect air drying effects, air was supplied to each reactor in the rates of 50-300 ℓ/㎥, main in the first half of experiments and fixed to 120ℓ/㎥. min in the second half. The mixture was mixed completely once a day by mechanical agitator. The results of this study follow; 1. The municipal sludge can be composted without the use of bulking agents. 2. The composting of the sole sludge without any additives can be carried out in reduced reaction periods 1 to 2 weeks. 3. The compost sludge can be used as both, the soil conditioner and low-nutrient fertilizer. It contained 35 to 40% moisture, 35 to 45% valatile solids, 1.9 to 2.2% nitrogen, 2.1 to 2.5% phosphorus and 0.18 to 0.22% potassium, and was 7.5 to 8.0 in pH values and 8 to 10 in C/N ratios. 4. The optimum pH values, aeration rates, and moisture contents were 7.5 to 8, approximately 120ℓ/㎥.min and 55 to 60%, respectively.

      • 어린 개에서 발생한 선천성 특발성 거대도식증 1례

        서동규,박형진,송근호,서경원 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        Three-month-old, intact male, weighting 2.6 kg. Dachshund dog visited to the Veterinary Medical Teaching Hospotal of Chungnam National University with history of regurgitation. Result of blood analysis was in the normal range. On the radiographic examination, diffuse esophageal dilatation was observed. On the esophagram, esophageal dysmotility was observed. Acetylcholine receptor antibody titer was in the normal range. On the endoscopy, esophagitis was observed. Diagnosis was congenital idiopathic megaesophagus. This is the case report of congenital idiopathic megaesophagus.

      • 돈육의 지방산과 아미노산 조성 및 관능 특성에 미치는 미생물제제 및 고구마 사일리지 급여 효과

        진상근,김일석,송영민,박기훈,정기종,김동훈,이정일 진주산업대학교 산업과학기술연구소 2006 산업과학기술연구소보 Vol.- No.13

        3원교잡종(LY×D) 돼지를 이용하여, 60일 동안 미생물제제 K를 3% 급여한 A 처리구와 O를 3% 급여한 B 처리구 및 가고시마흑돼지에게 10% 고구마 사일리지를 급여한 C 처리구로 각 처리구별로 30두씩 공시하여 사양 시험 후 돈육의 지방산, 아미노산 조성 및 관능적 특성에 미치는 효과를 분석하였다. 가열육의 관능검사에서는 B 처리구가 다른 처리구들에 비하여 유의적으로 높은 값을 보였다(p<0.05). 처리구 간에 지방산 조성 변화를 보면 palmitic과 palmitoleic acid 함량은 C 처리구가 다른 처리구들에 비하여 유의적으로 높았다(p<0.05). Aspartic, threonine, serine, glutamic, isoleucine과 phenyl alanine 함량은 C 처리구가 다른 처리구들에 비하여 유의적으로 높았다(p<0.05). Proline, alanine, cystine, valine, methionine, leucine과 histidine 함량은 B 처리구가 다른 두 처리구들에 비하여 유의적으로 낮은 아미노산 함량을 보였다(p<0.05). A total of 90 pigs were used to investigate the effect of feeding microbes and sweet potato silage on physico-chemical characteristics of pork loin. About 60 kg pigs were randomly alloted into one of three experimental diet groups (A: Supplemented with 3% K microbe; B: Supplemented with 3% O microbe; C: Supplemented with 10% sweet potato silage). Pigs were slaughtered at approximately 110 kg live weight and fatty acid, amino acid and sensory characteristics were measured in pork loin. In cooked meat, sensory evaluation was significantly higher in B compared to other treatments (p<0.05). The palmitic and palmitoleic acid content of C treatment were significantly higher than those of other treatments (p<0.05). In amino acid composition, aspartic acid, threonine, serine, glutamic acid, isoleucine and phenyl alanine level were significantly higher in C treatment compared to other treatments (p<0.05).

      • KCI등재
      • 유산소 운동 능력의 차이가 점증최대운동부하 후 피로회복과정에 미치는 영향

        송영주,권대근,성동진,황정윤,박천조,김춘우 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

        This study was conducted to investigate the effects of aerobic capacity on blood lactate changes after supramaximal progressive loaded exercise. The subjects were divided into Handball players(HB, n=6)group and Control(CT, n=6)group. All subjects exercised according to the protocol by bicycle erogometer. Blood lactate concentration was also measured during the test time. The RER values of CT group were relatively higher than that of HB group. In particular, the RER values of HR group at exercise 8 & 12min were significantly lower than that of CT group(P<0.05). The blood lactate concentration of HB group was significantly lower than that of CT group at 12min during the exercise(P<0.05). During the recovery times the blood lactate concentration of HB group were significantly lower than that of CT group. In addition, blood lactate clearance of HB group was also higher than that of CT group during the recovery time. From these results, it was suggested that lactate clearance during the supramaximal exercise may be affected by the level of endurance exercise performance.

      • 개에서 발생한 파열된 전이성 비장 혈관육종 1례

        서동규,박형진,송근호,서경원 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        Twelve-year-old, catrated male, weighting 8 kg, Miniature Schnauzer dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with history of depression. Result of blood analysis revealed anemia, thrombocytopenia, azotemia, elevated ALP, ALT and CK. On the radiographic examination, splenomegaly and loss of abdominal serosal detail were observed. Abdominal ultrasonography showed rounded mass of spleen and liver, ascites were observed. Splenectomy was performed and found that splentic tail had been ruptured and two samples from nodules on liver were obtained for histopathology. The result of biopsy revealed that hemangiosarcoma of spleen metastasized to the liver. Carboplatin was chosen as the patient had congestive heart failture. During chemotherapy hemangiosarcoma was metastasized into peritoneum and abdominal cavity. Intraperitoneal chemotherapy was preceded at this moment. After 99 days of initial visit, patient was euthanized due to severe anemia and thrombocytopenia.

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