하악 우측 측절치에 발생한 선양 치성 종양

박미선,박호원,서현우,이주현 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

선양 치성 종양(adenomatoid odontogenic tumor)은 악골에 드물게 발생하는 치성 기원의 종양이다. 이전에는 법랑모세 포종(ameloblastoma)의 한 종류로 여겨졌으나 양성이며 재발되는 경우는 극히 드물다. 상악 견치에 호발하며 대개는 무증 상이지만 크기가 천천히 커져 무통성 종창을 일으킬 수 있다. 방사선학적으로 함치성 낭종(dentigerous cyst) 및 단방성 법 랑모세포종(unicystic ameloblastoma)과 매우 유사하다. 일반적으로 보존적인 소파술(curettage) 및 적출술(enucleation) 을 통해 치료한다. 본 증례는 하악 우측 측절치 미맹출을 주소로 내원한 10세 여자 환아에서 방사선 사진 검사를 통해 치아의 매복 및 병소를 확인하고 적출술을 시행하였다. 치아에는 브라켓을 부착하여 교정적 정출을 유도하였다. 조직학적 검사를 통해 선양 치성 종 양으로 확진되었으며 양호한 치료 결과를 보였기에 보고하는 바이다. Adenomatoid odontogenic tumor(AOT) is an infrequent odontogenic tumor which arise in the jaw. It was considered as a variant of ameloblastoma. The adenomatoid odontogenic tumor is clearly benign and, in contrast to the ameloblastoma, present a very low recurrence. It most often appears in the canine region of the maxilla. The adenomatoid odontogenic tumor is frequently asymptomatic, however it may cause painless swelling. The radiological findings of adenomatoid odontogenic tumor frequently share characteristics of dentigerous cyst and unicystic ameloblastoma. Conservative surgical enucleation and curettage are the treatment of choice. In this case a 10-year-old child was presented with mandibular right lateral incisor in unerupted. Radiographically, the tooth was impacted and a radiolucency was seen in the area. The lesion was enuclated without extraction of the tooth. Bracket was attached on the tooth for orthodontic extrusion installed. Histopathologically adenomatoid odontogenic tumor was revealed.

오매(Fructus Mume)의 항산화물질의 분리 및 특성연구

황현주,안은미,백남인,조재선,김해영 경희대학교 생명자원과학연구원 1998 硏究論文集 Vol.19 No.-

천연물로부터 새로운 항산화제를 개발하기 위한 연구의 일환으로 한방에서 사용되는 한약재 중의 하나인 오매(烏梅)의 물 추출물과 메탄을 추출물 및 순차 분획물에 대해 팜유, 우지와 돈지를 기질로하여 유지저아시험, Rancumat method, 전자공여작용 등으로 항산화성을 확인한 결과, EtOAc 분획물에서 강한 항산화 활성을 나타내어 column chromatography, thin layer chromatography를 통하여 활성성분에 관한 연구를 시도하였다. 1. 오매 용매분획물 중 EtOAc 분획물(400 ppm)은 유지저장실험(60℃)에서, 팜유, 우지와 돈지에 모두 우수한 효과를 나타내었으며, 특히 우지에서 높은 활성을 나타내었고, BHA(200 ppm)와 α-tocopherol(200 ppm)보다 활성이 높았다. 2. 오매 EtOAc 분획물(400 ppm)은 Rancimat method에서는 팜유, 우지와 돈지에 비교적 우수한 효과를 나타내었으며, 우지에서 AI가 4.39로 상당히 높은 활성을 나타내었다. 3. 오매의 용매분획물 중 EtOAc 분획물이 DPPH라디칼에 대한 강한 소거활성을 나타내었으며, 그 활성은 EtOAc 분획물의 농도에 의존하여 증가하였고, SC_(50)은 21.2μg/ml이었다. 4. 오매 EtOAc 분획물에서 분리한 8개 획분 중 E4에서 SC_(50)이 16.7μg/ml으로 높은 DPPH 라디칼 소거활성을 나타내었으며, 원인 물질은 여러 가지 스펙트럼 측정 결과 수종 물질이 혼합물인 것으로 밝혀져, 보다 순수한 형태로의 분리 후 정확한 동정의 시도가 요구되었다. Fructus Mume is the roasted hits of Prunus mwme and has been used as tradibonal Chmese medicine. The anboxidatwe effect of the extract from Fructus Mume was measured using different methodsn such as, electron donating abdihes(EDA), Rancimat and oven tests. The methanol extract obtained from the Fructus Mume was solvent-fractionated with ethyl acetate, n-butanol and water, respectively. The ethyl acetate fraction showed the highest antioxidative activity among them. To identify the compounds with antioxidative activity, the isolates from thm layer chromatography were studied further. This study demonstrates that Fructus Mume might be useful for the prevention or treatment of disorders associated with oxidative damage.

Tetracycline 처리된 조직유도재생술용 차폐막의 약제유리양상 및 구조적 변화

이성미,정현주 전남대학교 치과대학 1996 전남치대논문집 Vol.8 No.1

Tetracycline is known to be effective in eliminating periodontopathogens and have collagenolytic activity. This study was performed to observe the desorption kinetics and structural changes of tetracycline-treated barrier membranes for guided tissue regeneration. Four kinds of barrier membranes were tested : Tefgen??(American Custom Medical, USA) and Gore-Tex?? (W.L. Gore & Associates Inc., USA) as nonresorbable membranes : Resolut?? (polyglycolide & polylactide copolymer, W.L. Gore & Associates Inc., USA) and Biomend?? (collagen, Collatec Co., USA) as resorbable membranes. The membranes were cut into discs(diameter : 4㎜) and were immersed in 5% tridodecylmethylammonium chloride(TIMAC) ethanol and air-dried. The membrane discs were absorbed with 100㎍/㎖ tetracycline solution(pH 8) for one minute and dried. For desorption kinetics, TC treated discs were immersed in phosphate buffered saline solution(PBS, pH 7.4). PBS was exchanged daily and TC concentration was measured by absorbance at 276nm on UV spectrophotometer. To measure remaining antibacterial activity, discs of 1 day to 4 weeks after desorption were placed on Mueller Hinton agar containing Bacillus cereus and incubated aerobically in 37˚ C for twelve hours and the inhibition diameters were measured. To observe the structural change of membranes after TIMAC treatment or immersion in PBS, the membrane discs were examined under SEM. The results were as follows : 1. Total amounts of TC absorbed into membrane discs (0.7536㎟)were 2000㎍, 1800㎍, 2625㎍ and 2499㎍ for Tegen??, Gore-Tex??, Biomend?? and Resolut??. 2. The concentration of TC released from barrier membrane discs was maintained over 4㎍/㎖ until the fifth day in nonresorbable membranes and Resolut??, but until the fourth day in Biomend??. Until the ninth day in nonresorbable membranes and until the seventh day in resorbable membranes, the TC concentration was maintained over 1㎍/㎖. 3. The four membrane discs in the first day showed similar size of inhibition zone. One to four weeks later, the inhibition zone was much smaller in resorbable membrane discs than nonresorbable membrane discs. 4. Any structural change due to treatment of TIMAC was not observed on the nonresorbable membranes. Resolut?? did not show any structural change except fibrillar loosening during immersion period, but Biomend?? showed destruction of membrane structure from the first week of immersion. This study indicates that tetracycline treated barrier membranes lead to the sustained release of tetracycline for over 7 days. This slow release pattern of tetracycline may contribute to the favorable clinical outcome of guided tissue regeneration.

유당의 첨가가 성장기 암컷 흰쥐에서 골함량과 골밀도에 미치는 영향

최미자,조현주 啓明大學校 生活科學硏究所 2002 科學論集 Vol.- No.-

The effects of dietary lactose supplementation on bone mineral density and bone mineral content in growing rats are uncharacterized. We studied growing female rats fed a diet either control of supplemented with lactose for 9 weeks. The animal was scanned to determine the BMD and BMC using dual energy X-ray absorptiometry (FIXImus, GE Lunar Corporation, Madison, WI). Food intake and FER were not affected by loctose supplementation. But the lactose group had significantly higher spine bone mineral density(0.1517±0.0034(g/㎠) vs 0.1626±0.0095(g/㎠)) and spine bone mineral density/weight than the control group. And femur bone mineral density/weight as well as femur bone mineral content/weight were higher in the lactose supplemented group. These data suggest that lactose supplementation may be a useful way in growing children in which there is a desire to increase bone mineral density.

아로마요법이 수부 미세수술환자의 수면만족도, 통증 및 불안에 미치는 효과

신미영(외 4명) 신라대학교 (부산여자대학교) 2015 論文集 Vol.60 No.-

NIHSS 활용을 통한 뇌졸중 환자 간호의 질향상 전략

박경현,송경애,공혜성,나화주,유수경,박소영,김상희,최혜림,배희준,한문구,양미화 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.2

문제: 뇌졸중 환자를 돌보는 간호현장에서는 급성기 뇌졸중 환자의 증상악화에 대한 조기사정과 적절한 대처가 매우 중요한 문제이다. 그러나 임상현장에서는 이를 객관화하고 수치화하여 모든 의료진이 의사소통할 수 있는 유용한 도구를 사용하고 있지는 못하는 실정이다. 이러한 문제를 해결하기위해 NIHSS(National Institute of Health Stroke Scale)를 신경과 진료의사를 중심으로활용하고 있지만 아직 간호현장에서는보편적으로사용하지 않고있다. 이에 뇌졸중환자간호에 NIHSS를 활용하여 뇌졸중 증상악화의 조기사정과 빠른 대처로 궁극적으로는 뇌졸중환자 간호의 질을보다 향상시키기 위하여 본활동이 시도되었다. 목적: 첫째, 간호사의 NIHSS 측정 신뢰도의 현수준을 점검하고 이를향상시키기 위한 프로그램을 개발·적용한다. 둘째, 간호사가급성기 뇌졸중환자에게 NIHSS 측정을 통하여 뇌졸중악화를 얼마나 예측할 수 있는지 분석하고 이를 향상시킬수있는 방법을 모색한다. 셋째, 궁극적으로 급성기 뇌졸중 환자의 증상악화의 조기 발견과치료를위한의료진의 올바른 대처지침을 마련하여 이를 적용한다. 의료기관: 경기도에 소재한 대학병원의 뇌졸중 집중치료실 질 향상 활동: 첫째, 간호사의 NIHSS 측정 신뢰도 향상을 위해 「NIHSS 간호사 교육 프로그램」을 마련하였다.

간호학과 학생들의 노인에 대한 지식 및 태도

양경미,오현이,김진선,백영주 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.1

Objectives: The purposes of this study were to investigate nursing students' knowledge and attitudes toward the elderly, to examine the correlation between knowledge and attitudes, and to identify predictors of nursing students' attitudes toward the elderly. Method: Study participants were 195 nursing students who enrolled in a university located in Gwangju. Data were collected using structured questionnaires. Results: The average FAQ Ⅰ score for nursing students in this study was 50.2%. The level of nursing students' knowledge was relatively low compared to knowledge of Western nursing students in previous studies. Moreover, the average scores of psychological dimension and family/sociological dimension were lower than those of physical/physiological dimension. Negative biases were prevalent when the biased scores were computed. Nursing students also reported a little preference for working with older patients after graduation. Although the average attitude score was in a neutral range, the number of items in a negative attitude score range were more than those in a positive attitude score range. Contrary to expectation, the correlation between knowledge and attitude was not statistically significant. Nursing students who have clinical experiences with the elderly reported higher scores on FAQ Ⅰ than their counterparts. A current relationship with elderly living in their household was a significant predictor of nursing students' attitudes toward the elderly. Conclusion: Results from this study suggest that nursing education should be directed to increase the nursing students' knowledge and positive attitudes toward the elderly. Exposure to well elderly as clients before they are hospitalized or institutionalized may be helpful to increase nursing students' positive attitudes toward the elderly.

규산질 비료의 참외 흰가루병 발생 억제 효과

류나현,최미영,류연주,조현종,이용세,이영득,정종배 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4

토양에 시용한 규산의 참외 흰가루병에 대한 직접적인 억제 효과와 살균제의 방제 효과를 증진시킬 수 있는 보조효과를 조사하였다. 규산질 비료의 처리는 철가루병 균에 의해 감염된 참외 잎에서 균사의 생장과 분생포자의 형성을 억제함으로써 흰가루병 발생을 일부 억제할 수 있는 것으로 조사되었다. 물론 규산질 비료 자체만의 흰가루병 발생 억제 효과는 매우 미약한 수준이었으나 살균제의 흰가루병 방제 효과를 크게 증진시켜줄 수 있는 것으로 나타났다. 따라서 현재 농가 현장에서 밝혀지고 있는 규산질 비료의 참외 병해 발생 억제 효과는 주로 이러한 살균제의 효과를 증진시킬 수 있는 규산의 보조적인 작용에 기인하는 것으로 판단된다. 따라서 토양에 대한 적절한 수준의 규산질 비료의 시용은 살균제의 방제 효과 증진을 통하여 과다한 약제의 사용과 그에 따른 부작용을 경감시킬 수 있을 것으로 보인다. 규산질 비료의 흰가루병 발생 억제 효과를 증진시키기 위해서는 앞으로 병의 발생을 최대로 억제할 수 있는 참외 잎 중의 적정 규소 함량에 대한 검토 등의 추가적인 연구가 필요할 것이다. Silicon is known to accumulate in plants and results in greater resistance to diseases and insect pests. In this study, we investigated the effect of silicate fertUizer applied in soil on the development of powdery mildew of oriental melon Oriental melon seedlings of four-leaf stage were transplanted and grown in a plastic film house. silicate fertilizer was applied to maintain soil available SiO₂ level of 200 ㎎/㎏ one week before transplanting. Fungicide trinumizol was sprayed three times; one, two, and three weeks after transplanting. Sphaerotheca fuliginea was inoculated 2 weeks after transplanting. The number of infected leaf and the number of fungal colony in leaves were measured one, two, and three weeks after the inoculation. Three weeks after the fungal inoculation, in the treatment of fungicide triflwnhl, infected leaf numbem and number of colony per leaf were reduced by 10 and 58% respectively. In the silicate fertilizer treatment, infected leaf numbers and numbers of colony per infected leaf were suppressed only by 6 and 16%, respectively, and the efficacy was lower than that of the fungicide triflumizol. The combined treatment of silicate fertilizer and the fungicide suppressed powdery mildew more effectively, and infected leaf numbem and numbem of colony per leaf were reduced by 31 and 80%, respectively. These results indicate that although silicate fertilizer itself is not much effective in the suppression of powdery mildew, it can significantly enhance the efficacy of the fungicide.

고정근무간호사와 교대근무간호사의 건강상태와 직무만족도에 관한 연구

성미혜,김현주,한영미 대한간호학회 간호행정학회 2007 간호행정학회지 Vol.13 No.1

Purpose: This study is conducted to compare and analyse the health status and job satisfaction of nurses. Method: The subjects were a group of 90 nurses on fixed day nurse and the other group of 100nurses on night nurse. The collected data were analysed by using the SPSS WIN(10.0) program for descriptive statistics, t-test x²-test, ANOVA, and Pearson correlation coefficient. Result: There was a significant difference according to years in services. In nurses on day shift, there was a inverse correlation between the health status and job satisfaction. And in nurses on day shift, job satisfaction levels differed significantly depending on personality, satisfaction to pay, and current health status. In nurses on night shift, nurses' job satisfaction levels differed significantly depending satisfaction to pay. Conclusion: It was confirmed that health of nurses is greatly affected by shift work. so, it is very important to maintain and promote their health status in nurses on night shift. We must find out the factors that greatly affect health of nurses, and continuously make an effort to improve the working environment.

매복 반곡된 상악 중절치의 외과적 처치에 관한 증례보고

백병주,윤현두,김미경 大韓小兒齒科學會 1991 大韓小兒齒科學會誌 Vol.18 No.2

The treatment of unerupted tooth are surgical exposure,orthodontic repositioning ,transplantation and extraction. In treating unerupted tooth,it must be considered to position and dilaceration of unerupted tooth,patient age,requirement of patient. Case mentioned here is autotransplantation of unerupted tooth and dilacerated central incisor. For the successful treatment,it is required space of trancsplanted tooth and good oral hygiene before surgery.We escape trauma of periodontal ligament and cementum during surgery.We observe occlusion,inflammation,development of roots after transplantation.