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Jin Tae Hong, Dohee Won1, Mi Hee Park, Sun Mi Kown, Miran Jo, Sang-Yoon Nam, Beom Jun Lee, Young Won Yun, Ki-Wan Oh, Sang Bae Han 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.4
The objective of this study was to determine the effect of macrophages on growth of human colon cancer cells. The results showed that co-culture of colon cancer cells with macrophages inhibited the growth of colon cancer cells (HCT116 and SW620) depending on the number of macrophages, RAW 264.7 cells, and activated THP-1 cells accompanied by down regulation of pSTAT3 in cancer cells. We also found that expression and release of cancer cell growth inhibitory cytokines, IL-1 receptor antagonist (IL-1ra) and IL-10, was increased in macrophages. Blocking of the STAT3 pathway with specific inhibitor and siRNA of STAT3 abolished the growth of colon cancer cells and expression of IL-1ra and IL-10. In addition, neutralization of IL-1ra and IL-10 with antibodies resulted in reversal of macrophage-induced inhibition of cancer cell growth. These data showed that IL-1ra and IL-10 released from macrophages inhibit growth of colon cancer cells through inhibition of the STAT3 pathway
한지 쌈지 극미량 고체상 추출법을 이용한 레몬과 오렌지 향유 성분 분석
원미미,이동선 서울여자대학교 2010 자연과학연구논문집 Vol.22 No.-
In this study, headspace mulberry paper bag micro solid phase extraction (HS-MPB-μ-SPE) combined to gas chromatography/mass spectrometry has been applied for the analysis of volatile aromas of liquid essential oils from lemon and orange. The technique uses an adsorbent of Tenax TA contained in a mulberry paper bag, minimal amount of organic solvent and very small amount (10 μL) of sample size. Linearity for the calibration curve was excellent, the LOD value was 10.3 ng/mL. Precision and recovery were generally good. In addition, this method allowed combining extraction, enrichment, and clean-up in a single step. Analysis of aroma components in lemon and orange essential oils were performed successfully using this method.
SPME와 GC/MS를 이용한 녹나무 향기성분 특성분석
원미미,차은주,윤옥경,김남선,김건,이동선 서울여자대학교 자연과학연구소 2007 자연과학연구논문집 Vol.19 No.-
Recently, land managers have come to realize that, outside Asia, camphor trees grow like street-tree or weeds, infesting forests and displacing native trees. This is because camphor trees are prolific seed producers that do not have serious predators or diseases outside their native range. The camphor tree (Cinnamomum camphora), belongs to lauraceae, is the aromatic evergreen tree from which camphor was derived. Headspace solid-phase microextraction (HS-SPME) and GC-MS were applied for the analysis of volatile fragrances emanated from camphor tree. Divinylbenzene / Carboxen / PDMS fiber was used for HS-SPME adsorption materials. (+)-Camphor (31.00%) and cineol (21.89%) were found as the major volatile aroma components from Chinese camphor tree, whereas (+)-camphor (62.06%) and β-caryophyllene (10.01%) from Japanese camphor tree. Camphor tree is a promising garden tree for well-being.
개에서 발생한 양파 섭취에 의한 하인즈 소체 용혈성 빈혈 증례
이미선,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1
A 10 month-old Yorkshire Terrier was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of lethargy, bile pigment in urine and anorexia. Blood smear showed Heinz body, polychromatocytosis, schistocytosis, anisocytosis, which were the results from the oxidative injury. Hematology demonstrated a moderate anemia(PCV 22.4%, reference rage 35-55%), which was regeneration based on the degree of RPI (4.03, reference rage > 1). Serum biochemistry demonstrated mild elevation in total bilrubin, and mild decrease in total protein and albumin concentration. A diagnosis of Heinz body hemolytic anemia secondary to onion ingestion was made and treated with fluid therapy, oxygen and antioxidant drugs. The dog recovered without any complication.
한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고
최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1
The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.
권선옥,박선미,장순영,전혜숙,정원혜,최혜옥 효성여자대학교 가정대학 학도호국단 1984 家政大論集 Vol.3 No.-
We estimated fingernail nitrogen content from children in a city, a farm village, a mountain village and a fishing village. Therefore, the result is as follow. In summer, nail nitrogen content was estimated 130.79±15.39mg/g in a city, 123.86±24.93mg/g in a farm village, 96.16±17.04mg/g in fishing village, 91.96±6.76mg/g in a mountain village. In winter was estimated 137.43ㄷ69.06mg/g in a city, 131.70±8.49mg/g in a farm village, 124.75±16.34mg/g in a fishing village, 115.81±6.36mg/g in a mountain village. According to this analysis, the nail nitrogen content lowered by turns a city, a farm village, a fishing village, a mountain village. The nitrogen contents of nails obtained in winter were found to be higher than those obtained in summer.
윤미향,정미선,박원혁 부산대학교 사범대학 과학교육연구소 2007 科學敎育硏究報 Vol.34 No.-
The purpose of this study was to find out the difference of decision-making process based on the nature of science. The contemporary and traditional point of view group regarding the nature of science were composed and provided socio-scientific issues. Also, the decision-making process questionaries and interview about socio-scientific issues were conducted to groups. The decision-making process questionary was consisted of five steps : identification of problem, searching alternatives, generation of alternatives, analysing alternatives, and selecting alternative. The results of this study showed at the both groups' decision-making process was difference in the first four steps: the one who has contemporary point of view recognized the various conflict situation, searched the objective informations, applied a diverse of standards, and found the concert solution but the other recognized conflict situation fragmentarily, searched the subjective informations, applied limited standards, and found the realizable solution. The result to the final step, selecting alternatives, were similar in both groups because they didn't suggest the rational reason for selecting alternatives. so, it request the long terms of decision-making experience to make rational decision regardless of the nature of science.
차미선,소원욱,박인준,이수복 한국공업화학회 2004 응용화학 Vol.8 No.1
We describe the synthesis and characterization of amphoteric poly(acrylate), consisting of the F-marcromer and a 2-(dimethyl amino)ethyl methacrylate (2-DMAEMS) The amphoteric polymer were prepared by marcromonomer technique and radical copolymerization. After copolymerization, the resultant rection solution was purified by silica column. In this study, separation of resultant reaction sloution was purified by silica column. In this study, separation of amphoteric poly(acrylate)s and characterization by InfraRed Spectroscopy, Gel Permeation Charomatography. The IR traces showed that the amphoteric poly(acrylate) was separated successfully polymr of p(2-DMAEMA). The amphoteric poly(acrylate) have number average molecular weights(Mw) about 38,000 by GPC.