시험관내에서 당화시킨 인슐린의 생체내 활성

김성완,김성연,조보연,이홍규,고창순,민헌기,이문규,김철희,민용기,장학철,정대원,배철민 대한당뇨병학회 1990 Diabetes and Metabolism Journal Vol.14 No.2

수평방향의 정현파 가진을 받는 강체 블록의 비선형 로킹진동특성

김지훈,김정호,양인영,정낙규,정만용 한국산업안전학회 1999 한국안전학회지 Vol.14 No.4

This research concentrates on the influence of non-linearities associated with impact for the nonlinear rocking behavior of rigid block subjected to one dimensional sinusoidal excitation of horizontal direction. The transition of two governing rocking equations, the abrupt reduction in the kinetic energy associated with impact, and sliding motion of block. In this study, two type of rocking vibration system are considered. One is the undamped rocking vibration system, disregarding energy dissipation at impact and the other is the damped rocking system, including energy dissipation and sliding motion. The response analysis using non-dimensional rocking equation is carried out for the change of excitation parameters and friction coefficient. The chaos responses were discovered in the wide response region, particularly, for the case of high excitation amplitude and their chaos characteristics were examined by the time history, Poincare map, power spectra and Lyapunov Exponent of rocking responses. The complex behavior of chaos response, in the phase space, were illustrated by Poincare map. The bifurcation diagram and Poincare map were shown to be effective in order to understand chaos of rocking system.

신장이식 마취 5 예의 경험

정운혁,이상춘,박숙자,이병시,김성년,진수남 대한마취과학회 1970 Korean Journal of Anesthesiology Vol.3 No.1

This is a report of anesthesia for five cases of renal transplantation which was performed be tween February 1969 and August 1969 at St. Mary's Hospital, Catholic Medical College, Seoul, Korea. General of renal insufficiency of the operated cases were described. Operative technique were unilateral nephrectomy for three cases and bilateral nechprectomy with splenectomy for 2 cases ; Anesthesia was induced with epontol (propanidid) 250mgs i.v. and 4% halothane-oxygen and maintained with 1% halotbane-oxygen which was supplemented by nitrous oxide occasionally. 6% dextrose and lactated-Ringer's solution were infused. For transfusion, whole bleod was given to replace the operative blood loss. Dextran was also used to maintain adequate blood volume. Shortly before anastomosis of renal and femoral vessels, patients were haparinized. Fluids and electrolytes balance were studied pre-and post-operatively. Preoperatively, uremia and hyperpotassemia was corrected by several hemodyalysis. Urinary output after surgery showed a marked degree of diuresis up to 1800 ml/hr until second post-operative day. The special concern of anesthesia for kidney transplantation were: 1. Patients were suffering from severe uremia and metabolic disterbances. 2. Acidosis and hyperpotassemia should be corrected before surgery by hemo-or peritoneal dialysis. 3. Immunosuppressive agents made the patient less resistant to infection. 4. Anemia and hydrops was difficult to be corrected before surgery. 5. Muscle relaxants of choice were depolarizing agents, because of impaired renal excretion.

전신마취하에서 위액량과 pH 에 대한 임상적 고찰

김영석,김완식,박동호,정연탁,김미연 대한마취과학회 1979 Korean Journal of Anesthesiology Vol.12 No.4

In recent years, there has been renewed interest in preoperative methods to reduce gastric acidity, thus lessening the risk of a serious pulmonary reactions following aspiration of gastric contents. Emergency obstetrical patients frequently have large volumes of gastric fluid. It is less commonly appreciated that patients fasting prior to eleetive surgery afterive in operating room with large gastric fluid volumea with a low pH. Prophylactic preoperative oral administration of antacids hae been shown to reduce preoperative gastric aeidity.in significant percentage of patients, but aspiration of antacids can be associated with pulmonary complications, and there use may be associated with increased gastric volume. Preoperative adrpinistration of glycopyrrolate may decrease the frequency of surgicsl patients with a low gastric pH, and it appears that the volume of gastric fluid may be reduced by medication that relax the pylorus. However, none of thease pharmacologic manuevers completely abolisbes the possibility of serious pulmonary damage with aspiration. Mendelson and Teabeat demonstrated the importance of pH in the etiology of acid aspiration and it is generally accepted that the critical pH is 2. 5 or less, i.e. the risk of aerious pulmonary reaction increases progressively as the pH of the aspirate falls below 2.5. A critical voIume of acid aspirate is also neceasary for widespread pulmonary damage to occur irrespective of a low gastric pH. The critical volume is rhesus monkeys has been shown to be 0.4 ml/kg, but the critical volume in man is less well difined. Several investigators have determined the patient to be at risk of serious pulmohary complications with aspiration if at least 25 ml of gastric fluid with a pH of 2.5 or less is aspirated. The present study was undertaken to investigate the effects on the volume and pH of gastric juice under general anesthesia. The 35 patienta were studied, and were divided. into 4 group account to the kind of premedicants, N.P.O. time, weight, and obstetric patients Gastric juice, aspirated through a Levine tube, was examined for pH and. volume under general anesthesia.

저압용 누전차단기의 차단특성 및 그라파이트 분석에 관한 연구

정재희,이덕출,이경섭,최충석,박수홍,김병수 한국산업안전학회 1999 한국안전학회지 Vol.14 No.1

In this paper, we studied cut off characteristics and fire hazard of residual current protective devices(RCD or ELB) for low voltage. The operative time of RCD with grounding resistance was analyzed by using RCD operating tester. The surface structure and composition of insulator were analyzed by using scanning electron microscope(SEM) and energy dispersive x-ray spectroscopy(EDX). The surface of phenol resin showed network structure and void. The spectra shown in EDX analysis are composed not only of the corresponding elements but also of several new spectra, as CK, OKα , MgK, SiK, and CaK, which were absent in original material.

Mycobacterium Avium - in tracellulare Complex 와 M . Fortuitum 에 의한 폐항산균증(肺抗酸菌症) 3예

김상재,홍수표,배길한,김성진,진병환,정충모 대한미생물학회 1982 大韓微生物學會誌 Vol.17 No.1

Two cases of pulmonary disease in a 54 year-old female and a 70 year-old male patient due to Mycobacterium avium-intracellulare complex (MAIC) and a case of pulmonary infection in a 69 year-old male patient due to M fortuitum (MF) were found recently in this institute. All three patients bad a long history of anti-tuberculous chemotherapy because they were initially diagnosed as pulmonary tuberculosis. A 70 year-old male patient infected with MAIC had an unsuccessful chemotherapy history of isoniazid (INH), para-aminosalicylic acid (PAS) and streptomycin (SM) with an incomplete, temporary, symptomatic improvement, for three years since 1964 when he was first diagnosed as pulmonary tuberculosis on physical examination. A 54 year-old female patient infected with MAIC also had an unsuccessful chemotherapy history with the various anti-tuberculous drugs since 1958. Both patients discharged large number of MAIC in their sputum specimens for at least more than one year, but no M tuberculosis at all. A 69 year-old male patient infected with MF was diagnosed as moderately advanced pulmonary tuberculsis in 1977. Combined chemotherapy with INH+PAS+pyrazinamide (PZA) improved his clinical symptoms, however, his chest radiograph was deteriorated again in 1980 one year after he stopped therapy. Therefore he started chemotherapy again with INH+ethionamide (TH)+cycloserine(CS) but no improvement was noticed. MF was cultured from his sputum in August 1983 and he continuously discharged the same baeilli until last examination of January l982. Whether all three patients were initially infected with nontuberculous mycobacteria or complicated with predisposing tuberculosis was not clear because there were no reliable bacteriological Examination records.

연속주조법으로 제조된 Cu-9Ni-6Sn 합금의 기계적 특성에 관한 연구 : Part 1 . 연주속도 및 냉간 swaging 에 따른 기계적 특성 변화 Part 1 . Effects of Continuous Casting Rates and Swaging

류재철,김상식,김창주,정윤철,한승전 대한금속재료학회(대한금속학회) 1998 대한금속·재료학회지 Vol.36 No.8

In the present study, tensile properties of continuous casted Cu-9Ni-6Sn alloy, with and without 95% swaging, were examined as a function of continuous casting rates. A large amount of Sn-rich phases were observed in the interdendritic regions of as-casted Cu-9Ni-6Sn alloy, regardless of casting rates. The size and distribution of these phases, however, differ greatly with different casting rates, as well as the amount of Sn in the phase. Slower casting rate tended to increase the size of the phase, but the amount of Sn in the phase increased with faster casting rate. During solutionization, most of Sn-rich phase appeared to decompose into the solid solution. After aging, a significant amount of coarse precipitates were observed in the alloy produced at a casting rate of 280 ㎜/min. It is believed that such coarse precipitates were formed around the Sn-rich phases due to relatively high Sn content after solutionization. SEM fractographic studies indicated that coarse precipitates, as well as weak Sn-rich phases, act as sources for microvoid. Consequently, both tensile strength and elongation of solutionized and aged Cu-9Ni-6Sn alloy increased significantly with decreasing casting rate. Cold swaging greatly improved the tensile properties of Cu-9Ni-6Sn alloy due to the reduced and refined Sn-rich phases and coarse precipitates.

당뇨병성(糖尿病性)족부병변(足部病變)의 임상적관찰

이홍규,민헌기,이문규,정민화,원암우,김성연 대한당뇨병학회 1984 Diabetes and Metabolism Journal Vol.8 No.1

건식 열화처리가 FRP 의 표면 열화와 유전특성에 미치는 영향

이덕출,이백수,정의남,유도현,김종택 한국산업안전학회 1998 한국안전학회지 Vol.13 No.3

In this paper, we investigated the change of wettability, surface potential decay and dielectric properties caused by ultraviolet-treated, thermal-treated and discharge-treated FRP(fiber reinforced plastics) respectively for finding out: the influence of dry treatments effected to electrical characteristics on the surface of polymer composites. For the change of wettability, the contact angle of thermal-treated specimen with the high temperature of 200℃ increased. But that of UV-treated and discharge- treated specimen decreased. The characteristic of surface potential decay shows the tendency of the remarkable decrease on UV-treated and discharge-treated specimens, but no difference on thermal-treated specimen compared with untreated one. Also, for the dielectric properties, it shows the increase at large on the treated specimens and especially, the remarkable increase on thermal-treated one.

프럭토올리고당 및 유카 추출물이 육성비육돈의 성장 및 소화율에 미치는 영향

한인규,김진동,조원탁,이지훈,정원덕,김걸 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.6

본 연구는 프럭토올리고당 및 유카추출물이 육성-비육돈의 성장, 영양소 소화율 및 오염물질 배설량에 미치는 영향을 조사하기 위해 실시했다. 총 150두의 삼원교잡종(Landraceace × Duroc × Large White; 평균 개시 체중 21.88 ㎏ 육성기 및 61.07 ㎏ 비육기)을 사양 시험에 공시하였다. 각 돈방에 5두씩 수용하고 관행 사료로 3일간 적응시킨 후 (비육기에는 사료에 대한 적응기간을 두지 않음) 체중에 따라 5처리, 6반복, 반복당 5두씩 완전 임의 불럭 배치하였다. 처리구는 1) 대조구, 2) 0.3% FOS (사료내 프럭토 올리고당 0.3% 첨가), 3) 0.6% FOS (사료내 프럭토올리고당 0.6% 첨가), 4) 0.006% YE (사료내 유카추출물 0.006% 첨가), 5) 0.012% YE (사료내 유카추출물 0.012% 첨가)였다. 시험사료의 조성은 에너지 함량 3,320 ME ㎉/㎏, 성장단계별로 18.0%, 15% 및 13.5%의 조단백질 (CP)과 1.10%, 0.85%및 0.7%의 라이신을 각각 육성, 비육전기 및 비육후기사료로 급여하였다. 육성기간 동안 0.3% FOS 및 0.012% YE의 첨가는 일당중체량 (ADG) 및 일당사료 섭취량(ADH)에 유의한 영향을 미치지 않았다. 비육기에서도 FOS나 YE의 첨가에 의한 뚜렷한 성장률 개선효과는 발견되지 않았다. 한편 FOS의 경우 0.3% 첨가구보다는 0.6% 첨가구에서, YE의 경우 0.006% 첨가구 보다는 0.012% 첨가구에서 성장성적이 다소 우수한 경향을 나타냈으나 유의한 수준은 아니었다. 육성기동안 0.3% FOS와 0.012% YE 첨가구는 다른 처리구에 비해 조단백질과 조지방 소화율이 높게 관찰됐다. 비육전기에는 YE 0.006% 처리구에서 가장 우수한 성장을 보여 주었으며 비육후기에도 마찬가지로 YE 0.006% 처리구에서 가장 우수한 소화율을 나타냈고, FOS 0.3% 처리구에서 가장 낮은 소화율이 조사되었다. 도체성전에 있어서는 FOS 및 YE 첨가에 의한 효과는 나타나지 않았다. 돼지 1두당 총사료비용 (TFC) 및 ㎏ 중체당 사료비용 (TCG)은 모든 처리구간에 유의적인 차이가 나타나지 않았다. 본 실험에서 YE 및 FOS의 첨가로 인한 사료비용의 절감효과는 나타나지 않았으나 성장률 및 소화율 측면에서는 0.3% FOS 및 0.012% YE의 처리구가 우수한 경향을 보여 주었다. 육성기에는 FOS 및 YE의 첨가가 암모니아태 질소 함량에 유의적으로 영향을 미치지 않았으나 (P>0.05), 비육기에는 FOS 및 YE 첨가구가 대조구에 비해 암모니아태 질소 함량이 유의적으로 많아(P<005),이것은 분내 암모니아태 질소가 많이 발산되므로 돈사내 가스태 암보니아의 발산이 더 적다는 것을 설명한다. 본 시험의 결과를 종합해 볼 때, 육성·비육돈에 있어서 FOS 및 YE의 첨가는 성장능력, 영양소 소화율 및 도체성적에 대한 유의적인 개선 효과를 나타내지는 않았다. 그러나 FOS 및 YE의 첨가는 돈사내가스태 암모니아의 발산량 감소에 뚜렷한 효과를 갖는 것으로 판단해 볼 수 있다. This study was conducted to investigate the effects of fructooligosaccharide and yucca extract on the growth and nutrient digestibility in growing-finishing pigs. A total of 150 crossbred pigs (Landrace × Duroc × Large White ; 21.88 ㎏ and 61.07 ㎏ of average body weight for growing and finishing periods, respectively) were used in feeding trial. 5 pigs per pen were housed and adjusted to commercial diet for 3 days (no adaptation period for finisher period) and allotted into 5 treatments with 6 replicates per treatment with 5 pigs per replicate by a completely randomized block design. Treatments were 1) control, 2) 0.3% FOS (fructooligosaccharide), 3) 0.6% FOS, 4) 0.006% YE (yucca extract) and 5) 0.012% YE. The experimental diet supplied 3,320 ME ㎉/㎏, and different CP and amino acids by the live weight of pigs as 18.0%, l5% and 13.5% crude protein (CP), 1.10%, 0.85% and 0.70% lysine for grower, early finisher and latefinisher, respectively. During the growing period (Trial 1), 0.3% FOS and 0.012% YE treatments improved average daily gain (ADG) and average daily feed intake (ADFI), however there was no significant difference. Also, during finishing period, the supplementation of FOS or YE did not affect ADG, ADFI and FCR However, 0.6% FOS group showed the better performance than that of 0.3% FOS treatment, and 0.012% YE group showed an improvement when compared with 0.006% YE group. 0.3% FOS and 0.012% YE group were higher than the others in crude protein and fat digestibilities during growing period. During early finishing period, 0.006% YE group showed the highest digestibilities of dry matter, crude protein and fat among treatments, and significant improvement when compared with 0.3% FOS (p<0.05). During late finishing period, nutrient digesibilities were highest in 0.006% YE group and lowest in 0.3% FOS group. Carcass characteristics were not shown to be affected by the dietary group. No significant difference in backfat thickness was observed among dietary groups. In total feed cost (TFC) per head, and total feed cost per weight gain per head (TCG), there were no significant differences among treatments (p>0.05). 0.3% F0S group showed lower feed cost and better performance when compared to 0.6% FOS group. The supplementation of FOS and YE did not spare the feed cost. However, 0.3% FOS and 0.012% YE treatments showed better performance and digestibilities. Fructooligosaccharide and yucca extract did not affect the ammonia emission of pig significantly, however pigs fed 0.012% YE diet showed relatively higher ammonia-nitrogen emission during growing period, and pigs fed fructooligosaccharide or yucca extarct showed significantly higher (p<0.05) amount of ammonianitrogen emission, which means the lower gaseous ammonia production.