작업관련성 수근관증후근 감시체계

정우철,권호장,하미나,노상철,권범선,현정근,이성재,이종민,권정이,김준성,백남종,이호,이경우,이삼규 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

목적: 작업관련 근골격계질환은 중요한 직업관련성 질환 중의 하나이고 작업관련 수근관증후군은 이러한 작업관련 근골격계질환 중에서도 많은 부분을 차지한다. 이 연구는 작업관련 수근관증후군의 역학적 특성에 대해 알아보고자 수행되었다. 방법: 본 연구에서는 '수근관증후군 감시체계'를 통해 2000년 6월부터 2003년 2월까지 보고 된 672례의 수근관증후군 사례를 분석하였다. 직업력이 확인된 314명을 대상으로는 직업 및 작업내용에 따라 작업관련성 수근관증후군의 비율이 어떻게 달라지는지를 분석함으로써 수근관증후군 위험요인을 조사하였다. 결과: 직업력이 확인된 314명의 환자 중 작업 관련성이 의심되는 사람은 228명 (72.6%) 이었다. 직업별로는 '단순노무종사자', '농림어업숙련자', '서비스종사자' 등에서 작업관련 수근관증후군의 비율이 여성에서 유의하게 높게 나타났으나 연령, 비만도 지수, 과거병력 등에 따른 차이는 관찰되지 않았다. 주관적 증상 중에 '손을 많이 사용한 후 심해진다'와 '손을 털면 덜해진다'라는 항목을 작업관련성 수근관증후군 환자에서 더 많이 호소하였고 다른 증상은 별다른 차이를 보이지 않았다. 작업관련성 수근관증후군 환자가 비교적 많이 노출되는 작업은 '지나치게 손을 뻗쳐서 하는 일', '손을 불편한자세로 유지하는 일' 등이었다. 결론: 전체 수근관증후군 중 작업관련성이 있다는 비율이 매우 높은 것을 확인할 수 있었다. 수근관증후군 감시체계가 작업관련성 수근관증후군의 여러 특성을 밝히는데 매우 효과적인 것으로 나타났으나 현재까지는 중재 대상을 구체적으로 특정하기에는 한계가 있다. Objectives: Carpal tunnel syndrome (CTS) is one of the most important work related musculo-skeletal diseases in Korea. However, there are few epidemiologic studies on the work-related CTS (WR-CTS). This study aimed to investigate the epidemiologic characteristics of WR-CTS in Korea. Methods: Data obtained from the "CTS Surveillance System". Physician case-reports in the surveillance were used to document patterns of WR-CTS by age, gender, occupation, sign, symptom, working history. Results: Six hundred and seventy-two cases of WR-CTS were ascertained of which 3 14 with complete information on occupational history were analyzed. It has been estimated that as many as 72% of' all CTS cases are work-related. The highest proportion of WR-CTS was observed in 'elementary occupation workers', followed by 'skilled agricultural, forestry and fishery worker'. The distributions of WR-CTS cases were similar with respect to age, obesity, and past medical history. The proportion of WR-CTS was higher in females. There was no significant difference in physical examination findings between WR-CTS and non WR-CTS cases. Repetitive work and the inappropriate hand posture seemed to be the risks for WR-CTS. Conclusion: WR-CTS is a significant public health problem. The CTS surveillance system is quite useful to elucidate the characteristics of WR-CTS, but it remains of limited use in targeting specific industries and occupations for intervention.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

경피적 전기 신경 자극 전후에 시행한 H-반사 측정치 변화값의 검사자간 변이

노종래,정호중,,하호성 KOSIN UNIVERSITY COLLEGE OF MEDICINE 2006 高神大學校 醫學部 論文集 Vol.21 No.1

Background : This study was designed to research the inter-examiner variability of H-reflex changes by the transcutaneous electrical nerve stimulation (TENS). Materials and Methods : The H-reflexes were recorded in a healthy subjects by a standardized method of Braddom and Johnson. Electromyelogram was performed on a healhty man by 30 examiners. A healthy man were stimulated by TENS for 20 min. The onset latency, amplitude, and H/M ratio of H-reflex were measured before, and immediately, after TENS. Statistical analysis was done with paired t-test and student t-test of SPSS for windows (version 11.0). Result : Onset latency of H-wave and M-wave was significantly delayed immediately after TENS (p<0.05) but H-amplitude, M-amplitude and H/M ratio was not significantly changed (p>0.05). Onset latency of H-wave showed no inter-examiner bias (p>0.05), but H-amplitude, M-amplitude and M-latency showed inter-examiner bias on repeated test (p<0.05). Conclusion : In the H-reflex measurements, only H-latency showed no inter-examiner bias. These results suggest that H-latency can be used as a experimental value, but not H-amplitude, M-amplitude and M-latency. And H- reflex measurements should optimally be performed by a skilled examiner to minimize the degree of variability associated with different examiner.

평택시 미군기지 주변 주민의 비행기 소음과 청각학적 평가결과의 관련성

정종도,김현주,정재윤,노상철,권호장 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.2

목적: 비행기소음이 청각에 대한 포괄적인 영향을 파악하기 위하여 이명 및 난청과의 관련성을 규명하고자 한다. 또한 변조이음향방사 검사를 통해 비행기소음의 난청에 대한 영향을 객관적으로 파악하고자 하였다. 방법: 연구 대상지역은 평택시에 위치한 두 개의 미군기지(K-55, K-6) 주면 8개 마을로 선정하였고 대조지역은 비행장에서 10 km 이상 떨어진 5개 마을이었다. 연구대상은 전도성 난청자와 순음청력검사에 협조가 불가능한 경우를 제외하고 노출군 492명 , 대조군 200명이었다. 환경소음은 2005년 12월 9일, 노출지역 8개, 대조지역 2개 마을을 동시에 주간 8시간 측정하였다. 구조화된 설문지를 통해 이명 여부와 그 불편감을 조사하였고, 이명 불편감은 구조화된 '이명 불편감 설문지'를 통해 파악한 뒤감정적, 기능적, 재앙화적 측면에서의 점수를 합산하여 산출하였다. 청력평가를 위해 0.5, 1, 2, 3, 4, 6, 8 kHz에 대하여 순음청력검사와 1582, 2003, 3175,4007 Hz에 대하여 번조이음향방사 검사를 시행하였다. 비행기소음의 노출특성 및 혼란변수의 성차를 고려하여 성별층화분석을 했고, 연속변수는 일반선형모델(general linear model)을 사용하여, 범주형 변수는 로지스택 회귀분석을 사용하여 분석하였으며, 보정한 혼란변수는 연령, 교육정도, 스트레스 반응척도, 군대소음, 농업소음, 직업소음이었다. 결과: 이명 증상 호소율은 남성에서 노출군 47.3%, 대조군 27.6%이었고, 여성에서 노출군 50.8%, 대조군 28.5%이었으며, 그 대응비는 남성에서 2.06(95% CI:1.09~3.88), 여성에서 1.97(95% CI: 1.17~3.30)이었다. 이명 불편감 영역별 점수는 남녀 모두에서 감정적, 기능적, 재앙화적 측면에서 노출군이 비노출군보다 유의하게 높았다(p<0.001). 순음청력검사결과 남성에서는 우측 귀 0.5, 1 kHz에서, 여성에서는 좌측 귀 0.5, 1 kHz와 우측 귀 0.5, 1, 2, 3, 4, 6 kHz 주파수 영역에서 노출군의 청력역치가 대조군보다 유의하게 높았다(p<0.05). 변조이음향방사 검사결과, 남성에서는 두 군간에 비정상률의 차이가 없었으나, 여성의 비정상률은 좌측 귀 3175, 4007 kHz 영역에서 각각 1.92(95% CI:1.10~3.36), 2.71 (95% CI: 1.49~4.91), 우측 귀 각각 1.73(95% CI: 1.01~2.99), 1.78(95% CI:1.01~3.15)의 대응비를 보였다. 결론: 연구결과 수십 년간 군 기지의 비행기소음에 노출된 집단에서 이명과 이명 불편감이 대조군보다 유의하게 높았다. 순음청력검사는 노출군이 대조군보다 통계적으로 유의한 청력저하를 보였다. 변조이음향방사 검사는 여성 노출군에서만 대조군보다 통계적으로 유의한 비정상률을 보였다. 이로부터 비행기소음이 이명과 난청 등 삶의 질에 영향을 미치는 건강문제를 유발할 가능성을 확인할 수 있었다. Objective: To investigate the relationship between aircraft noise and the results of audiological evaluation on tinnitus and hearing loss among residents near United States military air-bases in Pyeongtaek city. Methods: Residents (n=492) exposed to aircraft noise were selected from eight villages near U.S. military air-bases (K-55 and K-6) in Pyeongtaek city. Residents (n=200) from five villages located at least 10km away from the air-base were selected for the control group. All participants completed a questionnaire on tinnitus and audiological evaluations included pure tone audiometry (PTA) and distortion Product otoacoustic emissions (DPOAE). Statistical analyses involved a general linear model and multiple logistic regression stratified by gender and data was a쏜usted by age, educational level, stress response index and noise type (i.e. military, agricultural and occupational). Results: The equivalent noise levels (Leq) in the vicinity of the air-field were 73.4~81.5 dB (A). Tinnitus prevalence was 47.3% and odds ratio (OR) was 2.06 (95% confidence interval (CI): 1.09-3.88) among noise-exposed males. Tinnitus prevalence was 50.8% and OR was 1.97(95% CI: 1.17~3.30) among noise-exposed females. Tinnitus handicap scores among exposed group were significantly higher in functional, emotional, and catastrophic subclasses (P<0.001). PTA revealed hearing thresholds among the exposed group of 0.5 and 1 kHz (male right ear), 0.5 and 1 kHz (female left ear) and 0.5, 1, 2, 3, 4 and 6 kHz on female right ear that were significantly higher than those of the unexposed group. No Significant difference in DPOAE was observed among noise-exposed mes. However, significant differences were evident for noise-exposed females at 3175 and 4007 Hz. ORs of right female ears 3175 and 4007 Hz were 1.73(95% CI: 1.01-2.99) and 1.78(95% CI: 1.01-3.15). ORs of left female ears at 3175 Hz and 4007 Hz were 1.92(95% CI: 1.10-3.36) and 2.71(95% CI: 1.49-4.91) Conclusions: Aircraft noise may adversely affect hearing function and tinnitus.

側腦室內 d-Tubocurarine이 家兎 腎臟機能에 미치는 影響

盧熙壯,許康敏,李載欣,昔廷鎬 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1

Effect of d-tubocurarine administered intracerebroventricularly on the renal function of rabb-its was investigated. 1) Intraventricular d-tubocurarine induced decrease of urine flow, renal plasma flow, glomerular filtration, and urinary sodium and potassium excretion, but increase of reabsorption of urinary sodium and potassium. 2) Correlation coefficient between changes of two parameters among urine volume, renal plasma flow, glomerular filtration and urinary sodium excretion was statistically significant. 3) Changes of various parameters of renal function induced by intraventricular d-tubocurarine were inhibited by phenol treatment on the renal artery except change of sodium. From the above results, it is suggested that the effect of intraventricular d-tubocurarine on the renal function of rabbit is due to renal hemodynamic changes by central sympathetic activation.

휘트니스 센터의 서비스 품질이 고객만족과 재구매 의도에 미치는 영향

김정훈,노영태,김성호,서봉한 釜山大學校 附設 體育科學硏究所 2004 體育科學硏究所 論文集 Vol.20 No.-

The purpose of this study was fitness club's services quality, the satisfaction of client, the record re-purchasing of client, to check connection was to supply primary data which was new clients occurred and the clients satisfied....

Antioxidant and Anti-Inflammatory Effects of Rhei Rhizoma and Coptidis Rhizoma Mixture on Reflux Esophagitis in Rats

Kwon, O Jun,Kim, Min Yeong,Shin, Sung Ho,Lee, Ah Reum,Lee, Joo Young,Seo, Bu-il,Shin, Mi-Rae,Choi, Hyun Gyu,Kim, Jeong Ah,Min, Byung Sun,Kim, Gyo-Nam,Noh, Jeong Sook,Rhee, Man Hee,Roh, Seong-Soo Hindawi Publishing Corporation 2016 Evidence-based Complementary and Alternative Medic Vol.2016 No.-

<P>The purpose of this study was to investigate the antioxidant and anti-inflammatory effects of the combined extract of Rhei rhizoma and Coptidis rhizoma (RC-mix) in experimental model of acute reflux esophagitis. The antioxidant activity was assessed by<I> in vitro</I> 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. RC-mix was given at 100, 200, and 400 mg/kg body weight 2 h prior to induction of reflux esophagitis (RE). After 5 h, the effects of RC-mix treated rats were compared with those of normal and control rats. The representative flavonoid contents of RC-mix, such as sennoside A, epiberberine, coptisine, palmatine, and berberine, were detected using HPLC. The elevated esophageal mucosa damage was markedly ameliorated by RC-mix treatment in a dose-dependent manner. Furthermore, the administration of RC-mix reduced the increase of serum reactive oxygen species (ROS) and peroxynitrite (ONOO<SUP>−</SUP>). The improvement of superoxide dismutase (SOD) and heme oxygenase-1 (HO-1) levels were marked in the group given RC-mix. Moreover, the elevation of inflammatory mediators and cytokines by nuclear factor-kappa B (NF-<I>κ</I>B) activation in control rats decreased by RC-mix pretreatment. These results indicate that RC-mix treatment reduces the pathological states of esophagitis<I> via</I> regulating NF-<I>κ</I>B mediated inflammation related to oxidative stress. </P>

The Accumulating Aspect of Sugar and Organic Acid in Greenhouse Strawberry

Ho Jeong Jeong,Jae Woan Cheong,Il Rae Roh,Yong Seop Cho 한국원예학회 2008 한국원예학회 기타간행물 Vol.- No.-

Chimera Type of Sports from ‘Campbell Early’ Grape

Jeong Ho Roh,Kyo Sun Park,Hae Keun Yun,Han Ik Jang,Seok Tae Jeong 한국생물환경조절학회 2007 한국생물환경조절학회 학술발표논문집 Vol.16 No.2

Guidelines for Mobile Laboratories for Molecular Diagnostic Testing of COVID-19

Roh Kyoung Ho,Hong Ki Ho,Nam Myung-Hyun,Kim Taek Soo,Seong Moon-Woo,이진경,Bae Sookyoung,Huh Hee Jae,Ahn Jeong-Yeal,Lim Jinsook,Kim Gab Jung,Park Jae Sun,Kim Hyun Yeong,Yoo Cheon Kwon,Lee Hyukmin 대한진단검사의학회 2022 Annals of Laboratory Medicine Vol.42 No.5

With the rapid spread of the coronavirus disease (COVID-19), the need for rapid testing and diagnosis and consequently, the demand for mobile laboratories have increased. Despite this need, there are no clear guidelines for the operation, maintenance, or quality control of mobile laboratories. We provide guidelines for the operation, management, and quality control of mobile laboratories, and specifically for the implementation and execution of COVID-19 molecular diagnostic testing. These practical guidelines are primarily based on expert opinions and a laboratory accreditation inspection checklist. The scope of these guidelines includes the facility, preoperative evaluation, PCR testing, internal and external quality control, sample handling, reporting, laboratory personnel, biosafety level, and laboratory safety management. These guidelines are useful for the maintenance and operation of mobile laboratories not only in normal circumstances but also during public health crises and emergencies.