Differential Localization of ODAM in Periodontitis with Similar Clinical Severities

황금빛,박용현,서유미,배현숙,지숙,박주철 대한구강해부학회 2021 대한구강해부학회지 Vol.42 No.1

Odontogenic ameloblast-associated protein (ODAM) reportedly plays an important role in maintaining periodontal integrity. We aimed to investigate the cause of different ODAM values in the gingival crevicular fluid (GCF) and discrepancies between GCF ODAM values and histological ODAM distribution in periodontal disease. ODAM concentration in the GCF of nine adult patients with severe periodontitis and ODAM distribution in the gingival tissues of three adult patients were analyzed using enzyme-linked immunosorbent assay and immunohistochemistry (IHC), respectively. ODAM in the GCF was detected in six samples but not in the remaining three samples; no differences were observed in the clinical characteristics between the ODAM-positive and ODAM-negative groups. ODAM was observed in the junctional epithelium of healthy gingival tissue by IHC analyses. There were two different ODAM expression patterns in gingival tissues with periodontitis of similar clinical severities, no overall expression or localized overexpression in the connective tissue layer. ODAM in severe periodontitis was secreted into the GCF or otherwise released into the connective tissue. Although clinically diagnosed as the same degree of periodontitis, the expression pattern of ODAM may differ according to whether ODAM can function as a junctional protein.

자연관해를 보인 위에 국한된 랑게르한스 세포 조직구증 1예

황금빛,함준수,황수빈,정숙현,이준행 대한상부위장관ㆍ헬리코박터학회 2015 Korean Journal of Helicobacter Upper Gastrointesti Vol.15 No.4

A 44-year-old male was followed-up with esophagogastroduodenoscopy due to an esophageal submucosal tumor. On the lesser curvature of the gastric low body, a 0.5 cm sized round elevated lesion with hyperemia was noticed. Two pieces of biopsy were taken from this lesion for histopathologic examination. Histology showed Langerhans cell infiltration. Immunohistochemical staining was positive for CD1a antigen, which confirmed the diagnosis of Langerhans cell histiocytosis. There was no evidence of other organ involvement. The lesions spontaneously disappeared 4 months later without any treatment. We report a very rare case of gastric Langerhans cell histiocytosis. (Korean J Helicobacter Up Gastrointest Res 2015;15:-273)

A Case of Giant Hydronephrosis Hidden by Obesity in an 11-year-old Boy

황금빛,황인찬,추설호,김현기,배기수 대한소아신장학회 2017 Childhood kidney diseases Vol.21 No.2

Giant hydronephrosis (GH) is a rare urological entity and usually presents with more than a liter of fluid in the collecting system. It may mimic a progressive and benign abdominal cystic tumor. We report a case of GH in an 11-year-old obese boy who presented with abdominal distension and dyspnea on exercise. Hydronephrosis was caused by ureteropelvic junction obstruction, with 2,300 mL of fluid in the collecting system. Diagnostic and therapeutic features of this case are discussed, with reference to current literature.

치과 임상기관별 치과 진료용 의자의 세균 수 비교

황금빛,성유경,유아련,이은영,정지영,현수정,서미화,김지연,전현선 한국치위생감염관리학회 2015 한국임상치위생학회지 Vol.3 No.2

The aim of the study was to compare of bacterial counts on dental unit chairs among various dental clinical institutions. A total of 9 frequently used unit chairs from W University Hospital, Y University dental hygiene laboratory, local clinic A, B were chosen. Bacterial samples were collected from three parts (spittoon, 3-way syringe handle, bracket table) of each unit chair and then incubated for 48 hours at 37℃ after spreading on BHI agar. We measured the bacterial counts using CFU unit. Kruskal-Wallis and Man Whitney tests were utilized to compare the difference among multiple groups and two groups, respectively using SPSS Statistics Program version 21.0 (p<0.05). The median of bacterial counts in spittoon from local clinics was 7535.00CFU/㎖ which was the highest among all groups. The median score of the W University hospital, The Y University dental hygiene laboratory, and local clinics were 496.17 CFU/㎖, 53.08 CFU/㎖, and 3261.42 CFU/㎖, respectively. According to the result, p-value among groups was 0.034 and it showed statistically significant (P<0.05). Proper surface disinfection is necessary to all institutions. Health care providers should be aware of the importance of systematic surface disinfection in dental environment. Guideline should be established as soon as possible to ensure efficient and practical surface disinfection.

Prevalence of autoimmune thyroiditis in patients with type 1 diabetes: a long-term follow-up study

황금빛,윤종서,박규정,이해상,황진순 대한소아내분비학회 2018 Annals of Pediatirc Endocrinology & Metabolism Vol.23 No.1

Purpose: Type 1 diabetes mellitus (DM) is associated with autoimmune diseases such as thyroiditis. Therefore, we aimed to investigate the prevalence of autoimmune thyroiditis in patients with type 1 DM. Methods: A total of 102 patients who were diagnosed and followed up (mean age, 8.1±4.0 years) in Ajou University Hospital were enrolled in this study. All the patients were evaluated for beta cell autoimmunity, including insulin autoantibody, glutamic acid decarboxylase antibodies (GADA), and islet cell antibody. Moreover, autoantibodies to thyroid peroxidase and thyroglobulin were assessed at initial diagnosis and annually thereafter. Results: The mean patient age (49 men and 53 women) was 19.2±4.8 years. The prevalence of at least one thyroid antibody was 30.4%. Patients with thyroid antibodies had a significantly higher frequency of GADA at the time of the diagnosis. Autoimmune thyroiditis was more prevalent in the older age group. GADA was a significant risk factor for development of thyroid autoantibodies after diagnosis of type 1 DM (odds ratio, 4.45; 95% confidence interval, 1.399–14.153). Conclusion: In patients with type 1 DM, the prevalence of autoimmune thyroiditis was higher than in the general population. Moreover, GADA positivity at diagnosis was associated with thyroid autoimmunity.

잡지 보그 표지 이미지의 립스틱 색상 트렌드 연구 - 1940년도 ~ 2010년을 중심으로 -

황금빛누리 ( Geum-vit-nu-ri Hwang ),이보람 ( Bo-ram Lee ),임희경 ( Hee-kyung Lim ) 한국미용예술경영학회 2013 미용예술경영연구 Vol.7 No.3

The purpose of this study is to investigate and analyse the use of the colors of the lipsticks used to adorn the Vogue magazine cover page models and figure out the trend of the lipstick color on the basis of the current study. For this study, the cover page of the Vogue published between 1940 to 2010 were collected and the RGB value of the lipstick color that the model was wearing was analysed and the H/VC value was extracted. Tone was carefully added to help the analysing process. The result of this study is as follows. In the first, R color set the trend in lipstick color, even if Time period is changed. but, lipstick tone depends on Time period. Second, In spite of changed Time and Season, R color possessing S tone will set the trend now and for ever. On the basis of analysis result, This thesis is to suggest basic information in order to understanding lipstick trend. And, this thesis tends to a better grasping flow of lipstick market in the future in that it is study how its trend is changing with times.

성인 여성의 화장품 유통채널별 인식도와 구매의도에 관한 연구

황금빛누리 ( Geumvitnuri Hwang ),신세영 ( Sae Young Shin ) 한국패션비즈니스학회 2016 패션 비즈니스 Vol.20 No.1

Korean cosmetic distribution channels were formerly divided into sales visits and specialty shops, which made up the entire cosmetics market. However, recently the market and cosmetic distribution channels have become much more diversified. Thus, research for this study focused on the usage and purchase situations of cosmetic distribution channels depending on cosmetic type perception. This study also focused on the intent to purchase cosmetics by a cosmetic distribution channel in order to provide a precise cognitive background of consumers regarding cosmetic distribution channels. In doing so, the competitiveness of those channels could be procured and the causal relationships between these variables can be investigated. To achieve these purposes, the research model and hypotheses were derived through literature research on the cosmetics industry, cosmetic distribution channels, and consumers’ intent to purchase. A survey was implemented from September 1st to 14th, 2014 for empirical testing. and was given to female consumers in their 20s. 468 out of 500 surveys were collected; a total of 415 were used for analysis while the others were excluded due to with unreliable responses. The SPSS 21.0 program was used for analysis of materials. The overall conclusion of this study is that there is a relationship between perception of cosmetic distribution channels and intent to purchase. The above research results may stimulate establishment of marketing implications and research material when establishing marketing strategies to promote cosmetic distribution and consumption.

Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium simiae : The First Reported Case in South Korea Suk

정석현,김수영,이현,함준수,황금빛,신선혜,정명진,이승헌,신성재,고원중 대한결핵및호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4

This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae . The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65 , rpoB , 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.

혈액종양 : 다발성 전이를 동반한 설암 환자의 골격근전이와 β-HCG 상승 1예

함준수 ( Jun Soo Ham ),황금빛 ( Keum Bit Hwang ),황수빈 ( Subin Hwang ),정숙현 ( Suk Hyeon Jeong ),이지윤 ( Ji Yun Lee ),이세훈 ( Se Hoon Lee ),박근칠 ( Keunchil Park ) 대한내과학회 2015 대한내과학회지 Vol.89 No.6

Metastases to skeletal muscle and paraneoplastic syndromes involving β-human chorionic gonadotropin (HCG) production are an extremely rare manifestation of head and neck squamous cell carcinoma. We report a patient with a β-HCG-secreting squamous cell carcinoma of the tongue with diffuse metastases involving skeletal muscle. A 47 year old female, who was being treated heavily with palliative chemotherapy for metastatic tongue cancer, was admitted with a palpable thigh mass and pain. A magnetic resonance image showed an intramuscular metastasis in the thigh. Ultrasound-guided biopsy of the thigh mass confirmed metastatic squamous cell carcinoma. She was scheduled for enrollment into a clinical trial; however, a positive serum β-HCG test was noticed. There was no evidence of pregnancy or a trophoblastic or non-trophoblastic tumor secreting β-HCG. Finally, she was revealed to have a paraneoplastic syndrome with diffuse metastases and was ultimately referred for palliative care. We review the literature of previously reported cases of an increase of β-HCG in patients with head and neck cancer. (Korean J Med 2015;89:719-722)

헤어살롱의 촉진서비스품질과 지각된 가치가 재구매의도에 미치는 영향

이보람 ( Bo-ram Lee ),황금빛누리 ( Geum-vit-nu-ri Hwang ) 한국미용예술경영학회 2014 미용예술경영연구 Vol.8 No.2

The purpose of this study is to increase the service quality of promotion in the hair salon. It will help to provide the service of promoting a better quality of the beauty industry in the future. This study provided the theoretical basis, and based on the study of literature in order to analyze the impact on repurchase intention of promoting hair salon service quality and perceived value for the empirical investigation without limits from 20 50 each age group was up by more than a hair salon that uses the survey. Survey were analyzed using SPSS 16.0 program employs 199 part 1, except insincere or incomplete parts of a total of 200 questionnaires distributed wealth from 1 March 2014 to 30 June 2014. As a result, The monetary value that is perceived by the others and experience the discounts and the discounts never experienced a hair salon, most people, most were using a relatively simple program, such as the promotion of the points earned or Morning Minute. Marketing research will also need to take advantage of a discount coupon and discount affiliate, earn points program of promoting preference for hair salon services and partnership discount coupons, earn points higher had know that an increase of the repurchase.