기관지 방선균증의 임상 1례

이은영,장태원,정만홍,옥철호,이규원,손창배,이지숙,신은경,서정아,백종현,김영옥 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Actinomycosis is a chronic suppurative infection, whitch infiltrates mucosa-associated tissues. Thoracic, pelvic and cervicofacial infections of actinomyces are not uncommon, but endobronchial actinomycosis is rarely reported. We report a case of a 29 year old man who presented with a recurrent pneumonia and chronic cough. Fiberoptic bronchoscopy revealed occlusion of the right. lower medio-basal segment bronchus with exophytic endobronchial mass. The diagnosis was confirmed histologically by demonstration of sulfur granules in the bronchoscopic biopsy of the mass. Intravenous administration of amoxacillin and clindamycin followed by oral amoxacillin and clindamycin therapy resulted in complete recovery.

Gesture, Gaze, and Bodily Cues in Mandarin Conversation: Two Case Studies

Lee,Jee-won 한국사회언어학회 2012 사회언어학 Vol.20 No.1

Lee, Jee-won. 2012. Gesture, Gaze, and Bodily Cues in Mandarin Conversation: Two Case Studies. The Sociolinguistic Journal of Korea 20(1). pp. 213-234. This study uses discourse analysis to illustrate some ways that non-verbal actions such as gaze, facial expression, and gesture work to contextualize the speech delivered in conversation. These bodily cues also enable participants to organize interactions as collaborative creations of meaning rather than simply a turn-by-turn exchange of speech. This study uses two excerpts from Mandarin Chinese conversations to illustrate how non-verbal cues help speakers and recipients to engage in collaborative action with one another. Speakers give recipients information about their stances vis-à-vis the speech they produce, and recipients use this information to manage their reactions to the speech they hear. Non-verbal actions also allow both parties to mutually regulate the flow of conversation. In both examples, it becomes clear that gaze, facial expression, and gesture are important elements of spoken interaction and that conversation as a whole should be understood as a contextual web of meaning that includes speech, body language, and overall social interaction.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

Genetic Characterization of Haemagglutinin 1 Domain of Influenza B Viruses Isolated in Korea during $1988{\sim}1999$

Shin, Gu-Choul,Na, Byoung-Kuk,Lee, Joo-Yeon,Ahn, Jung-Bae,Park, Jong-Won,Lee, Jin-Soo,Kim, Jee-Hee,Kim, Woo-Joo,Kang, Chun The Korean Society for Microbiology 2003 Journal of Bacteriology and Virology Vol.33 No.4

Although Korean influenza virus isolates have been genetically associated with the vaccine strains of the corresponding year, influenza B viruses have prevailed almost every year in Korea during the past decades. We have 'analyzed the genetic characteristics and evolutionary patterns of the haemagglutinin (HA) 1 domains of influenza B viruses isolated during 1988-1999 using direct RT-PCR and sequencing. Phylogenetic analysis of influenza B viruses isolated in Korea indicated that antigenically and genetically distinguishable strains of the lineage II and lineage III variants had been cocirculated. Variants prevailed in early 1990s are represented in 1996/97 and 1998/99 and some different variants have been co circulated geographically and prevailed concurrently in Korea. All HA1s of Korean isolates have amino acid substitutions mainly in the region between position 124 and 310, which was previously proposed an immunodominant region. Insertion-deletion patterns of the HA gene revealed that Korean influenza B viruses were evolved from Lee40 with different manner between lineage II and III viruses. Lineage III viruses were also divided into two groups as conserved group and inserted group, in relation to Lee40. But lineage II viruses had evolved with directional pattern. Antigenic index proposed that influenza B isolates prevailed since 1996/97 seasons might had emerged from the antigenic variants of a Seo1697-like virus and that new variants might appear from the lineage II viruses resulting in persistent prevalence in Korea.

C_57BL/6계 생쥐와 Nude계 생쥐의 오금림프절내 림프소절 및 종자중심의 분포에 관한 3차원적 연구

지연근,이원규,안희경 慶熙大學校 1992 論文集 Vol.21 No.-

This study was aimed to clarify the distribution of lymph follicles and germinal centers in the lymph nodes of the C_57BL/6 and nude strain mice. Male adult mice were used in this study. After animal were sacrificed, the right popliteal lymph nodes were removed and fixed in Zenker-formol solution for 3 hours and embedded in JB-4 resin. One of every two section, cut 3㎛ in thickness serially, was stained with May-Gru‥nwald and Giemsa solution. The results obtained from this study were as follows; 1. The number of lymph follicles per popliteal lymph node was average 11.25 C_57BL/6 mice but, the number of lymph follicles in nude mice was 20.25. In C_57BL/6 mice major distribution(8.5) of the lymph follicles situated in peripheral cortex overlying the unit(PCOU). In unde mice major distribution(14) is peripheral cortex beyond the unit(PCBU). 2. The thickness of most lymph follicles was between 0.01-0.19 mm in C_57BL/6 mice. But in nude mice the thickness of most of lymph follicles was between 0.20-0.39mm 3. The number of lymph follicies contained germinal center was 8.75 in nude mice. But C_57BL/ 6 mice was not observed germinal centers. 4. The average number of deep cortex is 1.5 and shape is semiovoid in C_57BL/6 mice. Spherical shaped deep cortex was observed and the number of that is one in nude mice. In stained section low density deep cortex was observed in nude mice specifically. 5. The size of lymph follicle in C_57BL/6 mice is 0.405mm and in nude mice 0.795mm

공작기계 열변위 보정에 관한 연구

이인재,최영휴,정원지 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.4

This paper presents an indirect compensation of thermal errors during machining, in which thermal error is modelled as a linear regression of temperatures measured at 4 specified positions. In this regression model, weighting coefficients of the measured temperatures were estimated by using the least square method. The grinding test with compensation, after 4-hour warming-up operation before the test, showed that the maximum machining error of the work pieces was reduced to 12㎛ while it measured by 28㎛ without compensation. Furthermore the standard deviation of machining errors was also reduced from 8㎛ to 2㎛.

화상에 관한 임상적 연구 : 142 Cases

이지원 충남대학교 의과대학 지역사회의학연구소 1979 충남의대잡지 Vol.6 No.2

142 cases of the burn patients experienced at the department of General Surgery, Chungnam National university Hospital, for 4 years from 1975 to 1978, were analysed. The results are as follows ; 1. The incidence of the burn has been increased every year and the mean incidence was 5.7% of all the admitted patients at the department of General Surgery. 2. The incidence of the adult to the pediatric group was almostly similar. The incidence of the male to the female was almostly similar in the pediatric group, but 1.7 times more frequent in male. 3. The burn patients were most common in Octber, August and September, and seasonally in Summer(33.6%). 4. The most common cause of burn was the flame burn(57.8%). The other causes were the scald burn(35.2%), the electrical burn(3.5%), the contact burn(2.1%), and the chemical burn(1.4%). 5. The precipitating causes were the pediatric's accident(38.8%), industrial accident (27.5%), the raw manipulaton of the alcohol burner in the camping(15.7%), the incidental accident during sleeping(10.6%), suicidal behavior(4.9%), and others(1.4%) in order. 6. The mortality was 11.9%(17cases) of all the burn patients, and increased in proportion to the burn ranget. The causes of death were inadequate fluid therapy and septicemia 7. In the bacteriologic cultures of the burn areas, the positive rate was 58.3%(7 cases), and among them, Pseudomonas aeruginosa was cultured in 42.9% and Staphylococcus aureus in 28.6%. 8. The frequently involved areas were the arm(60.5%) and the face(59.2%). 9. The most commonly used drug for treatment was 0.5% AgNO_3 solution(33.5%). The effect for the prevention of the infection was best in 0.5% AgNO_3 solution (infection rate : 67.8%). 10% Sulfamylon cream was an also an effective drug(infection rate : 75.0%). 10. The common complications of 71 cases, except selfdischarge, were local infection (85.9%), joint stiffness(76.1%), renal failure (16.9%), septicemia(7.1%), Marjolin's ulcer(5.6%), and others(2.8%).

건전지의 본질안전 방폭성 평가에 관한 연구

지승욱,이광식,이동인,박원주,이춘하,김하호 嶺南大學校 工業技術硏究所 1997 工業技術硏究所論文集 Vol.25 No.1

Ignitability of explosive gas mixture by spark of dry cell in case of short circuit by accident was studied for the purpose of evaluation of intrinsically safe characteristics of dry cell that manufactured in Korea. IEC type spark test apparatus, 21±2[vol%] of hydrogen-air mixture, and dry cell that produced in Korea was used for the experiment. The result of this research could be used for design, manufacturing and using the intrinsically safe electrical apparatus.

難治結核患者의 喀痰과 肺切除組織에 對한 細菌學的 硏究

이지원,이영 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1

The prevalence and drug resistance of M. tuberculosis are still very high as indicated in the 1980 prevalence survey. The spread of drug resistant bacteria is main contemporary health problem in Korea. It is associated with a high rate of treatment failure due to improper use or ineffective chemotherapy and a wide use of corresponding drugs. The author attempted bacteriological studies on the 138 sputums and 48 resected lung tissues from intractable tuberculosis patients who have been hospitalized in Kongju National Hospital (located at Kongju, Chungnam). The results were summarized as follows: 1. Out of 186 tuberculosis patients, Male patients(59.1%) were slightly more than female (40.9 %) and age group of 20-49 years was 82.3% of the total. 2. The number of patients who have been suffering from pulmonary tuberculosis more t han 6 years was 108(58. 1%). 3. Out of 48 operated patients, 27(56.3%) had received pneumonectomy, 16(33. 3%) had received lobectomy, and 5(10.4%) had received decortication. 4. Out of 138 sputum specimens from unoperated patients, 122(88.4%) were positive by culture, and by microscopy 103(74.6%) on direct smear, and 116(84. 1%) on centrifugate smear. 5. Out of 48 operated patients, those negative patients on direct smear of sputums before operation but positive on centrifugate smear of resected lung tissues were 14(29. 2%) and positive patients on centrifugate smears of resected lung tissues but negative by culture ware 11(22.9%). 6. All of the isolated 140 strains were identified as M. tuberculosis and no atypical mycobacterium was isolated. 7. Out of 48 resected. lung tissue specimens, aspergillus species were isolated from 2(4.2%) and Candida albicans was isolated from 1(2. 1%). 8 Out of 137 isolated M. tuberculosis, 99.3% was resistant to one or more drugs and resistance to INH, PAS, SM, EMB and RMP were 93. 1%, 40. 1%, 59. 1%, 56.9% and 71.5%, respectively.

Sporothrix schenckii와 관련주에 대한 Random Amplified Polymorphic DNA (RAPD)분석

이지범,김민,이승철,원영호,김영표 대한의진균학회 2000 대한의진균학회지 Vol.5 No.3

Background: Sporotrichosis is a common deep cutaneous fungal disease caused by Sporothtix (S.) schenckii. The recent development of polymerase chain reaction (PCR) technology, in particular, arbitrarily primed PCR (AP-PCR) or random amplified polymorphic DNA (RAPD), has greatly enhanced the molecular detection and identification of various pathogenic agents, including fungi. Objective: This study was aimed to differentiate Sporothrix schenckii, and related fungi such as S. schenckii var. luriei, S. flocculosa, S. nivea, Ophiostoma stenoceras, and clinical isolates on the basis of distinct DNA band patterns in the RAPD. Methods: S. schendcii, S. schenckii var. luriei, S. flocculosa, S. niveㅁ, Ophiostoma stenoceras from ATCC and KCCM, and clinical 10 isolates from Chonnam University Hospital were used for RAPD analysis. For RAPD, 3 random primers were used. Genomic DNA was extracted by Liu method. Amplification reactions were performed in volumes of 50 μL containing 10 mM Tris-HCI (pH 8.3), 50 mM KCl, 1.5 mM MgCl2, 0.1% Triton X-100, 200μM dNTP mixture, 40 pM primer, 1 U of Taq polymerase, DNA 20 ng. Results: 3 decamers (5'-TGCCGAGCTG-3', 5'-AGTCAGCCAC-3', 5'-AATCGGGCTG-3') are generated in the RAPD, distinct DNA products from S. schenckii forming characteristic band patterns upon gel electrophoresis. Each random primer amplified characteristic same band patterns in DNA from clinical 8 isolates among 10 isolates, 2 isolates have different DNA band patterns. These results suggest of being a Sporothrix anamorph different from S. schenckii in Korea. Conclusion: With 2 random primers (5'-TGCCGAGCTG-3', 5'-AGTCAGCCAC-3') S. schenckii and related fungi investigated produced distinct DNA band patterns on gel electrophoresis. The RAPD was a very valuable laboratory method for identification of S. schenckii isolates. [Kor J Med Mycol 5(3): 113-119]