여성 외음부에 발생한 선상 편평상피세포암종

김창옥,양기화,강석진,이안희,김병기,김선무 대한병리학회 1991 Journal of Pathology and Translational Medicine Vol.25 No.1

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

심폐소생술의 순환회복 예측인자로서 호기말 이산화탄소 분압의 유용성 및 의의 : 각 심정지 원인에 따른 분석

어은경,안기옥,김정연,전영진,정구영 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: In recent years, there has been increasing interest in the use of capnometry, the noninvasive, continuous measurement of end-tidal carbon dioxide(ETCO2) in expired air during CPR. The purpose of this study is to determine the significance of ETCO2 monitoring according to immediate cause of arrest during CPR as a prognostic indicator of successful resuscitation and survival. Methods: A prospective, clinical study was performed from May 1997 to December 2000 at the Department of Emergency Medicine, Ewha Womans University Mokdong Hospital. The study included 220 patients(231cases). All patients were immediately connected to a mainstream capnometer sensor between the tube and the bag after endotracheal intubation using an infrared capnometer. Results: The 107 patients(46.3%) with return of spontaneous circulation(ROSC) had higher maximal ETCO2 during CPR than the 113 patients without ROSC(31.0±19.4 vs 11.7±9.4 mmHg, P=0.000). The ETCO2 was not significantly different in relation to age, initial rhythm, and survival time after ROSC, but there was a significant difference in the immediate cause of arrest in the ROSC group(respiratory arrest: 40.2±23.5 mmHg, P=0.000). In case of cardiac arrest due to trauma, maximal ETCO2 was not significant in the ROSC group compared with the non-ROSC group(18.2±16.6 vs 10.8±7.5 mmHg, P=0.208). When maximal ETCO2 was less than 10 mmHg, we observed a sensitivity of 94.4% and a specificity of 39.5% in predicting ROSC. There were 6 patients with ROSC even though the maximal ETCO2 was less than 10 mmHg. Conclusion: Continuous ETCO2 monitoring during CPR may be noninvasive and valuable predictor of successful resuscitation and survival from cardiac arrest. However, ETCO2 should not be used as a single indicator for either cardiac arrest due to trauma or withdrawal of CPR.

알코올 금단 발작 환자에서 진전 섬망 예방에 대한 Nimodipine과 Chlordiazepoxide의 효과 비교

정두신,양광익,이보람,방차옥,이태경,성기범,안무영,박형국 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background & objectives : An increase of calcium influx during alcohol withdrawal state may contribute to neuronal hyperexitability, which cause delirium tremens(DT). Some investigators have found calcium channel blockers effects in prevention of DT in experimental animals. Therefore we evaluated the preventive effects of calcium channel blocker(nimodipine) and benzodiazepine(chlordiazepoxide) on the development of DT in alcohol withdrawal seizure(AWS) patients. Method : A total 59 patients with AWS were divided into three groups according to the management nimodipine-treated, chlordiazepoxide-treated, and control(no specific medication) groups. We compared the incidence rates of DT in the three groups. Results : Total incidence rate of DT was 30.5%(18 of 59 patients). There were 6 DTs of 18 patients(33.5%) in nimodipine-treated group, 4 of 21 patients(22.5%) in chlordiazpoxide-treated group, and 8 of 20 patients(44.0%) in control. Conclusion : The control group(44.0%) showed the highest incidence rate of DT. And nimodipine-treated(33.5%) and chlordiazepoxide-treated group(22.5%) were followed. However, this result failed to demonstrated statistically significant differences due to small numbers size.

Cell proliferation and neuroblast differentiation in the rat dentate gyrus after intrathecal treatment with adipose-derived mesenchymal stem cells.

Choi, Jung Hoon,Chung, Jin Young,Yoo, Dae Young,Hwang, In Koo,Yoo, Ki-Yeon,Lee, Choong Hyun,Yan, Bing Chun,Ahn, Jin Ok,Youn, Hwa Young,Won, Moo-Ho Kluwer Academic/Plenum Publishers 2011 Cellular and molecular neurobiology Vol.31 No.8

<P>Mesenchymal stem cells (MSC) have emerged as a new therapeutic tool for a number of clinical applications, because they have multipotency and paracrine effects via various factors. In the present study, we investigated the effects of adipose-derived MSC (Ad-MSC) transplantation via intrathecal injection through the cisterna magna on cell proliferation and differentiation of endogenous stem cells in the hippocampal dentate gyrus (DG) using Ki-67 (a marker for proliferating cells), and doublecortin (DCX, a marker for neuroblasts). The transplanted Ad-MSC were detected in the meninges, not in the hippocampal parenchyma. However, the number of Ki-67-immunoreactive cells was significantly increased by 83% in the DG 2 days after single Ad-MSC injection, and by 67% at 23 days after repeated Ad-MSC treatment compared with that in the vehicle-treated group after Ad-MSC transplantation. On the other hand, the number of DCX-immunoreactive cells in the DG was not changed at 2 days after single Ad-MSC injection; however, it was significantly increased by 62% 9 days after single Ad-MSC injection. At 23 days after repeated Ad-MSC application, the number of DCX-immunoreactive cells was much more increased (223% of the vehicle-treated group). At this time point, DCX protein levels were also significantly increased compared with those in the vehicle-treated group. These results suggest that the intrathecal injection of Ad-MSC could enhance endogenous cell proliferation, and the repeated Ad-MSC injection could be more efficient for an enhancement of endogenous cell proliferation and differentiation in the brain.</P>

ICECI (International Classification of External Causes of Injuries)를 이용한 중증 소아외상의 분류

안기옥 ( Ki Ok Ahn ),김재은 ( Jae Eun Kim ),장혜영 ( Hye Young Jang ),정구영 ( Koo Young Jung ) 대한외상학회 2006 大韓外傷學會誌 Vol.19 No.1

Purpose: Injury is a leading cause of morbidity and mortality for children. As an injury prevention measure, the differences in external causes of severe pediatric injuries based on ICECI were analyzed according to age groups. Methods: A retrospective study was performed for pediatric patients under 15 years of age, who had been admitted to the emergency department with severe injuries from January 1998 to December 2004. The external causes of injury were investigated according to the ICECI: intent, mechanisms, places of occurrence, objects/substances producing injury, and related activities. The patients were divided into four groups based on age: infant (<0 year), toddler (1~4 years), preschool age (5~8 years), and school age (9~15 years). Results: The injury mechanisms, the places of occurrence and the related objects/substances vary with the age groups. The most common subtype of traffic accidents was pedestrian injury in pre-school age group. Falls most frequently occurred in the toddler group. But falls from a height of less than l meter height (6 patients) occurred only in the infant group. The most common place of occurrence in the infant group was the home, and that of other groups was the road. The related objects/substances for falls, for example, household furnitures and playground equipment depended on the age group. Conclusion: The age-group specific characteristics of severe pediatric injury were analyzed successfully through the ICECI. Therefore, when establishing a plan for the prevention of pediatric injury, consideration must be given to the differences in the external causes of injuries according to age group. (K Korean Soc Traumatol 2006;19:1-7)

초등 방과 후 학교 체육프로그램의 현장 적용 가능성 탐색

안양옥 ( Yang Ok Ahn ),김기철 ( Ki Chul Kim ),박상봉 ( Sang Bong Park ) 서울敎育大學校 初等敎育硏究所 2010 한국초등교육 Vol.20 No.2

본 연구는 안양옥(2007)이 개발한 방과 후 체육활동 프로그램을 현장에 적용하여 프로그램의 효용성의 확인과 확산가능성의 탐색에 그 목적이 있다. 이를 위해 3개의 초등학교를 목적 표집하여 12주차 프로그램을 적용하고 참여관찰, 학생, 학부모, 교사, 장학사와의 심층면담 등을 통해 자료를 수집 분석하였다. 연구결과 방과 후 체육활동 프로그램은 불충분한 정과체육의 보충기능, 생활체육으로의 연계 역할, 신체활동 참여에 대한 인식 전환 유도, ‘교육격차해소’를 통한 교육복지의 구현, 올바른 체육문화입문에 기여와 같은 효용성 및 교육적 가치가 있음이 드러났고, 방과 후 프로그램의 지속적 확산을 위해서는 프로그램의 다양화 모색, 대교경기와 연계된 활동의 지속운영방안 모색, 사교육 체육활동과의 경쟁력 강화, 방과 후 체육활동 프로그램의 효율적 운영을 위한 제반 환경 개선 등이 요구되었다. This study aims at exploring the applicability and effectiveness of after school physical programs Yangok Ahn(2009) developed. To accomplish this purpose, 3 elementary schools were selected and the programs were applied. To collect the data and analyze, participant observation, in-depth interview with students, their parents, teachers and supervisors were used. Findings of this study were as follows: Firstly, after school physical programs had effects on supplement of physical activities lacking in P.E. class, played a role of the motive power to the sports for all, the transfer of positive recognition in participation, the to -uchstone as the realization of education welfare through reducing educational gap. Secondly, to spread after school physical programs, diversity of programs, continuous operation through the competition with other schools, to strengthen the competitiveness with private physical programs, the improvement of system supporting efficient management.

초등교사의 게임에 관한 개념적 지식 분석

안양옥(Yang Ok Ahn),신기철(Ki Cheol Shin),김기철(Ki Cheol Kim) 한국스포츠교육학회 2005 한국스포츠교육학회지 Vol.12 No.2

The effect of ovariectomy and 17-beta estradiol on the change of histology and estrogen receptor of bladder in female bladder outlet obstruction rat model

( Ki Hoon Ahn ),( Hyun Tae Park ),( Chul Hwan Kim ),( Seung Ok Hong ),( Tak Kim ),( Young Tae Kim ),( Sun Haeng Kim ) 대한산부인과학회 2011 대한산부인과학회 학술대회 Vol.97 No.-

심폐소생술 후 고체온증이 신경학적 결과에 미치는 영향

안기옥,이광정,어은경,정구영 대한응급의학회 2003 대한응급의학회지 Vol.14 No.1

Purpose: This study is to clarify the clinical characteristics of hyperthermia and to evaluate the correlation between hyperthermia and neurologic outcome after successful cardiopulmonary resuscitation (CPR). Methods: This retrospective study was performed from Aug. 1995 to Dec. 2001 at the Ewha Womans University Mokdong Hospital. We reviewed the medical records of 41 adult patients who survived for longer than 72 h after successful CPR. The patients were divided into two groups: favorable neurologic outcome group (n=l7) and unfavorable neurologic outcome group (n=24). The hyperthermic group was composed of patients whose highest body temperature had been more than 38˚C. In the hyperthermic group, we analyzed the correlation between evidence of infection and neurologic outcome. We considered evidence of infection to be a positive result for a blood, sputum, or urine culture, and pneumonic infiltration on chest X-ray. Results: The average of the highest body temperature within 72 h after successful CPR was 38.4±0.9˚C for the unfavorable neurologic outcome group, which was significantly higherthan the value of 37.7±0.5˚C for the favorable neurologic outcome group (p=0.002). No significant correlation existed between neurologic outcome and age, place of cardiac arrest, duration of arrest, causes of cardiac arrest, and initial blood pressure after successful resuscitation. In hyperthermic group (n=l 8), eight patients showed the evidence of infection, but no significant correlation existed between the evidence of infection and neurologic outcome(p=0.850). Conclusion: Hyperthermia is a potential factor for an unfavorable neurologic recovery after successful CPR.