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박상진,김수홍,정찬우,이일수 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.8
Idiopathic calcinosis of the scrotum appears in childhood as multiple, asymptomatic nodules of the scrotal skin that gradually increase in size and number and sometimes discharge a chalky material. Histopathologic examination shows calcific deposits of various sizes that are present in the dermis and often surrounded by foreign body granulomatous inflammation. The pathologic mechanism of this condition is not clear, but there is accumulating evidence for dystrophic calcification of cyst rather than an idiopathic genesis. Here we present a 34-year-old otherwise healthy man who had a 10-year history of multiple, asymptomatic, firm, subcutaneous nodules of the scrotal skin, which sometimes discharged a chalky material. The nodules were completely excised and 45 nodules were observed in the histopathologic examination. In addition to the typical findings of idiopathic calcinosis of the scrotum, seven intact cysts were observed among 45 nodules. Among the seven cysts there were five pilar cysts and two indeterminate cysts with diffusely calcified keratinous content and attenuated walls. A mixture of calcified keratinous material and inflammatory infiltrates was detected. These findings suggest that idiopathic calcinosis of the scrotum may be deriven from the dystrophic calcification of cysts.
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원형 탈모증 환자에서 DPCP 치료중 발생한 피부 묘기증 1 예
박상진,박경호,김수홍,이일수 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.7
Topical immunotherapy with Diphenylcyclopropenone (DPCP) appears to be an effective modality for the treatment of alopecia areata. Most common side effects of DPCP are severe contact dermatitis, lymphadenopathy, generalized pruritus, urticaria, dermatitis on the remote areas. Rarely, DPCP can induce vitiligo, contact urticaria, erythema multiforme. We describe a patient with alopecia areata who developed dermographism due to topical therapy with DPCP. A 17-year-old man visited our clinic with alopecia areata, which began to develop 5 years prior to his visit. After sensitization with 0.2% DPCP in acetone, DPCP was topically applied to the scalp every two weeks for 4 months. Because there was no sign of improvement, we halted DPCP therapy and commenced systemic corticosteroids. When the patient was rechallenged with DPCP immunotherapy after one year, the dermographism has occured. Treatment with oral antihistamines for 2 months improved dermographism.
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봉소염의 임상양상을 보인 비강의 T / NK - 세포 림프종 1 예
박상진,김수홍,이일수 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.8
T/NK-cell lymphoma shows biphenotype of the T-cell and NK-cell. This tumor is characterized by the absence of clonal rearrangement of T-cell receptor gene, frequent association with Epstein-Barr virus(EBV), poor clinical course, and common extranodal invasion. When the tumor did not involve nasal cavity, it is called nasal-type T/NK-cell lymphoma. It commonly appears as deep nodule, infiltrative plaque, and ulcerative plaque. We describe a case of nasal-type T/NK-cell lymphoma, associated with EBV, and showing clonal T-cell receptor y gene rearrangement. The patient was 60-year -old female with a skin lesion on her face, which resembled cellulitis.
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박상진,이동윤,김수홍,이일수 대한피부과학회 2002 大韓皮膚科學會誌 Vol.40 No.1
Cutaneous endometriosis is defined as the presence of extrauterine endometrial tissue in or under the skin. It occurs most commonly as a secondary process in scars after abdominal or pelvic procedures. Rarely, endometriosis may arise spontaneously within the umbilicus. We present a case of cutaneous endometriosis presented as a painful umbilical nodule. The patient had no history of previous abdominal or pelvic surgery. Histopathological examination revealed a characteristic feature of cutaneous endometriosis.
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