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우선희,이운정,박규남,최세민,최승필 대한중환자의학회 2009 Acute and Critical Care Vol.24 No.1
Background: Infectious complications commonly occur in the survivors of out-of-hospital cardiac arrest. The aim of our study was to describe the incidence, associated factors and outcome of infectious complications of the survivors of out-of-hospital cardiac arrest. Methods: We conducted a retrospective analysis of 75 patients who survived out-of-hospital cardiac arrest. We collected the data on the demographics, the modes of cardiac arrest, the duration of CPR, the dose of epinephrine, the use of hypothermia, new infections, the duration of mechanical ventilation, the length of stay in the intensive care unit (ICU), recovery of consciousness and the mortality. Results: New infections developed in 46.7% of the patients. Asystole was the most common rhythm (70.7%). The most common infectious complication was pneumonia (40.0%) urinary tract infection developed in 10 cases, vascular catheter local infection developed in 6 cases, primary blood stream infection developed in 3 cases, wound infection developed in 2 cases and pseudomembranous colitis developed in 1 case. The most common pathogens of pneumonia were Pseudomonas aeruginosa and Staphylococcus aureus. Blood cultures were obtained in 36 patients during the first 24 hr and the pathogen was isolated in three. The patients with infection had a longer duration of mechanical ventilation and a longer stay in the ICU (p<0.001, p=0.001). Conclusions: Infectious complications are common in survivors of out-of-hospital cardiac arrest and these infections are associated with a longer duration of mechanical ventilation and a longer stay in the ICU. The most common infectious complication was pneumonia and the pathogens of pneumonia were Pseudomonas aeruginosa and Staphylococcus aureus.
禹仙熙,鄭丞根 충북대학교 농업과학기술연구소 1989 農業科學硏究 Vol.7 No.2
In order to elucidate the effects of seeding time on growth and competition ability of common purslane(P.oleracea L.), sowings were made at five different dates in 1/2, 000 a pots in 1988. : As the sowing date delayed, plant height and number of branches were increased due to promoted early growth, and as planting densities were increased they were reduced by the intra - species competition regardless of sowing date. Effect of sowing date on dry weight of common purslane had the same tendency as plant height and number of branches, and dry weight per plant was decreased rapidly upto 4 plants/pot by increased planting density, but showed lower decreasing degree above 4 plants/pot. Changes of dry weight were affected by planting density and total dry weight per plant was not significantly affected by planting density. Seed productivity of common purslane per plant was decreased as planting density was increased, and seed productivity per pot showed same tendency affected by number of plant regardless of planting density. In inter - species competition with soybean, growth of common purslane had a same tendency as only commonpurslane was grown, growth degree and effect of planting density were low. Growth and yield of soybean showed differences between sowing date only and was not affected by intra - species competition in common purslane while interspecies competition ability of common purslane to soybean appeared to be low.
범죄 피해 불안과 인구사회학적 요인: 유럽국과의 비교를 중심으로
우선희 한국보건사회연구원 2018 보건복지포럼 Vol.261 No.-
개인의 불안은 개인의 삶의 질에 영향을 미칠 뿐만 아니라 대인관계나 사회활동에도 영향을 미쳐 사회적 문제로 이어질 가능성이 높다. 그런데 이러한 불안은 주관적인 느낌으로, 각 개인이나 사회의 객관적인 지표와 항상 상응하여 나타나지는 않는다. 이 글에서는 범죄 피해 불안에 대한 인구사회학적 요인에 따른 분석을 통해 어떤 사람들이 더 불안한지, 불안에 국가 간 차이가 있는지를 검토하고자 하였다. 분석 결과, 한국은 전반적으로 범죄 피해 경험률이 낮음에도 불구하고 범죄 피해에 대해 불안을 느끼는 사람의 비율이 상대적으로 높게 나타났으며, 유럽 비교 대상 국가와 상반되게 교육 수준이 높고 연령이 낮은 계층에서 불안을 느낄 가능성이 높게 나타났다. 그러나 사회적 자본 및 대인 신뢰도의 제고는 한국에서도 불안을 낮출 수 있는 유의미한 요인임이 확인되었다.
Excitatory Effect of M1 Muscarinic Acetylcholine Receptor on Automaticity of Mouse Heart
우선희,이병호,권광일,이진옥 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.8
We have investigated the effects of relatively high concentration of carbachol (CCh), an agonist of muscarinic acetylcholine receptor (mAChR), on cardiac automaticity in mouse heart. Action potentials from automatically beating right atria of mice were measured with conventional microelectrodes. When atria were treated with 100 μM CCh, atrial beating was immediately arrested and diastolic membrane potential (DMP) was depolarized. After exposure of the atria to CCh for ~4 min, action potentials were regenerated. The regenerated action potentials had lower frequency and shorter duration when compared with the control. When atria were pre-exposed to pirenzepine (1 μM), an M1 mAChR antagonist, there was complete inhibition of CCh-induced depolarization of DMP and regeneration of action potentials. Pre-exposure to AFDX-116 (11({2-[(diethylamino)-methyl]-1-piperidyl}acetyl)-5,11-dihydro-6H-pyridol[2,3-b][1,4] benzodiazepine-6-one base, 1 μM), an M2 mAChR antagonist, failed to block CCh-induced arrest of the beating. However, prolonged exposure to CCh elicited gradual depolarization of DMP and slight acceleration in beating rate. Our data indicate that high concentration of CCh depolarizes membrane potential and recovers right atrial automaticity via M1 mAChR, providing functional evidence for the role of M1 mAChR in the atrial myocytes.