Three-Dimensional Porous Collagen/Chitosan Complex Sponge for Tissue Engineering

Kim, Sung Eun,Cho, Yong Woo,Kang, Eun Jung,Kwon, Ick Chan,Lee, Eunhee Bae,Kim, Jung Hyun,Chung, Hesson,Jeong, Seo Young The Korean Fiber Society 2001 Fibers and polymers Vol.2 No.2

A three-dimensional, porous collagen/chitosan complex sponge was prepared to closely simulate basic extracellular matrix (ECM) constitutes, collagen and glycosaminoglycan. The complex sponge was prepared by a lyophilization method and had the regular network with highly porous structure, suitable for cell adhesion and growth. The pores were well interconnected, and their distribution was fairly homogeneous. The complex sponge was crosslinked using 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS) to increase its boilogical stability and enhance its mechanical properties. The crosslinking medium has a great effect on the inner structure of the sponge. The homogeneous, porous structure of the sponge was remarkably collapsed in an aqueous crosslinking medium. However, the morphology of the sponge remained almost intact in a water/ethanol mixture crosslinking milieu. Mechanical properties of the collagen/chitosan sponge were significantly enhanced by EDC-mediated crosslinking. The potential of the sponge as a scaffold for tissue engineering was investigated using a Chinese hamster ovary cell (CHO-K1) line.

자기진단형 위상제어에 의한 단상유도전동기의 특성 및 모니터링 시스템에 관한 연구

조금배,박수강,백형래,임양수,이성길 조선대학교 에너지.자원신기술연구소 2003 에너지·자원신기술연구소 논문지 Vol.25 No.2

The three-phase induction motor is rugged, reliable, long-lived, self-starting, smooth-running. But it is relatively inexpensive and three-phase power in not available everywhere, so if possible we need single-phase motor with the same characteristics. In fact, single-phase induction motors have excellent characteristics and outnumber the three-phase variety. Most of the small electric motors used in home, farm, or office are single-phase induction motors of one type or another. This electric motors application field need most energy saving type drive according to enlargement of electronic goods and to tend high class. The paper is proposed a various phase control methods for energy saving of single- phase induction motor. The controllers that are embodied by each method can use by various usage according to each performance and it is considered that application may help in the electrical energy saving because is possible to other electrical appliances.

개에서 관찰된 모기질세포종의 증례보고

조성환,손화영,김혜성,최종윤,류시윤,박배근,윤원기,홍성혁,김덕환 충남대학교 수의과대학 동물의과학연구소 2002 動物醫科學硏究誌 Vol.10 No.-

Pilomatricoma was histopathologically diagnosed in a 2.5-year-old male Alaskan malamute. The patient was referred to Chungnam National University, Veterinary Medical Teaching Hospital with solitary, firm and well-circumscribed mass at shoulder. Grossly, the mass was dome shaped to tumor like and 10 x 8 x 5㎝ in size. Some lesions had gritty or bony consistency and was chalky when sectioned Histopathologic feature included mumerous clusters of tightly arranged, basaloid cells with evenly distributed chromatin and ghost cells were characterized by a central unstained zone. The ghost cells often become calcified and osseous metaplasia was also present.

Mo 화학기상증착에 있어서 불순물 농도에 미치는 증착조건의 영향

배상석,서성교,홍은식,김승모,조미정,한혜정,이두성,김세훈,민석홍 국립7개대학공동논문집간행위원회 2001 공업기술연구 Vol.1 No.-

The thermal decomposition process of Mo(CO)_6 on chemical vapor deposition was investigated by analyzing the effects of deposition temperature, pressure, and reaction gas on the phase change of deposited films. Mo_2C was deposited at or below 350℃ due to the incompleteness of thermal decomposition of Mo(CO)_6, but Mo films was successfully deposited at 400℃ or higher temperatures. The variation of deposition pressure did not change the dependence of decomposition process on deposition temperature. The activation energy of surface reaction was 5.8 ㎉/mole.

소아 재발성 호흡기 감염증에서 Broncho-Vaxom�의 임상효과

배종우,차성호,조병수,정사준,최용묵,안창일 한국의학사 1990 診斷과治療 Vol.10 No.9

5급 와동에서 저유동성과 고유동성 레진의 변연 미세누출 비교

배상배,조영곤,이명선 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.6

이 연구는 1단계 자가부식 접착제와 저유동성 및 고유동성 레진을 이용한 5급 와동 수복물에서 법랑질과 상아질 변연의 미세 누출 차이를 상호 비교하기 위하여 시행하였다. 40개의 대구치의 협, 설면 치경부에 5급 와동을 형성하고, 8개씩 무작위로 선택하여 사용된 유동성 레진에 따라 5개의 군으로 분류하여 각 군의 와동을 유동성 레진으로 충전하였다 (대조군: Filtek Z 350, M-LF 군: Metafil Flo α, U-LF 군: Unifil LoFlo Plus, M-HF군: Metafil Flo, U-HF군: Unifil Flow). 각 군의 치아를 2% methylene blue용액에 24시간 동안 침적시킨 다음, 협면과 설면의 5급 수복물의 중앙부가 통과되도록 절단하였다. 각 군의 절단 시편에서 유동성 레진 수복물의 법랑질과 상아질 변연부를 광학 입체현미경 하에서 색소침투 정도를 관찰하여 미세누출 점수를 평가하였다. 본 연구의 결과, 1단계 자가부식 접착제와 유동성 레진을 이용하여 5급 와동을 충전한 경우, 고유동성 레진보다 저유동성 레진이 낮은 변연 미세누출을 나타내어 5급 와동에서 저유동성 레진의 사용이 추천된다. The purpose of this study was to compare the microleakage of low and high viscosity flowable resins in class V cavities applied with 1-step adhesives. Forty Class V cavities were prepared on the cervices of buccal and lingual surfaces of extracted molar teeth and divided into four groups (n=8). Cavities were restored with AQ Bond Plus /Metafil Flo α, G-Bond/ UniFil LoFlo Plus (Low flow groups), AQ Bond Plus/Metafil Flo and G-Bond/UniFil Flow (High flow group), respectively. Specimens were immersed in a 2% methylene blue solution for 24 hours, and bisected longitudinally. They were observed microleakages at the enamel and dentinal margins. In conclusion, the low viscosity flowable resins showed lower marginal microleakage than do the high vis cosity flowable resins in class V cavities.

지렁이 분변토로부터 황화수소 분해 균주의 분리 및 특성

배무,박상진,류희욱,조경숙,이은영 이화여자대학교 환경문제연구소 1997 이화환경연구 Vol.1 No.-

탈취제로 이용되고 있는 지렁이 분변토로 부터 황화수소를 제거하는 황산화 세균 CP-5를 분리하였다. 이 균주는 운동성이 없고 Gram 음성인 단간균 이었으며, cytochrome oxidase와 catalase test에 양성 반응을 보였다. CP-5 균주는 환원형 황합물을 기질로 하는 배지에서 독립영양적인 생장이 가능하였다. 이 균주는 thiosulfate 에서 tetrathionate를 중간생성물로 하여 최종적으로 sulfate로 산화하고, elemental sulfur를 일단 thiosulfate로 산화한 후, sulfate까지 재산화하는 것으로 사료되었다. 독립영양 배지에 yeast extract 를 첨가하면 균의 생장이 촉진되었다. CP-5 균주 현탁액에 H₂S를 2vvm의 유속으로 주입하면 140ppm까지는 거의 완전하게 제거 가능하였다. 본 연구결과로부터 CP-5 균주는 분변토에서 황화수소를 제거하는 대표적인 탈취균주이며, 황화수소 제거를 위한 생물학적 탈취 공정에 활용 가능하다는 것을 알 수 있었다. A new sulfur-oxidizing bacterium which was capable of degrading hydrogen sulfide was isolated from earthworm casts using deodorant materials. The cell of isolate CP-5 was short rod, gram negative and non-motile, the activities of cytochrome oxidase and catalase were positive. The isolate could autotrophically grow in the basal mineral medium supplemented the reduced sulfur compounds such as thiosulfate and elemental sulfur. This bacterium could oxidize thiosulfate and elemental sulfur to sulfate, and the metabolic intermediates were considered as tetrathionate and thiosulfate, respectively. The removal of hydrogen sulfide by the isolate CP-5 was confirmed, and the CP-5 was regarded as one of microorganisms responsible for degradation of hydrogen sulfide in earthworm casts. The isolate CP-5 can be applied to biodeodorization systems for the improvement of removal efficiency of hydrogen sulfide.

우리나라 연 작업자들의 연폭로 수준에 관한 연구

조인숙,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

To assess lead exposure in Korean lead workers, 2047 male lead workers in 17 lead using industries were studied. Study population were divided into 4 occupation categories such as storage battery industry(type 1), secondary smelting and litharge making industries(type 2), PVC stabilizer making industries(type 3) and primary smelting and related industries (type 4). Blood lead and zinc protoporphyrin in whole blood (ZPP) were selected as an index of lead exposure. Hemoglobin and hematocrit were also checked. Fifteen questionnaires of lead related symptoms were provided to all lead workers and filled up by themselves and confirmed by medical doctors. Personal variables such as age, work duration, smoking and drinking habits were also collected. the results were as follows. 1) The mean blood lead, ZPP and hemoglobin of all lead workers were 29.7+12.6㎍/100㎖, 56.5+38.6㎍/100㎖ and 14.6+1.3 gm/100㎖ respectively. 2) While the mean blood lead of lead workers in type 1, 2, 3 and 4 were 28.6+11.6㎍/100㎖, 46.2+15.3 ㎍/100㎖, 46.8+12.1 ㎍/100㎖ and 26.2+10.2 ㎍/100㎖, the mean value of blood ZPP of those workers were 53.6+32.6 ㎍/100㎖, 108.1+87.1 ㎍/100㎖, 98.9 +54.9 ㎍/100㎖ and 45.8+19.5 ㎍/100㎖ respectively. 3) The percents of lead workers whose blood lead were 40-59.9 ㎍/100㎖ and over 60.0 ㎍/100㎖ were 17.6% and 2.1% respectively. Those whose blood lead were 40-59.9 ㎍/100㎖ and over 60.0 ㎍/100㎖ were 15.18% and 0.96% for type 1, 43.59% and 21.79% for type 2, 58.89% and 12.22% for type 3 and 11.82% and 0% for type 4 respectively. 4) The percents of lead workers whose blood ZPP were 100-149 ㎍/100㎖ and over 150 ㎍/100㎖ were 5.17% and 3.17% respectively. Those whose blood ZPP were 100-149 ㎍/100㎖ and over 150 ㎍/100㎖ were 4.66% and 2.04% for type 1, 10.26% and 25.64% for type 2, 23.33 and 13.33% for type 3 and 1.28% and 0.32% for type 4 respectively. 5) The prevalence rate of smoking and drinking of male lead workers in all lead industries were 70.8% and 71.0% respectively. While the mean blood lead of smoker, non-smoker, drinker and non-drinker were 30.24+12.58 ㎍/100㎖, 28.35+12.7 ㎍/100㎖, 30.24 ㎍/100㎖ and 28.74 ㎍/100㎖ respectively, the mean blood ZPP of those were 55.7+37.1 ㎍/100㎖, 58.4+41.9 ㎍/100㎖, 55.7+36.5 ㎍/100㎖ and 58.4+43.3 ㎍/100㎖ respectively. 6) While the correlation of hematocrit corrected blood lead with other lead exposure variables were higher than non-corrected blood lead, the correlation of log-transformed ZPP with other lead exposure variables were higher than non-corrected blood ZPP. 7) The most frequent symptom among 15 lead related symptom questionnaires was 'general fatigue' and the next one was 'feeling irritated with disturbance' and least one was 'acute abdominal pain around the umbilicus' in all lead workers. The overall prevalence of lead workers in storage battery industry and primary lead smelting industry were higher than secondary lead smelting and PVC stabilizer making industries. 8) The prevalence of lead related symptoms was a little higher in 13 symptoms in smokers than non-smokers and in 14 symptoms in drinker than non-drinkers, but they were not statistically significant. 9) Stepwise multiple regression analysis, using overall symptom prevalence as a dependent variable blood lead, blood ZPP, hemoglobin, age, work duration, drinking and smoking habits as independent variables, indicated that smoking habit, drinking habit and age were significantly contributed to the dependent variable. 10) The slopes of simple linear regression of blood lead (independent variable) with blood ZPP and log-transformed ZPP as dependent variable were different among 4 types of lead industries. The slope of lead industries with low mean blood lead were less steeper than those with high mean blood lead.

MPEG-4 부호화 데이터의 객체 기반 입체 동영상 변환

조영란,박상훈,김만배 강원대학교 정보통신연구소 2003 정보통신논문지 Vol.7 No.-

In this paper, we propose new stereoscopic video conversion methodology that converts two-dimensional(2-D) MPEG-4 video to stereoscopic video. In MPEG-4, each image is composed of background object and primary object. In the first step of the conversion methodology, the camera motion type is determined for stereo image generation. For this, motion vectors of background object are utilized. In the second step, the object-based stereo image generation is accomplished. The background object makes use of a current image and a delayed image for its stereo image generation. On the other hand, the primary object uses a current image and its horizontally-shifted version to avoid the possible vertical parallax that could happen. Furthermore, URFA(Uncovered Region Filling Algorithm) is applied in the uncovered region which might be created after the stereo image generation of a primary object. In our experiment, we convert MPEG-4 test video to stereoscopic video based upon our proposed methodology and analyze its results.

서방형 Diltiazem제제의 개발을 위한 약동학/약력학적 특성 검토

유경상,배균섭,조주연,장인진,신상구 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2