광간섭단층촬영으로 분류된 미만성 당뇨황반부종의 위험인자

김도형,김상훈,김현웅,윤일한,Do Hyung Kim,M,D,Sang Hoon Kim,M,D,Hyun Woong Kim,M,D,Ill Han Yoon M,D 대한안과학회 2006 대한안과학회지 Vol.47 No.4

Purpose: Recently diffuse diabetic macular edema has been morphologically classified by optical coherence tomography. This study was conducted to examine the difference of risk factors of the classified types of diffuse macular edema. Methods: The subjects included 93 people who were diagnosed with non-insulin dependent diabetes. We diagnosed the presence of diabetic macular edema with slit lamp fundus examination and used OCT for the classification of diffuse macular edema. We examined the differences in epidemiological risk factors in non-diabetic macular edema patients after diabetic macular edema patients were examined with fluorescein angiography to confirm diffuse macular edema. Results: Diabetic macular edema was classified into 4 types using OCT. Compared with patients without macular edema, sponge-like macular edema - related epidemiological risk factors included diabetic nephropathy, cystoid macular edema was related to HbA1c, serous macular detachment was related to treatment of diabetes by insulin, and posterior hyaloid raction was related to diastolic blood hypertension. Conclusions: In the present study, differences in epidemiological risk factors were related to the occurrence of a type of diffuse macular edema.

백굴채(Chelidonium majus) 추출물의 Fischer 344/N 랫드를 이용한 90일간 반복 경구투여 독성시험

김도형,장호송,김광호,강상철,김학수,길기현,공광한,안태환,배진숙,고현규,김갑호,박찬구,이현걸,송시환,한충택,Kim, Do-Hyung,Zhang, Hu-Song,Kim, Kwang-Ho,Kang, Sang-Chul,Kim, Hak-Soo,Gil, Ki-Hyun,Kong, Kwang-Han,Ahn, Tae-Hwan,Bae, Jin-Sook,Go, Hyeon-K 대한수의학회 2009 大韓獸醫學會誌 Vol.49 No.1

This study was performed to evaluate repeated-dose oral toxicities of Chelidonium majus extract in Fischer 344/N rats. Chelidonium majus extract was administered orally to rats at dose levels of 0, 25, 74, 222, 666 and 2,000 mg/kg/day. Each group consisted of 10 rats of each gender. The Chelidonium majus extract was given once a day, 5 times a week, for 90 day repeatedly. This study was conducted in accordance with the Protocol of Korea National Toxicology Program (issued by National Institute of Toxicological Research) and The Standards of Toxicity Study for Medicinal Products (issued by Korea Food and Drug Administration). In the present study, There were no toxicologically significant changes in mortality, clinical signs, body weight gains, ophthalmoscopy, urine analysis, hematology, serum biochemistry, necropsy findings, organ weights, histopathology, estrus cycle and sperm examination of all animals treated with Chelidonium majus extract. These results suggest that the oral no observed adverse-effect level of the test item, Chelidonium majus extract, in rats is higher than 2,000 mg/kg/day in both genders. The target organs were not established.

전공의 의료커뮤니케이션 능력과 진료수행 자기효능감, 공감능력과의 상관관계

김도형,김민정,이해영,김현석,김영미,이상신,Kim, Doehyung,Kim, Min-Jeong,Lee, Haeyoung,Kim, Hyunseuk,Kim, Youngmi,Lee, Sang-Shin 한국정신신체의학회 2021 정신신체의학 Vol.29 No.1

연구목적 전공의 공통역량으로서 의료커뮤니케이션의 중요성을 환기시키기 위하여 전공의를 대상으로 의료커뮤니케이션 능력을 조사하고 의료커뮤니케이션 능력, 진료수행 자기효능감 그리고 공감능력의 관련성을 분석하고자 하였다. 방 법 일 대학병원 소속 총 106명 전공의를 대상으로 자기평가 의료커뮤니케이션 능력, 수정된 진료수행 자기효능감 척도, 한국판 의사 공감 척도를 조사하였다. 성별, 나이, 전공과목(인턴, 내과계, 외과계), 연차(인턴, 1~2년차, 3~4년차)에 따른 의료커뮤니케이션 능력의 차이를 조사하였다. 상관분석으로 의료커뮤니케이션 능력, 수정된 진료수행 자기효능감, 공감능력의 상관계수를 구하였고 구조방정식 모형을 이용하여 의료커뮤니케이션 능력에 영향을 미치는 각 변수의 효과를 검증하였다. 결 과 인턴 31명(31.6%), 내과계 레지던트 45명(45.9%), 외과계 레지던트 22명(22.4%)으로 총 98명이 참가하였다. 성별, 나이, 전공과목, 연차에 따른 자기평가 의료커뮤니케이션 능력 점수는 통계적으로 유의한 차이가 없었다. 의료커뮤니케이션 능력은 수정된 진료수행 자기효능감(r=0.782, p<0.001) 및 공감능력(r=0.210, p=0.038)과 유의한 정적 상관관계가 있었다. 공감능력은 진료수행 자기효능감에 직접적으로 유의한 영향을 미쳤으며(β=0.30, p<0.01), 진료수행 자기효능감은 의료커뮤니케이션 능력에 직접적으로 유의한 영향을 보였다(β=0.80, p<0.001). 공감능력은 진료수행 자기효능감을 매개하여(β=0.26, p<0.05) 간접적으로 의료커뮤니케이션 능력에 영향을 미치고 있었다. 결 론 전공의 의료커뮤니케이션 능력은 성공적 진료를 위해 필요한 진료수행 자기효능감과 직접적 연관성이 있었으므로 전공의 공통교육과정의 하나로서 중요한 위치를 차치한다고 할 수 있다. 그리고 현재의 의료커뮤니케이션 모델은 공감 능력과는 구별해서 이해될 필요가 있음이 시사된다. Objectives : This study evaluated the medical communication skills of trainee doctors and analyzed the relationship between medical communication skills, self-efficacy on clinical performance (SECP) and empathy. Methods : A total of 106 trainee doctors from a university hospital participated. The questionnaire comprised self-evaluated medical communication skills, modified SECP and the Korean version of the Jefferson Scale of Empathy-Health Professionals version. The mean difference in medical communication skills scores according to gender, age, division (intern, internal medicine group or surgery group) and position (intern, first-/second- and third-/fourth-year residents) were analyzed. Pearson correlation coefficients were determined between medical communication skills, modified SECP and empathy. The effects of each variable on medical communication skills were verified using the structural equation model. Results : There were no statistically significant mean differences in self-evaluated medical communication skills according to gender, age, division or position. Medical communication skills had a significant positive correlation with modified SECP (r=0.782, p<0.001) and empathy (r=0.210, p=0.038). Empathy had a direct effect on modified SECP (β=0.30, p<0.01) and modified SECP had a direct effect on medical communication skills (β=0.80, p<0.001). Empathy indirectly influenced medical communication skills, mediating modified SECP (β=0.26, p<0.05). Conclusions : Medical communication skills are an important core curriculum of residency programs, as they have a direct correlation with SECP, which is needed for successful treatment. Moreover, the medical communication needs a new understanding that is out of empathy.

옥수수 가공방법 및 두께가 in situ 건물 분해율과 in vitro 메탄 발생에 미치는 영향

김도형,이창현,우양원,김종남,조광현,장선식,김경훈,Kim, Do Hyung,Lee, Chang Hyun,Woo, Yang Won,Rajaraman, Bharanidharan,Kim, Jong Nam,Cho, Kwang Hyeon,Jang, Sun Sik,Kim, Kyoung Hoon 한국초지조사료학회 2017 한국초지조사료학회지 Vol.37 No.4

본 연구에서는 옥수수의 가공방법 및 옥수수의 두께의 차이가 반추위 in situ 소화율 및 in vitro 반추위 발효와 메탄 발생에 미치는 영향에 대하여 알아보고자 실시하였다. Micronized corn(2.5 mm thickness) 처리구는 다른 처리구들에 비하여 in situ 48시간 건물 분해율이 모든 배양시간대에서 높게(P<0.05) 나타났다. 반면, steam flaked corn(3.3 mm thickness) 처리구는 모든 배양시간대에서 가장 낮은(P<0.05) in situ 건물 분해율을 보였다. 반추위 내에서 미생물에 의해 분해되는 b fraction은 이와 상반되는 결과인 steam flaked corn(3.1 mm thickness)과 steam flaked corn(3.3 mm thickness) 처리구에서 높게(P<0.05) 나타났다. b fraction이 반추위를 통과하는 속도인 건물 분해상수 k값은 micronized corn(2.5 mm thickness) 처리구에서 가장 높게 (P<0.05) 나타났고 steam flaked corn(3.3 mm thickness) 처리구에서 가장 낮게 (P<0.05) 나타났다. 반추위내 시간당 통과속도를 0.05로 적용한 유효 건물 분해도는 건물 분해상수와 유사하게 micronized corn(2.5 mm thickness) 처리구에서 가장 높게 (P<0.05), steam flaked corn(3.3 mm thickness) 처리구에서 가장 낮게(P<0.05) 나타났다. In vitro 반추위 48시간 건물 소실율은 micronized corn(2.5 mm thickness) 처리구에서 가장 높은 경향을(P=0.088) 보인 반면 steam flaked corn 처리구들 사이에서는 두께에 따른 건물 소실율의 상관관계는 나타나지 않았다. 총 가스발생량 및 메탄 발생량에 있어서도 건물 소실율과 같은 결과인 micronized corn(2.5 mm thickness) 처리구에서 가장 높게 나타났으며(P=0.001), 총 휘발성지방산은 steam flaked corn(2.9 mm thickness)의 처리구에서 가장 높게 나타났으나(P=0.015) 나머지 처리구들에서는 유의적인 차이를 보이지 않았다. aectate: propionate의 비율 또한 steam flaked corn(2.9 mm thickness)의 처리구에서 가장 높게, micronized corn(2.5 mm thickness) 처리구에서 가장 낮게 나타났다(P=0.008). 본 연구의 결과를 종합하면 steam flaked corn 처리구들에서 in vitro 휘발성지방산 농도에 있어 in situ 반추위내 건물 분해상수와 유효 건물 분해도의 결과와 비교하여 상관관계가 나타나지 않은 결과로 유추해 보면 옥수수 가공방법에 의한 두께의 차이는 반추위 메탄 발생량에 영향을 미치지 않은 것으로 판단된다. This study was conducted with two ruminally cannulated Holstein steers to examine the effect of micronized and steam flaked corn on ruminal fermentation characteristics. The in situ dry matter degradability after 48 h incubation was the highest (P<0.05) at micronized corn (2.5 mm thickness) compared with steam flaked corn treatments. The steam flacked corn (3.3 mm thickness) was degraded lower (P<0.05) than the 2.9 and 3.1 mm thickness of steam flacked corn. Effective dry matter degradability and the rate of constant were the highest (P<0.05) at micronized corn (2.5 mm thickness) compared with steam flaked corns as well. The in vitro dry matter degradability after 48 h incubation was tended to higher (P=0.088) at micronized corn (2.5 mm thickness) than steam flaked corns, whereas there is no significantly difference between steam flaked corn treatments. Total volatile fatty acid concentration was higher at steam flaked corn (2.9 mm thickness) than micronized corn (2.5 mm thickness) and steam flaked corn (3.1 and 3.3 mm thickness). The acetate : propionate ratio was the highest (P=0.008) at steam flaked corn (2.9 mm thickness) and the lowest (P=0.008) at micronized corn (2.5 mm thickness). Total gas and methane production after 48h ruminal incubation was the highest (P=0.001) at micronized corn (2.5 mm thickness) compared with steam flaked corns. According to these results, the thickness of steam flaked corn as resulted corn processing is believed to do not affect methane production. However, further study is needed to better understand the present results to verify the correlation between corn processing method and their thickness on methane production using the same thickness corns by difference processing methods.

실시간 운영체제 Qplus-P용 그래픽 윈도우 라이브러리 구현

김도형,김선자,김성우,Kim, Do-Hyung,Kim, Sun-Ja,Kim, Seung-Woo 한국정보처리학회 2003 정보처리학회논문지 A Vol.10 No.5

디지털 TV, 인터넷 셋탑박스, 인터넷 전화기 등과 같은 정보가전 제품이 속속 등장하면서 이들 제품의 기능을 제어하는데 필수적인 실시간 운영체제 시장이 크게 성장하고 있다. 한국전자통신연구원에서는 소형의 휴대 정보 단말에서부터 디지털 셋탑박스 및 홈 서버까지 다양한 종류의 정보가전 기기에 공통으로 사용될 수 있는 확장 가능한 표준 실시간 운영체제 Qplus-P를 개발하였다. 본 논문에서는 정보가전용 실시간 운영체제 Qplus-P에 탑재되는 그래픽 윈도우 라이브러리의 구현에 대해 기술한다. Qplus-P 그래픽 윈도우 라이브러리는 공개소스인 tiny-X 그래픽 서버에 한글 처리 기능, 화면 회전 기능, 터치스크린 입력 기능, 그래픽 가속 기능 등을 추가하였다. Qplus-P 그래픽 윈도우 라이브러리는 현재 arm 프로세서를 사용하는 아이팩 3600 PDA, 삼성 S3C2400 보드, 자우루스 PDA와 x86 프로세서를 사용하는 홈서버에 탑재되었으며, Qplus-P타겟 빌더에 통합된 형태로 제공된다. As the Internet appliances like digital TV, Internet set-top boxes, and Internet phone, are showing up in the market, the economics of real-time operating system (RTOS), which is an essential for controlling those devices, is expanding faster than ever before. ETRI has developed describes RTOS called Qplus-P, targeting various platforms ranging from PDA to Internet set-top box and home server. This paper describes the implementation of graphic window library for Qplus-P. The Qplus-P graphic window library was implemented using tiny-X graphic server and gtk graphic toolkit, which are open source software. To port this library to various aliances, hangul processing, screen rotation, touch screen, and graphic acceleration functions are added to the tiny-X graphic server of the implementd graphic window library. Currently, Qplus-P graphic window is running on ARM-based appliances such as iPaq PDA, Samsung S3C2400 board, Zaurus PDA, and on Home Server that uses x86 processor. Qplus-P graphic library is provided as a of Qplus-P target builder.

EL/IX 단계 3을 적용한 실시간 운영체제 Qplus-P용 C 표준 라이브러리의 설계 및 구현

김도형,신창민,박승민,Kim, Do-Hyung,Shin, Chang-Min,Park, Sung-Min 한국정보처리학회 2002 정보처리학회논문지 A Vol.9 No.4

As the products of internet appliance, such as digital TV, internet set-top box, and internet phone, are continually produced, the market of real time operating system which controls those products is being highly increased. ETRI developed the extensible real time operating system, Qplus-P, which can be used from PDA to internet set-top box and home server. This paper describes the design and implementation of C standard library for real-time operating system Qplus-P. The Qplus-P C standard library follows EL/IX API level, which is proposed to the real-time operating system international standard by the RedHat. And, the C standard library functions, which are needed to support the Tiny-X and Kaffe, are also implemented. The implemented C standard library can reduce the size of library about 30% compare to the C library that does not follow EL/IX API level. 디지털 TV, 인터넷 셋탑박스, 인터넷 전화기 등과 같은 정보가전 제품이 속속 등장하면서 이들 제품의 기능을 제어하는데 필수적인 실시간 운영체제 시장이 크게 성장하고 있다. 한국전자통신연구원에서는 소형의 휴대 정보 단말에서부터 디지털 셋탑박스 및 홈 서버까지 다양한 종류의 정보가전 기기에 공통으로 사용될 수 있는 확장 가능한 표준 실시간 운영체제 Qplus-P를 개발하였다. 본 논문에서는 정보가전용 실시간 운영체제 Qplus-P에 탑재되는 C표준 라이브러리의 설계 및 구현에 대해 기술한다. Qplus-PC표준 라이브러리는 레드햇에서 실시간 운영체제 국제 표준으로 제안된 EL/LX 응용 프로그램 인터페이스 단계에 따라 설계되었다. 그리고 Qplus-P 응용 프로그램 수행에 필요한 Tiny-X, 카페 등을 지원하기 위해 추가적으로 필요한 함수들도 구현되었다. 구현된 C표준 라이브러리는 EL/IX 응용프로그램 인터페이스 단계를 적용하지 않은 C표준 라이브러리보다 라이브러리 크기를 30% 정도 줄일 수 있었다.

고성능 역전기투석을 위한 세공충진 음이온교환막의 개발

김도형,송현비,윤경석,강문성,Kim, Do-Hyeong,Song, Hyeon-Bee,Yoon, Kyungseok,Kang, Moon-Sung 한국막학회 2022 멤브레인 Vol.32 No.5

Reverse electrodialysis (RED) is one of the promising eco-friendly renewable energy technologies which can generate electricity from the concentration difference between seawater and freshwater by using ion-exchange membranes as a diaphragm. The ion-exchange membrane is a key component that determines the performance of RED, and must satisfy requirements such as low electrical resistance, high permselectivity, excellent durability, and low manufacturing cost. In this study, pore-filled anion-exchange membranes were fabricated using porous polymer substrates having various thicknesses and porosity, and the effects of ion-exchange polymer composition and membrane thickness on the power generation performance of RED were investigated. When the electrical resistance of the ion-exchange membrane is sufficiently low, it can be confirmed that the RED power generation performance is mainly influenced by the apparent permselectivity of the membrane. In addition, it was confirmed that the apparent permselectivity of the membranes can be improved through IEC, crosslinking degree, membrane thickness, surface modification, etc., and the optimum condition must be found in consideration of the trade-off relationship with electrical resistance.

3D 게임 그래픽스 엔진에서의 실시간 그림자 처리 기술들

김도형,Kim, Do-Hyeong 대한전자공학회 2007 전자공학회지 Vol.34 No.10

Analysis and removal of the stench emitted from indoor dust

김도형,Yeon-Hong Kim,Hana Jung,선우창신 한국화학공학회 2010 Korean Journal of Chemical Engineering Vol.27 No.2

The offensive odor produced from indoor dust accumulated inside a vacuum cleaner is quite unpleasant to the user. In this study, the odor of dust samples prepared under various conditions was examined using an olfactory method that employs the human sense of smell. In addition, the odorous compounds were analyzed by GC-MS. The odor intensity of the dust collected inside the vacuum cleaner increased in proportion to not only the humidity and temperature of the dust, but also to the cleaning period of the container where indoor dust was accumulated. GC/MS confirmed aldehydes to be the main odorous compounds. The dilution ratio at which the stench of the indoor dust was not detected was determined by using the triangle odor bag method.

사상체질에 따른 뇌혈관질환 위험인자의 분포에 대한 비교연구

김도형,윤성우,고창남,김승은,Kim, Do-Hyung,Yun, Seong-Woo,Ko, Chang-Nam,Kim, Seung-Eun 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.3

Objectives: Many studies have been reported about Sasang constitutional distribution of cerebrovascular disease(CVD) patients. But there has been little study about the risk factors of normal persons between Sasang constitutions. So we studied to evaluate the risk of CVD between Sasang constitutions. Methods: We retrospectively studied subjects without previous stroke($age{\geq}40$) who visited east-west medical examination center in Kang Nam Korean Hosipital, Kyung Hee University for last 2 years(1998.8.1.${\sim}$2000.7.31.). Sasang constitutional differentiation was performed by Questionnaire for the Constitution Classification(QSCC) II and subjects who couldn't be classifiea by QSCC II were excluded. Results : Total 363 subjects participated in this study(Taeyangin 0, Taeumin 103, Soyangin 113, Soumin 92, obscure 55). Diabetes mellitus(p<0.05), hyperlipidemia(p<0.01), obesity(p=0.000) were significantly prevalent in Taeumin. Hypertension and heart disease had no significant difference between Sasang constitutions. Conclusions: This study showed that the risk factors of CVD were more prevalent in Taeumin. Therefore we guess that Taeumin has high risk of CVD.