피부 적용 겔제제의 첨가제에 의한 수분 보유력 평가

이은미,박종희,경기열,전일순,조혜정,지웅길 충남대학교 약학대학 의약품개발연구소 2004 藥學論文集 Vol.19 No.-

The aim of this study was to improve the moisturizing and water retaining effects of a gel containing poloxamer 407, glycerin, sod hyaluronate, sorbo(sorbitol 70%). Topical preparations were formulated as a gel containing different concentration poloxamer 407, glycerin, sod. hyaluronate, sorbo(sorbito1 70%), lipid(ceramide. sphingosine ratio 1:l). We tested a various combination of different additives for the moisturizing effect The water holding capacity of the mixture was measured using a moisture analyzer. In vivo test was carried out on human skin using Skicon-200 and water retaining effect was increased by addition of lipid. Water evaporation test was performed by various concentration of additives and water evaporation characteristics of the preparations were determined using the moisture analyzer. Moisturizing and water retaining effects was increased by adequate combination of various additives with topical gel formulations.

염산 독세핀 외용제의 피부 전달 시스템을 위한 제제 설계 및 평가

이은미,김정수,경기열,이계원,지웅길 忠南大學校 生命科學硏究院 醫藥品開發硏究所 2006 藥學論文集 Vol.21 No.-

Doxepin hydrochloride(Dox) is a dibenzoxepin-derivative tricyclic antidepressant and used topically for the short-term relief of moderately severe pruritus associated with atopy dermatitis. Dox topical emulsion(or liposome) formulations were evaluated with respect to their rheological properities, permeation through excised skin of hairless mouse and in vitro/in vivo accumulation in the skin. The apparent viscosity was increased according to the concentration of glycerin and decreased with an increase in the concentration of phosphatidylcholine(PC). The permeation rate of formulation increased with a high concentration of PC and showed no relationship with the change of formulations. Amount of accumulated drug in the excised skin of hairless mouse was decreased with a high concentration of glycerin, but increased according to PC concentration.

청각장애인의 사회통합 영향요인에 관한 연구

신은경,이익섭,손주영 한국장애인고용촉진공단 고용개발원 2009 장애와 고용 Vol.19 No.2

청각장애인은 고용상태가 불안정하며, 삶의 속도가 빨라지는 정보화 시대에 사회통합에 필요한 실제적인 지원체계가 결핍된 채 살아가고 있다. 이러한 상황은 그들의 장애정체감을 왜곡시키고, 타인과의 관계형성에 어려움을 겪게 하며, 나아가 사회통합을 저해하고 있는 것이다. 이에 본 연구에서는 청각장애인의 사회통합에 영향을 미치는 결정요인을 고용유무, 문제실제지지, 장애정체감, 사회적 교제관계로 설정하고 각 영향요인과 사회통합의 관계 경로를 검증해 보았다. 본 연구는 전국에 거주하고 있는 청각장애인 134명을 대상으로 조사하였으며, 확인적 요인분석을 통하여 분석한 결과, 모형의 적합도는 좋은 적합도(close fit)를 보여주었다(TLI .912, CFI .942, RMSEA .049). 변수 간의 관계구조의 검증결과를 보면, 청각장애인의 문제실제지지는 장애정체감에 정적영향을 주며, 장애정체감은 사회적 교제관계에 정적영향을 주고 있었다. 또한 사회적 교제관계는 사회통합에 정적영향을 주었다. 고용유무는 사회통합에 직접효과를 가진다고 검증되었다. 본 연구를 통하여 청각장애인의 고용에 관한 정책적 지원과 그들의 문제를 구체적이고 실제적으로 지지해줄 수 있는 체계의 마련이 필요함을 알 수 있었다. 이러한 지원체계의 마련이 궁극적으로는 사회통합에 영향을 주며, 동시에 장애인의 긍정적 정체감 형성을 돕고, 친밀한 대인관계를 형성하게 되는 것에도 효과가 있음이 검증된 것이다. The condition of employment the deaf is unstable, and they are maintaining their life with lack of practical support system for social integration in this fast turning information-oriented society. These circumstance distorts their disability identity, distresses on having relationship with other people, moreover it is hindering social integration. At this point, the study verifies the effect factors of the deaf to integrate in society by setting up an employment status, a disability identity, a problemoriented instrumental support and a social association relationship. This research targeted 134 the deaf group from the whole country, and by analyzing confirmatory factor analysis, it revealed suitability of the model is close fit(TLI .912, CFI .942, RMSEA .049). A result for verification in relationship system among variable is that, problemoriented instrumental support has positive relationship with the deaf ’s disability identity and disability identity is also related with social association relationship in affirmative way. It verified that an employment status has direct effect on social integration. Through this research, we felt the necessity of providing the political support for the employment and the system which could sustain their problems concrete and practically. By providing these supports, it will bring a good effect on social integration ultimately, and simultaneously, it will help disabled to form an positive identity, and it verified that it will support them to make a intimate personal relations.

중년여성 기성복 하의의 착용실태 및 맞음새에 관한 연구 : 만 34세에서 59세까지 For women aged 34 to 59

김은경,최혜선,이경미 대한가정학회 2003 Family and Environment Research Vol.41 No.3

This study was conducted to analyze the actual wearing conditions and body fit preferences of the middle-aged women's ready-to-wear lower body clothing. The aim was also to analyze lower body recognition, lower body satisfaction, fit preferences and size satisfaction according to age and degree of girth size. A questionnaire was developed and administered to 300 middle-aged women aged 34 to 59. Statistical tests such as descriptive analysis, crosstabs, and χ^2-tests were coducted to anaylze thdata and ascertain the differences between the ages. Lower body satisfaction and recognition were compared by T-test. Also Anova was used to analyze lower body recognition, satisfaction, fit preferences, and size satisfaction according to age and degrees of girth size. The results indicated that women aged 50 to 59 were more dissatisfied with the ready-to-wear sizing system and because of their body shapes had changed, their need for a larger size range system had also increased. Moreover, the element that most affected their purchase of ready-to-wear lower body clothing was the design followed by the size. The women, especially of the ages 50 to 59, showed a tendency to be dissatisfied with their lower bodies and they recognized that lower bodies had thichened compared to women aged 34 to 39 and 40 to 49. Analysis of body satisfaction, recognition, and fit preference according to girth size showed that the group of larger girth size recognized that their lower bodies were thicker and were more dissatisfied and preferred looser fittings than the groups of smaller women.

Rifampicin에 의한 것으로 추정되는 위막성 대장염1예

김수현,이은우,정종혁,문승현,김동한,양혁승,오영상,김호동,김도현,박혁,박정환,박경옥,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Pseudomembranous colitis, caused by altering the normal colonic flora and allowing the multiplication of Clostridium difficile, is an deleterious adverse effect of antibiotics. But it is rarely reported by rifampicin. Rifampicin is one of the first line drug in the treatment of tuberculosis and many patients are exposed to its potential adverse effects. We experienced a patient that had abdominal discomfort and hematochezia due to pseudomembranous colitis after receiving antituberculous medication, and which was probably caused by rifampicin. A 82 years old man was admitted with abdominal discomfort and hematochezia for one week. On the past history he had been diagnosed as endobronchial tuberculosis about 4 months ago. Colonoscopy revealed multiple discrete whitish mucosal lesion on rectosigmoid colon, and histologic findings were consistent with pseudomembranous colitis. The antituberculous agents were discontinued and vancomycin was administered. The patient's symptoms were resolved within several days. There was no recurrence after reinstitution of the antituberculous agents excluding rifampicin. We report here on a case of pseudomembranous colitis probably due to rifampicin.

기관골 신생증 1예

오영상,이은우,정종혁,문승원,김수현,김동한,양혁승,박정환,박경옥,강성수,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Tracheobronchopathia osteoplastica is a rare disorder of unknown cause characterized by the projection of numerous bony or cartilaginous submucosal nodules into the tracheobronchial lumen with sparing of the posterior membranous portion of tracheobronchial tree. In the past, most of the cases were diagnosed as secondary finding at autopsy. Nowaday, the key component of the evaluation is flexible fiberoptic laryngoscopy and bronchoscopy, which typically demonstrates irregular spicules of subrnucosal bone and cartilage projecting into the tracheobronchial lumen and causing various degrees of airway obstruction. A 45 years old man was visited Sunchon St. Carollo hospital due to discomfort on throat. We saw several nodules just below vocal cord via laryngoscope. The computed tomography revealed multiple small calcified nqdules on trachea and both main bronchi. Pathologic finding of bronchoscopic biopsy showed abnormal proliferation of bony and cartilagious nodules in the tracheal submucosa. These fingdings were consistent with tracheobronchopathia osteoplastica. We report here on a case of tracheobronchopathia osteoplastica with review of literature.

울산광역시민의 불소배합세치제 사용률

김지영,이재화,박혜경,김은경,김진범 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.1

Fluoride-containing toothpaste is one of useful tools to apply fluoride for prevention of dental caries. The purpose of this study was to survey the user rate of fluoride-containing toothpaste at home for the oral health education of the use of fluoride-containing toothpaste. Questionnaires about the use of fluoride-containing toothpaste were distributed to the children of primary middle schools and adults in Buk-gu(Northern District) of Ulsan Metropolitan City, Korea. Collected questionnaires from 374 primary school children, 505 middle school children and 161 adults were analyzed. All collected date were analyzed using the SPSS program. The obtained results were as follows; 1. 36 brands of toothpaste were being used at home. 29 brands contained fluoride and 9 brands were the toothpaste for children. 2. Among total respondents, 97.4% used the fluoride-containing toothpaste. 3. The user rate of fluoride-containing toothpaste were 97.9% among elementary school children, 97.2% among middle school children and 96.9% among adults. There was no significant difference among groups. 4. Among respondents using fluoride-containing toothpaste, SMFP-containing toothpaste were used by 90.9% of subjects, NaF;9.9%, combination of SMFP and NaF;0.1%. 5. Only 33.0% of respondents correctly knew whether they really used the fluoride-containing toothpaste or not.

최적이론에 의한 구개음화 재분석

최경애,이경은 목원대학교 인문과학연구소 2000 인문과학 Vol.9 No.-

SPE(Chomsky and Halle, 1968) 이후 많은 생성음운론학자들이 다양한 언어에서 나타나는 여러 가지 구개음화 현상의 일반성을 포착하기 위하여 선형적인 분석(C. -W. Kim, 1968 : 이병건, 1976 : Kim-Ren명, 1974 : S. -G Kim, 1976) 뿐 아니라 비선형적인 분석(S. -C. Ahn. 1985 : Booij and Rubach. 1987 : Borowsky, : 최경애, 1986 : Choi, 1988)에 이르기까지 다양한 분석을 시도하여왔다. 본 논문에서는 영어에 나타나는 구개음화 현상에 대한 분절음운론적 분석, 그 중에서도 특히 비선형적 분석 방법을 살펴보고, 그것을 최적 이론에 의해 재분석하고자 한다. 그리고, 그것이 기존의 분석방법보다 더 보편적이고 간단하며 더욱 설명력이 있음을 보이고자 한다.

한·중·일 공동 관광마케팅 협력방안에 관한 연구

서용건,김경호,이성은 제주대학교 관광과경영경제연구소 2004 産經論集 Vol.20 No.-

전남산 젓갈류의 유리아미노산 조성

허남칠,김선민,박은령,박평심,김경수,이명렬 조선대학교 기초과학연구소 1998 自然科學硏究 Vol.21 No.1

This study was designed to investigate the free amino acid compositions of salt-fermented fish products in the markets of Chonnam area. The results were as follows : The free amino acid compositions of salt-fermented fish products had varying figures according to the species of raw materials, that is, lysine and leucine were relatively abundant in Myul-chi jeot (salt-fermented anchovy), arginine inSae-woo jeot (salt-fermented small shrimp), glutamic acid inJa-oi jeot (salt-fermented small shrimp). lysine, arginine, alanine and phenylalanine in To-h jeot (salt-fermented trout), etc. Essential amino acid contents were contained 31.02%∼83.46% of total amino acids in all sample, and lysine and leucine were most abundant among essential amino acids. Especially tryptophan was the richest in Cham-jo-gae jeot, phenylalanine in To-ha jeot, Kal-chi-nae-jang jeot and Song-eo jeot in other essential amino acids. because the degree of protein degradation wouldl be influenced on fermentation periods, salt-concentration, fermentation temperature, etc, we expected more systemic research by some varied conditions and the developed analytical techniques on the salt-fermented fish products should be followed.