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      • 혼화재 종류별 온도 변화에 따른 시멘트 모르터의 응결 및 강도발현 특성

        주은희,손명수,차천수,황인성,김성수,한천구 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

        In this paper, setting and strength development of cement mortar are discussed under various mineral admixture content and curing temperature. Setting time exhibited an increasing tendency with an increase in curing temperature. Under low curing temperature, use of CKD resulted in a reduction in setting retarding, whereas FA and BS retarded the setting time of cement mortar. For compressive strength, high curing temperature and age leaded to an increase in compressive strength of concrete. Under low curing temperature, the use of CKD resulted in an enhancement of compressive strength at early stage, and exhibited a similar level of compressive strength with plain concrete. For this reason, use of CKD in cold weather concreting has positive effect on strength development at low curing temperature under early age.

      • Kim,Seong-soo : Possiblity of Low Salting Process in Gae-Woo Jeot(Salted and Fermented Gastrophoda) and Changes in Fatty Acid Composition during Fermntation 低鹽化 可能性 檢討 및 熱成중 脂肪酸 組成의 變化

        姜永周,河璡桓,金永東,宋大鎭,金洙賢,金成洙 제주대학교 1990 논문집 Vol.30 No.-

        To establish the way of processing of Gae-Woo jeot which used abalone intestine that has not been systematically used compare to its characteristic taste and fame as main ingredient and to develop as a local tourist good, the change of constituents the quality of salted fish products suring Gae-Woo jeot fermentation were examined. The results are as follows. 1. In the organoleptic test, Gae-Woo jeot which fermented through 65 days were dominant and the group of 105 salkt concentration were better than that of 20%. It was the best of 10% salted products to add small abalone. Both law salted(10%) and high salted (20%) Gae-Woo jeot were similar in general constityents, nutrients and texture. 2. Compositions of highly unsaturated acid were farely high to 45.6% and 46.1% in small abalone added froup and top sheel added group respectively. during 3 months fermentation low decreasing rate of 3~4% was shown. EPA(eicosapentaenoic acid) was approximately 7~8% and DHA(docosahexaenoic acid) was extremely low to be less than 0.3%. 3. In the changes General composition and pH, pH was within range of 4~5.5, 9~12% in protein, 3~5% in total sugar, 0.5~1% in lipid and approximately 1% in ash. 4. Gae-Woo jeot can be made with 10% low salting method, and 10% group gets all the better for taste, small abalone adding is recommended. 5. When low salt fermented fish of 10% is processed, it is highly recommended to put sorbitol, ethyl alcohol, lactic acid or other humectant for better taste and longer storage and good quality food additives must be developed for tourist and presently applied mil ordering transportation must be sought.

      • 대식세포의 Pro-inflammatory cytokine 생산에 대한 세포디짐의 효과

        주성수,강희철,원태준,황광우,이도익 중앙대학교 약학연구소 2003 약학 논총 Vol.17 No.-

        Cefodizime, a third cephalosporine, was originally developed for use in infectious disease as an advanced antibiotics. Cefodizime has also been known to play a meaningful role in activating natural killer properties of immune cells as well as enhancing immunological parameters such as phagocytosis. Furthermore, as the infection can result in remarkable changes for homeostatic mediators, it is expected that cefodizime may initiate the strong immuno- modualtory effect. In the present work, we investigated whether cefodizime has a biphasic effect of anti-bacteria and immunomodulation via macrophage. For the study, we isolated mouse peritoneal macrophages and treated with cefodizime 10㎍/㎖, 50㎍/㎖, 100㎍/㎖, IFN-v 10U/㎖.+LPS l㎍/㎖ Cells were then incubated for 4, 8, 12, and 24hrs to analysis the expression of IL-1, IL-6, IL-12 mRNA from macrophages. The results showed that cytokines were expressed more than that of control in a time-dependent manner and 100㎍/㎖ cefodizime group showed the greatest expression as much as the positive control (IFN-v+LPS)showed at 24h. In conclusion, cefodizime can play a significant role for the expression of pro-inflammatory cytokines, IL-1, IL-6, and IL-12 in earlier stage so that macrophages and other immune cells can response to the infectious substances, immediately. Moreover, when such pro-inflammatory cytokines are increased, we can also expect that the enhancement of cell-cell interaction of NK cell, CTL and B cell by cefodizime can affect the immunomodulatory effect along with its major role in anti-bacterial effect.

      • 혼화재 종류별 온도 변화에 따른 콘크리트의 응결 및 강도발현 특성

        주은희,손명수,차천수,한민철,김성수,한천구 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

        The objective the paper is to investigate the physical and mechanical properties of concrete incorporating mineral admixtures. For setting properties, at low curing temperature, setting time of concrete with mineral admixture is delayed compared with that of plain concrete. But, use of cement kiln dust(CKD) has a desirable effect on reducing setting retard under low curing temperature. For compressive strength, concrete with FA and BS have low strength at early stage compared with that of plain concrete under low curing temperature. However, the use of CKD resulted in an enhancement of compressive strength at early stage under low curing temperature, and exhibited a similar level of compressive strength with plain concrete. For this reason, use of CKD in cold weather concreting has positive effect on strength development at low curing temperature under early age.

      • 강진만 일차생산력의 계절변화

        주현수,김성호,이우범 한국환경생물학회 2002 환경생물 : 환경생물학회지 Vol.20 No.2

        강진만 해역의 6개 조사정점을 대상으로 1998년 2월부터 1998년 10월까지 계절별로 이화학적 환경요인과 일차생산력을 측정하였다. 일차생산력은 NaH^14CO_3을 이용한 배양방법을 사용하였고, 조사결과 2.78㎎Cm^-3Hr^-1의 범위를 나타났으며, 계절별 일차생산력의 변화는 하계, 동계, 추계의 순으로 나타났다. 조사정점별로는 강진만의 상류수역에 해당되는 정점 1과 2에 비해 3,4,5 및 6의 조사결과가 크게 나타났다. Chlorophyll a의 분포는 평균 5.16~17.90㎎m^-3를 나타났으며 계절별로는 하계에, 정점별로는 정점4에서 높게 나타났다. 일차 생산력과 Chlorophyll a 의 분포, 수중광도와는 정상관을, 부유물질과는 역상관을 보였으며 강진만의 일차생산력의 변화는 상류수역인 탐진강으로부터 유입되는 담수에 의해 크게 영향을 받고 있는 것으로 생각된다. The primary productivity and physicochemical factors were surveyed seasonally in Gangjin bay from February to October in 1998. The determination of the primary productivity was performed in situ be isotope-method using NaH^14CO_3. The range of primary productivity was 2.78 ㎎C m^-3 hr^-1∼4.92 ㎎C m^-3hr^-1 according to seasons. The primary productivity showed the highest value in summer, followed by those of winter, autumn and spring. The primary productivities of station 1, 2 which are located the upper area, were lower than those of station 3, 4, 5 and 6. The correlations showed that the primary productivity correlated with chlorophyll a, underwater light intensity but reversely correlated with suspended solids. These results suggested that the primary productivity in Gangjin Bay was mainly influenced by the inflow of freshwater from Tamjin River.

      • 국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

        이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

        Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

      • KCI등재후보

        포도알균 균혈증 환자에서 사망 예측 위험인자

        문수연,이미숙,손준성,이희주,이상오 대한감염학회 2008 감염과 화학요법 Vol.40 No.3

        Background : Staphylococcus aureus is a common cause of severe infection and frequently results in death or disability. We investigated potential risk factors influencing clinical outcome in S. aureus bacteremia (SAB). Materials and Methods : Our study is based on retrospective chart review for episodes of SAB from 168 patients, identified between January 2003 and December 2005. Twenty patients were excluded: 2 patients with infective endocarditis and 18 patients with metastatic lesions. Demographic, underlying diseases, sources of SAB, antimicrobial therapy, laboratory, and microbiologic characteristics were identified. Outcome was classified as death or survival 12 weeks after onset of SAB. Results : A total of 97 patients had survived and 51 patients died 12 weeks after the onset of SAB. Death group was older (66.4±13.6 vs. 59.4±14.9 years, P=0.007) and had higher Acute Physiology and Chronic Health Evaluation II system score (17.5±6.3 vs. 13.5±5.1, P<0.001) and the acute physiology score (11.1±5.5 vs. 8.0±4.3, P<0.001). Patients with nosocomial SAB (36 (70.6%) vs. 49 (50.5%), P=0.03] and ineradicable primary source of SAB (46 (90.2%) vs. 66 (68.0%), P=0.005] were more vulnerable to death. Multivariate analysis shows that hospital acquisition [adjusted odds ratio (OR)=2.93), ineradicable primary source (adjusted OR=5.74) and high APACHE II score (adjusted 0R=1.22) lead to higher mortality rate from SAB. Conclusion : Our study shows hospital acquisition, ineradicable primary source, and high APACHE II score are the risk factors related to death from SAB. On the other hand, methicillin resistance or initially ineffective antimicrobial therapy is not much correlated with mortality rate from SAB. 목적 : 황색포도알균은 중증 감염의 흔한 원인이며, 사망하거나 합병증이 발생하는 경우가 종종 있다. 본 연구를 통해 황색포도알균 균혈증 환자에서 임상적 결과에 영향을 미칠 수 있는 위험인자를 확인해 보고자 한다. 재료 및 방법 : 본 연구는 2003년 1월부터 2005년 12월까지 3년간 168 명의 환자에서 발생한 황색포도알균 균혈증에 대해 후향적 의무기록 조사를 바탕으로 이루어졌다. 성별, 나이, 기저 질환, 황색포도알균 균혈증의 원발 병소, 항생제 사용력과 미생물학적 특징에 대한 자료를 모았으며, 균혈증 발생 당시 질환의 중증도는 acute physiology score (APS)와 APACHE II 점수(acute physiology and conic health evaluation II system, APACHE II score)를 이용하여 측정하였다. 결과는 균혈증 발생 12 주 후 사망과 생존으로 나누어 분석하였다. 결과 : 황색포도알균 균혈증 발생 12 주 후 97명의 환자가 생존하였으며, 51명이 사망하였다. 사망 환자 군이 나이가 더 많았으며(66.4±13.6 vs. 59.5±14.9세, P=0.007), APACHE II 점수(17.5±6.3 vs. 13.5±5.1, P<0.001)와 APS (11.1±5.5 vs. 8.0±4.3, P<0.001)가 높았다. 병원 내 감염에 의한 황색포도알균 균혈증 환자[36 (70.62%) vs. 49 (50.5%), P=0.030]와 제거 불가능한 원발 병소를 지닌 경우[46 (90.2%) vs. 66 (68.0%), P=0.005] 사망위험성 이 높았다. 다 변량 분석에 의하면 병원 내 감염[adjusted odds ratio (OR)=2.93]과 제거 불가능한 원발 병소(adjusted OR=5.74), 높은 APACHE II 점수(adjusted 0R=1.22)에 의해 황색포도알균에 의한 사망률이 증가하였다 결론 : 본 연구에서 병원 내 감염과 제거 불가능한 원발 병소, 높은 APACHEH 점수가 황색포도알균 균혈증에 의한 사망과 관련된 위험인자이다. 반면, 메티실린 내성과 초기 부적절한 항생제 사용은 황색포도알균 균혈증의 사망률과 연관성이 없었다.

      • SCIESCOPUSKCI등재
      • 암센서용 TiO2/Au/CNT 나노복합물의 전기화학적 검출

        홍성미, 김홍일, 김한주, Wang, Xuemei, 박수길 충북대학교 건설기술연구소 2008 충북대학교 건설기술연구소 논문집 Vol.27 No.1

        Demand of rapid detection for cancer, it is necessary that high sensitivity, specificity, low cost, and simple method. CNT and metal nano materials are widely used to elecate efficient. CNT have various advantage, and can be composed with metal nano materials. Especially, Titanium oxide and gold nano particles are focused on sensor for detection of cancer, it can elecate electron transition feeiciency between electrode surface and target materials, and biological functionalization of CNT. It means that nano material is composed each other. In this study, electrodes are considered materialsd and their chracteristic for cancer sensor.

      • 섬진강 수계의 곡성군 어류상

        김성호,윤창호,주현수 한국환경생물학회 2002 환경생물 : 환경생물학회지 Vol.20 No.2

        섬진강 중류의 전남 곡성군 수계의 담수어류상과 서식현황을 2001년 3월부터 10월까지 조사한 결과,총 5과 22속 30종 1,786개체가 채집되었다. 출현한 어류는 26종이 잉어과 어류에 해당되었고, Rhinogobius brunneus의 1종만이 이차담수어에 해당되었다. 하천 전체에서 zacco platypus(우점도 24.2%)가 우점종으로 확인되었고, 아우점종은 Pungtungia herzi (10.7%)로 나타났다. 한국 고유종은 Rhodeus uyekii등 11종으로 전체 어류에 대하여 36.7%를 차지하여 비교적 높은 고유도를 나타냈다. 다양도 지수에 의하여 곡성군 섬진강 수계의 하천 수질오염을 판정한 결과,전체적으로 β-중부수성 수질상태 (다양도 2.70)를 나타냈으나, St.2와 St.3을 제외한 조사지역에서는 β-중부수성으로부터 중부수성까지의 하천수질상태를 나타냈다. The fauna of freshwater fish and the structure of fish community were investigated from March to October in 2001 at six stations in the middle reach of the Seomjin River, Gokseong-gun. The collected fishes (1,786 individuals) were identified into 30 species of 22 genera belonging to 5 families. Of them, cyprinid fish occupied 26 species, only one species (Rhinogobius brunneus) was secondary freshwater fish. Dominant species was Zacco platypus (dominance index: 24.2%) and subdominant species was Pungtungia herizi (10.7%). The endemic species of Korea were 11 species including Rhodeus uyekii (36.7%) about the ichthyofauna. In estimation of water quality by diversity indices, the general conditions of water quality of all survey times and all stations were relatively fine (β-mesosaprobic, diversity index: 2.70). But four survey sites except St. 2 and St. 3 showed severe water pollution with one or more times in total survey periods.

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