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      • KCI등재

        지역사회에서 형성된 사회적 지지와 근로자의 사회심리적 스트레스간의 관련성

        임화영,김형수,최영환,장성훈,이건세,정최경희,오원기,최재욱,정춘화 대한산업의학회 2006 대한직업환경의학회지 Vol.18 No.4

        Objective: This study was performed to examine the relationship between community-based social support and psychosocial distress in workers. Methods: The study subjects were 596 workers recruited from 11 companies in Chungju city. A structured questionnaire was used to assess sociodemographics, health-related behaviors, job characteristics, job stress, work-based social support, community-based social support and level of psychosocial distress. Results: Hierarchical multiple regression analysis showed that workers with no chronic disease, exercise and sufficient sleep had a higher score of psychosocial distress than those with chronic disease, no exercise, and not enough sleep. Coworker's work-based social support and community-based social support were negatively associated with psychosocial distress. The R square value of total independent variables on psychosocial distress was 0.409, and that of community-based social support on psychosocial distress was 0.052. Conclusion: This study showed that community-based social support served as a protective factor against psychosocial distress in some workers. We recommend the establishment of a worksite stress reduction program in occupational level as well as community-based social support.

      • 비만증 환자에서 한약제에 의한 체중 감소효과

        Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

      • Hepatocellular Carcinoma in the Elderly: Clinical Characteristics, Outcomes and Treatment Efficacy, Safety in Older than 75 Years

        ( Ji Ho Seo ),( Sunmin Kim ),( Eunae Cho ),( Chung Hwan Jun ),( Sun Young Park ),( Sung Bum Cho ),( Chang Hwan Park ),( Hyun Soo Kim ),( Sung Kyu Choi ),( Jong Sun Rew ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: The number of elderly patients diagnosed with hepatocellular carcinoma (HCC) has been increasing because the increase in the longevity of the general population. But there is no proper management based on age stratification in elderly patients. We compared clinical characteristics, outcomes and treatment efficacy, safety between oldest-old (aged more than 85 years), middle-old (aged between 80 and 85 years) and young-old (aged between 75 and 80 years) patients with HCC. Methods: We conducted a retrospective cohort study, from January 2010 to December 2016, at Chonnam National University Hospital. A total of 550 elderly patients whose data included demographics, co-morbidity, etiology of liver disease, presence of cirrhosis, staging of HCC, treatment modality and treatment related adverse event were evaluated retrospectively. Also overall survival was assessed in enrolled patient. Results: Fifty one patients (oldest-old; median 87 years old), 153 patients (middle-old; median 82 years old) and 346 patients (young-old; median 77 years old) were diagnosed with HCC. Both oldest- and middle-old patients, compared to young-old patients had significantly lower rate of alcohol-related disease (13.7% vs 20.9% vs 34.1%, P = 0.001). There were no significant difference in underlying sex, body mass index, presence of co-morbidity, hepatitis C-related disease and stage of HCC. The Child-Pugh class (CPT class A 88.9% vs 84.1% vs 83.6%, CPT class B 11.1% vs 15.9% vs 15.0% and CPT class C 0.0% vs 0.0% vs 1.3%, respectively, P = 0.912) and Model for End Stage Liver Disease score (mean MELD score 7.22±3.34 vs 5.88±3.01 vs 5.77±3.14, P = 0.166) were no significant difference between the patients with active treatment. The modified UICC staging (stage I 5.6% vs 17.1% vs 18.6%, stage II 55.6% vs 46.3% vs 47.3%, Stage III 22.2% vs 24.4% vs 24.8%, Stage IV-A 11.1% vs 6.1% vs 4.9% and Stage IV-B 5.6% vs 6.1% vs 4.4%, respectively, P = 0.826) and Barcelona Clinic Liver Cancer staging (stage 0 5.6% vs 9.8% vs 9.3%, stage A 16.7% vs 17.1% vs 22.1%, stage B 27.8% vs 29.3% vs 24.8%, stage C 50.0% vs 43.9% vs 41.2% and stage D 0.0% vs 0.0% vs 2.7%, respectively, P = 0.878) were no significant difference between the patients with active treatment. Furthermore, there were no difference between the age groups in treatment modality (Surgical resection 0.0% vs 3.3% vs 5.2%, P = 0.166; Radiofrequency ablation 2.0% vs 8.5% vs 11.0%, P=0.113; Transcatheter arterial chemoembolization 21.6% vs 34.6% vs 41.6%, P=0.014; Best supportive care 62.7% vs 40.5% vs 29.2%, P < 0.001), adverse event related treatment (P = 0.731) and disease-free survival days (329 .3±309.1 days vs 271.7 ± 414.2 days vs 357.2 ± 511.6 days, P = 0.336). Multivariate analysis showed that age, performance status, CTP class, MELD score, modified UICC staging, presence of portal vein thrombosis and ruptured HCC are risk factors for mortality. Conclusions: Clinician should make an active treatment in elderly patients with HCC not a age but performance status, liver function and disease status of cancer.

      • SCOPUSKCI등재

        고령자 (고령자) 십이지장 궤양 (궤양)

        정준모(Joon Mo Chung),정극수(Keuk Soo Chung),최용환(Yong Hwan Choi),김인호(In Ho Kim),김효석(Hyo Seuk Kim),김영재(Young Jae Kim) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.1

        N/A Clinical studies on patients with duodenal ulcer who visited endoscopy room of Kyungpook National University Hospital since 1976 were performed. Among these patients, we compared the number of patients with gastric or duodenal ulcer yearly, and some aspects of difference between 57 cases of old age(above 60 years) and 129 cases of young age(under 30 years) patients with duodenal ulcer. The results obtained were as follows. 1) In examined cases, number of patients with duodenal ulcer was progressively increased year by year and number of gastric ulcer was more prevalent than that of duodenal ulcer unti11979 when the ratio of gastric and duodenal ulcer became nearly same, and thereafter duodenal ulcer cases were begun more predominant about 2 times that of gastric ulcer in 1981 2) Comparing the sex distribution of old and young age group, male was predominant about 12 times of female cases in young age group and about 2.5 times in old. 3) Overall complications including bleeding, perforation, obstruction and others were seen in 63. 2% of old age group and in 48.1% of young. 4) In 8 weeks follow up cases that was possible although it was least in number, 8 cases were improved or healed in old age group but 5 cases out of 18 cases in young revealed no improvement by ordinary regimen.

      • 2자유도를 갖는 3차원 운동 시뮬레이터 연구

        최명환,김영진 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.A

        In this work, we have developed a 2 degrees of freedom(DOF) motion simulator that can generate the sensation of motion in a 6 DOF space. The motion base has the DOF of roll and pitch, and the purpose of the motion base is to create the sensation of riding a vehicle in a 3D space by controlling the motion base. The dynamics of the mechanism was analysed and the optimal design of the motion base mechanism has been reached. The prototype motion base mechanism was developed and tested. The multi-axis motion controller(MMC) was used to control the two AC servo meters that drive the roll and pitch motion.

      • FCL(5-FU, Carboplatin, Leucovorin) 항암 화학요법에서 Gm-CSF의 효과

        최지영,김현수,김종숙,박상준,윤환중,조덕연,남상륜,김삼용 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

        Background: One of the major side effects of cancer chemotherapy is myelosuppression. Neutropenia and/or thrombocytopenia are dose-limiting factors in chemotherapy. Colony-stimulating factor induces proliferation and functional maturation of hematopoietic progenitor cells. GM-CSF is primarily active on progenitor cells of granulocytic and monocytic lineage. Methods: Fifteen patients with histologically proven malignancy diagnosed at Chungnam National University Hospital from January 1993 to August 1995 were included in this study. We could evaluate the clinical efficacy of GM-CSF in 13 patients undergoing FCL(5-FU, Carboplatin and Leucovorin) chemotherapy; the first cycles involved no GM-CSF while the second cycles involved GM-CSF on day 6 through 15 of chemotherapy. Results: 1) The subjects were fifteen patients in all, there were five patients with head and neck cancer, which was the most common types of maligancy. There were four patients with colon cancer, two patients with stomach cancer, and one patient with breast cancer, gallbladder cancer, cervix cancer and cholangiocarcinoma respectively, two patients, who did not complete two cycles of chemotherapy were excluded. 2) Age distribution was from 38 years to 78 years with a median age of 57. 3) In FCL chemotherapy cycles with GM-CSF, the duration of neutropenia(<500/μL) was 0.5±0.3 day, while FCL chemotherapy cycles without GM-CSF, it was 2.9±0.7 day(P=0.008). 3) There was no significant difference in platelet count between the two chemotherapy cycles(P=0.133). 4) Febrile duration without GM-CSF was 4.9±2.1 day, but with GM-CSF the duration was 1.3±0.7 day, which was significantly different(P=0.003). The duration of antibiotics use with GM-CSF was 1.7±1.2 day and without GM-CSF was 6.8±3.2 day, also significantly different(P=0.002). But hospital stay between the two cycles were not significantly different(P=0.064). Conclusion: GM-CSF was effective in preventing or restoring bone marrow depression after FCL chemotherapy.

      • KCI등재

        작업관련 상지의 근골격계 질환 선별 및 감시를 위한 미국 NIOSH-style 설문지와 Nordic-style 설문지의 타당도 비교

        최원준,성낙정,강영중,한상환 大韓産業醫學會 2008 대한직업환경의학회지 Vol.20 No.3

        목적: 작업관련 근골격계 질환의 선별검사에 사용되는 두 종류의 증상설문지(NIOSH 스타일 설문지,노르딕 스타일 설문지)의 결과를 신체검사 결과와 비교하여 타당도를 평가하고,활용방안에 대하여 검토하고자 수행되었다. 방법: 인천에 위치한 3개의 제조업 사업장 근로자 208명을 대상으로 NIOSH 스타일 설문지와 노르딕 스타일 설문지를 작성하도록 하고,신체검사를 시행하였다. 신체 검사 소견과 과거병력을 바탕으로 한 환례정의를 최적기준으로 하여 두 설문지의 민감도,특이도,양성예측도,음성예측도,일치도를 구하여 타당도를 조사하였다. 결과: NIOSH 스타일 설문지는 민감도 59.5%, 특이도 68.0%, 양성예측도 68.0%, 음성예측도는 59.5%로 조사되었다. 카파계수(Kappa coefficient)로 나타낸 일치도는 0.27(95% confidence interval 〔CI〕=0.14∼0.40)이었다. 노르딕 스타일 설문지는 민감도 73.9%, 특이도 68.0%,양성예측도 72.6%,음성예측도 69.5%로 조사되었다. 카파계수로 나타낸 일치도는 0.42(95% CI=O.30∼0.54)이었다. NIOSH 스타일 설문지와 노르딕 스타일 설문지의 일치도는 카파계수 0.43(95% CI= 0.31∼O.55)로 나타났다. 증상강도의 합계점수가 2점 이상인 경우를 기준으로 했을 때,노르딕 스타일 설문지의 민감도는 72.1%,특이도는 70.1%이었다. 결론: 두 설문지 모두 적절한 타당도를 가지고 있는 것으로 평가되었다. NIOSH 스타일 설문지는 증상의 빈도,지속기간,강도를 조사할 수 있고 이에 따라 다양한 양성기준을 설정할 수 있다. 노르딕 스타일 설문지는 민감도가 높은 편이고,증상의 강도를 설문항목에 포함시킬 경우 양성기준을 다양화하기 쉽다는 점과 문항이 간단하고 작성하기 쉽다는 점을 장점으로 들 수 있다. 조사 목적과 작업장의 특성에 따라 두 설문지를 적절하게 활용할 수 있을 것으로 기대된다. Objectives: The study aimed to compare the validity of two questionnaires (NIOSH- and Nordic-style) which are used for the screening and surveillance of neck and upper extremity work-related musculoskeletal disorders. To evaluate the validity, clinical examination was used as the reference. Methods: Two types of questionnaire were filled out by 208 workers from three different plants in Incheon, Korea. Workers underwent clinical examination by three occupational physicians. The presence of a symptom or sign in at least one body region was regarded as positive in both results of questionnaire and case definition using clinical examination. Validity was evaluated by sensitivity, specificity, positive predictive value, negative predictive value and agreement (Kappa coefficient). For the Nordic-style questionnaire, the sum of the symptom scores was used to yield the ROC curve. Results: The results of the NIOSH-style questionnaire were sensitivity 59.5%, specificity 68.0%, positive predictive value 68.0%, negative predictive value 59.5%, and Kappa coefficient 0.27(95% confidence interval [CI]=0.14∼0.40). The results of the Nordic-style questionnaire were sensitivity 73.9%, specificity 68.0%, positive predictive value 72.6%, negative predictive value 69.5%, and Kappa coefficient 0.42 (95% CI=0.30∼0.54). For the Nordic-style questionnaire, sensitivity was 72.1 % and specificity was 70.1 % based on the sum of the symptom scores≥2. Conclusions: Both questionnaires demonstrated appropriate validity for the screening and surveillance of work-related musculoskeletal disorders. The selection of questionnaire may depend on the purpose of investigation and characteristics of the work place.

      • 토안에서 금판 삽입술의 효과

        최시환,박영규,박우찬 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

        Lagophthalmos can result in serious keratopathy because of corneal exposure and inadequate lacrimation. Four patients underwent gold plate insertion to rehabilitate paralysis of the eyelid caused by facial nerve palsy. Gold plate insertion resulted in exellent eyelid closure, protection, and cosmesis. There were no infections or extrusions. Lagophthalmos and exposure keratitis were resolved or were significantly improved in these patients. In selected patients this technique reestablishes a voluntary blink and provides corneal protection without the limitation of tarsorrhaphy. Gold plate insertion has become the procedure of choice for eyelid rehabilitation.

      • 지체장애인 편의시설의 현황 및 개선방안에 관한 연구 : 대구광역시 사회복지관을 중심으로 Focusing of The Welfare Facilities in Daegu

        최영오,박승환,최무혁 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(계획계)

        This study is to search for appearance of facilities based on facility improvement and then analyzes degree of satisfaction of user and level of facilities by comparing. This study is focused of welfare facilities in Daegu. Conclusions as follow : 1 Satisfaction of the facility is different whether welfare facilities were founded before establishment by law of facility improvement or not. 2 Most welfare facilities is weak an elevator equipment. So the right to access for the handicapped act has been limiting so much. 3 Expansion of parking areas for disabled person are urgent.

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