수면이 균형조절과 시각적 자극 반응시간에 미치는 영향

박수경,박정아,박강희,김주헌,홍용근,Park, Sookyoung,Park, Jung-A,Park, Kanghui,Kim, Joo-Heon,Hong, Yonggeun 대한수면의학회 2016 수면·정신생리 Vol.23 No.2

목 적 : 수면은 신체의 기능을 회복시키고 항상성을 유지시키는 인체의 필수적인 생리작용으로, 수면의 질 저하는 전반적인 건강문제를 야기 시키는 것으로 보고되고 있다. 따라서 본 연구에서는 수면과 균형조절능력의 관계에 대해 규명하기 위하여, 수면이 균형조절과 시각적 반응시간에 미치는 영향에 대해 알아보고자 하였다. 방 법 : 본 연구에 참여하기를 서면 동의한 건강한 20대 남녀 58명을 대상으로 PSQI를 이용하여 수면의 질을 평가한 다음, PSQI 점수에 따라 대상자를 A군(PSQI <5)과 B군($PSQI{\geq}5$)으로 분류하였다. 이후 대상자들의 체성분과 신체특성, 균형조절, 시각적 반응시간 및 오류횟수를 각각 측정하였다. 결 과 : 수면의 질이 양호한 A군에 비해 수면의 질이 낮은 B군에서 아침기상 시 졸린 정도가 유의하게 높은 것으로 나타났다. 수면이 체성분에 미치는 영향에 대해 알아보기 위해 두 실험군의 신체조성을 비교한 결과, 수면의 질이 낮은 여자 대상자들의 체지방량과 체지방률이 유의하게 낮은 것으로 확인되었다. 또한 수면상태에 따른 균형을 비교한 결과, 유의한 차이가 나타나지 않았지만, 시각적 반응시간에서는 유의한 증가가 확인되었다. 특히 수면의 질이 낮은 B군에서 반응시간은 선형적으로 유의하게 증가하였으며, 오차횟수 역시 증가하는 것으로 나타났다. 결 론 : 수면의 질 저하는 반응속도를 지연시키고, 반응의 정확도를 감소시키는 것으로 나타났는데, 이러한 선택적 주의력의 저하는 균형조절에 영향을 끼칠 수 있고, 이로 인해 예상하지 못한 순간에 낙상 등의 손상을 입을 위험이 증가할 수 있다. Objectives: To find evidence that sleep is necessary for normal brain function, thus indicating that declines in both sleep quality and quantity are related to worse performance of many daily tasks and deteriorated physical functions. The present study investigates the relationships of balance control and reaction time with sleep quality. Methods: 58 healthy (male 20, female 38) volunteers with informed consent participated in this study. The Self-reported Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality and relevant factors, and the subjects were divided into groups A (PSQI < 5) and B ($PSQI{\geq}5$) based on this index. Static balance control and reaction time to visual stimuli were conducted to assess their relationship with sleep quality. Results: Group B exhibited excessive daytime sleepiness significantly more often compared to group A. Static balance control did not markedly change relative to sleep quality, but reaction time and error to visual stimuli were significantly increased in group B compared to group A. Conclusion: These findings indicate that a decline in sleep quality can result in delayed reactions, as well as decreased accuracy of these reactions. They also suggest that low sleep quality may be associated with changes in physical functions, including balance control through reduced selective attention.

경동맥 초음파를 이용한 뇌경색 환자의 내경동맥 협착도와 습담변증(濕痰辨證)의 관련성 연구

박수경,곽승혁,우수경,이은찬,박주영,정우상,문상관,조기호,박성욱,고창남,Park, Su-kyung,Kwak, Seung-hyuk,Woo, Su-kyung,Lee, Eun-chan,Park, Joo-young,Jung, Woo-sang,Moon, Sang-kwan,Cho, Ki-ho,Park, Sung-wook,Ko, Chang-nam 대한중풍순환신경학회 2011 대한중풍.순환신경학회지 Vol.12 No.1

Objectives : This study was aimed to clarify the relationship between the dampness-phlegm diagnosis and internal carotid artery stenosis by measuring carotid artery sonography in cerebral infarction patients. Methods : One hundred eighty subjects were recruited from the patients admitted to the Department of Internal Medicine at Kyunghee university oriental medical center from September 2008 to July 2010. We assessed one hundred eighty patients' carotid artery sonography data and diagnosed dampness-phlegm by oriental medical diagnosis. then, analyzed their characteristics, risk factor, lifestyle, metabolic syndrome, body mass index, Waist/Hip ratio(W/H ratio) and dampness-phlegm diagnosis. Results : On the demographic variables of the patients, age, smoking, W/H ratio and dampness-phlegm group were significantly higher in severe internal carotid artery(ICA) stenosis group than in the control group. According to the significant difference in dampness-phlegm group, we analyzed dampness-phlegm related index for pattern identifications by ICA stenosis. As a result, sputum, bowel sound, chest discomfort, slippery pulse were significantly higher in the severe ICA stenosis group than in the control group. In multivariate analysis, dampness-phlegm group showed close relationship with severe ICA stenosis group. Conclusion : According to the analysis, significance between dampness-phlegm diagnosed patients group and severe ICA stenosis were clarified. These results can be utilized in the future as a basis material.

Remote Afterloading High Dose Rate Brachytherapy AMC EXPERIANCES

박수경,장혜숙,최은경,이병용,김재성,Park, Su-Gyeong,Chang, Hye-Sook,Choi, Eun-Kyong,Yi, Byong-Yong,Kim, Jae-Sung The Korean Society for Radiation Oncology 1992 Radiation Oncology Journal Vol.10 No.2

원격조정 고선량 근접치료는 새로운 각광받는 테크놀로지이다. 이에, 저자들은 3년간의 서울중앙병원의 590횟수, 116 환자를 대상으로 고선량 근접치료의 그 시술과 임상적 결과를 평가해 보고자 한다 자궁경부암 58 환자와 비인두강암 26 환자의 관내 방사선치료 471 횟수, 식도암 12 환자, 내 기관지암 11 환자, 클라스킨 종양 1 환자의 관내 방사선치료 79 횟수와 유방암 4 환자, 육종 1 환자, 요도암 1 환자의 조직내 방사선치료 40 횟수가 1989년 9월에서 1992년 8월 사이에 시행되어졌다. 추적 관찰 기간은 1 개월에서 35개월이었고, 그 중간 기간은 7개월이었다. 조직내 방사선치료를 제외한 모든 시술은 국소 마취로 시행하였고, 모든 환자에서 급성 합병증은 생기지 않았다. 또한, 6 환자를 제외하고는 모두 계획 선량대로 치료를 마칠 수가 있었다. 자궁경부암 58 환자에서, 비인두강암 26 환자 중 20 환자에서 완전 관해가 일어났으며, 증상 완화 목적으로 치료한 15 환자에서 $80{\%}$의 환자에서 소기의 목적을 이룰 수 있었다. 이 논문에서 원격조정 고선량 근접치료의 자세한 시술과 그에 따른 결과를 설명할 것이다. 이 치료의 생물학적인 효과와 적당한 선량/선량 횟수/분할치료를 평가하기 위해, 우리는 더욱 긴 추적 관찰을 시행하여야 하며, 이 새로운 근접치료 시술이 저선량 근접치로 시술보다 효과적이고 외래 환자로 통근 치료가 가능하며, 안전한 치료 방법이라고 생각하고 있다. Remote afterloading high dose rate brachytherapy (HDRB) is a new technology and needs new biological principle for time and dose schedule. Here, authors attempt to evaluate the technique and clinical outcome in 116 patients, 590 procedures peformed at Asan Medical Center for 3 years. From Sep. 1989 to Aug 1992, 471 procedures of intracavitary radiation in 58 patients of cervical cancer and 26 of nasopharyngeal cancer,79 intraluminal radiation in 12 of esophageal cancer, 11 of endobronchial cancer and 1 Klatskin tumor and 40 interstitial brachytherapy in 4 of breast cancer, 1 sarcoma and 1 urethral cancer were performed. Median follow-up was 7 months with range $1\~31$ months. All procedures except interstitial were performed under the local anesthesia and they were all well tolerated and completed the planned therapy except 6 patients. 53/58 patients with cervical cancer and 22/26 patients with nasopharynx cancer achieved CR. Among 15 patients with palliative therapy, $80{\%}$ achieved palliation. We will describe the details of the technique and results in the text. To evaluate biologic effects of HDRB and optimal time/dose/fractionation schedule, we need longer follow-up. But authors feel that HDRB with proper fractionation schedule may yield superior results compared to the low dose rate brachytherapy considering the advantages of HDRB in safety factor for operator, better control of radiation dose and volume and patients comfort over the low dose brachytherapy.

2000년 영덕군 홍역 유행시 유행 차이에 따른 2개 초등학교 일부 학생에 대한 역학 조사

박수경,김지희,이주연,나병국,김우주,정해관,Park, Sue-Kyung,Kim, Jee-Hee,Lee, Joo-Yeon,Na, Byoung-Kuk,Kim, Woo-Joo,Cheong, Hae-Kwan 대한예방의학회 2001 Journal of Preventive Medicine and Public Health Vol.34 No.2

Objectives : During March-May, 2000, a measles outbreak occurred at Youngduk, Korea. This county is divided into two areas with different historical and socioeconomic background. The outbreak occurred in one of these areas. We conducted a comparative epidemiologic study on the two areas in order to evaluate the factors related to the epidemic. Materials and Methods : We selected two groups, grades 3 and 5 in a primary schools in each area. We investigated outbreak-related factors using parent-questionnaires, the vaccination history from the student's health record and the records concerning the recent measles-outbreak from the local health center. Serologic test on measles-IgG and -IgM antibody was done. Results : The infection rate was 31.5% for the epidemic area and 3.7% for non-the epidemic area according to clinical or serological criteria (p<0.001). No difference was seen in the measles vaccination rate, residence at the time of vaccination or past measles infection history between the two areas. In the epidemic area, the attack rate for the 4-6 year-old MMR booster group(20.5%) was higher than the non-booster group(32.4%), but was not found significantly. Vaccine efficacy was 29.6% in the epidemic area and 87.0% in the non-epidemic area (p<0.001). The IgG level and positive rate were significantly different between the two areas (median 10727 IU/ml, 98.9% in epidemic area; median 346 IU/ml, 85.9% in the non-epidemic area, p<0.001). However, the IgG level and positive rate between the measles-cases and non-cases were not significantly different. Conclusions : This outbreak took place in mostly vaccinated children. These results suggest that a reduction of herd immunity for immunity failure after vaccination may be one of the feasible factors related to the outbreak pattern in the two areas. The results of the IgG level and positive rate suggest that re-establishment of a normal value for IgG level and of a qualitative method for IgG are needed.

극소 저체중 출생아에서 Synagis^Ⓡ (palivizumab) 접종이 respiratory syncytial virus 감염으로 인한 재입원에 미치는 영향

박수경,정유진,유혜수,안소윤,서현주,최서희,김묘징,전가원,구수현,이경훈,장윤실,박원순,Park, Soo Kyoung,Jung, Yu Jin,Yoo, Hye Soo,Ahn, So Yoon,Seo, Hyun Joo,Choi, Seo Hui,Kim, Myo Jing,Jeon, Ga Won,Koo, Soo Hyun,Lee, Kyung-Hoon,Chang, Yun 대한소아청소년과학회 2010 Clinical and Experimental Pediatrics (CEP) Vol.53 No.3

목 적 : 본 연구에서 저자들은 $Synagis^{(R)}$ 접종으로 극소 저체중 출생아에서 respiratory syncytial virus 감염으로 인한 재입원이 감소하는지 여부와 이러한 접종이 특히 효과적인 세부 그룹을 알아보고자 하였다. 방 법 : 2005년 1월부터 2007년 12월까지 3년간 서울 삼성병원 신생아 중환자실에서 입원 치료 후 생존하여 퇴원한 출생체중 1,500 g 미만의 극소 저체중 출생아 350명을 대상으로 퇴원후 1년까지 후향적으로 조사하여 생후 28일째 보조적 산소투여가 필요하였던 기관지폐이형성증 유무 및 $Synagis^{(R)}$ 접종 여부에 따라 RSV 재입원율을 비교하였고, BPD의 중증도 와 재태연령 및 출생체중을 세분하여 각 군별 RSV 재입원율의 차이를 비교 분석하였다. 결 과 : 전체 350명중 11명(3.1%)가 RSV로 인해 재입원하였고, 시나지스 미접종군에서 재입원율이 5.0%였던 반면, 접종군에 서 재입원율은 0.7%로 시나지스 접종에 의해 RSV 재입원율이 86% 감소하였다(P =0.02). 기관지폐이형성증이 있는 환아에서의 재입원율은 접종군에서 0.7%, 미접종군에서 5.2%로 접종군에서 유의하게 감소되었고(P =0.045), 기관지폐이형성증이 없는 환아에서의 재입원율 또한 통계학적 유의성은 확인할 수 없었으나(P =0.35), 접종군에서는 0%, 미접종군에서는 4.9%로 접종군에서 감소하였다. 결 론 : 극소 저체중 출생아에서 시나지스 접종은 RSV로 인한 재입원율을 감소시켰고, 기관지폐이형성증 유무 및, 출생주수, 출생체중에 상관없이 재입원율의 감소 추세가 확인되었다. Purpose : The aim of this study was to determine the efficacy of $Synagis^{(R)}$ (palivizumab) in reducing the respiratory syncytial virus (RSV) readmission rate in very low birth weight infants (VLBWI ) and the subgroup that showed the most effective vaccination. Methods : We enrolled 350 VLBWI who had been discharged alive from the neonatal intensive care unit of Samsung Medical Center from January 2005 to December 2007 and were followed up for at least one year. A retrospective study based on medical records was performed for a period of one year after discharge. RSV readmission rate was investigated according to BPD (bronchopulmonary dysplasia, requiring oxygen at postnatal day 28) and $Synagis^{(R)}$ prophylaxis. We categorized the subgroups by the severity of BPD gestational age, and birth weight and compared the RSV readmission rates between subgroups. Results : Eleven VLBWI were readmitted. $Synagis^{(R)}$ prophylaxis resulted in a 86% reduction in the rate of readmission due to RSV infection (prophylaxis group, 0.7% and no prophylaxis group, 5.0%; P =0.02). Readmission rate in BPD patients was also reduced in the prophylaxis group (0.7% in the prophylaxis group vs. 5.2% in the no prophylaxis group, P =0.03). The readmission rate in patients without BPD was reduced in the prophylaxis group (0% in the prophylaxis group vs. 4.9% in the no prophylaxis group, P =1.00), but this was not statistically significant.Conclusion : $Synagis^{(R)}$ prophylaxis was effective at reducing RSV readmission in VLBWI. Its efficacy was verified irrespective of BPD, gestational age, or birth weight.

임의의 임피던스를 갖는 단순현가방식 가선계의 파동현상

박수경,김시문,김양한,Park, Sukyung,Kim, Seamoon,Kim, Yang-Hann 대한기계학회 1996 大韓機械學會論文集A Vol.20 No.11

The characteristics of wave propagation along a catenary depend on various impedance conditions; i.e., spatial impedance of catenary, impedance of boundaries. In this study, wave propagation along a simple catenary system is studied with arbitrary impedance conditions such as impedance of pantograph, boundary, catenary etc. Seven coupled equations which determine the characteristics of wave propagation along catenary system have been derived and numerically solved. Results demonstrate the role of each impedance condition in the dynamics of catenary system, i.e. the way in which the conditions affect waves on catenary as well as contact force of pantograph. The formulation and suggested solution method can be certainly used for desinging an optimal catenary system for a given pantograph.

노후주거지의 특성에 따른 '길'의 디자인 연구

박수경,문정민,Park, Su-Kyoung,Moon, Jeong-Min 한국주거학회 2015 한국주거학회 논문집 Vol.26 No.2

The 'pathways' in the Deteriorated Residential Area is the valuable place which represents the history of the community. The 'pathways' is the physical boundary which connects individual environment of private residential area to public environment and which has value as a medium for the definite site for regeneration of Deteriorated Residential Area. Thus, the 'pathways' is considered as the perfect material for the public design for spatial culture to regenerate the Deteriorated Residential Area. However, the most of the public design projects utilize the 'pathways' fragmentarily, there are few systematic studies based on the attribute of the Deteriorated Residential Area. The purpose of this study is the consideration on the attributes of the 'pathways', the detection of the spatial characteristics to find application of the 'pathways', and the cultivation of the baseline data for further research for the spatial nature of the Deteriorated Residential Area. For this study, theoretical consideration is practiced in advance to analyze the meaning of the 'pathways' and Deteriorated Residential Area, the case research is performed using design elements as the analytic frame, and the approach is inferred for systematic public design based on the above result. The objects of case research were chosen among the latest projects implemented in the Deteriorated Residential Area whose subject was 'pathways' and which showed successful result. The characteristics of them were investigated and the details were examined through the homepages of the projects, the reports related to the projects, research material, and interview with the people involved. And to conclude, 'pathways' represents the composition of contents, the space of movement, the formation of community, the landscape design, and the participatory design in the Deteriorated Residential Area. The 'pathways' also finds the proper secondary cultural material for the spatial characteristics and can create the space for the various movements, stay, and communication using the characteristics of movements. The narrow and closed space should be utilized actively to be altered into beautiful space and the Deteriorated Residential Area should be regenerated into coexistent design where people share their lives through sharing spaces.

인체 균형기능의 정량화와 진단시스템

박수경,Park, Su-Gyeong 재료연구소 2006 機械와 材料 Vol.18 No.3

OES를 이용한 질화막/산화막의 식각 스펙트럼 데이터 분석

박수경,강동현,한승수,홍상진,Park, Soo-Kyoung,Kang, Dong-Hyun,Han, Seung-Soo,Hong, Sang-Jeen 한국전기전자재료학회 2012 전기전자재료학회논문지 Vol.25 No.5

As semiconductor device technology continuously shrinks, low-open area etch process prevails in front-end etch process, such as contact etch as well as one cylindrical storage (OCS) etch. To eliminate over loaded wafer processing test, it is commonly performed to emply diced small coupons at stage of initiative process development. In nominal etch condition, etch responses of whole wafer test and coupon test may be regarded to provide similar results; however, optical emission spectroscopy (OES) which is frequently utilize to monitor etch chemistry inside the chamber cannot be regarded as the same, especially etch mask is not the same material with wafer chuck. In this experiment, we compared OES data acquired from two cases of etch experiments; one with coupon etch tests mounted on photoresist coated wafer and the other with coupons only on the chuck. We observed different behaviors of OES data from the two sets of experiment, and the analytical results showed that careful investigation should be taken place in OES study, especially in coupon size etch.

중학교 과학수업을 위한 주제중심 통합단원의 개발 및 효과 분석

박수경,김상달,주국영,남윤경,Park, Soo-Kyong,Kim, Sang-Dal,Ju, Gook-Yong,Nam, Youn-Kyong 한국지구과학회 2001 한국지구과학회지 Vol.22 No.5

본 연구에서는 간학문적 통합 방식의 주제중심 통합과학 단원을 개발하고 중학교 과학 수업에 적용하여 그 효과를 분석하였다. 관련 선행연구와 교과서 분석을 통하여 ‘상호작용’과 ‘안정성’의 두 가지 통합주제를 선정한 후 과학 네 영역을 포괄하여 주제와 관련된 주개념과 하위개념을 추출하고 해당 학습내용을 통합적으로 구성하였다. 통합주제가 상호작용인 경우 추출된 과학 각 영역별 주개념과 이와 관련되는 하위개념들이 높은 연계성을 가지도록 구성되었으나 통합주제가 안정성인 경우 주개념과 하위개념들을 서로 관련짓는데 어려움이 많았다. 즉 안정성이라는 통합주제는 상호작용이라는 통합주제보다 교과내용을 관통하는 연계성을 마련하기가 어려웠다. 개발된 주제중심 통합과학 단원을 실험집단인 중학교 3학년 2개 학급을 대상으로 운영하고, 전통적인 분과형 수업을 실시한 통제집단과 비교한 결과는 다음과 같다. 첫째, 주제중심 통합과학 수업과 전통적인 분과형 과학수업이 과학 성취도에 미치는 효과를 검증한 결과, 통합과학 수업이 분과형 과학수업에 비해 중학생들의 과학 성취도에 긍정적인 효과를 미친 것으로 나타났다. 둘째, 주제중심 통합과학 수업이 과학에 대한 태도에 미치는 효과를 검증한 결과, 과학수업의 즐거움 범주에서 통합과학 수업의 효과가 나타났으나 과학적 탐구에 대한 태도 범주와 과학적 태도의 적용 범주에서는 효과가 나타나지 않았다. 셋째, 주제중심 통합과학 수업에 대한 인식 조사 결과 전체적으로 긍정적인 것으로 나타났다. 하위 범주별로는 통합과학 수업시 학생의 참여 정도와 통합과학 수업에 대한 학습자의 흥미, 동기유발이 높게 평가되었으며, 학습자들이 통합과학 학습을 하는데 아직 어려움을 겪는 것으로 밝혀졌다.층서대는 Neognathodus roundyi 대로 지정될수있다. 이 생층서대와 금천층 코노돈트는 금천층의 지질시대가 북아메리카의 일리노이 분지에 분포하는 중기 석탄기의 더모이네시안 조(Desmoinesian stage)에 대비됨을 지시한다. 능력 없이도 특정 지식만 있으면 해결되는 문항이다. 반면에 정답률이 낮은 문항은 지구와 행성의 운동, 해파에 관한 문항이며, 특히 복합개념이 요구되는 문항의 정답률이 낮다. 학생의 오답 반응 분석 결과 기본 개념에 대한 이해가 미흡한 주요 내용은 공통과학에서는 변환단층 및 부정합에서 지질학적 현상, 혼합층과 수온 약층의 의미, 온대저기압 통과 전후의 날씨 변화이며, 지구과학 II 에서는 달의 위상과 위치변화, 화성암의 구성광물 ${\cdot}$ 화학조성 ${\cdot}$ 조직 변화와 마그마 분화 및 풍화와의 관계, 지진파 주시곡선, 대기순환의 종류와 규모, 해파, 혼합층과 수온 약층, 서안강화 현상, 행성의 위치와 운동, H-R도상에서의 별의 특성과 진화 등이다. 탐구 과정에 대한 학생의 성취도는 비교적 높으므로 이해도가 상대적으로 낮은 영역에 대해 학생의 오답 유형을 참고하여 기본 개념 지도에 보다 관심을 기울일 필요가 있다.Cr은 FW에서 전반적으로 감소하는 경향을 보였지만 SW에서는 실험 초기에 감소하다 24시간 이후에는 증가 후 일정한 양상을 보였다. Pb은 FW에서 전반적으로 감소했지만 SW에서는 초기에 급격히 증가 후 다시 급격히 감소하는 양상을 보였다 Pb 또한 Cu, Cd, As와 마찬가지로 SW1&2에서 제거속도가 가장 빠르게 나타났다. FW 상층수 중 Hg는 시간에 따라 급격히 감소했고 The purpose of this study is to develop theme-based integrated science unit by the interdisciplinary approach and to analyze it's effects on the science achievement and the attitude towards science learning. 'Interaction' and 'Stability' were selected as the integrated themes, and the main concept and subconcept in relation to the themes were extracted from the four areas of science, and the learning contents were constructed in the integrated ways. While the main concept have relevance to subconcept in the interaction, the main concept have little relevance to subconcept in the stability. Therefore, the stability was to fit with middle school integrated science theme, but the interaction was not. The theme-based integrated science units developed was implemented in middle school, and the results are follows. First, the science achievement of group of theme-based integrated science teaching is significantly higher than those of group of traditional teaching. Second, the scores of the test of attitude toward science learning of the group of theme-based integrated science teaching is significantly higher than those of group of traditional teaching. Third, the students' perception of theme-based integrated science teaching was positive. The students have participation, interest, motivation in theme-based integrated science teaching, and students have difficulty in learning theme-based integrated science teaching.