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서인수 대한미생물학회 1988 大韓微生物學會誌 Vol.23 No.1
In an effort to establish the role of new1y recognized as well as established agents of $lt;liarr- hca in Korean infants and children, 209 diarrheal children admitted to Hanyang University Hospital, Seoul, Korea, were evaluated during the course of 12 months. Stools were examined for Aeromonas hydrophila(Ah), Campylobacter jejuni(Cj), C.tostridium difficile(Cd), classic enteropathogenic E. cali(EPEC), enterotoxigenic E. coli(ETEC) and other enterotoxigenic gram-negative bacteria(GNB), enteroadherent E. coli(EAEC) and other Hep-2-adherent GNB, Salmonella, Shigella, and rotavirus(RV). One or more pathogens were identified in 70.3% of the children with diarrhea. RV was the most common pathogen, accounting for 51.2% of thecase, followed by ETEC(23.9%}, Cd(16.3%), EAEC(16.3%), EPEC(8.1%), heat-stable toxin-producing (ST') Klebsiella pneumoniae(1.9%), Hep-2-adherent K. pneumoniae(1.4%), ST^+ r1cinetobacter calcoaceticus var, anitratus(0.5%), Cj(G.5%), and Salmonella spp.(0.5%). Ah was never isolated. Multiple pathogens were commonly encountered, especially in those cases with either RV or ETEC infection. Forty-six(44.7%) of the 103 RV infections were associated with other potential pathogens. Of the 47 symptomatic cases infected with ETEC, 26(57.8%) were isolated with other pathogens.
Polymyxin B 의 장계세균항원(腸系細菌抗原)에 대한 항체산생(抗體産生) 증강작용(增强作用)에 관한 연구
이재구 대한미생물학회 1971 大韓微生物學會誌 Vol.6 No.1
Various kinds of antibiotics are generally believed to have inhibitory effects on the antibody response. However, as polymyxin B which beIongs to the cyclic poIypeptide group of antibiotic was found to have some enhancing effects on the antibody response of rabbits to enterobacterial common antigen (CA) under specified conditions, experiments were carried out on this problem with the following results. 1. When mixture of polymyxin B and CA derived from Salmonella typhimurium (STM) was treated 30 minutes at 37℃ and injected three times into rabbits by intravenous route, the antibody response to CA was weaker than rabbits injected CA only. 2. Mixture of polymyxin B and CA showed a marked antibody production when injected into rabbits primed with small amounts of heat-extracted antigen of STM, while the injection of CA alone showed low titers of response. 3. Mixture of polymyxin B and heat-extracted CA-containing antigen of Escherichia coli 014 also showed a increased antibody production than CA alone in rabbit primed with antigen of STM. 4. The effect of polymyxin B appeared in different ways. This antibiotic did not enhance the CA antibody responae in rabbits primed with small amounts of E. coli 0111 and 055, but enhance in rabbits primed with Shigella flexneri, 5. No enhancing effect on the antibody response was observed by polymyxin B in rabbits primed with CA. 6. No enhancing effect on the antibody response was also noted in rabbits primed with STM antigen in case poIymyxin B and CA were administered simultaneously but in veins of different places. 7. Bacitracin did not enhance the CA antibody response in primed rabbits with STM antigen, but neomycin slightly enhance the response. 8. Lipopolysaccharide showed no priming effect on the GA antibody response, and no enhancement of the CA antibody response in rabbits primed with STM 9.The priming effect of STM antigen against CA, antibody response was very weak as compared with the effect of CA derived from STM antigen.
부산지구(송도) 윤락여성(淪落女性)에 대한 현황 및 성병의 역학적(疫學的) 고찰
양학도,오양효 대한미생물학회 1968 大韓微生物學會誌 Vol.3 No.1
Prostitutes living in Sangdo beach in Puan, for two years period (from september 4, 1964 to August 28 1966) were invetigated for the present status and Venereal Diseases. The following results were obtained. 1. Age distribution.' The youngest was 18 years old and the oldest 29. The group between 22-25 vears okf was 72. 8,, approximately three fourth of aI1 prostitute.. 2. Educational background: From illiterate to college graduated. The group of graduated primary school was 80.7% approximately four fifth of all prostitutes. 3. Distribution of birth places: From all cities and provinces in Korea except Chejudo Island province. Kyongsang Namdo province was highest (24%), Kyongsan Pukdo province 18%, Pusan city 12%, and Seoul city 11% 4. Monthly and weekly Vener al Diseases examination to prostituts: Total examined cases were 7757, consisting of 323 monthly, and 75 weekly. Total numbers of disqualified persons were 592 (7. 63% of total examined), consisting of 25 monthly, and 6 weekly. 5. Clinical and laboratory findings of the rejected prostitutes at the Venereal Bisease examination: Among total cases of rejected 592, gonococcal positive cases were 2.89% staining by grams method, cervical erosions 3. 53%, and numerous pus celIs but gonacoccal negative 1. 53% 6. Seasonal distribution of prostitutes: Songdo beach is one of the famous sea shore sightseeing resort in Pusan. Therefore, numbers of prostitutes were increasing in hot season, summer and decreasing in cold season, winter. 7. Number of disqualified prostitutes at the Venereal Disease examination by seasonal trend: In autumn 18.04%, winter 8. 68%, spring 5. 85%, and summr 4. 43% in order as described, the decreasing tendency was observed. 8. Seolgical tests for syphilis: VDRL slide method and Kolmer-Wassermann reaction were performed to the prostitutea STS were positive by VDRL slide method in 8. 33 -27. 42% of the prostitutes. The results of sero-positive of syphilis showed tendency toward gradually increase from 1964 to 1966. 9. Authors were observed only l case or soft chancer, but neither lymphogrenuloma venezeum nor granuloma inguinale were detected.