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백지현,박은영,정윤숙,홍재원,채윤태,진성준,최희경,신소연,한상훈,진범식,김창오,최준용,송영구,조남훈,김준명 대한감염학회 2009 감염과 화학요법 Vol.41 No.4
Coccidioidomycosis is a fungal infection that results from inhaling the airborne arthroconidia of the Coccidioides species. It is an endemic disease in the southwest part of North America and rarely diagnosed in Korea. As tourism to endemic areas and the number of immunocompromised patients have been increasing, the incidence of this infection has increased in non-endemic areas. Treatment is usually successful with antifungal agents; however, recurrence is common. It is difficult to decide when to discontinue the antifungal treatment especially in non-endemic areas where doctors are not familiar with the disease. We report a case of recurrent coccidioidomycosis manifesting as osteomyelitis after the treatment of the patient for disseminated coccidioidal infection. The complement fixation test was a useful tool for the assessment of patient response and to evaluate suspected recurrence.
중소규모 사업장 근로자의 직무스트레스로 인한 결근, 조퇴 현황과 한국형직무스트레스 하부요인과의 관련성
김정훈,박신구,김동현,김환철,임종한,이의철,이동훈,이지영 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.2
목적: 중소규모 사업장 근로자들의 직무 스트레스로 인한 결근, 조퇴의 현황과 한국형 직무 스트레스 하부 요인과의 관련성을 알아보고자 하였다. 방법: 중소규모 사업장 83곳 근로자들에 대해 한국형 직무스트레스요인 평가도구-단축형(KOSS-SF)과 사회 일반적 특성, 직업적 특정 및 직무스트레스로 인한 결근이나 조퇴 경험여부 등을 묻는 구조화된 자가 기입식 설문을 실시하였고, 응답한 4,350명에 대해 최종 분석을 시행하였다. 직무스트레스로 인한 결근, 조퇴와 한국형 직무스트레스 하부 요인들과의 관련성을 확인하기 위하여 로지스틱 회귀분석을 시행 하였다. 결과: 직무 스트레스로 인한 결근, 조퇴를 한 근로자는 남자에서 7%(196명), 여자에서 8%(113명) 로 조사되었고 한국형 직무 스트레스 하부요인과의 관련성에서는 남, 여 모두 직무요구, 관계갈등, 조직체계, 보상부적절, 직장문화 영역의 스트레스가 높은 군에서 통계적으로 의미있게 직무스트레스로 인한 결근, 조퇴율이 증가하였다. 결론: 중소규모 사업장 근로자들의 직무 스트레스로 인한 결근, 조퇴와 한국형 직무 스트레스 하부요인과의 관련성은 남자에서는 조직체계 영역이 가장 높았고, 여자는 직장문화 영역에서 가장 높은 관련성을 보였다. Objective: The aim of this study was to examine the actual conditions of absence and early leave due to job stress of 4,350 workers in 83 small and medium scale industries, and its relationship to job stress factors using Korean Occupational Stress Scale-Short Form (KOSS-SF). Methods: A structured self-reported questionnaire was used to assess each respondent's Sociodemographics, job stress, experience of absence and early leave due to job stress. Seven KOSS-SF domains of job stress were used. We estimated the relation of absence and early leave due to job stress and job stress factors using logistic regression analyses. Results: Absence or early leave due to job stress occurred in 7% of male workers and 8% of female workers. Multiple regression analysis revealed a significantly positive association job stress-related absence/early leave and job demand, interpersonal conflict, organizational system, lack of rewards and occupational climate. Conclusions: Absence and early leave due to job stress is significantly attributed to organizational System and lack of reward for men, and occupational climate and organizational system for women.
노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성
유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6
Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.
Attraction and repellent activity of essential oils against Lycorma delicatula
Han-Goo Ji,Ji-Hyeon Park,Bong-Ki Son,Hwa-Jeong Yeom,Sang-Rae Moon,Changmann Yoon,Chul-Sa Kim,Gil-Hah Kim 한국응용곤충학회 2009 한국응용곤충학회 학술대회논문집 Vol.2009 No.10
Using thirty-one essential oils with different manufactured T-tube olfactometers, attraction and repellent efficacy were proved against ggot-mae-mi, Lycorma delicatula. Among tested essential oils, spearmint was selected to have attraction efficacy (94.1%; P<0.001). Spearmint was also showed attraction efficacy in 10 and 2.5 ul, but did not showed in 1 ul. GC analyzed chemical constituents of spearmint were tested with different concentations (10, 5, 2.5, 1 ul). Carvone were showed activity in 10 and 5 ul, but limonene did not showed the activity. When mixing two compounds were showed activity in 10, 5, 2.5 ul as 78.8, 73.5, and 69.7%, respectively. Lavender was selected to have repellent efficacy (86.7%; P<0.001). Lavender was also showed repellency in 10 and 2.5 ul, but did not showed in 1ul. GC analyzed chemical constituents of lavender were tested with different concentrations, results have the activity linalool and terpinen-4-ol in 10 and 5 ul, but linalyl acetate and caryophyllene oxide did not have the activity. Spearmint and lavender showing attraction and repellency, respectively, were keep in lure during 24 hr for penetration with different concentration(30, 20, 10 ul), and attached to the center of Fly catcher, fly sticky trap. The trap was set in the field that founded frequently the L. delicatula. The number of L. delicatula caught in the traps were counted after 5, 10, and 15 days. In attraction efficacy of 20 ul concentration wㄷre high attracted the insect(P<0.001). 30 ul concentration were also have the high attraction (P<0.01). We are now tested the control efficacy in grapevine orchard using these materials.
뉴캣슬병 바이러스 검출 및 병원성 감별을 위한 Duplex RT-PCR법 개발
김지예(Ji-Ye Kim),이현정(Hyun-Jeong Lee),장일(Il Jang),이희수(Hee-Soo Lee),윤성준(Seung-Jun Yoon),박지성(Ji-Sung Park),설재구(Jae-Goo Seol),김승환(Seung-Han Kim),홍지무(Ji-Mu Hong),Zillian Wang,Hualei Liu,최강석(Kang-Seuk Choi) 한국가금학회 2017 韓國家禽學會誌 Vol.44 No.2
본 연구에서 NDV의 L유전자와 F유전자를 표적 부위로 각각 제작한 primer 세트를 사용함으로써 하나의 PCR 튜브에서 NDV 검출(386 bp의 증폭 크기)과 함께 병원성 NDV (229 bp의 증폭 크기)를 동시에 감별 증폭할 수 있는 dRTPCR 검사법을 개발하였다. 개발된 dRT-PCR검사법은 NDV를 특이적으로 검출하고, 병원성을 감별하였다. 특히 국내 병성감정 실시기관에서 적용 중인 기존의 RT-PCR 상용키트에서는 검출하지 못하는 class I NDV과 PPMV(class II 유전형 VI형)을 NDV를 검출함과 동시에 병원성 NDV도 감별가능하였다. 개발된 dRT-PCR 검사법의 검출 민감도는 약 103.0EID50/0.1 mL로 평가되었다. 또한 ND발생국의 야외 시료에 적용했을 때, NDV 공통항원 검출율은 94.4%였으며, 병원성 NDV 검출율은 100%이었다. 그러므로 본 연구에서 개발한 dRT-PCR 검사법은 의심축 사례에서 ND를 신속 정확하게 진단하는 데 유용할 진단 방법을 제공할 수 있을 것으로 판단된다. A duplex RT-PCR (dRT-PCR) assay was developed for the simultaneous detection and discrimination of nonvirulent and virulent Newcastle disease virus (NDV) in a single PCR tube. Primers targeting the large polymerase protein (L) gene and the fusion protein (F) gene of NDV were designed to detect all NDVs (by common type PCR primers) and virulent NDVs (by pathotype PCR primers), respectively and evaluated experimentally with reference NDV strains and other poultry viral pathogens. PCR products of the expected size of 386 bp were amplified from all NDV samples whereas PCR products of the expected size of 229 bp were amplified from virulent NDV samples alone. Cross reaction was not observed with other avian viral pathogens. The detection limit of NDV by the dRT-PCR was estimated to be 103 50% egg infectious dose/0.1 mL. In the dRT-PCR using field isolates of NDV, the pathotype PCR primers detected specifically all of virulent field isolates of NDV from Malaysia, Pakistan and China whereas common type PCR primers detected 94.4% (51/54) of field isolates of NDV from China. Three Chinese NDV isolates with false negative result were non-virulent viruses. Our results indicate that the dRT-PCR might provide a rapid and simple tool for rapid simultaneous detection and discrimination of non-virulent and virulent NDVs. Therefore the developed dRT-PCR assay provides a powerful novel means for the rapid diagnosis of Newcastle disease.
알칼리 활성 모르타르의 감수제 종류 및 첨가율 변화에 따른 감수율 및 강도발현 특성
장지한(Chang, Ji-Han),한천구(Han, Cheon-Goo) 대한건축학회 2015 大韓建築學會論文集 : 構造系 Vol.31 No.5
It is well known that the water reducing rate of concrete are affected by the kind of organic admixtures. Organic admixture can improve the properties of concrete. Sulfonated Naphthalene - Formaldehyde(Pn) superplasticizer and Poly - carboxylate(Pc) are used representatively, but most study deal with alkali - activator and amorphous binder. In this study, we investigated the influence of mixture ratio of superplasticizer"s type on the water reducing rate and compressive strength. In view of the results, we found that the admixture ratio of superplasticizer"s type results to be significant factors. It is represent that water reducing rate of Pn and Li is about 16 % in the dosage of 2 %, but air content was severly increased in the case of Li. Also the compressive strength was increased with superplasticizer"s ratio is until 0.5 %.