Canine juvenile cellulites의 진단과 치료 증례

황철용,유종현,강형석,윤화영,한홍율 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.4

Canine Juvenile cellulitis was diagnosed in 2 puppies hospitalized in Veterinary Medical Teaching Hospital of Seoul National University. Characterized dermatological problems were presents of scale, crust, purlent exudation and alopecia limited on their face. On cytologic examinations of direct impression smears for the lesions, numerous neutrophils and macrophagies were observed. No bacteria and fungus were noted. Treatments with administration of predinisolone and antibiotic orally combined with topical shampoo treatment had good results for the two puppies.

EMLA Cream 도포와 1% Lidocaine 침윤 후 요골동맥천자시 진통정도의 비교

윤석화,황원재,최세진 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

In a double blind study, the efficacy of topical 5% EMLA cream was compared with that of 1% lidocaine infiltration in the pain-relief and incidence of complication after radial arterial cannulation. Forty three premedicated adults were allocated randomly to two groups to receive EMLA cream and 1% lidocaine infiltration. Following arterial cannulation, pain was assessed by the patient using visual analogue score (VAS) and by a independent observer using four-caregory verbal rating score (VRS). There no significant differences between the EMLA group and 1% lidocaine infiltration group both patient and observer assessments. Compared with lidocaine infiltration group, significantly lower trial numbers of puncture in those recieving EMLA cream group, but no difference of discomfortness of puncture were observed in EMLA cream group.

직업적 연폭로에서 혈중 연량 수준에 따른 선별검사로서의 혈중 ZPP 검사의 타당도

한구석,안현철,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

In order to evaluate the validity of current screening criteria of lead exposure and to provide effective information for the better health management of lead workers, author investigated the interrelationship between blood lead and blood zinc protoporphyrin(ZPP) and evaluate the validity of blood zinc protoporphyrin as the screening test and blood lead as gold standard of diagnostic test. The total of 2245 lead workers (male workers: 1982, female workers : 263) from 12 lead using industries were studied. Blood lead, ZPP, hemoglobin and hematocrit were selected as lead exposure variables. Personal information on sex, age and work duration were also checked. Blood lead was measured with flameless atomic absorption spectrometry (model: Hitachi 8100) using standard addition method. Blood ZPP was measured with portable hematoflurometer (model: Aviv 206). The results obtained were as follows: 1. The mean blood lead of all lead workers were 0.7±14.3㎍/㎗(Male: 31.0±14.4㎍/㎗, Female: 28.2±12.9㎍/㎗), whereas the mean blood ZPP of those were 68.1±47.5㎍/㎗(Male: 63.9±43.7㎍/㎗, Female: 100.1±61.0㎍/㎗). The mean value of hemoglobin and hematocrit of all lead workers were 14.5±1.5g/㎗(Male: 14.7±1.3g/㎗, Female: 12.3±1.2g/㎗) and 45.4±3.6(Male: 46.2±2.8, Female: 39.5±3.1) respectively. 2. Validity of test using blood zinc protoporphyrin as screening test for blood lead levels of 30㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 50 and 90 ㎍/㎗ of ZPP respectively, showing 50 and 60 ㎍/㎗ of ZPP for all lead workers. While those test for blood lead levels of 40㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 and 90 ㎍/㎗ of ZPP respectively, showing 60 ㎍/㎗ of ZPP for all lead workers, those test for blood lead levels of 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that the highest validity value for male and female lead workers were 60 or 70 and 100 ㎍/㎗ ZPP respectively, showing 60and 70 or 80 ㎍/㎗ of ZPP for all lead workers. 3. Predictive value of test using blood zinc protoporphyrin as the screening test for different blood lead levels of 30, 40, 50 and 60㎍/㎗ as gold standard of diagnostic test revealed that positive predictive value of screening test were decreased by the increase of blood lead level regardless of csreening criteria value ZPP and negative predictive value of screening test were increased accordingly regardless of screening criteria value of ZPP. On the other hand, within same blood lead level as a gold standard positive predictive values were inceased by the increase of screening criteria value of ZPP, whereas the negative predictive value were decreased accordingly by the the increase of screening criteria value of ZPP. 4. The correlation analysis of all lead workers among study variables revealed that CPbB and natural log transformation ZPP(LZPP) were better correlated with other variables and found to be better estimate than PbB and ZPP themselves. The age was correlated with all other variables, but the work duration was not. The correlation analysis of male and female workers among study variables revealed the same results with all lead workers. 5. The slope of simple linear regression of CPbB (independent variable) with ZPP in female workers(3.223)was steeper than in male workers(2.144). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But there was no slope difference between two groups divided by their work duration of 2 years less and more. The slope of simple linear regression of CPbB lead (independent variable)with ZPP in lead workers whose blood lead were higher than 30㎍/㎗and 40㎍/㎗ were steeper than those whose blood lead were less than 30㎍/㎗ and 40㎍/㎗. 6. The slope of simple linear regression of CPbB (independent variable) with ZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead. 7. The slope of simple linear regression of CPbB (independent variable) with LZPP in female workers(0.0308was steeper than in male workers(0.0253). That of lead workers with work duration of less than 1 year was steeper than that of lead workers whose work duration was more than 1 year. But where was no slope difference between two groups divided by their work duration of 2 years less and more. While the slope of simple linear regression of CPbB lead (independent variable) with LZPP in lead workers whose blood lead were hogher than 30㎍/㎗ was not steeper than those whose blood lead were less than 30㎍/㎗, there was no slope difference between two groups whose blood lead were less than 40㎍/㎗ and more than 40㎍/㎗. 8. The slope of simple linear regression of CPbB (independent variable) with LZPP in lead industries with low mean blood lead were less steeper than those with high mean blood lead, but the difference was not significant then that of CPbB and ZPP. With above results, it is recommended that the screening criteria value of ZPP should be down to 60-70㎍/㎗ from 100㎍/㎗ for male lead workers and screening criteria of ZPP for female lead workers was all right with current value of 100㎍/㎗. So it is recommended to make different screening criteria of ZPP for male and female workers like the hemoglobin and hematocrit screening criteria. It is also preferable to use CPbB and LZPP rather than uncorrected PbB and ZPP in the evaluation of lead exposure for lead workers.

Urapidil, Labetalol의 투여가 기관내 삽관시 심혈관계에 미치는 영향

신용섭,윤석화,손수창,이원형,이정은,황원재,김만수,김영주,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

We have examined the comparative efficacy of small doses of intravenous urapidil and labetalol in blunting hemodynamic response to endotracheal intubation and surgical incision in 30 patients without cardiovascular diseases. After intravenous urapidil 0.2 mg/kg or labetalol 0.2 mg/kg anesthesia was induced with thiopental 5mg/kg. Endotracheal intubation was facilitated by vecuronium 0.15 mg/kg with priming principle and anesthesia was maintained with enflurane and nitrous oxide in oxygen. Systolic, diastolic and mean arterial pressure and heart rate were measured before administration of the drugs, 5 minute after administration, just prior to endotracheal intubation and 1, 3, 5, 10 minute after intubatin. Also the peak blood pressures and heart rate within 10 minutes after surgical incision were measured. Endotracheal intubation and surgical stimulation were associated with significant increases in blood pressures and heart rate in both urapidil and labetalol group. Comparison of the changes in systolic, diastolic, and mean artrial pressures and heart rate between urapidil and labetalol group showed no significant difference except peak systolic pressure after surgical incision. It is concluded that the pressor response to endotracheal intubation and surgical stimulation are not influenced significantly by urapidil 0.2 mg/kg or labetalol 0.2 mg/kg. However, urapidil and labetalol preloading may be similarly effective in the blunting of the increases in blood pressures with larger doses of the durgs during anesthetic induction.

안동국제탈춤페스티벌의 거버넌스 특성과 평가

황화석(Hwa Seok Hwang),이철우(Chul Woo Lee) 한국지역지리학회 2012 한국지역지리학회지 Vol.18 No.2

본 연구는 안동국제탈춤페스티벌의 거버넌스의 특성을 분석하고 평가하였다. 평가는 사회적 정당성, 신뢰성, 전 문성 그리고 투명성의 4가지 요소별로 거버넌스 주체 상호간 교차평가에 초점을 두었다. 안동국제탈춤페스티벌의 핵 심적인 성공요인으로는 축제 주체 간의 협력적 파트너십에 기초한 거버넌스를 들 수 있다. 2011년 현재 안동국제탈춤 페스티벌의 거버넌스는 ``안동축제·관광조직위원회``를 중심으로 축제전문가, 시민사회단체, 지역상공인단체, 자원봉사자 그리고 지방정부 등의 각 주체들이 수평적이고 개방적인 파트너십에 기초한 소위 ``민간주도형`` 거버넌스를 그 특성으 로 들 수 있다. 안동국제탈춤페스티벌의 거버넌스는 투명성을 제외하고는 모든 구성요소에 대하여 긍정적인 것으로 평가되었다. 거버넌스에 대하여 긍정적으로 평가한 경향이 강한 주체는 축제를 주도적으로 기획, 집행 그리고 평가 과 정에 참여한 주체이었다. 긍정적으로 평가한 이유는 사회적 정당성의 경우에는 사업에 대한 정당성과 관련 주체의 참 여 보장, 신뢰성에 있어서는 주체의 능력과 인지 및 제도적 신뢰이었다. 전문성의 경우는 전문지식, 대안제시 능력 그 리고 업무의 지속성이었고, 투명성에 있어서는 원활한 의사소통과 정보 공개 및 공유 보장이었다. 앞으로 거버넌스의 효율성을 제고하기 위해서는 상대적으로 한정적인 역할을 수행하였던 주체의 적극적인 참여와 주체 간 그리고 주체와 일반시민 간의 원활한 의사소통과 정보공유를 보다 강화하기 위한 대안이 마련되어야 할 것이다. This paper evaluates the governance of the Andong International Mask Dance Festival. The evaluation focuses on mutual cross-assessment of agents engaging in governance relating to four elements: social justification, reliability, professionalism and transparency. Governance based on co-operative partnership was the essential factor leading to the mask festival`s success. Governance of the Andong International Mask Dance Festival in 2011 was privately initiated governance having horizontal and open partnership among festival specialists, civil society organizations, regional business organizations, volunteers and local government, with the Andong Festival Tourism Foundation as the central figure. Three of governance elements were successfully carried through; the exception was transparency. The agents who gave more positive evaluations were those who played leading roles in planning and conducting events, as well as in assessing those events. The reasons for positively assessing the elements are the significance of the festival and the guarantee of agents` participation in social justification; the ability of agents, as well as cognitional and institutional trust in reliability; expert knowledge, capacity to suggest alternatives and duality of business in professionalism; and effective communication, the guarantee of opening of information and information sharing in transparency. To improve the effectiveness of governance, the system for allowing passive agents to contribute usefully should be strengthened. Mutual communication and sharing of information among agents, as well as between agents and residents, also should be more strongly reinforced.

중대규모 지중 계간축열 시스템의 해석적 연구

황석화(Seok Hwa Hwang),이재우(Jae Woo Lee),허재혁(Jaehyeok Heo),김민휘(Minhwi Kim),윤린(Rin Yun) 대한설비공학회 2018 대한설비공학회 학술발표대회논문집 Vol.2018 No.11

축제참가자의 지역축제 의의에 대한 인식과 평가에 관한 연구

황화석(Hwang, Hwa-Seok) 한국지역지리학회 2015 한국지역지리학회지 Vol.21 No.2

「안동국제탈춤페스티벌2011」을 대상으로 축제참가자의 지역축제 의의에 대한 인식과 평가에 관해 연구 하였다. 연구결과는 먼저, 안동국제탈춤페스티벌에 참가한 축제참가자들의 인구학적 특성은 대졸학력의 20~40대 연령층과 가 족단위의 방문객이 주를 이루었으며, 외지인과 지역주민 간의 인구학적 특성의 차이는 거의 나타나지 않았다. 둘째, 지역축제 특성에 대한 인식을 알아보기 위해 실시한 설문조사 결과, 지역축제가 지역문화자원 활용정도와 지역축제의 주제 반영정도에 대하여 두 집단 모두 긍정적으로 응답하였다. 주제의 반영정도는 지역주민들의 사례축제에 대한 긍 정적인 인식이 보다 높은 것으로 나타났다. 셋째, 지역축제의 의의는 지역주민 화합, 지역 경제활성화 그리고 지역 홍 보 및 지역 이미지 제고이다. 여기서 지역주민과 외지인들은 지역 홍보 및 이미지 제고를 가장 긍정적으로 인식한데 비해 지역주민 화합에는 다른 설문항목에 비하여 긍정적인 인식이 낮았다. 따라서, 사례축제가 보다 지역사회에 깊게 뿌리내림 하기 위해서는 축제를 통한 지역주민들의 문화적인 삶의 질을 향상시키고 주민들의 적극적인 참여를 보다 유도할 필요성이 있다. 그에 대한 개선방안으로 지역주민들을 위한 프로그램마련과 축제의 기획, 집행, 평가 과정에서 지역주민들의 참여가 가능한 다양한 창구를 마련하여 지역주민들의 참여를 확대할 것을 제시한다. This paper is investigated to awareness and assessment by festival participants’ to significance of lacal festival in 「Andong International Mask Dance 2011」. As results, first, demographic characteristics of festival participants’ in case study are that dominated participants’ were tewnties to fourties consisting consanguine and graduates. There is almost same rate in demographic characteristics. Second, the results of questionnaire for characteristics of local festival are that positive responds was dominated at degree of using and respect of local culture resources and main theme reflected to festival. Third, questionnaire items of the significants of local festival are participation desire and real participation rates of citizen to local festival, contribution rate of citizenry reconciliation, effects of regional marketing and increasing regional image, local economy development and rate of improving people’s quality of cultural life. In these item, effects of reginal marketing is most positive response by Andong citizen and outsiders. And positive response of economical effects is higher outsiders then citizen. However, the contribution rate of citizenry reconciliation is lower then other items to positive response. Therefore, methods of regoinal embeddedness of case festival are evaluating life quality of local citizen by local festival and leading active participation of local people to local festival.

Microwave Fabrication of MFI Zeolite Crystals with a Fibrous Morphology and Their Applications

Hwang, Young Kyu,Chang, Jong-San,Park, Sang-Eon,Kim, Dae Sung,Kwon, Young-Uk,Jhung, Sung Hwa,Hwang, Jin-Soo,Park, Min Seok WILEY-VCH Verlag 2005 Angewandte Chemie. international edition Vol.44 No.4

<B>Graphic Abstract</B> <P>Metal incorporation and synthesis of MFI zeolites with microwave irradiation result in crystal stacking in one direction to form a fibrous morphology (see images of the Ti-MFI zeolite). These materials display several interesting physicochemical properties including lower packing density and higher hydrophobicity than their nonfibrous counterparts, and as a result, enhanced catalytic properties and increased shape-selective adsorption. <img src='wiley_img/14337851-2005-44-4-ANIE200461403-content.gif' alt='wiley_img/14337851-2005-44-4-ANIE200461403-content'> </P>

아리스톨로크산 함유 생약제에 대한 안전성평가연구 : 3개월간 반복투여독성시험을 통한 신장독성평가

황명실,박미선,문지영,이지선,염영나,이효민,신동환,강진석,윤은경,최미나,육미영,장동덕,길광섭,김승희,양기화 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

본 실험에서는 아리스톨로크산을 함운하고 있는 생약제중 하나인 마두령(.4risfoforfioe JTurruf)의 90일 반복투여독성시헌을 실f,」하였다. 마두령에서 아리스톨로크산을 정량분석한 결과 마두령 단일 건조븐말의 경운 2.112mg/g, 잉상에서 처방되고 있는 마든령복방 (마두령외 9가지 생약제 복합처방) 건조분말꼭 경무에는 0.066m9/5으로 각각 검출되었다. 본 실험에서 용량설정은 마두령 처리군 (저용량 군; 21.3m9/k9/day (임상용량), 중용량군; 2t3mgfg/day, 고용량군; 2430mg딘g b.w./day), 마두령복방 처리군 (427mg/kg b.w./da?; 임상용량) 및 positive control (아리스톨로크산) 처리군 (저용량군;0.05mgag/da17, 중용량군; 0.Smg/kg/day, 고용량군; 5mg./kg/dal·1으료 하여 랫드에게 경구투여하였다. 마두령단방 처궈근 및 마두령복방 처리군에서 저용량군과 중응량군에서는 잉상관찰 및 생화학적 분석에서 패조군과 유의적인 차이가 없었다. 그러나 마두령단방 고용량근에서는 간, 신장의 상대적인 무계가 증가되었고, 신장의 유두이행상피증식 및 암종이 관찰되었으며, 위에서는 편평세포암종이 관찰되었다. 하자만 간손상이나 간암은 유발하지는 않는 것으로 판단되었다. 결론끌으로 본 실험의 결과에서는 아리스톨로크산 함유 생약제인 마두령이 임상용량인 저응량 처리군에서는 독성을 나타내지 않았으나, 고용쏭으로 장기 복용시켰을 깅우 설치류의 전위부위 및 신장에서 독성이 있음을 알 수 있었다. Chines herbs nephropathy (CHN) has been described in young women who had taken a slimming pills containing some chines herbs. Aristolochic acid (AA), suspected substance as the causal factor of CHN, is known a carcinogen. The Aristolochiae fructus (fruit of Aristolochia contorta) was used in Korean Traditional Medicine consists of appropriate amounts of mixed natural products. Subchronic toxicity of A. furctus containing aristolochic acid was investigated in SD rats. The body weight and clinical signs were observed after orally administration of A. futctus at doses of 21.2, 213, and 2130 mg/kg/day; mixture (including 9 other herbs) at dose of 427 mg/kg/day; aristolochic aicd (Ⅰ+Ⅱ) at doses of 0.05, 0.5, and 5 mg/kg/day for 3 months. At the end of the treatment, high dose treated animals revealed a deficit in final body weight about 25% compared with that of control. Organ weights of kidney, liver, testis, or ovary were increased with dose dependent manner. No changes considered to be due to the administration of A. furctus, mixture or aristolochic acid were in hematological and clinical study. However, significant changes at histopathological study of kidney and stomach were boserved in high-dose treated groups. In conclusion, for human health safety it needs appropriate regulatory actions regarding the use of natural herbal medicines known or suspected of containing aristolochic acid.

Design and Implementation of Web-based BGP Analysis and Visualization System Tool on KOREN

Seok-Hoon Choi,Se-Jung Jung,Ji-Tae Shin,Seo-Mee Choi,Dae-Young Kim,Hyun-Ryong Lee,Jong-Won Kim,Jae-Hwa Lee,Sung-Joon Hwang,Chul-Hee Kang 한국통신학회 2004 한국통신학회 학술대회논문집 Vol.2004 No.11