포스타 전시 발표 : 순환기,호흡기 ; 재발성 기흉과 흉막 삼출로 발현된 특발성 과호산구증후군 1예

문정근,심재민,안철민,황상연,문진욱,강신명,박무석,김세규,장준,김성규,김영삼 대한내과학회 2004 대한내과학회 추계학술대회 Vol.2004 No.1

Newly Developed Aortic Dissection After Aorta Cannulation During Mitral Valve Surgery in a Patient With Marfan Syndrome

문정근,신미승,Hun Jin Lee,정욱진,박철현,박국양 대한심장학회 2012 Korean Circulation Journal Vol.42 No.6

We report a case of newly developed aortic dissection after aorta cannulation during mitral valve surgery in a patient with Marfan syn-drome. An unexpected fatal complication of cardiac surgery detected on postoperative imaging survey in Marfan syndrome patient and its surgical finding are described.

Clinical and Echocardiographic Findings of Newly Diagnosed Acute Decompensated Heart Failure in Elderly Patients

문정근,강석민,조인정,오재원,심재민,이상학,장양수,정남식 연세대학교의과대학 2011 Yonsei medical journal Vol.52 No.1

Purpose: Elderly patients (pts) (EPs; ≥ 65 years old) with newly diagnosed-acute decompensated heart failure (ND-ADHF) have not yet been studied. The aim of the present study was to investigate clinical characteristics, including echocardiographic findings and prognosis, for EPs with ND-ADHF and to compare those with non-elderly pts (NEPs). Materials and Methods: We retrospectively investigated 256 pts (144 males, 63.0 ± 14.8 years old) who were admitted to our hospital between January 2005 and March 2009 with ND-ADHF. Clinical characteristics and echocardiographic parameters were analyzed in EPs (n = 135, 58 males) and NEPs (n = 121, 86 males). Results: In intergroup comparison, female gender, diabetes mellitus,previous stroke and hypertension were more common in EPs. Body mass index (22.3 ± 4.5 vs. 24.0 ± 4.4 kg/m2), estimated glomerular filtration rate (54.8 ± 24.3 vs. 69.2 ± 30.7 mL/min/m2), C-reactive protein (28.5 ± 46.9 vs. 7.6 ± 11.6 mg/dL), hemoglobin (12.3 ± 2.1 vs. 13.6 ± 2.3 g/dL) and N-terminal pro-brain natriuretic peptide level (10,538.2 ± 10,942.3 vs. 6,771.0 ± 8,964.7 pg/mL) were significantly different (p < 0.05 for all). Early mitral inflow velocity to early diastolic mitral annular velocity (E/E’) was significantly higher in EPs than in NEPs (21.2 ± 9.4 vs. 18.0 ± 8.9, p < 0.05). During follow-up (44.7 ± 14.5 months), there were no significant differences in in-hospital mortality, re-hospitalization and cardiovascular mortality between EPs and NEPs (p = NS for all). Conclusion: EPs with ND-ADHF have different clinical characteristics and higher LV filling pressure when compared with NEPs. However, the clinical outcomes for NEPs with ND-ADHF are not necessarily more favorable than those for EPs.

Exploring Factors of Consumer’s Impulsive Buying Behavior in Mobile Social Commerce

문정근,곽나연,이중정 한국디지털정책학회 2019 디지털융복합연구 Vol.17 No.2

Mobile social commerce is one of the fastest growing distribution channels in recent years. Therefore, it is important to understand customer's buying behavior in mobile social commerce in order to continuously grow in the competitive mobile social commerce market. To achieve the purpose of this study is to investigate how impulsive buying behaviors are applied in mobile shopping and how factors affect impulse purchasing in online shopping. In order to verify the hypothesis, we surveyed the customers who have experiences of using mobile social commerce and analyzed 280 valid data by Smart PLS 3.0. As a result, it was confirmed that consumers' innovation and purchasing experience influenced impulse purchase in mobile social commerce, and scarcity messages among information attributes affect impulse buying. Through this study, impulsive buying behavior which is a frequently analyzed variable in an online shopping context will be extended to the mobile shopping context. and it will provide practical implications for customer strategy establishment in mobile social commerce market.

Prognostic Implication of Strain Analysis in Patients with ST-Segment Elevation Myocardial Infarction: One More Evidence for Ever-Debatable Topic

문정근 한국심초음파학회 2016 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.24 No.2

부신피질자극호르몬(ACTH)의 증가가 동반된 무증상 부신피질자극호르몬 분비세포 선종(Silent Corticotroph-cell Adenoma) 1예

문정근,박소영,조병철,이중민,이시훈,김유미,이유미,차봉수,이현철,임승길 대한내분비학회 2004 Endocrinology and metabolism Vol.19 No.5

A 48 year-old man was referred to our Department with a headache, and also presented with an elevated serum ACTH level, but without an elevated serum cortisol. Although there was no clinical evidence of Cushing's syndrome, a brain CT and MRI showed a 4×4.5cm² sized pituitary mass, which was successfully removed by a transsphenoidal approach(TSA). A histopathological examination revealed the mass to have an ACTH positive reaction. Therefore, through hormonal and pathological evaluation, a silent corticotroph-cell adenoma(SCCA), with an elevated serum ACTH level, was diagnosed.Although reports on SCCA have been recently increased, this case is reported because these kinds of tumor are still rare, and those SCCA with an elevated serum ACTH even more so 뇌하수체 선종 중에서 임상적으로 비 기능성의 특징 때문에 주로 거대선종의 형태로 발견되는 무증상 부신피질자극호르몬분비세포 선종(silent corticotrophcell adenoma; SCCA)은, 전체 뇌하수체 선종의 3.5% 정도를 차지하며, 전체 비 기능성 뇌하수체 선종의 6.0~8.1% 정도로 보고된 바 있다. SCCA는 코르티솔 등의 호르몬을 통한 임상 증상이 나타나지 않으나, 부신피질자극호르몬 분비 종양과 비슷한 정도의 임상적 악성도를 가지고 있으므로, 설사 쿠싱증후군이 나타나지 않더라도, 시야 장애, 두통 등을 비롯한 종괴 효과에 의한 증상이 있는 환자의 경우 의심해 볼 수 있는 질환이다. 저자들은 두통을 주소로 내원하였으나 쿠싱증후군의 증상을 찾아 볼 수 없던 환자에서, 혈청 부신피질자극호르몬 수치가 상승된 드문 형태의 SCCA를 진단하였고, 수술적 종괴 제거를 통해 치료한 1예를 경험하였기에 보고하는 바이다.

Fatal Renal Bleeding in a Patient Treated With Aggressive Antithrombotic Therapy After Recurrent Coronary Stent Thrombosis

문정근,이상학,양우인,고영국,한웅규,장양수 대한심장학회 2010 Korean Circulation Journal Vol.40 No.7

Triple antiplatelet therapy has been known to be superior to the conventional dual regimen for preventing stent thrombosis after coronary stenting, and the addition of oral anticoagulation to antiplatelet therapy is also considered an option. However,the risks and benefits of a triple antiplatelet regimen plus additional oral anticoagulation must be taken into account. Here,we report a case of fatal renal bleeding in a patient treated with triple antiplatelet plus oral anticoagulant therapy for the prevention of recurrent stent thrombosis.

비 허혈성 가역성 좌심부전 환자의 임상적 경과 및 영향 요인

문정근,임세중,심재민,안철민,강신애,박성하,최의영,고영국,강석민,하종원 대한심장학회 2006 Korean Circulation Journal Vol.36 No.1

Background and Objectives:About 25% of the patients with non-ischemic left ventricular (LV) systolic dysfunctionwill improve spontaneously. However, little has been known about the fate of the patients stricken withheart failure after recovery from LV dysfunction. We hypothesized that the patients who recovered from nonischemicLV dysfunction have a substantial risk for recurrent heart failure. Subjects and Methods:Fifty patients(32 males, mean age: 54.9±12.4 years) who recovered from systolic heart failure (LV ejection fraction; an EF of28.8±7.2% at the initial presentation) to near-normal (LVEF >40% and a 10% or more increase in the absolutevalue) were monitored for the recurrence of heart failure. Patients with significant coronary artery disease wereexcluded. The etiologies of heart failure were idiopathic dilated cardiomyopathy (n=39), alcoholic cardiomyopathy(n=7), adriamycin-induced cardiomyopathy (n=2), and tachycardia-induced cardiomyopathy (n=2). Afterrecovery of LV dysfunction, the patients were followed up for a mean of 41.0±26.3 months. Results:In 9patients (18%), the LV systolic dysfunction recurred during follow-up (LVEF 32.6±7.3%). There was no significantdifference in the baseline clinical and echocardiographic variables between the patients with and without recurrentheart failure. However, cessation of anti-heart failure medication was more frequently observed in thepatients with recurrent LV systolic dysfunction (55.6% vs 4.9%, respectively, p<0.05). Conclusion:Recurrentheart failure may ensue in the patients with reversible non-ischemic LV systolic dysfunction. The maintenance ofanti-heart failure medication in these patients may be a significant influencing factor for their clinical prognosis.(Korean Circulation J 2006;36:53-59) 배경 및 목적: 임상적으로 비 허혈성 좌심부전이 가역적으로 회복되는 경우 를 간혹 관찰할 수 있다. 하지만 이렇게 회복된 상태의 울혈성 심부전의 임상적 경과에 대한 연구는 미흡한 실정이다. 본 연구에서는 심부전에 대한 적절한 치료 후 가역적으로 회복된 비 허혈성 좌심부전 환자들을 대상으로, 울혈성 심부전이 임상적으로 회복되고 좌심실 구혈률이 정상화 되더라도, 재발 성 좌심부전이 발생할 가능성이 있다는 가정 하에 이들의 임상 적 경과와 이에 영향을 미치는 요인들을 조사하였다. 방 법: 임상적 평가와 심 초음파 소견 상 가역적 회복을 보인 비 허 혈성 좌심부전 환자 50명을 대상으로 하였다. 이들은 심부전의 최초 진단 시 NYHA(New York Heart Association) class가 III 혹은 IV였으며, 심 초음파상 좌심실 구혈률은 40% 미만이 었고, 전체 추적 관찰 기간은 48.4±15.3개월이었다. 이들 중 남자는 32명, 여자는 18명이었고 나이는 54.9±12.4세였으며, 최초 진단 시 좌심실 구혈률을 28.8±7.2%였다. 결 과: 울혈성 심부전의 원인 질환으로는 특발성 확장성 심근증 이 39명으로 가장 많았고, 이외에 알콜에 의한 확장성 심근증 7명, 아드리아마이신에 의한 확장성 심근증이 2명, 빈맥에 의한 심근증이 2명이었다. 이들은 심부전에 대한 적절한 치료 를 시작하고 나서 16.9±13.9개월 만에 좌심실 구혈률이 개 선되었으며(좌심실 구혈률>40% 및 절대적으로 10% 이상의 개선) 심부전의 증상은 모두 호전되었고, 이후 27.1±2.9개월 간 추적 관찰하였다. 하지만 모두 9명의 환자에게서 46.6± 31.7개월 만에 좌심 기능의 재 악화가 발생하였는데, 이들에게 는 감염, 알콜 남용 등의 심부전을 일시적으로 악화시킬 수 있는 특기할 만한 임상적 이유는 발견할 수 없었으며, 이들 중 5명은 심부전의 회복 후 항 심부전 약물을 중단한 환자들이었 다. 좌심 기능의 재 악화에는 항 심부전 약물의 중단 여부가 통 계적으로 유의한 요인으로 작용하였다. 결 론: 가역적으로 회복된 비 허혈성 좌심부전 환자들은, 좌심 기능 의 재 악화에 따른 재발성 심부전이 발생할 가능성이 있으므로, 추적 관찰이 필요하며, 또한 좌심 기능의 회복 후에도 항 심부 전 약물의 지속적 투여가 필요할 것으로 생각된다.

The Impact of Diabetes Mellitus on Vascular Biomarkers in Patients with End-Stage Renal Disease

문정근,박성하,이찬주,이상학,강석민,최동훈,유태현 연세대학교의과대학 2017 Yonsei medical journal Vol.58 No.1

Purpose: Diabetes mellitus (DM) is the most common cause of end-stage renal disease (ESRD) and an important risk factor forcardiovascular (CV) disease. We investigated the impact of DM on subclinical CV damage by comprehensive screening protocolin ESRD patients. Materials and Methods: Echocardiography, coronary computed tomography angiogram, 24-h ambulatory blood pressure monitoring,and central blood pressure with pulse wave velocity (PWV) were performed in 91 ESRD patients from the Cardiovascularand Metabolic disease Etiology Research Center-HIgh risk cohort. Results: The DM group (n=38) had higher systolic blood pressure than the non-DM group (n=53), however, other clinical CV riskfactors were not different between two groups. Central aortic systolic pressure (148.7±29.8 mm Hg vs. 133.7±27.0 mm Hg, p= 0.014),PWV (12.1±2.7 m/s vs. 9.4±2.1 m/s, p<0.001), and early mitral inflow to early mitral annulus velocity (16.7±6.4 vs. 13.7±5.9, p=0.026) were higher in the DM group. Although the prevalence of coronary artery disease (CAD) was not different between the DMand the non-DM group (95% vs. 84.4%, p=0.471), the severity of CAD was higher in the DM group (p=0.01). In multivariate regressionanalysis, DM was an independent determinant for central systolic pressure (p=0.011), PWV (p<0.001) and the prevalence ofCAD (p=0.046). Conclusion: Diabetic ESRD patients have higher central systolic pressure and more advanced arteriosclerosis than the non-DMcontrol group. These findings suggest that screening for subclinical CV damage may be helpful for diabetic ESRD patients.

전라삼현승무 복원에 관한 연구

문정근(Jung Kun Mun),김주화(Joo Hwa Kim) 한국사회체육학회 2010 한국사회체육학회지 Vol.0 No.40

Jeollasamhyeon SeungMoo(Buddhist dance) is a traditional dance. According to samhyeonyukgak handed down in Jeonju district. Generally it is composed 5 courses with yeombul, half-yeombul, guggeori, buknoreum, and taryeong. Considering movements, Jeollasamhyeon Buddhist dance, are mainly composed of powerful movements rather than refined styles whose origin is Jeong Jaseon(real name is Jeong Gap seon). Dance Team of the Jeollabuk-do Provincial Center for Korean Traditional Performing Arts reproduced Jeollasamhyeon SeungMoo through Jeon Gwangok, Jeong Hyeongin`s discipline, one of tchumsawi appearing through teaching-learning history from Jeong Jaseon to Park Geumseul. Jolla Sam Hyun SeungMoo is recognized as important national artistic assets which describes the dilemma of religious man versus his desire for worldly temptations. This dance is considered independent (which was not diluted by other regional influence), and considered important Korean artistic asset which can showcase Korean heritage for the world.