임신중의 급성 신우신염에 대한 고찰

최규홍,김희진,이기동,박상철,최영주 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.6

1985년 1월 1일부터 1989년 12월 31일까지 청구성심병원 산부인과에 입원하였던 임산모 4,851명에 대하여 임산중과 분만후 6주이내에 급성 신우신염으로 판명된 53예를 대상으로 다음과 같은 임상적 연구결과를 얻었다. 1. 동 기간중 산부인과를 방문한 4,851명의 산모중에서 53예가 급성 신우신염으로 입원하여 그 빈도가 1.09%를 보였다. 2. 임신기간별로 볼 때 그 빈도가 임신중에는 임신중기가 35.8%로 가장 많았고, 분만후에는 26.4%를 보여 분만후보다 분만전이 발병율이 높았다. 3. 가장 발생이 많은 연령층은 주로 임신적령기 (25∼29세)때로, 45.3%를 보였으며 평균발생연령은 28세였다. 출산경력상으로는 초산부에서 53명중 33예(62.3%)로 가장 많았다. 4. 급성 신우신염을 유발시키는 기왕력을 보면, 원인불명이 22예(41.5%)이고 과거 요로감염이 있었던 환자가 총 15예(28.3%)와 도뇨가 9예(17.0%)순이였다. 5. 임상증상중 가장 흔한 것은 고열 오한이 50예(41.0%)였으며, 그 다음으로 혈복부동통과 요통이 46예(37.7%)였으며, 특히 우측이 좌측에 비하여 3배정도 높았다. 35예에서 (66.0%) 38℃이상의 고열을 동반하였으며, 대부분이 입원후 48시간만에 고열의 소실(23예, 43.4%)를 보였다. 6. 증상이 시작되어 입원하기까지 기간으로는 1주이내가 23예(43.4%)로 가장 많았으며, 2주이내가 19예(35.8%)로 나타났고, 2주이상 지속된 예(11예, 20.8%)도 있었다. 7. 요검사소견에서 백혈구수가 5/HPF이상 보인자가 53명중 41예(71.5%)로 나타났으며, 이 중에서 백혈구수가 31/HPF이상 보인 경우가 25예(47.2%)로 가장 많았고, 정상을 보인 경우도 12예(22.6%)였다. 혈액소견상에서도 백혈구수가 8,000/㎣이상 보인 경우는 42예(79.2%)로 나타났다. 8. 요세군 배양검사상 그람음성균이 양성균에 비하여 26예(63.4%)로 가장 많았는데, 이 중에서 대장균이 22예(53.7%)로 높았고, 그 다음이 포도상구균이 4예(9.8%)였다. 혈액배양에서도 역시 대장균이 3예(42.9%)였다. 9. 약제에 대한 감수성소견에서는 대장균이 amikacin(78.3%)에 감수성이 높았으며 포도상구균은 ampicillin에 (77.6%), pseudomonas은 gentamycin에 (76.9%) 연쇄상구균은 erythromycin에(75.5%) 감수성이 있었다. 10. 태아에 미치는 영향으로는 신우신염으로 입원한 산모와 조산관계는 큰 차이를 발견할 수가 없었다(8.5% : 9.5%). Acute pyelonephritis is the most frequent complication involving the urinary tract, as well as the most frequent medical cause of hospitalization, during the course of pregnancy. And associated with risk to the mother and fetus. We have retrospectively evaluated 53 cases among 4,851 pregnant women following an acute episode of pyelonephritis during pregnancy admitted at the Chung Goo Sung Shim Hospital during the 5 years period from Jan. 1, 1985 to Dec. 31, 1989. The incidence was 53 cases out of 4,851 gestational women cases during the same period and the rate was 1.09%. Acute pyelonephritis occurred usually during the second trimester and third trimester. It was most common in second trimester (35.8%) and postpartum (26.4%). The most prevalent age distribution was seen in the age grup of 25 to 29 years. The average age was 28 years old. And is commoner in primiparas than in multiparas, that is does occur in about 62.3% of primiparas, rising to about 37.5% in multiparas. History of previous factors were unknown in 22 cases (41.5%) of all cases, followed previous urinary tract infection in 15 cases (28.3%) and were due to previous catheterization in 9 cases (17.0%). As to the initial chief complaints, high fever and chils was found in 50 cases (41.0%) and flank pain or lumbago was 46 cases (37.7%). The right flank tenderness was affected 3 times (32 cases) more than left (9 cases), and 12 cases were bilateral. The febrile condition was 38℃ or more in 41 cases (71.5%) of the patients, 23 cases were completely afebrile within 48 hours after the onset of therapy. On duration of symptoms and signs until admission, 23 cases (43.4%) of all cases were less than 1 week but 11 cases (20.8%) were more than 2 weeks. In the microscopic urinalysis, white blood cell count per the high power field ( 5/HpF) was measured in 41 cases or 71.5%. Of these 41 cases, 25 patients (47.2%) were identified the leukocytosis with more than 31/HpF of ㅉ but normal urine was seen in 12 cases (22.6%).And the serum leukocytosis(8,000/mm3)was found in 42 cases (79.2%). The most frequently associated Gram negative organisms(63.4%)more than positive organisms(17.1%)in the urine at colony counts of $gt; 105 per milliliter.The most predominant microorganisms isolated was coliform and of these Wscherichia coli was the most common organisms(53.7%)and the rest was staphylococci organisms.And the Escherichia organisms was cultured from the blood of 3 cases(42.9%)of the patients. In sensitivities for this microorganisms, Escherichia coli was highly sensitive to Amikecin(78.3%),Ampicillin(74.9%).And the staphylococci was highly sensitive to Ampicillin(77.6%), Clindamycin(75.8%). In correlation between the pregnant women with pyelonephritis and the pregnant women without phelonephritis for prematurity there was no relationship between the two(8.:9.5%).And there was no spontaneous abortion and neonatal anomaly in this study.

BELLE TOF 검출기의 특성 연구

남지우,김동욱,배미영,박강순,김정현,노상률,최영일,김희종,장동욱,최소명,권영준,Hikita, S.,Yu, C.,Yoshimura, Y.,Kichimi, H. 성균관대학교 기초과학연구소 1998 論文集 Vol.49 No.-

We investigated the properties of BELLE Time Of Flight(TOF) counter using the data taken in Jan 98 beam test at Pi2 beam line at KEK 12 GeV proton synchrotron. Charge distributions from readout PMT were analysed in comparison with dE/dx distributions predicted by GEANT full simulation. Experimental setup of the beam test is described, then procedures of data analysis, Monte Carlo simulation and analysis results are also described.

Acute and Genetic Toxicities of Recombinant Anticoagulant Hirudine

YJ Kim,OS Kwon,YS Song,HT Kim,YJ Choi,MK Kim,JC Ryu 대한약학회 1999 大韓藥學會 總會 및 學術大會 Vol.48 No.-

Genome-wide gene expression analysis in the fetal trisomy 21 placenta

( Yj Han ),( Ej Choi ),( Jm Lee ),( Dw Kwak ),( Sw Lee ),( Mh Kim ),( Jh Chung ),( Hk Ahn ),( Js Choi ),( Jy Han ),( My Kim ),( Jh Lim ),( Hyun Mee Ryu ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

목적: To gain new insight of gene expression into the pathogenesis of trisomy 21 (T21) placenta, we performed whole human genome expression analysis in placenta tissue (normal and T21) samples. 방법: We profiled whole human genome expression of placenta samples from normal and T21 fetuses using GeneChip Human Genome U133 plus 2.0 array and predicted the functions of differentially expressed genes using bioinformatics tools. 결과: One hundred-ten genes were significantly differentially expressed in the T21 placenta compared with the normal placenta (33 down-regulated and 77 up-regulated). Among them, some genes were significantly associated with focal adhesion, Alzheimer's disease, and Parkinson's disease pathway. The down-regulated genes in the T21 placenta were distributed on various chromosomes. The down-regulated genes were significantly associated with cystitis, metaplasia, pathologic neovascularization, airway obstruction, and diabetes mellitus type 2. None of down-regulated genes were on chromosome 21 causing T21, whereas over half (59.7%) of up-regulated genes were located on chromosome 21. The up-regulated genes were significantly associated with T21 and T21-related disorders, such as mental retardation, neurobehavioral manifestations, and congenital abnormalities. 결론: Our findings provide a broad overview of whole human genome expression in the placentas of fetuses with T21 and could contribute to future research efforts concerning genes involvement in disease pathogenesis.

Laparoscopic Approach for Intraabdominal Lymphatic Malformation in Children

Yj Choi,Dy Kim,Jm Namgoong,SC Kim,HH Kwon 대한외과학회 2018 대한외과학회 학술대회 초록집 Vol.2018 No.11

선천성 부신성 증후군

최영중(YJ Choi),최영균(YK Choi),이영혜(YH Lee),한의정(EJ Han) 대한산부인과학회 1977 Obstetrics & Gynecology Science Vol.20 No.1

최근 실질적으로 나타난 선천성 부신피질증식증에 의한 여성반음양을 경험하기에 문헌과함께 보고하는 바이다. Patient. Kim. S.R, was examined together with her younger sister (kim. J.R) because of enlargement of clitoris, fusion of labioscrotal folds and musculine configuration. The child has been brought up as a girl. The patient developed in a way similar to her younger sister. Sex chromatin in oral mucosa smear: positive. Chromosome study: cytogenenetically normal 46/XY, female. Baseline urinary 17 KS was 37.3㎎/24hours. After three day`s treatment with dexamethasone, the output oh 17KS was 4. 55㎎/24 hours. Retroperitoneal pneumogram including tomography revealed to marked enlargement bilateral adrenal gland. Vaginogram showed uterus measured 3×2 ㎝ and distended vagina 6㎝ in length. Two case of female pseudohermaphroditism with virilization delveloped in sisters is presented a brief review of the concerned literatures.

고콜레스테롤혈증 환자에 대한 아토바스타틴의 효과와 안전성을 검토하기 위한 다기관 공동 임상 연구

배종화,최경훈,전재은,박의현,김권배,김기식,이재우,이원로,박정의,최윤식,권영주,강정채,김종준,문용,홍순표,김태호,김영조,심봉섭,박승정,정진원,이건주,최규보,임종윤,이방헌 대한순환기학회 2001 Korean Circulation Journal Vol.31 No.4

Testicular feminization syndrome 1례

최영균(YK Choi),이영혜(YH Lee),최영중(YJ Choi),정신호(SH Chung) 대한산부인과학회 1978 Obstetrics & Gynecology Science Vol.21 No.1

저자들은 최근 전주예수병원 산부인과에서 testicular feminization syndrome 1예를 경험하였기에 간단한 문헌적 고찰과 함께 그 증례를 보고하는 바이다. Testicular Feminization is a hereditary syndrome characterized by in dividuals with testes who present a female phenotype. We presented a case of testicular feminization syndrome with nearly normal size of blind vagina associated with bilateral inguinal gonads, who received laparatomy with resection of tsetes, with brief review of literatures.

독립형 10kW ESS의 레독스 플로우 배터리 초기 구동 전원 제어

최중묵(JM Choi),송용희(YH Song),최은석(ES Choi),은종목(JM Eun),이영진(YJ Lee),한동화(DH Han),조영훈(YH Cho),최규하(GH Choe) 전력전자학회 2013 전력전자학술대회 논문집 Vol.2013 No.7

안산시 주거지역을 중심으로 한 환경대기 중 휘발성 유기화합물과 황계열 성분의 온라인 연속측정 연구

김기현,주도원,최여진,홍윤정,사재환,박종호,전의찬,최청렬,구윤서,Kim K.-H,Ju DW,Choi YJ,Hong YJ,Sa JH,Park JH,Jeon EC,Choi CR,Koo YS 한국대기환경학회 2005 한국대기환경학회지 Vol.21 No.1

In this study, the concentrations of major odorous compounds including reduced sulfur compounds (OMS, CS$_2$, and DMDS) and aromatic VOC (benzene, toluene, xylene, etc.) were measured continuously using an on-line GC analytical system. Our measurements were made from a residential area of Ansan sity during about two week period of October, 2004. The highest mean concentrations of Sand VOC were found as 56.9 pbb of DMS and 21.7 ppb of toluene, respectively. The results of this study generally show that the pollution levels for both types of chemicals are significant relative to previous measurement results reported from comparable sites, if the results are compared simply in terms of the magnitude of the measured concentration data. Moreover, when the relative importance of different compounds is compared in terms of the odor strength, it indicated that the contribution of reduced S compounds may be much more important than that of VOC in the study area.