유도무기 통합최적설계를 위한 데이터베이스 설계 연구

이재우,이승진,최석민,조국현,김광식,이정욱,정갑주,Lee, Jae-Woo,Lee, Seung-Jin,Choi, Seok-Min,Cho, Guk-Hyun,Kim, Kwang-Sik,Lee, Jeong-Oog,Jung, Karp-Joo 한국전산구조공학회 2008 한국전산구조공학회논문집 Vol.21 No.6

In this paper, the missile database system for the multidisciplinary design and optimization framework has been designed and investigated. The requirements of the missiles database are analyzed and the database design concept has been defined first. The data flow among the analysis disciplines is investigated and the Entity-Relation diagram is constructed to develop the database table and to define the database schema. The developed database system is integrated into the missile design framework to perform the store, search and management of the design data during the design and analysis of the missile development, hence the efficiency and validity of the database designed in this study has been demonstrated.

휴대형 후두 스트로보스콥의 개발

이재우,권순복,이병주,이진춘,고의경,전경명,왕수건,노정훈,Lee, Jae-Woo,Kwon, Soon-Bok,Lee, Byung-Joo,Lee, Jin-Choon,Goh, Eui-Kyung,Chon, Kyong-Myong,Wang, Soo-Geun,Ro, Jung-Hoon 대한후두음성언어의학회 2006 대한후두음성언어의학회지 Vol.17 No.1

Purpose: Evaluation of vocal cord vibration is very important in cases of voice disorders. There are several equipments for examining the vocal fold vibration such as laryngeal stroboscope, ultra high-speed digital imaging system, and videokymograph. Among these, laryngeal stroboscope is the most popular equipment because of easy to examine the laryngeal pathology. However, current laryngo-stroboscopes are too bulky to move and relatively expensive. The purpose of this research is to develope a portable laryngeal stroboscope of equivalent performance with the current equipments. Methods and Materials: Recently developed high luminescent white LEDs(light emitting diodes) are placed at the head of the endoscope as light sources for the CCD image sensor which is also placed at the head with imaging lens. This arrangement eliminates the bulky light source like expensive halogen or xenon lamps as well as the optical light guiding cables. The LEDs are controlled to flash in phase with the voice frequency of the examinee. The CCD captures these strobo images and converts them into video signals for examinations. Results: There was no functional differences between preexisting stroboscope and the newly developed stroboscope of this study. LED light sources and microprocessor based control circuits of the stroboscope enabled the development of flicker-less, hand-held, portable and battery-operating stroboscope. Conclusion: The developed stroboscope is cost-effective, small-sized, easy to use and very easy desirable to bring and to use in any place.

세포재순환 연속반응기의 적응제어

이재우,유영제 ( Jae Woo Lee,Young Je Yoo ) 한국화학공학회 1992 춘계학술발표논문집 Vol.- No.-

CNN 추론 연산 가속기를 위한 곱셈기 최적화 설계

이재우,이재성,Lee, Jae-Woo,Lee, Jaesung 한국정보통신학회 2021 한국정보통신학회논문지 Vol.25 No.10

Recently, FPGA-based AI processors are being studied actively. Deep convolutional neural networks (CNN) are basic computational structures performed by AI processors and require a very large amount of multiplication. Considering that the multiplication coefficients used in CNN inference operation are all constants and that an FPGA is easy to design a multiplier tailored to a specific coefficient, this paper proposes a methodology to optimize the multiplier. The method utilizes 2's complement and distributive law to minimize the number of bits with a value of 1 in a multiplication coefficient, and thereby reduces the number of required stacked adders. As a result of applying this method to the actual example of implementing CNN in FPGA, the logic usage is reduced by up to 30.2% and the propagation delay is also reduced by up to 22%. Even when implemented with an ASIC chip, the hardware area is reduced by up to 35% and the delay is reduced by up to 19.2%.

Herpes simplex virus-thymidine kinase 유전자가 전이된 종양 세포에서 Gancyclovir와 방사선 조사에 의한 항 종양 효과

이재우,오승택,안창혁,임근우,조현일,김금용,김태규,Lee, Jae Woo,Oh, Seong Taek,Ahn, Chan Hyuk,Lim, Kun Woo,Cho, Hyun-Il,Kim, Gum Ryong,Kim, Tai-Gyu 대한면역학회 2001 Immune Network Vol.1 No.1

Background: Many types of cancer become resistant to current chemotherapeutic and radiotherapeutic intervention. To overcome this situation application of gene therapy by the introduction of suicide genes followed by their prodrugs may be promising. A viral enzyme, Herpes simplex thymidine kinase (HSV-tk), which converts ganciclovir from an inactive prodrug to a cytotoxic agent by phosphorylation, are being actively investigated for use in gene therapy for cancer. The purpose of this study was to determine whether combining prodrug-activating gene therapy and irradiation might result in enhanced antitumor effects. Methods: The HSV-tk gene was cloned into the retroviral vector, pLXSN and established the clones producing retroviruses carrying the HSV-tk gene. The carcinoma cell line, HCT116 and Huh-7 were transduced with high-titer recombinant retroviruses. These cell lines were treated with ganciclovir before or after irradiation for the defining combinational effect of suicide gene therapy and radiotherapy. Results: The titers of cloned PA3 17 amphotropic retroviruses ranged from 4 to 6 X $10^6CFU/ml4$. After selectional periods, the expression of HSV-tk was confirmed by reverse-transcriptase polymerase chain reaction (RT-PCR). The growth of cells expressing HSV-tk was inhibited as increase of GCV dose after 48 hr and the growth inhibitory effect of GCV was much higher after 72 hr. When the cells transduced with HSV-tk gene were exposed to radiation, the growth inhibitory effect of GCV was significantly increased, as compared with non-transduced parental cells. Conclusions: The results suggest that the addition of HSV-tk gene therapy to standard radiation therapy may improve the effectiveness of treatment for solid tumors.

상표소와 상심자가 난소적출로 유발된 흰쥐의 골다공증 치료효과에 미치는 영향

이재우,서부일,박지하,노성수,김용현,김미려,Lee, Jae-Woo,Seo, Bu-Il,Park, Ji-Ha,Roh, Seong-Soo,Kim, Yong-Hyun,Kim, Mi-Ryeo 대한본초학회 2009 대한본초학회지 Vol.24 No.1

본 연구는 상표소와 상심자가 난소적출로 유발된 흰쥐의 골다공증 치료효과에 미치는 영향에 관한 것으로서 주요 내용은 다음과 같다. 본 연구에서는 상표소와 상심자 물 추출물을 난소를 절제한 흰쥐에 투여하여 대퇴골, 비골경골의 골밀도, 혈청 중 오스테오칼신 함량, 알칼리성 인산가수분해효소 활성도, 칼슘 함량, 인 함량, 소변 중 무기성분의 변화, deoxypyridinoline 함량 등과 뼈의 함량, 인 함량, ash 무게에 미치는 영향을 살펴보았다. 본 실험 결과 상표소와 상심자 물 추출물은 폐경기 이후 골다공증에 대한 치료에 효과적이라고 판단된다는 내용이다.

용존산소가 SBR 공정에서 질소와 인의 제거에 미치는 영향

이재우,정태학 ( Jae Woo Lee,Tai Hak Chung ) 한국물환경학회 1997 한국물환경학회지 Vol.13 No.1

Effect of Dissolved Oxygen(DO) on the treatment efficiency of wastewater in the Sequencing Batch Reactor(SBR) process was investigated. The peak DO level was maintained below 1㎎O₂/L or above 6㎎O₂/L during the oxic period. Despite low D0, the organic removal efficiency was higher than 95%, but the nitrification was considerably inhibited. This resulted in significant increase in the phosphorus release and improvement of phosphorus removal efficiency. Biological phosphorus removal was accelerated by high organic loading. Large amounts of phosphorus were released during the idle period although there was no influent. When nitrate was used instead of ammonia as a nitrogen source, phosphorus release decreased because of phosphorus uptake at the later part of anoxic period. Polyhydroxyalkanoates(PHA) stored in the cell responded well in accordance with organic availability and phosphorus transport. It is possible to achieve high removal of organic and phosphorus by operation of the reactor at low DO.

세라믹 및 초경합금 성형체의 피절삭성

이재우,Lee, Jae-Woo 대한기계학회 1997 大韓機械學會論文集A Vol.21 No.9

Machining pressed compacts of ceramic and WC-Co materials can be the most cost effective way of forming the bodies prior to sintering when the required number of pieces is small. In this study, in order to clarify the machinability for turning, the $Si_3N_4$ and the WC-Co green compacts unsintered were machined under different cutting conditions with various tools. Absorbing chips by vacuum hose decreases tool wear. The tool wear becomes larger in the order of the ceramic, CBN and cemented carbide tools in machining the $Si_3N_4$ green compacts. In machining the WC-Co green compacts, the tool wear becomes larger in the order of the ceramic, cemented carbide and CBN tools. The land of cutting edge does not affect tool wear. When machining with cemented carbide tool, the tool wear i equal cutting length is nearly identical in spite of the increase of cutting spee, and the roughness of machined surface was the best in the cutting speed of 90 m/min. The tool wear decreases with the increase of rake angle and relief angle and with the decrease of nose radius. The machined surfaces become worse with the increase of feed rate and depth of cut, and with the decrease of rake angle and relief angle. The tool wear is not affected by the feed and depth of cut.

전기적 응용을 위한 바나듐옥사이드 나노선/폴리비닐 알코올 복합체 제작

이재우,이강호,김규태,Lee, Jae-Woo,Lee, Kang-Ho,Kim, Gyu-Tae 한국전기전자학회 2009 전기전자학회논문지 Vol.13 No.2

$V_2O_5$ nanowire / polyvinyl alcohol (PVA) polymer composite fibers were fabricated by a new simple method. The reaction of PVA and acetone facilitates the formation of the polymer membrane which can be used to make the fiber. Composite fiber is percolative in the conductance because of the low percolation threshold in $V_2O_5$ nanowire networks. The fiber composite can be applied to the electromagnetic shielding originating from the conductive nature.

자동차 타이어용 고무 압출물의 점탄성 특성에 따른 압출 다이의 응답성 분석

이재우(Jae Woo Lee),정창복(Chang Bok Chung) 한국고분자학회 1997 폴리머 Vol.21 No.4