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2000년도 부산지역에서 분리된 살모넬라속균의 혈청학적 분포 및 항균제 감수성
차인호,민상기,박은희,김미희,진성현,박지현,이영숙,이상훈 한국생명과학회 2001 생명과학회지 Vol.11 No.3
A total of 79 Salmonella spp. were isolated from Pusan area in 2000. The serotypes of 79 Salmonella isolates were classified as 42 strains of S. typhi(53.1%), 24 strains of S. enteritidis(30.4%), 9 strains of S. montevideo(11.4%), 2 strains of S. typhimurium(2.5%), 1 strain of S. infantis(1.3%) and 1 strain of S. indiana(1.3%) strains(16.5%) of Salmonella sp. were isolated at May July, respectively. The isolates of S. typhi were sensitive to most sntibiotics except streptomycin. All isolates of S. typhi were especially sensitive to tobramycin, gentamicin, colistin, kanamycin, samikacin, sulfamethozazole/ trimethoprim, cefriaxone, ceftazdime, cifrofloxacin, cefoxitin and cefotaxime. Isolates of S. enteritidis wer presented higher resistance than isolates of S. typhi. Twenty-four strains of S. enteritidis were sensitive to kanamycin, amikacin cifrofloxacin, cefoxitin and cefotaxime, however 13 strains(54.2%) of S. enteritidis were resistant to carbenicillin, ampicillin and ticarcillin. Nine strains of S. montevideo were sensitive to most antibiotics except carbenicillin and streptomycin. Each 1 stain of S. indiana and S. infantis was sensitive to most antibiotics used in this study except streptomycin. Three kinds of resistant pattern (CB, SM, TE, AM, TC). In the case of S. enteritidis isolates, 9 kinds resistant pattern were detected. Most frequent resistant pattern of S. enteritidis isolates was CB, AM, TC type(16.7%)
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차인호,송인호 사단법인 한국브랜드디자인학회 2016 브랜드디자인학연구 Vol.14 No.2
In this study, light and dark in our visual environment - color - in the form of a message horn elements are directing mixed in multiple simultaneous, or to highlight the elements that designers seem important in space, and selecting a priority, there is a basic theoretical meaning of the methodology for adjusting the visual production. Through theoretical considerations, it is in the hierarchy of each perception of the message currently organize related documents of messages each study concerning contrast and color, and conducted an experiment to prove the hypothesis of this study that the contrast is priority to color, to analyze the experimental results. Each cognitive element message via results and analysis of experiments proved hypothesis that form the rank contrast, color, in this order form. Hierarchy of the portion where the contrast is not clearly formed in the order of the colors of RGB, which was investigated to be applied to the case of the color mixture. After the brightness contrast step in one stage in each cognitive hierarchy of messages, is rank the interaction between the color in two stages, how much conditions of luminosity contrast ratio between the dark bright at the stage of moving in two stages from the first stage when formed, or it can act in two stages, and specifically presents a quantitative indication, in the cognitive hierarchy of messages between colors, by performing an additional experiment various samples, throughout the study it is necessary to verify the apparent since contents. 이 연구는 우리의 시각적 환경에서 명암-색상-형태의 시지각적 요소가 동시다발적으로 혼재하며 연출되는 가운데 디자이너가 공간에서 중요하게 생각되는 요소를 부각시키거나 우선순위를 선정하여 시각적 연출을 조정하기 위한 방법론의 기초이론으로 의미가 있다. 이론적 고찰을 통하여 현재 명암과 색채에 관한 시지각 연구의 관련자료를 정리하고 시지각 인지의 위계에 있어 명암이 색상에 우선한다는 이 연구의 가설을 증명하기 위한 실험을 진행하고 실험결과를 분석한다. 실험의 결과와 분석을 통해 시지각 인지요소는 명암, 색상, 형태의 순으로 위계를 형성한다는 가설을 증명하였다. 명암대비가 확실하지 않은 부분에 대한 위계는 색상의 RGB순으로 형성되며, 이는 혼색의 경우에도 적용된다는 사실을 규명하였다. 시지각 인지위계에서 1단계로 명도대비 단계 이후에 2단계로 색채 간의 위계가 작용되는데 1단계에서 2단계로 넘어가는 단계에서 밝고 어둡기 간의 명도대비 비율조건이 어느 정도로 형성될 때, 2단계로 작용할 수 있는지 정량적 지표를 구체적으로 제시하고, 색채 간의 시지각 인지위계에서도 다양한 시료로 추가실험을 진행하여 이 연구를 통해 밝혀진 내용들을 검증할 필요가 있다.
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Polymorphisms of CYP1A1 and GSTM1 Genes and Susceptibility to Oral Cancer
차인호,박종윤,정원윤,최민아,김형준,박광균 연세대학교의과대학 2007 Yonsei medical journal Vol.48 No.2
Purpose: Oral cancer is the fifth most common form of cancer in the world and comprises 6.5% of all cancer deaths. Since one of the major risk factors for oral cancer is tobacco use, we hypothesized that polymorphic genes coding for tobacco carcinogen-metabolizing enzymes may play a role in oral cancer susceptibility. Materials and Methods: To investigate the association between polymorphisms of the CYP1A1 and GSTM1 genes and risks for oral squamous cell carcinoma (OSCC) in the Korean population, the prevalence of the CYP1A1 Mspl and GSTM1 null polymorphisms were examined in 72 patients with histologically confirmed primary OSCC, as well as in 221 healthy control subjects. Results: A significant risk increase for oral cancer was observed among subjects with the homozygous CYP1A1 (m2/m2) genotype (OR=3.8, 95% CI=1.9-7.7), but not the GSTM1 null genotype (OR=0.7, 95% CI=0.4-1.3). Risk for oral cancer was significantly increased in subjects with the homozygous CYP1A1 (m2/m2) genotype, regardless of smoking history (smokers; OR=4.4; 95% CI=1.2-16.3; non- smokers OR=4.9; 95% CI=1.9-12.5). Using the potentially most protective genotype GSTM1 (+)/CYP1A1 [(m1/m1)+ (m1/m2)] as the reference group, an increased risk for oral cancer was observed among subjects with the GSTM1 (+)/ CYP1A1 (m2/m2) (OR= 2.0, 95% CI=0.8-5.2), and GSTM1 (-)/ CYP1A1 (m2/m2) (OR=4.9, 95% CI=1.5-15.5) genotypes (p<0.009, (χ2 trend test). Conclusion: Our results suggest that individuals with a genotype of CYP1A1 (m2/m2) and GSTM1 (-) are highly susceptible for OSCC and that the CYP1A1 (m2/m2) genotype is closely associated with increased risk of OSCC in Koreans.
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구강악안면외과 영역에서의 MIDFACIAL DEGLOVING APPROACH의 유용성
차인호,윤현중,이의웅,Cha, In-Ho,Yoon, Hyun-Joong,Lee, Eui-Wung 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.3
In the treatment of maxillary lesion including a maxillary sinuses, most of oral and maxillofacial surgeons have used the vestibular incision or the Weber-Fergusson incision. However, the vestibular incision has disadvantage which it provides a rather limited exposure and the Weber-Fergusson incision leaves visible scar in the midface. Furthermore, because the scar is confined on unilateral side only, the technique is hesitated to apply especially in children, younger patients and women. Since Casson first introduced midfacial degloving technique, this approach has been used frequently to treat the lesion on nasal cavity, nasopharynx, skull base and paranasal sinuses by ENT surgeons. But, we think this technique can be used usefully in oral and maxillofacial regions. So, we experienced favorable results which it provided a proper exposure, no visible facial scar and it could be used on bilateral midfacial lesions.
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