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구강해부학에 관한 Bartolomeo Eustachio의 업적: “Libellus de Dentibus”의 주요 내용
이영훈,박병건 대한구강해부학회 2018 대한구강해부학회지 Vol.39 No.1
When it became widely known recently that Bartolomeo Eustachio, a well-known anatomist who named the Eustachian tube (pharyngotympanic tube), made very great contributions towards the anatomy and physiology of the dentition, including the first descriptions of the structure of the dental pulp and the periodontal membrane, he began to be called ‘the Father of Dental Anatomy’. He published the first book devoted to the structure and function of the teeth, “Libellus de Dentibus”, in 1563. It has been translated into several languages. Here we introduce the main contents of the booklet translated into English as “A Little Treaties On The Teeth” by Chernin and Shaklar in 1999, and once again honor Bartolomeo Eustachio's great work in dental anatomy. 우리에게는 귀인두관(Eustachian tube)을 명명한 해부학자로 잘 알려진 Bartolomeo Eustachio가 치아의 치수와 치주인대에 대해서 처음 언급한 것을 포함해서 구강해부학에 관해 매우 중요한 기여를 하였다는사실이 최근에 널리 알려짐에 따라, 그를 ‘구강해부학의 아버지(Father of Dental Anatomy)’라고 부르자는주장이 제기되었다. Eustachio는 치아에 관한 최초의 단행본 책자인 “Libellus de Dentibus”를 1563년에 발간하였다. 그 동안 이 책은 여러 언어로 소개되기 시작했는데, 본 논문에서는 Chernin과 Shaklar가 1999년에 발간한 라틴어·영문 대조판 책(A Little Treatise On The Teeth)과 2000년에 이것에 대해 요약 발표한 논문을 주로 활용하여 “Libellus de Dentibus”의 주요 내용을 소개함으로써, 구강해부학에 관한 Bartolomeo Eustachio의 위대한 업적을 다시 한번 기리고자 한다.
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Cytosine Arabinoside와 Polyribonucleotides가 흰쥐 切齒齒髓組織에 미치는 影向에 關한 硏究
金成龍 대한구강해부학회 1977 대한구강해부학회지 Vol.1 No.1
Male rats, weighing about 100gm were used throughout all experiments. TheY were divided to cytosine arabinoside group, cytosine arabinoside group receiving polyribonucleotides and control group. Experimental animals were given an intramuscular injection of cytosine, arabinoside 50mg per kg of body weight. Polyadenylic acid (poly A) and polyuridylic acid (poly U), were used in this investigation. Experimental rats, were given an intraperitoneal injection of poly A:U(lmg/kg) , 24 hours prior to sacrifice. The animals were sacrificed 1, 3, 5, 7, 10 and 14 days after injection of these drugs. For determination of DNA content, the diplienylamine, reaction of Burton was used. Total protein of the pulp tissues were measured by the Folin phenol reagent. The intensity of the subsequent color reaction was determined by absorbance at 600mμ for DNA and 750mμ for protein in the spectronic 20 spectrometer. The results were compared with data derived from calf thymus DNA and bovine serum albumin as standard and expressed as μg of DNA and protein. To establish the relative cellularity of the pulp tissues from different groups, D A and protein content per mg of tissue were assessed. The objectives of this study were to evaluate the effects of cytosine arabinoside group and cytosine arabinoside group receiving poly A: U on the biochemical functioning of pulp tissues in rat incisors. The results were as follows; 1. The effects of cytosine arabinoside group and cytosine arabinoside group receiving polyribonucleotides on the body weight and weight of pulp tissues were produced significant decrease during the first 5th days followed by a gradual recovery thereafter. The body weight and pulp tissue weight of the cytosine arabinoside group receiving polyribonucleotides were higher than that not receiving polyribonucleotides. 2. The DNA and protein content in the groups receiving polyribonucleotides were higher than those not injected with nucleotide mixture. 3. The effects of cytosine arabinoside group without and with poly A:U on t he DNA and protein content of the pulp tissues were produced a considerable decrease during the first 5th days followed by gradual recovery thereafter. 4. Therefore, the results suggest that poly A:U might have a limited stimulatory effect on the DNA and protein synthesis of the pulp tissues in rat incisors. It has been shown that synthetic, polyribonucleotides, when used in an appropriate quantity were able to enhance DNA and protein synthesis in the pulp tissues of the rat incisors.
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