MWPC 위치검출기의 X-선 천체물리학에의 응용

남욱원,최철성,문신행,강희동 경북대학교 센서기술연구소 1990 센서技術學術大會論文集 Vol.1 No.1

1983 년경 국내에서도 과학탐사 로케트와 인공위성이 발사될 예정에 있으며 이에 따라 X-선 천체물리학을 위한 방사선 센서의 국내 개발이 시급히 요청되는 바이다. 따라서 현재 방사선계측에 많이 이용되고 있는 방사선 센서들 중 국내에서 개발되어온 MWPC위치검출기를 소개하고 인공위성 혹은 과학탐사로케트에 탑재되어 X-선 천체물리학연구에 이용될 경우 연구 개발되어 나가야 할 방향을 제시하고자 한다. Domestic sounding rocket and scientific satellite are scheduled to launch around 1993. The development of radiation sensor is required to observe X-rays coming from celestial bodies by the use of those space vehicleS. In this study we introduce the multi-wire position sensitive detector and the future works of onboard detector for X-ray astrophysics.

항갑상선제로 치료한 그레이브스병 환자의 관해예측인자

남일송,윤여일,김선규,김용현,이주영,목지오,윤석기,김철희,김영선,변동원,서교일,유명희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: Most cases of Graves' disease have been treated by antithyroid drugs in Korea. The major drawbacks of antithyroid drugs are the relative high rate of relapse and the inconvinience of long term therapy. Measurement of TBII and TRH stimulation test have been considered as the most reliable tests predicting relapse, but the predictive power is not high enough to use in clinical situation. This study was performed to find good prognostic indicators in Graves' disease patients after the discontinuation of antithyroid drug therapy. Subjects and methods : We restrospectively evaluated 96 patients with Graves' disease who showed normal TRH test at the end of antithyroid drug therapy and were followed for more than one year. Serum T3, T4, T3/T4 ratio, TBII, Anti-TPO Ab and TGAb levels were measured at the time of diagnosis and at the end of therapy. Two to three months after withdrawal of antithyroid medication, serum TSH and free T3 responses to TRH were examined. These parameters were compared between the relapse group and the remission group. Results : Among the 96 patients, 22 patients(22.9%) relapsed(Group Ⅱ) and 74 patients(77.1%) remained in remmision(Group Ⅰ). No significant difference was observed between the relapse and the remission group in clinical parameters, serum T3, T4, TSH, T3/T4 ratio, TBⅡ and Anti-TPO Ab determined before and after treatment. Serum TSH and free T3 levels measured after TRH stimulation were also similar in both groups. Serum TGAb levels determined at the end of treatment were significantly higher in the remission group(p<0.05). Relapse following the discontinuation of therapy occured within 24 months in 72.7% of the relapsed cases. After 24 months, relapse rate was reduced significantly. Conclusion : These results suggest that high serum TGAb levels could be a favorable prognostic indicator for the long term remission of Graves' disease treated with antithyroid drugs, and may suggest that Hashimoto's thyroiditis is combined with Graves' disease in those patients.

활성 알루미나의 제조방법에 관한 연구

남영우,김현철,황희연 崇實大學校 生産技術硏究所 1994 論文集 Vol.24 No.-

Aluminum hydroxide gels were formed from aluminum salts by precipitation method. These gels were aged and calcined to get γ- alumina. The effects of aging condition for aluminum hydroxide gels on the physical properties of γ- alumina were tested varying aging pH, time and temperature using aluminum sulfate as starting materials. The effect of starting materials were tested using aluminum sulfate, nitrate and chloride salts. Activated alumina prepared from Boehmite aged under the condition of pH 11 and 170℃ showed high surface area and large pore volume. Aging time above 1 day showed a little effect on the properties of activated alumina. Optimum aluminum salt concentration for high surface area and large pore volume was 4 wt%.

조기 발병한 정신증적 장애에서 자기공명영상을 이용한 측뇌실에 대한 구조적인 예비연구

이윤희,강민희,김철응,이정섭,배재남,홍강의 대한소아청소년정신의학회 2001 소아청소년정신의학 Vol.12 No.2

연구목적:측뇌실의 확장은 성인기의 정신분열병에서 잘 확립되는 소견이지만, 조기에 발병한 정신증적 장애에서는 아직 논란이 있다. 본 연구에서는 자기공명영상을 이용한 후향적인 방법을 통하여 지금까지 비교적 연구가 많이 시행되지 않았던 조기발병한 정신분열증·양극성 장애 환아들을 대상으로 측뇌실의 구조적인 이상을 연구하여, 이러한 뇌의 구조적 이상이 병의 초기부터 시작되어 정상과는 다른 경과로 진행되는 것인가를 알아보고자 하였다 방법:정신분열병과 양극성 장애의 DSM-Ⅲ-R 진단 기준에 부합하는 14명의 환아(평균 연령 14.0세,표준편차 2.1)와 26명의 두통 대조군에서 뇌자기공명 영상상을 후향적으로 모집하였다. 분석을 위하여 측뇌실이 가장 잘 보이는 축 영상(axial image)를 선택하였다. 뇌자기공명영상상은 평판형 스캐너로 읽어들여서 NIH IMAGE 프로그램을 통하여 분석하였다. 결과:환자군에서는 측뇌실 크기, 측뇌실확장지수가 연령의 증가에 따라 함께 증가하는 상관관계를 나타내었으나, 대조군에서는 연령과 측뇌실 크기, 측뇌실확장지수 등이 유의한 상관관계를 보이지 않았다. 환자군에서는 정상군에서 보이는 좌우 측뇌실 비대칭성이 소실된 결과를 보였다. 그리고 통계적으로 유의한 정도는 아니었으나 환자군이 대조군에 비해 측뇌실과 측뇌실확장지수가 큰 경향을 보였다. 결론:정신증적 환자에서의 뇌의 구조적 이상은 병의 비교적 초기 경과에서부터 시작되며, 정상과는 다소 다른 경과를 취하여 진행한다는 것을 시사하는 결과라 할 수 있다. Objective : The enlargement of the lateral ventricle is well established finding in adult-onset schizophrenia, but in the patients with early-onset psychotic disorder(EOPD) is still controversal. To identify structural abnormalities of the lateral ventricle in patients with EOPD and difference of the brain developmental course in EOPD group, planimetrical assessment of the lateral ventricle was conducted by means of retrospective quantitative neuroimaging. Methods : The brain MR images of 14 patients with EOPD(mean age 14.0±2.1 years) who met the DSM-Ⅲ-R diagnostic criteria for schizophrenia and bipolar disorder and 24 control subjects with simple headache(mean age 10.0±2.1 years) were collected. Single best view for the lateral ventricle, one axial slice was selected for analysis. MR images were redigitalized with flatbed scanner and data were analyzed with NIH IMAGE software. Results : In the patients with EOPD, there were significant correlations between aging and lateral ventricular sizes and between aging and ventricular brain ratio(VBR). The statistical significance of normal asymmetry of the lateral ventricle was not observer for the EOPD group. The EOPD group had larger lateral ventricular sizes and VBR than control group, but these results were not statistically significant. Conclusion : These findings suggest that the brain abnormalities in patients with EOPD progress from the earlier course of the disorders and the course of brain development in EOPD group is different from control group.

플라즈마를 이용한 유리섬유강화 복합절연재료의 표면처리에 관한 연구

이규철,남창우,김희대,황영한,김경석 울산대학교 1997 공학연구논문집 Vol.28 No.1

본 연구에서는 에폭시계 복합 절연재료 Glass-cloth/Epoxy 의 계면 접착특성을 향상시키기 위하여 표면처리 조건에 따라 각각 복합 절연재료를 제작하였고, 전기·기계적특성의 상관관계를 다음과 같은 실험을 행하여 비교하였다. Glass의 젖음의 정도를 평가하기 위하여 표면처리 조건에 따라 주위온도 80[℃]에서 접촉각을 측정하였고, 주위온도 및 인가전압을 변화시키면서 비유전율(εr), 유전정접(tanδ) 및 전기적 절연강도를 측정하였다. 기계적 특성을 측정한 후에 파단면의 형상을 SEM으로 분석, 검토하였다. 실험 결과, (1) 주위온도가 상승함에 따라 비유전율 및 유전정접은 증가하였고, 전기적 절연강도는 감소하였으며 플라즈마 처리함으로서 전기·기계적특성은 전반적으로 향상되었다. (2) 접촉각 측정 주위온도가 80[℃]일 때, 표면처리 조건에 따른 젖음성은 각각 다르게 나타났고 플라즈마 처리효과는 표면세정, 미세요철, 표면대전 및 젖음성의 감소와 같은 복합효과로 볼 수 있다. (4) 전기·기계적특성의 관점에서 복합 절연재료의 경화온도가 80[℃]일 때, Glass-cloth/Epoxy복합 절연재료의 최적처리시간은 3분 정도로 나타났다. The Glass-cloth/Epoxy composite insulating materials for this study have been prepared with several different surface treatmenttechniquen such as untreatment ultrasonic treatment and plasma treatment, and their electrical and mechanical characteristics have been compared each other. It has been found that plasma-treated glass has the smallest contact angle with a drop of epoxy. The plasma-treated composite materials have superior dielectric strength and mechanical tensile-strength compared to the materials subjected to other surface treatments. Also, the experiment showed that there exists an optimum plasma treatment duration for improving the interfacial characteristics of the composite insulating materials. The optimum plasma treatment durations are about 3 minutes for Glass-cloth/Epoxy at 80[℃]. Longer plasma treatment has been appeared to degrade the interfacial characteristics.

우묵사스레피(Eurya emarginata)의 플라보노이드 화합물의 분리 및 동정

양홍철,박수영,강희경,이남호 제주대학교 생명과학연구소 2001 제주생명과학연구 Vol.4 No.-

The extracts of Eurya emarginata showed inhibitory effect on the growth of HL-60 leukemia cells. So, 80% methanol(MeOH) extract of its leaves was partitioned to hexane, ethyl acetate, n-butanol and residual water fractions. The ethyl acetate fraction, which showed desirable activities, was further purified using SiO2 column chromatography(CC) followed by reverse phase silica gel CC, then another normal CC to give fraction 4-1-8 as a pure compound. The compound 4-1-8 was analyzed by NMR spectrometry using 1H, 13C, DEPT, HMQC and HMBC spectra, and finally proved to be well-known flavono glycoside, Quercitrin.

Carbamazepine에 의해 발생한 다형 홍반, 독성 간염, 백혈구 및 혈소판 감소증 1례

김희철,정성원,박영남,정철호,김정범 대한생물치료정신의학회 1999 생물치료정신의학 Vol.5 No.1

이종 접합부재의 계면균열에 대한 파괴인성의 평가방법

정남용,박철희 崇實大學校 生産技術硏究所 2002 論文集 Vol.32 No.-

The application of bonded dissimilar materials to such indurstries as automobiles, aircraft, rolling stock, electronic devices and engineering stuctures is increasing gradually because these materials, compared to the homogeneous materials, have many advantages for material properties. In spite of such wide applications of bonded dissimilar materials, the evaluation method of fracture toughness on interface crack in the bonded components has not been established clearly. In this paper, the stress intensity factors were analyzed by boundary element method(BEM) for the bonded scarf joints with a crack, respectively. From static fracture experiments of the bonded scarf joints, an evaluation of fracture toughness on interface crack in the bonded components was proposed and discussed.

PILOMATRICOMA 치험 1례

김은철,이창우,임창준,이동근,김수남,양희창 大韓顎顔面成形再建外科學會 1990 Maxillofacial Plastic Reconstructive Surgery Vol.12 No.3

The pilomatricoma (calcifying epithelioma of Malherbe) is rare benign hard, spherical and freely movable cutaneous tumor, which was differentiated from hair cells, particulary hair cortex cells. It is usually occured as a single, asymptomatic, 0.5 cm to 3.0 cm sized, deep seated, firm nodule, covered by normal or pink skin. It arises chiefly in young people, including children, and most often in the head, neck and upper extrimites. The authers experienced a case of pilomatricoma which occured in preauricular region. This case was summarized as follows. 1. 10 years old female has suffered from hard subepidermal mass on preauricular area and she visited our out patient clinic. So we performed surgical extirpation and the excised specimen was pathologically examined. 2. Grossly the tumor measures 2.0 cm in diameter and firm, bosselated, spherical shaped which covered by a thin layer of fibrous tissue. On cut section, it shows spicular gritty surfaces, well encapsulation, interwoven and keratotic lamellae. 3. Histopathologically, the epithelial masses of the tumor are composed of two type of cells, basophilic cells and shodow cells. The basophilic cells resemble hair matrix cells which posses round or elogated, deeply basophilic nuclei and scanty cytoplasm.The shadow cells show a central, unstained shadow at the site of the lost nucleus. Gradual development of basophilic cells into shadow cells can be observed. Foci of calcification are present within the lobule of shadow cells. The stroma of the tumor shows a considerable foreign body giant cell reaction adjacent to the shadow cells. 4. No recurrence was observed until post - operative 40 months.

여성의 피부관리실태와 관련요인

구재희,남철현,최연희,배향선,신옥순,양숙희,이명옥 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

This study was conducted to analyze aspects of women's skin care and related factors in order to contribute to community residents's right skin care. The subjects of this study was 800 women who were 15 to 65 years old. Data were collected in Daegu City and Kyungsan City from June 21, 2002 to August 18, 2002. The results of this study can be summarized as follows. 1. According to socio-demographic characteristics of the respondents, 26.8% of them were in twenties. 50.9% of them was students at colleges or graduated from collges. 38.3% was students and 37.5% was housewives. 55.5% belonged to the middle economic class. 2. 47.9% of the respondents replied that they were in good health. 57.2% of them had fair skin, while 25.1% had dark skin. According to health condition of face skin, 61.5% was in regular condition, while 26.0% was in bad condition. 29.9% had drying face skin and 21.3% had neutral or complex character of face skin. 3. Among the reasons they had trouble with face skin, the proportion of having the rough skin was highest (25.0%). 16.6% replied that they had trouble with a lot of wrinkles and 16.3% replied that they had trouble with dark face skin. 25.4% responded that their face skin was too tight. 13.3% replied that they had trouble with scars. 4. The factors significantly influencing the experience of skin care were age, education level, residence, experience of side effect of cosmetics, experience of skin diseases on face or body, experience of trouble after receiving skin care, and experience of trouble with acne. From above results, it can be concluded that selection of proper skin care rooms is important in receiving desirable skin care and preventing side effect related to skin care. The women also must be cautious in selecting and using cosmetics and massage pack. The government, related organizations, and skin and beauty specialists must make efforts to develop education programs for healthy skin care.