전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

충북 남부지역 중소 제조기업의 경쟁력 제고를 위한 경영 및 애로기술 실태조사 연구

윤상원,구경완,정성진,백기영,김선훈,서용성,이근복 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

본 연구에서는 충북 남부 3개군 지역(옥천 · 보은 · 영동)의 중소 제조기업의 경영실태 및 애로기술을 대상으로 실증조사 되었다.·지역의 특정상황의 전제하에 지방 중소기업들의 실질적인 문제점들을 발견하고, 그 개선 방안을 탐색함은 물론 산 · 학 · 연 컨소시엄 사업의 성공적인 수행을 위해 시도되었다.세부적으로는 중소 제조기업의 경영 및 애로기술 특성을 일반적 사항, 경영애로요인, 경영전략, 현장개선기법, 정보화, 제품 및 공정 기술상의 애로기술 현황파악의 6개 영역으로 조사되었다. 조사결과들은 추후 산 · 학 · 연 공동기술개발 사업에 있어 창의적, 틈새적 과제발굴 및 신제품 기술개발의 토대마련이 될 뿐 아니라, 지역경제 발전을 위한 산 · 학 관의 지원 전략 수립에 적극 활용 될 것으로 판단된다.

그래픽 프로그래밍 언어와 가상 인스트루먼트를 이용한 네트웍 기반 실시간 실험실 자동화 시스템의 설계

윤근수,정원영,박영석 경남대학교 공업기술연구소 2000 硏究論文集 Vol.18 No.-

오늘날 개인용 컴퓨터와 네트웍의 발전과 함께 가상 인스트루먼트는 프로세스 자동화, 공장 자동화, IC패킷 테스트, 데이터 획득, 실험실 자동화, 기계 컨트롤 등의 광범위한 자동화 영역에 사용되고 있다. 가상 인스트루먼트는 네트웍을 통한 개방구조로 원격지에서 제어 및 모니터 링을 제공하며, MMS (Modular Measurement System)와 재사용 가능한 컴퓨터 프로그램 모듈을 이용하여 시스템의 개발 및 유지 보수가 용이해서 비용을 줄일 수 있다는 장점을 가지고 있다. 본 논문에서는 그래픽 프로그래밍 언어인 HP VEE(Hewlett Packard Visual Engineering Environment)와 가상 인스트루먼트를 이용하여 네트웍 기반 실시간 실험실 자동화 시스템을 효과적으로 디자인하는 방법을 제안하였고, 초전기(Pyroelectricity)현상을 측정하는 시스템에 적용하여 전형적인 시스템 디자인에 비하여 효과적인 결과를 얻었다. In the present, because of the developments of the personal computers and the communication networking technologies, VI (virtual instruments) is getting popular and useful in the fields of the automatic processings and controls, IC packet test, factory automation, DAQ(data acquisition), laboratory automation, and machine control etc. VI System provides the control/ monitoring measurement processes from the remote location, the open structures by networking, an easy maintenance and inexpensive developments using MMS (modular measurement system), and the usability of a numerous reusable computer program module. In this paper, we propose a method to design network-based real-time laboratory automation system using the graphic programming language, HP VEE (Hewlett-Packard Visual Engineering Environment), and virtual instruments. Then for the pyroelectricity measurement system, the proposed system gives more effective results than the conventional system based on the processing times and utilities.

디지털 위서 통신 채널의 비선형성 보상을 위한 신경회로망 등화기의 설계 및 평가

윤병문,김정희,임영선,진근식,신요안 崇實大學校 生産技術硏究所 1995 論文集 Vol.25 No.2

A digital satellite communication channel has a strong nonlinearity with memory due to saturation characteristics of the high power amplifier in the satellite and transmitter/receiver filters used in the overall system, and can be well modelled by a nonlinear Volterra series. In this paper, we design and evaluate neural network based adaptive equalizers for compensation of nonlinearities in digital satellite communication channels. We consider CMLP (complex multi-layered perception). CRBFN (complex radial basis function network) and complex ρth order Volterra filter as equalizers, and evaluate their performances in terms of symbol error rate under various noise conditions. In particular, a complex hybrid learning algorithm of k-means clustering and LMS (least mean squares) algorithm is proposed for the CRBFN. Computer simulation results show good performance for all the equalizers considered

HBeAg 양성인 만성 간염에서 라미부딘 치료전 HBV Core Promoter 서열이 약제내성 발생에 미치는 영향

윤영근,김연수 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

<Background> Lamivudine is a potent inhibitor of RNA-dependent DNA polymerase of HBV. However its efficacy is limited by emergence of drug-resistant mutant. Mutation of HBV core promoter (CP, T1762 and A1764) is known to be associated with the reduction of transcription of precore mRNA and development of HBeAg-negative phenotype. Therefore, it could be assumed that the CP sequence might influence the responsiveness to antiviral therapy such as lamivudine in HBeAg-positive chronic hepatitis B. This study was carried out to find out if pretreatment CP sequences are associated with the development of lamivudine resistance in HBeAg-positive chronic hepatitis B. <Method> HBV CP sequences were analysed directly from the pretreatment sera of eight patients in whom high level of HBV DNA breakthrough occurred during the treatment, which were compared to those from eight patients who cleared HBeAg without the breakthrough. HBV polymerase sequences were also analysed in the patients with the breakthrough. <Results> Serum HBV DNA level who had the breakthrough was 2653±1459 pg/mL and 1405 ± 403 pg/mL in the patients who cleared HBeAg. All the patients with DNA breakthrough showed YMDD mutation (4 with Met552Val and Leu528Met and 4 with Met550Ile). Among the patients with the breakthrough, baseline CP sequence was wild type (A1762, G1764) in three, A1762 and A1764 in three, and T1762 and A1764 in two patient. On the other hand, among the patients who cleared HBeAg, seven patients(88%) haboured T1762 and A1764 mutation(p=0.018) at pretreatment period. Remaining one patient had wild type CP (A1762, G1764), however precore mutation(A1896) was found in this patient. <Conclusion> It is likely that emergence of lamivudine-resistant mutant or HBeAg seroconversion is influenced by the baseline HBV CP sequence in HBeAg-positive chronic hepatitis B.

편평 사마귀

윤상노,김영근 한국의학사 1993 診斷과治療 Vol.13 No.3

에어로빅운동이 호흡순환기능과 혈중지질에 미치는 영향

윤영복,박병근,정동혁 圓光大學校 附設 體力科學硏究所 2005 體力科學硏究 Vol.28 No.-

The purpose of this research is to examine the effect of the aerobic exercise duration on cardiorespiratory function and blood lipids. Total 14 divided into two groups 7, for the control group and the other for the experimental group 7. The subjects of experimental group had 8 weeks aerobic program in the given intensity, during which the changes in cardorespiratory function to body fat and blood lipids were measured three times, at each end of 8th, 8th week. The research is concluded as follows. 1. After 8 Weeks, aerobic exercise brought the decrease of maximum HR with statistically significant(p<.05). 2. After 8 Weeks, aerobic exercise brought the increase of VE with statistically significant(p<.05). 3. After 8 weeks, aerobic exercise reduced TG, LDL-C and T-C with statistically significant(p<.05). In conclusion, aerobic exercise helps overweight women to reduce their weights and the amount of fat and to get rid of elements that cause various geriatric diseases. Therefore, overweight women as well as common adults are advised to take aerobic exercises.

1998년도 신입생 실태조사 연구

윤영식,남근숙 순천대학 학생생활연구소 1998 學生生活硏究 Vol.17 No.-

내연기관 흡기 계통의 Plenum Chamber의 유동 해석 모델에 관한 연구

윤건식,윤영환,우석근 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

In this paper, the simulation models were examined to represent the flow through the plenum chamber in the intake system of MPI spark ignition engine. The constant-pressure perfect-mixing model or branch model which had been devised originally to represent the flow through the manifold branch system was tested. The constant-volume model or tank model also applied and the results were compared with those of the branch model. The prediction accuracies showed no remarkable differences between two models. Therefore, both models would be applicable successfully to represent the flows at the plenum chamber.

부산시 지가와 기능공간 분포특성

윤철현,황영우,전호근 동아대학교 건설기술연구소 1997 硏究報告 Vol.21 No.1

This paper has tried to get hold of spatial distribution of land value in Pusan and an influence of land value on the various kinds of urban functions. Conclusions by the research are as follows. First, points of peak land value in Pusan are Kwangbok-Dong and Bujeon-Dong, and Kwangbok-Dong is greater than Bujeon-Dong in the influential zone according to just spatial present condition of land value. Second, specialized functional agglomeration and regional differentiation functionally are explicit in the region of Kwangbok-Dong. Third, functions having great correlation with land value are high quality retail, food and entertainment, cultural, and service function. Finally, functions having interdependent relation with many other ones are official, food and entertainment, service, and cultural function.