국민학교아동의 성교육에 관한 연구

고정자,신영란 東亞大學校 附設 生活科學硏究所 1995 생활과학연구 논문집 Vol.3 No.-

The purpose of this study is to make some valuable suggestions on sex education for elementary school pupils. The study is interested in the following questions: First, what about the state of sexual maturity of elementary school pupils and what difference is made according to such variable like grade, sex, residential environment, social and economic position, etc.? Second, what about the state of the young pupils' consciousness of the apposite sex and what difference is shown according to the variables? Third, what opinions do the parents and teachers have on sex education and what difference is there according to the variables (sex, age, educational background and teaching career)? For this study questionnairs were distributed to 955 elementary school pupils, 310 elementary school teachers, and 333 parents of the pupils living in Pusan. The answers of each section of the questionnairs returned were analyzed by ?? examination for the representation in terms of percentage. The findings of the investigation are as follows. First, at an earlier period than before do the pupils experience wetdream and menarche, the girls' breasts swell and the boys' voices change, and their pubic and armpit hair grow. That is ther is a tendency of early sexual maturity among young boys and girls owing to the improvement of their constitution through the betterment of the diet. Second, it is brought out that the reason young boys and girls have much interest in associating with the opposite sex is for the change of their consciousness of the opposite sex because of psychological development, influenced by various kinds of mass media. Third, it is shown that all the parents and teachers recognize the necessity of sex education at the elementary schools. They think that it would be good for teachers to teach pupils in the and fifth and sixth grade in relevant classes and for parents in special classes. They think that it would be good for them to teach the pupils about the differences and the roles of man and woman, the phenomena of sexual physiology, sex morals and hygiene in that order.

국내산 무화과를 이용한 와인 제조 및 품질 개선 효과

정미란,차정단,윤순일,한종현,이영은 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.1

Fig(Ficus carica L.) which belongs to Moraceae family has been used as digestion promoter, cure for ulcerative inflammation and eruption in Korea. Figs have very short preservation period and can be kept only 1 week even in the refrigeration system. The possibility of wine-making from Korean figs was tested by analyzing the fermentation characteristics, proximate analysis and free sugar contents of wine made of slices with 20% sugar addition. Ethanol fermentation of the figs by Saccharomyces cerevisiae was done rapidly. The ethanol contents, pH, total acidity and sugar content were 12.1%, 3.91, 0.42% and 9.9 °Brix, respectively. The results from the sensory evaluation were as follows. The wine made from the sliced figs were better than that from fig juices in their sensory scores. The wine made with frozen figs was not different from that made with fresh ones. To improve the quality of wine, the addition of dried leaf powder in the concentration of 100 ppm were tried and found it was superior to the one made without leaf.

악골에 발생한 악성 섬유성조직구종 2례

정종철,최홍란,오희균,박준아,류선열,이종호,김영운,정숭룡 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

Malignant fibrous histiocytoma rarely occurs in the jaws. Although the histogenesis of this tumor remains controversal, it is best regarded as a primitive and pleomorphic nature reflected by collagen production and occasional phagocytosis. It is common for metastatic foci to appear in lung and regional lymph node. There are variable treatments such as radiotherapy, surgical excision or combination, therapy of surgical excision, chemotherapy and radiotherapy. With the review of literatures, the authors report the clinical study of two cases of malignant fibrous histiocytoma of the jaw.

국내산 무화과의 식중독균에 대한 항균활성

정미란,차정단,이영은 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

The antibacterial activities of methanol extract and systematic solvent fractions(-hexane, chloroform, ethyl acetate, and butanol) from Korean common type figs at different ripening stages were tested by the broth dilution method against 8 representative food-poisoning bacteria- : L. monocytogenes, S. aureus, S. enteritidis, E. cols 0157:H7, E. cols, Y. enterocolitico, V. parahaemolvticus, and S. ttphimurium. The methanol extracts of unripened Ⅰ and Ⅱ showed stronger activity than that of the ripened figs especially against L. monocytogenes, S. enteriridis, E. toll 0157:H7, V. parahaemolvticus and S. nphimurium in 10 mg/mL. The systematic solvent fractions showed stronger antibacterial activities than the methanol extract, even at the lower concentrations. The hexane fraction of ripened Figs showed higher growth inhibition than those of unripened Ⅰ and Ⅱ against L. monocytogenes, E. colt 0157.117, Y. enterocolitica and V. parahaemolvtieus. The chloroform fraction showed strong antibacterial activity in all ripening stages against E. soli 0157:H7 and V. parahaemolyticus. The butanol fraction showed better inhibition activity in unripened I and II than in the ripened figs. The hexane and chloroform fractions showed inhibition activity of more than 75% against E. coli 0157:117, V. parahaemohvicus in 0.5 mg/mL. Each fraction showed a little different antibacterial activity according to the ripening stages of the fruits and the tested strains. Especially, rigs in the unripened II stage revealed superior activity relatively and the hexane and chloroform tractions revealed the strongest activity, followed by the butanol fraction, while the ethylacetare and water fractions hardly showed any activity.

The effects of antibiotics on the reproductive physiology targeting ovaries in the Asian tiger mosquito, Aedes albopictus

Ha Young‐Ran,Jeong Se‐Jin,Jang Chang‐Won,Chang Kyu‐Sik,Kim Hyun‐Woo,Cho Shin‐Hyoung,Lee Hee‐Il 한국곤충학회 2021 Entomological Research Vol.51 No.2

Mosquitoes have adapted to various environmental conditions. Symbionts with mosquitoes impact this adaptation in different environments. In the field, mosquitoes could get exposed to antibiotics during their developmental period, which could reduce or eliminate their symbiotic microbes. However, the side effects of the antibiotics on the ovary and reproductive physiology of the Asian tiger mosquito, Aedes albopictus remains unknown. In this study, we investigated the effects of tetracycline and combinations of rifampicin and tetracycline at environmentally acceptable levels on the reproductive physiology of ovaries in Ae. albopictus. Rifampicin and tetracycline in combination reduced the hatching rate and fertility of Ae. albopictus compared to the untreated control group. These antibiotics induced histopathological damage and reactive oxygen species production in the ovaries. The combination of antibiotics decreased the expression of surface protein of Wolbachia (WSP) in Ae. albopictus. Additionally, the expression of Toll like receptor 2 (TLR2) and Myd88 were triggered by the combinations. The findings demonstrate the detrimental effects of antibiotics, particularly combinations of rifampicin and tetracycline, on the reproductive capacity of Ae. albopictus females.

셀레콕시브 및 그 합성유도체들의 항암활성 스크리닝

박정란,강진형,구효정,노지영,류형철,박상욱,고동현,조일환,이주영,황다니엘,김인경 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

Selective COX (cyclooxygenase)-2 inhibitors including celecoxib have been shown to induce apoptosis and cell cycle changes in various tumor cells. New inhibitors are recently being developed as chemomodulating agents. We evaluated celecoxib and screened 150 synthetic compounds for anti-proliferative activities in vitro. Effects of celecoxib on COX activity, cell growth, cell cycle distribution, and apoptosis induction were determined in A549 COX-2 overexpressing human non-small cell lung cancer (NSCLC) cells. The COX inhibition of celecoxib increased with concentration up to 82% at 1μM after 24 hr exposure. Forty μM and 50μM of celecoxib induce G_1 arrest, and TUNEL-positive apoptotic cells, respectively. Among 150 compounds, several compounds were selected for having greater COX-2 inhibitory activity and higher selectivity than celecoxib with growth inhibitory activity. Celecoxib showed concentration-dependent COX inhibitory activity, and ability to induce cell cycle arrest and apoptosis in human NSCLC cells in vitro. Among synthetic analogues screened, several compounds showed promising in vitro activity as COX-2 inhibitory anticancer agents, which warrant further evaluation in vitro and in vivo.

MPEG-21 표준의 구현을 위한 Testbed 구축

손정화,손현식,조영란,권혁민,김만배 강원대학교 정보통신연구소 2003 정보통신논문지 Vol.7 No.-

1990년대 후반부터 다양한 디지털 통신망을 이용하여 멀티미디어 컨텐츠 서비스가 가능하게 되었다. 하지만, 멀티미디어 컨텐츠의 전달 및 이용을 위한 기반 구조들의 독자적 발전 및 다양한 통합적 관리 체계 시스템으로 인해, 멀티미디어 컨텐츠 표현 방식의 호환성 문제, 혼재하는 네트워크 전달 방식과 단말 방식의 호환성 문제 등의 잠재적인 문제점이 발생한다. 이런 문제의 대안으로 현재 존재하는 기술 및 기반 구조들 사이의 연동을 통한 큰 프레임워크인 MPEG-21이 진행 중이다. 본 논문에서는 현재 표준화 작업이 진행 중인 MPEG-21을 기반으로 하는 Testbed를 제안한다. Testbed는 server, client, DIA(Digital Item Adaptation)의 세 모듈로 구성된다. Server의 역할은 멀티미디어 컨텐츠를 Digital Item(DI)으로 생성하고, client가 DI를 요구할 경우 DIA 모듈을 통해서 변환된 DI를 client에게 제공한다. DIA 모듈은 server에서 동작되며 client로부터 요청된 DI를 분석하고 client로부터 전송된 환경 정보를 이용하여 client 환경에 적합하게 변환된(adapted) DI를 생성하는 것이 주 기능이다. Client는 server에 저장되어 있는 DI를 선택하고 user preference, terminal capability 등의 필요한 정보를 server로 전송한다. Testbed에서는 스포츠 경기의 동영상, 정지 영상, 경기 내용, 역사를 기록한 파일 등의 DI를 이용한다. 표현 언어는 XML이며, HTTP 기반의 Web 환경에서 구동되도록 설계된다.

어린이가 선호하는 치과 의료진의 복장에 대한 연구

남정란,이난영,이상호 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.2

어린이 치과 진료 시 진료에 도움을 얻고자 연구한 설문지조사 시 진료진들의 복장에 대한 선호도에 응한 650명의 어린이에 치과 진료진들에 대한 선호도에서 다음과 같은 결과를 얻었다. 1. 남 여 치과의사의 복장으로 정장가운과 일상복 중 전반적으로 정장가운을 대상자의 특성별로 남자 67.7~87.6% 여자 59.2~75.9% 선호하였다. 2. 남자 치과의사의 정장가운 중 전형적인 흰색 긴가운을 가장 선호하였으며 일반 긴가운, 짧은 자켓이나, 짧은 수술복 순으로 선호하였다. 3. 여자 치과의사의 가운 중 전형적인 흰색 긴가운을 가장 선호하였으며 일반 긴가운, 짧은 자켓가운, 짧은 수술복 순으로 선호하였다. 4. 치과위생사의 가운에 대한 선호도에서는 투피스 바지에 대한 선호도가 높았으나, 원피스, 투피스 치마, 만화 캐릭터, 에이프런 가운에 대한 선호도의 차이는 크지 않았다. 5. 가운의 색에 대한 선호도에서는 흰색에 대한 선호도가 높았다. 6. 가운의 무늬에 대한 선호도에서는 전형적인 형태의 민무늬에 대한 선호도가 높았다. The purpose of this study was to find a method for improving children's preferences during dental treatment in relation to dentist's attire. For this study, 650 children asked to participate in a survey about the attire of the dentists. The results of the survey were as follows: 1. The survey found that gowns were preferred to ordinary clothes for both male and female dentists, 67.7 to 87.6% for male and 59.2 to 75.9% for female dentists. 2. For male dentists, the typical long white gown was the most preferred style, followed by a long town, and a short jacket type, and then a short operating gown. 3. For female dentist, the typical long white gown was also most preferred, followed by a long gown, a short jacket type, and then a short operating gown. 4. For dental hygienists, the most preferred attire style was a two-piece wear with pants, followed by one-piece, skirt suit, shirts with cartoon characters, and apron. However, the difference among these attires was insignificant. 5. White was the preferred color for gown. 6. Children prefer gown with no-pattern.

정상면역을 가진 환자에서 발생한 복부대동맥의 진균 감염성동맥류 1예

이호영,김태형,추은주,전민혁,이은정,정은정,전성란,박의주,염욱,장원호,황정화,김동훈,김동원 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

감염성동맥류는 드물지만, 치명적인 질환이다. 진성 진균성 감염성동맥류는 더 드물게 발생한다. 진균감염은 사망률과 이환율이 매우 높다. 그러나 증상이 비특이적이고 일반적인 진단방법으로는 민감하게 진단이 되지 않기 때문에 종종 진단이 어렵다. 저자들은 면역이 정상이고 다른 위험인자가 없는 환자에서 복부대동맥에 발생한 진균성 감염성동맥류를 경험하여 이를 보고한다. 컴퓨터 단층촬영과 혈관 수술에 기초하여 진단하였으며, 수술 후 조직배양에서 균이 동정되지는 않았으나 절제한 혈관조직에서 칸디다 감염을 시사하는 발아가 있는 효모균이 관찰되었다. 한국에서 1988년에서 2007년까지 복부에 발생한 감염성동맥류 17증례를 고찰하였을 때 진성 진균성 감염성동맥류는 없었으며, 저자들이 경험한 것이 복부에서 발생한 진균감염성 동맥류로는 첫 증례이다. Infected aneurysms are uncommon, frequently fatal lesions. "True" fungus-infected aneurysms are even rarer. Fungal infections have high morbidity and mortality. However, diagnosis is frequently difficult, since the symptoms are non-specific and standard diagnostic procedures are often insensitive. We experienced a patient with persistent fever and negative blood cultures. The patient was immunocompetent and had no risk factors, and was diagnosed with a fungus-infected aneurysm based on computed tomography and vascular surgery. The vascular tissue revealed some narrow-based budding yeast within the thrombus, suggesting Candida infection. Seventeen cases of infected aneurysm of the abdomen were reported in Korea from 1988 to 2007, although none were "true" fungus-infected aneurysms, making this the first fungus-infected aneurysm of the abdomen in Korea. Prompt diagnostic procedures and aggressive treatment modalities are necessary for patients with occult infection and negative blood cultures, regardless of their immunocompetence, because of the high morbidity and mortality of this condition.

전분 종류를 달리한 무화과편의 품질 특성

김병숙,정미란,이영은 한국조리과학회 2003 한국식품조리과학회지 Vol.19 No.6

The effects of various kinds of starch (mungbean, potato, corn, and a blend of potato and corn starch) on the quality characteristics of muhwakwa-pyun were studied according to the storage duration. The sweetness, pH and total acidity of muhwakwa extract were analyzed, as were the Visco/Amylograph viscosity profile and DSC thermodynamic characteristics of starches. For quality characteristics, color difference, instrumental texture characteristics and sensory characteristics were compared. The sweetness of muhwakwa extract was satisfactory but the total acidity was low for Kwa-pyun manufacture. Therefore, its pH was adjusted to 3.4 by adding 10% citric acid with an amount of 1% of total liquid. From the Visco/Amylograph viscosity profile and DSC thermodynamic characteristics of starches, a blend of potato and corn starch was found to be easy to cook and form a gel but a 1ittle more resistant than the other starches in terms of retrogradation. Lightness (L) and yellowness (b) of Kwa-pyun increased while its redness (a) decreased by the storage. The color became whiter and the clarity decrease regardness of the kinds of starch, which became obvious after 3 days of storage. The hardness, springiness, adhesiveness and cohesiveness tended to decrease with storage, which was weak in a blend starch. The overall acceptability of Kwa-pyun made with a blend of potato and corn starch was evaluated as being the best among the samples tested. Therefore, for traditional kwa-pyun manufacture mungbean starch might be replaced with a blend of potato and corn starch which is less expensive and easily available in the market nowadays.