제 2 회 대한소화기학회 단기과정 : 소화기계의 핵의학 영상

양승오,양승오 대한소화기학회 1995 단기과정 Vol.1995 No.-

99mTc-MDP 골스캔을 이용한 폐암의 골전이성에 대한 후향적 분석

양승오,고은미,이명혜,이명철,조보연,고창순 대한핵의학회 1988 핵의학 분자영상 Vol.22 No.1

최근 3년간 대한방사선의학회지에 실린 논문의 주제별 분석 및 참고문헌의 인용지수 등에 대한 연구

양승오 대한영상의학회 1990 대한영상의학회지 Vol.26 No.4

The papers in the Journal of the Korean Radiologic Society(JKRS) during recent three years were surveyed by analysis of their types, topics, organs, employed modalities, and cited literatures. Citation analysis is a method of studying interrelationships between papers and journals, and the most important application of citation analysis is in studies of science policy and research evaluation to evaluate the implementation of science policy and to monitor research performance. Using these citation analysis to map the journal communications network may indicate to more efficient scientific progress. Total number of papers published by JKRS for recent 3 years was 473 papers(Clinical : 354, Case report : 91, Experimental : 26, Educational : 2f). The most common organ system of the papers was abdomen(head and neck, chest, musculoskeletal, cardiovascular, and urologic system in the order of decreasing frequency). The most popular topic was techniques including newer modalities and i terventional radiology and normal measurement, tuberculosis, hepatoma, normal anatomy and the like followed. Total number of cited references was 8,642(18.26 per one paper), and the average number of authors per paper was 4.83. The most frequently used modality was CT(41%) followed by simple radiography, ultrasonogram, fluoroscopic study, angiography, nuclear imaging, and MRI. Using this kind of analysis as a guide for writing a paper for the JKRS, it could be well-organized and uplifted in its format and contents.

메네트리에병의 1 예보고 -위거대점막주름의 방사선학적 감별-

양승오 대한영상의학회 1986 대한영상의학회지 Vol.22 No.4

Diffuse tremendous thickening of gastric wall caused by excessive proliferation of the mucosa of unknown cause was first decribed by Nenetrier in 1888. The disease is highly uncommon, but the exact preoperative diagnosis a crucial because of the more excellent prognosis than other malignant lesions including gastric lymphoma and in filtrative gastric carcinoma. The authors recently experienced a case of Menetrier's disease which had been diagnosed as gastric lymphoma preoperatively. Radiologic differentiation is not impossible between this extremely rare disease and other mimicking malignant lesions, that is the reason why we introduce radiographic findings of the case by comparison with gastric with gastric lymphoma of giant rugal type and infiltrative gastric carcinoma. Typical upper G-I series findings of the case are ; 1) Enlarged tortuous proximal gastric rugal folds only along the greater curvature, 2) Perpendicular lines of barium spicules trapped by apposed folds with clubbed or forked appearance, 3) Abrupt transition of the lesion to normal stomach, 4) No luminal narrowing and retained but sluggish peristalsis. Thus radiolgists can diagnose Menetrier's disease scrupulously based on critical application of enlarged folds pattern and extent of the lesion in association with other radioligic features and clinical history of fairly long duration. Brief review of clinical and pathologic features about Menetrier's disease is included.

기질화 폐염의 전산화단층촬영소견 -증례 보고 -

양승오 대한영상의학회 1988 대한영상의학회지 Vol.24 No.2

기질화 폐염이 원위 폐야에서 고립성으로 오래 지속되는 경우에 단순 흉부사진만으 로는 악성 종양과의 감별이 어렵다. 최근에 고해 상력의 전산화 단층 촬영으로 폐실질의 병 변의 진단에 많은 도움을 얻고 있으나 원위부의 기질화 폐염의 전산화 단층촬영소견은 흔하 지 않은편이다 저자들은 수술을 하여 병리학적으로 확인된 기질화 폐염 1예의 전산화 단층 촬영소견을 보고하는 바이다. Diagnostic dilemma of persistent mass-forming parenchymal opacity in the lung periphery occurs occasionally in the realm of diagnostic radiology. Until recently, literature on the role of computed tomography in peripheral organizing pneumonia, which is difficult to differentiate from malignancy, has little been published. We experienced one case of pathologically proven organizing pneumonia diagnosed preoperatively by chest Ct. When it comes to solitary peripheral mass density in the lung, we think that CT can be proved useful in the diagnosis of benign organizing pneumonia by showing regular and smoothly corrugate margin, peripheral contrast enhancement with inner low density, and air-trapping by intervening normal lung parenchyma.

원인불명성 조직구 증식증의 골 스캔 소견과 방사선학적 소견의 비교

양승오 대한영상의학회 1988 대한영상의학회지 Vol.24 No.5

골 스캔과 방사선학적 검사를 함께 얻을수 있었던 30예의 원인 불명성 조직구 증식 증 환자에서 종례에 보고된 바 있는 골 스캔의 비교적 낮은 진단적 정확도 (50% 내외)의 진위와 이질환에성의 골병변의 양상과 분포를 알기위해 후향적 분석을 시도하였다. 대상으 로 한 30예의 연령분포는 14개월에서 45세였고 평균 9.3세 20대 이상의 4예를 제외하면 26 예가 14세 이하였다. 단일 골병변이 15예 다발성 골병변이 12예 정상이 3예이었고 41개 해 부학적 영역과 90개 이상의 산술적 병소를 관찰하였으며 이들의 분포양상은 두개골 (11/41) 대퇴골(7/41) 척추골(6/4) 늑골, 하악골 등의 순서를 나타내었다. 방사선학적 소견과 비교한 골 스캔의 예민도는 85%로서 과거의 보고와는 상당한 차이가 있었고 골 스캔으로 경과 추 적을 시행한 7예에서는 2내지 20 개월에 치료에 따른 골 병소의 정상화를 볼수 있었다. 골 스캔은 감마 카메라의 해상력과 방사성 표지 화합물의 효율이 향상되고 관심부위에 대한 확 대 영상등을 이용함에 따라서 원인 불명성 조직구 증식증의 진단과 경과추적에 제한된 부위 의 방사선학적 검사와 더불어 유용한 검사라고 할 수 있다. A retrospective analysis of concurrent bone scintigraphs and radiographs of 30 patients with histologically confirmed histiocytosis X was carried out to assess the pattern and distribution of bone lesion and the sensitivity of bone scintigraphy with reference to skeletal radiography. Totals of 41 regional and over 90 numeric bone lesions were found in all patients. Single bone lesions were seen in 15 patients and multiple lesions in 12 patients. Three patients had not revealed bone lesion. Distribution of lesions was skull, vertebrae. femur, ribs, mandible and the like, in the order of decreasing frequency. Unlike previous citations, the sensitivity of bone scan was relatively as high as over 85% and it showed two lesions of skull and clavicle which escaped from radiologic detection. Improvement of mechanical resolution and bone-seeking radiopharmaceuticals made it possible to detect bone lesions in histiocytosis X more accurately than previous decade. Bone scintigraphy could be the effective, heopful diagnostic procedure in the initial diagnosis as well as convenient follow-up method in histiocytosis X.

($TGF-{\beta}$)이 Minocycline을 전처리한 사람 치주인대세포의 활성에 미치는 영향

양승오,유형근,신형식,Yang, Seung-Oh,You, Hyung-Keun,Shin, Hyung-Shik 대한치주과학회 1996 Journal of Periodontal & Implant Science Vol.26 No.2

The initial events required for periodontal regeneration is the attachment, spreading, and proliferation of appropriated cells at the healing sites. These have been reported that minocycline stimulates the attachment of periodontal ligament cells, and also $TGF-{\beta}1$ enhances the proliferation of periodontal ligament cells. The purpose of the present study was to evaluate the effects of $TGF-{\beta}1$ on the cellular activity of minocycline treated human periodontal ligament cells. Periodontal ligament cells were obtained from the explants of healthy periodontal ligaments of extracted 3rd molars or premolar teeth extracted from the patients for orthodontic treatment. The cells were cultured in minimal essential medium(${\alpha}-MEM$) supplemented with 10.000units/ml penicillin, $10,000{\mu}g/ml$ streptomycin and 10% FBS(fetal bovine serum) at $37^{\circ}C$ in a humidified atmosphere of 5% carbon dioxide and the 5th to the 8th passages of the cells were used. To evaluate the effect of minocycline on cell attachment, the cells were seeded at a cell density of $1.5{\times}10^4$ cells/well in 24-well culture plates and treated with $20{\mu}g/ml$ and $100{\mu}g/ml$ of minocycline for 1.5 h. After trypsinization, the cells were counted with hemocytometer and were taken photographs for observation of cellular morphology. To evaluate the effect of $TGF-{\beta}1$ on minocycline-pretreated periodontal ligament cells, the cells were seeded at a cell density of $1{\times}10^4$ cells/ well in 24-well culture plates and treated with $20{\mu}g/ml$ and $100{\mu}g/ml$ of minocycline for 1.5 h. After incubation, 1 and 10ng/ml of $rh-TGF-{\beta}1$ were also added to the each well and incubated for 1 and 2 days, respectively. Then, MTT assay, DNA synthesis($^3H-thymidine\;assay$), and protein and collagen assay(3H-proline assay) were carried out. In the MIT assay, after 200ul MTT solutionlconeentration of 5mg/ml) were added to the each well of the 24-well plates and incubated for 3 hours, and 200 ul DMSO were added so as to dissolve insoluble blue formazan crystals which was formed in incubated period. Then it read plates on a ELISA reader. For mitogenic assay, 1 uCi/ml $^3H-thymidine$ was added to each well for the final 2 hours of the incubation periods. After labeling, the wells were washed 3 times with ice cold PBS and 4 times with 5% TCA to remove unincorporated label and precipitate the cellular DNA. DNA, with the incorporated $^3H-thymidine$, was solubilized with 500 ul of 0.1% NaOH/0.1% SDS. A 250 ul aliquot was removed from each well and placed in a scintillation vial with 4ml of scintillation cocktail. Using an liguid scintillation counter, counts per minute(CPM) were determined for each samples. 3 uCi/ml $^3H-proline$ was added to each well for the final 4 hours of the incubation periods and total protein and percent collagen synthesis were carried out. The results indicate that minocycline treated group with $100{\mu}g/ml$ concentration for 1.5 hours significantly increased than that of control in cell attachment, and cell process is also evident compared with that of control in cell morphology, and the cellular activity and DNA synthesis rate of cells treated minocycline and $TGF-{\beta}1$ significantly increased than that of control values, but were below to values of the $TGF-{\beta}1$ only treated group in MIT assay and $^3H-thymidine\;assay$, and the total protein synthesis of minocycline and $TGF-{\beta}1$ treated group also significantly increased than that of control values, but the percent collagen synthesis of tested group significantly decreased to compared with control. On the above the findings, the tested group of minocycline and $TGF-{\beta}1$ did not increase the eff

변압기 보호시스템

양승오,Yang, Seung-O 한국열병합발전협회 2002 열병합발전 Vol.28 No.-

CPITN을 이용한 임신여성의 치주상태에 대한 연구

양승오,신형식 원광대학교 치의학연구소 1992 圓光齒醫學 Vol.2 No.2

Many studies of gingivitis in pregnancy have been reported over the years and many different determinations to it's cause and frequency have been resulted. 240 Korean pregnant women were selected, who were in pregnancy from 2 to 10 months visited Wonkwang university hospital and other maternity clinic at Iri city in 1992. The periodontal conditions were assessed according to the community periodontal index of treatment needs(CPITN). The aim of this survey was to obtian information which is necessary for the planning of preventive programs of periodontal disease for pregnant women. The percentage of pregnant women having pocket depth, plaque index, gingival index and periodontal index was higher with the month of pregnancy, reached a maximum of third trimester 03rd trimester, posterior teeth, periodontal index -1.19 0.70). The difference of each age group in pregnant women was statistically not significant and comparing PD, PI, GI, PEI of facial and lingual surface, in lingual surface were higher surface. The result of CPITN that pregnant women had a healthy periodontal condition(34.17%), improving the personal oral hygiene(48.33%), need for professional cleansing of the teeth(10%), need for complex treatment(7.5%). The study has shown that gingival changes are more effective in local irritant than plasma level of sex-hormone and need oral hygiene instruction than professional treatment.

위평활근육종과 평활근육의 방사선학적 고찰

양승오 대한영상의학회 1985 대한영상의학회지 Vol.21 No.1

Smooth muscle tumors of stomach are unusual tumors, accounting for 1-3% of primary gastric malignancies. Diagnosis of these tumors is important because of the more favorable prognosis of this tumor than that of gastric carcinoma. A retrospective study was made in 18 patients who had pathology-proven gastric leiomyoma and leiomyosarcoma to identify radiologic characteristics for recent 6 years from Jan. 1978 to July. 1984 at department of radiology, Seoul National University Hospital. The results were as follows: 1. Age of 13 cases of gastric leiomyosarcoma ranged from 36 to 70 with average of 51 and the male to female raio was 10:3. Age of 5 cases of gastric leiomyoma ranged from 24 to 67 with average of 44 and the male to female raio was 3:2. 2. Clinically, gastric leiomyosarcoma had epigastric pain in 7 cases, palpable mass in 4 cases, melena in 3 cases, hematemesis in 2 cases, 5 cases of gastric leiomyoma also had above symptoms respectively. 3. Of the 13 cases of gastric l iomyosarcoma studied by upper gastrointestinal examination, 6 cases(32%) involved the fundus, 10 cases(50%) in the body, 4.. The size of the 13 gastric leiomyosarcomas ranged from 5 to more than 20cm in diameter. The size of the 5 gastric leiomyomas ranged from 3 to 9cm in diameter. 5. The growth type of gastric leiomyosarcoma was exophytic in 8 cases, endogastric in 1 case and mixed pattern in 4 cases. The growth type of gastric leiomyoma were exophytic in 1 case, endogastric in 2 cases and mixed in 2 cases. 6. Mucosal pattern of gastric leiomyosarcoma were mainly effaced pattren in 10 cases(77%), but 3 cases(23%) showed irregular destruction. 1 case of gastric leiomyoma showed mucosal irregularity. 7. Ulceration was present in 10 cases of gastric leiomyosarcoma either single or multiple. 2 cases of gastric leiomyoma showed small ulcerations. Calcifiation was seen in one case of cellular leiomyoma. 8. Diagnostic accuracy of gastric leiomyosarcoma and gastric leiomyoma by U.G.I. stud was 90% and 80% respectively. One case of gastric leiomyosarcoma arose from the fundus of stomach was diffcult to difficultiate from advanced atomach cancer, Borrmann type 1.