한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

외과 영역에 있어서 Venoplant^(R)의 임상적 고찰

김재호,노승무,장일성,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

The clinical effects of Venoplant^(R) was observed in 30 cases with conditions that a surgical management has been taken. Venoplant^(R) was administered via intravenous root with 2 to 5 ml, 2 to 4 times per one day for postoperatively 3 to 7 days. An overall effectiveness rate was 66.6% and mild nausea was observed in one case. In conclusion, Venoplant^(R) was effective in the edema, pain, and redness on the wound.

골수염의 진단에 있어서의 Tc-99m Hexamethylpropylene amine oxime 백혈구 스캔의 임상적 유용성

최상호,김양수,정준원,정진원,추은주,서동대,배인규,양승오,우준희,류지소 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

배경 : 골수염의 진단에 있어 Technetium-99m을 이용한 삼상 골스캔(Tc-99m MDP스캔)은 단순방사선 검사상 정상소견을 보이는 경우에 쓰이는 1차적 검사로 매우 높은 민감도를 보인다. 그러나 Tc-99m MDP 스캔은 골절이나, 정형외과적 삽입물, 신경병적 관절병변과 같이 뼈의 재형성이 증가되는 상황에서도 양성소견을 보여 특이도가 낮은 단점이 있다. 이러한 단점을 보완하고자 골수염의 진단에 있어 Tc-99m HMPAO 백혈구 스캔의 유용성을 알아보고자 하였다. 대상 및 방법 : 골수염이 의심되어 Tc-99m HMPAO 백혈구 스캔을 시행했던 15명의 의무기록을 후향적으로 분석하였다. 골수염의 확진은 임상관찰 소견과 배양검사 결과와 병리소견을 기준으로 하였다. 결과 : 골수염의 진단에 있어 Tc-99m HMPAO 백혈구 스캔의 민감도와 특이도는 각각 100%와 78%였고 Tc-99m HMPAO 스캔의 경우는 100%와 18%였다. 가장 흔한 원인균은 methicillin-resistant S. aureus였다. Tc-99m MDP 스캔에서 양성소견을 보였던 환자중 3명의 환자가 Tc-99m HMPAO 백혈구 스캔에서 음성 소견을 보였으며 이 환자들은 추적관찰상 골수염이 없는 것으로 확인되었다. 결론 : Tc-99m HMPAO 백혈구 스캔은 골수염의 존재를 진단하는데 있어 민감도와 특이도가 높으며, 특히 뼈의 재형성이 증가되어 Tc-99m MDP 스캔의 특이도가 낮게 나타나는 상황에서 유용하리라 사료된다. Background Three phase bone scintigraphy, performed with technetium-labeled diphosphonates (Tc-99m MDP scan), is the very sensitive radionuclide procedure of choice for diagnosing osteomyelitis. But, Tc-99m MDP scan is less specific when bone remodeling is increased. To overcome this limitation, we evaluated the diagnostic value of technetium-99m hexamethylpropyleneamine oxime (HMPAO) labeled leukocyte scan in osteomyelitis. Methods : We retrospectively reviewed 15 patients with suspected osteomyelitis who performed Tc-99m HMPAO labeled leukocyte scan. The diagnosis of osteomyelitis was based on clinical course and bacterial culture, and pathologic findings. Results The sensitivity and specificity of Tc-99m HMPAO leukocyte scan was 100% and 78%, and those of Tc-99m MDP scan was 100% and 18%, respectively. The most common organism was Methicilein-Resistant S. aureus. Among the patients that showed persistent accumulation on Tc-99m MDP scan, three patients showed no uptake on Tc-99m HMPAO leukocyte scan and these patients were confirmed that had no osteomyelitis. Conclusion : Tc-99m HMPAO leukocyte scan is a useful test for determining the presence or absence of osteomyelitis, especially under condition that bone remodelin is increased.

A Study on the Korea Database Industry Promotion Act Legislation

Bae, Seoung-Hun,Lim, Jung-Sun,Lee, Jae-Jin,Park, Cheon-Woong,Shin, Kwang-Min,Kang, Sang-Kyu,Yoon, Jin-Sun,Shin, Minsoo Korea Institute of Science and Technology Informat 2013 Journal of Information Science Theory and Practice Vol.1 No.3

The Database Industry Promotion Act was proposed at the National Assembly plenary session on July 26, 2012 and since then it has been in the process of enactment in consultation with all the governmental departments concerned. The recent trend of economic globalization and smart device innovation suggests a new opportunity and challenges for all industries. The database industry is also facing a new phase in an era of smart innovation. Korea is in a moment of opportunity to take an innovative approach to promoting the database industry. Korea should set up a national policy to promote the database industry for citizens, government, and research institutions, as well as enterprises. Above all, the Database Industry Promotion Act could play a great role in promoting the social infrastructure to enhance the capacity of small and medium-sized enterprises. This article discusses the background of the development of the Database Industry Promotion Act and its legislative processes in order to clarify its legal characteristics, including the meaning of the act. In addition, this article explains individual items related to the overall structure of the Database Industry Promotion Act. Finally, this article reviews the economic effects of the database industry for now and the future.

Prevalence, Correlates, and Comorbidity of 12-Month Tobacco Dependence among Ever-smokers in South Korea, During 1984-2001

Jeon, Hong Jin,Hahm, Bong-Jin,Lee, Hae-Woo,Hong, Jin Pyo,Bae, Jae-Nam,Park, Jong-Ik,Kim, Jang-Kyu,Bae, Ahn,Park, Jong Han,Chung, Eun-Kee,Shin, Jong-Ho,Choi, Yong-Seoung,Chung, In-Won,Lee, Hyo Jung,Cho The Korean Academy of Medical Sciences 2008 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.23 No.2

<P>The rate of dependence among ever-users of a drug indicates the risk of developing dependence once an individual has been exposed to the drug. This is the first study to investigate 12-month tobacco dependence (TD) among ever-smokers in a community-based population. Analyses were based on two national studies of representative samples aged 18-64 in 1984 (n=5,025) and in 2001 (n=6,275), conducted with household visits and face-to-face interviews. The rates of 12-month TD among ever-smokers in men showed no significant difference between 51.6% in 1984 and 50.6% in 2001. On the contrary, the rates in women significantly increased from 33.3% in 1984 to 52.8% in 2001. After adjusting for the sociodemographic variables, 'male gender' was significantly associated with 12-month TD among ever-smokers in 1984, but not in 2001. 'Unmarried' was significantly associated in 2001 but not in 1984. 'Alcohol dependence' was the only psychiatric disorder associated with 12-month TD in both study years. In conclusion, 12-month TD was found in about 50% of ever-smokers, and gender differences between the rates of 12-month TD which was observed in 1984 disappeared in 2001. Individuals with 12-month TD showed higher comorbidity with alcohol dependence than ever-smokers without TD.</P>

Feasibility and safety of laparoscopic resection following stent insertion for obstructing left-sided colon cancer

Seoung Yoon Rho,Sung Uk Bae,Se Jin Baek,Hyuk Hur,Byung Soh Min,Seung Hyuk Baik,Kang Young Lee,Nam Kyu Kim 대한외과학회 2013 Annals of Surgical Treatment and Research(ASRT) Vol.85 No.6

Purpose: The aim of this study was to assess the feasibility and safety of laparoscopic resection following the insertion of self-expanding metallic stents (SEMS) for the treatment of obstructing left-sided colon cancer. Methods: Between October 2006 and December 2012, laparoscopic resection following SEMS insertion was performed in 54 patients with obstructing left-sided colon cancer. Results: All 54 procedures were technically successful without the need for conversion to open surgery. The median interval from SEMS insertion to laparoscopic surgery was 9 days (range, 3-41 days). The median surgery time was 200 minutes (range, 57-444 minutes), and estimated blood loss was 50 mL (range, 10-3,500 mL). The median time to soft diet was 4 days (range, 2-8 days) and possible length of stay (hypothetical length of stay according to the discharge criteria) was 7 days (range, 4-22 days). The median total number of lymph nodes harvested was 23 (range, 8-71) and loop ileostomy was performed in 2 patients (4%). Six patients (11%) developed postoperative complications: 2 patients with anastomotic leakages, 1 with bladder leakage, and 3 with ileus. There was no mortality within 30 days. Conclusion: The present study shows that the presence of a SEMS does not compromise the laparoscopic approach. Laparoscopic resection following stent insertion for obstructing left-sided colon cancer could be performed with a favorable safety profile and short-term outcome. Large-scale comparative studies with longterm follow-up are needed to demonstrate a significant benefit of this approach.

The Arabidopsis AtLEC Gene Encoding a Lectin-like Protein Is Up-Regulated by Multiple Stimuli Including Developmental Signal, Wounding, Jasmonate,Ethylene, and Chitin Elicitor

Seoung Hyun Lyou,Hyon Jin Park,Choonkyun Jung,Hwang Bae Sohn,이가람,김정호,김민균,최양도,정종주 한국분자세포생물학회 2009 Molecules and cells Vol.27 No.1

The Arabidopsis gene AtLEC (At3g15356) gene encodes a putative 30-kDa protein with a legume lectin-like domain. Likely to classic legume lectin family of genes, AtLEC is expressed in rosette leaves, primary inflorescences, and roots, as observed in Northern blot analysis. The accumulation of AtLEC transcript is induced very rapidly, within 30 min, by chitin, a fungal wall-derived oligosaccharide elictor of the plant defense response. Transgenic Arabidopsis carrying an AtLEC promoter-driven -glucuronidase (GUS) construct exhibited GUS activity in the leaf veins, secondary inflorescences, carpel heads, and silique receptacles, in which no expression could be seen in Northern blot analysis. This observation suggests that AtLEC expression is induced transiently and locally during developmental processes in the absence of an external signal such as chitin. In addition, mechanically wounded sites showed strong GUS activity, indicating that the AtLEC promoter responds to jasmonate. Indeed, methyl jasmonate and ethylene exposure induced AtLEC expression within 3-6 h. Thus, the gene appears to play a role in the jasmonate-/ethylene-responsive, in addition to the chitin-elicited, defense responses. However, chitin-induced AtLEC expression was also observed in jasmonate-insensitive (coi1) and ethylene-insensitive (etr1-1) Arabidopsis mutants. Thus, it appears that chitin promotes AtLEC expression via a jasmonate- and/or ethylene-independent pathway.

웹 정보를 활용한 한국과 미국의 장단기 나노기술 경쟁력 비교 분석

배성훈(Seoung Hun Bae),신광민(Kwang Min Shin),윤진선(Jin Seon Yoon),강상규(Sang Kyu Kang),김준현(Jun Hyun Kim),조수지(Su Ji Cho),이기광(Ki-Kwang Lee) 한국지역정보화학회 2016 한국지역정보화학회지 Vol.19 No.1

본 연구는 빅 데이터 중 하나인 웹페이지 규모를 나노기술 경쟁력의 지표로 활용함으로써 한국과 미국의 장 · 단기적 국가 나노기술 경쟁력을 비교 · 분석하고자 하였다. 이를 위하여 ‘나노기술’, ‘나노전자’ 및 ‘나노소재’라는 대표 검색어를 선정하고 지수평활법과 Bass 모형을 사용하여 향후 10년간 장 · 단기 웹페이지 규모 변화를 예측하였다. 분석 결과 ‘나노기술’ 검색어에 대한 관련 웹페이지는 우리나라에서 2028년경에 이르러 본격화할 것으로 나타났다. 또한 우리나라는 ‘나노전자’, ‘나노기술’, ‘나노소재’ 순으로 미국과의 기술 격차를 가지고 있는 것으로 분석되었으나, 이러한 기술격차는 시간의 흐름에 따라 상당 수준 좁혀질 것으로 예상되었다. 본 연구는 웹페이지 규모 자료를 이용함으로써 분석 과정에 소요되는 시간과 비용을 절감하였으며, 이를 통해 국가 간 또는 지역 간 기술경쟁력 분석에 새로운 조사 가능성을 제시하였다는 데에 그 의의가 있다. This research aims to compare the national nanotechnology competitiveness between Korea and the United States in short and long term using the web page volume which was utilized as the indicator of the nanotechnology competitiveness. The terminologies, i.e., ‘nanotechnology’, ‘nanoelectronics’ and ‘nanomaterials’ were selected as the keyword of search in web page to conduct this research problem. The exponential smoothing method and the Bass model were used to forecast the change of the web page volume during next decade. As the results, it was found that the web page related to ‘nanotechnology’ keyword will be upswept in the year 2028 in Korea. The biggest technological gap between the two country was founded in ‘nanomaterials’, followed by ‘nanotechnology’ and ‘nanoelectronics’, but these gaps were expected to become narrow as the passage of time. The result of this research would be significant that potential values of web page volume were suggested for the national or regional comparative analysis with the effectiveness of time and costs for survey.

열산화 탄탈륨 산화막의 전기적 특성 평가

김승균(Seoung-Gyun Kim),유은성(Yu-Eun Seong),백경진(Baek-Kyung Jin),이종모(Jong-Mo Lee),배병성(Byung Seong Bae) 대한전자공학회 2022 대한전자공학회 학술대회 Vol.2022 No.6

나노기술 경쟁력 지수의 개발

배성훈(Seoung-Hun Bae),김준현(Jun Hyun Kim),신광민(Kwang Min Shin),윤진선(Jin Seon Yoon),신민수(Min Soo Shin),강상규(Sang Kyu Kang) 한국생산제조학회 2016 한국생산제조학회지 Vol.25 No.5

In this study, we have developed an index suitable for determining nanotechnology competitiveness. The analytic hierarchy process is used to compared Korean nanotechnology competitiveness with nine high-ranked countries in terms of OECD GDP along with China, India, and Russia. We fund Korea to be ranked fourth among the twelve countries. Despite Korean high rank, it has some problems with regard to infrastructure and industry development. To become a leading country in nanotechnology, Korea needs to strategically invest into research capabilities for nanotechnology, support industry convergence based on nanotechnology, and increase investment into infrastructure development. The findings of this study will contribute to enhancing nanotechnology-related policies and research.