일반연제 발표 : 종양학 2, 일반부인과학 : 10년간 임신성 융모성질환의 임상적 고찰

주은희,김원규,박은동 대한산부인과학회 1995 대한산부인과학회 학술대회 Vol.76 No.-

학교에서 여성진로교육의 현황과 과제

주은희 연세대학교 여성연구소 1995 연세 여성연구 Vol.1 No.-

This study addresses the issues of career education for female students in Korea secondary and universities and identifies methods to assist students' career development. The study follows the triangulation method that included literature review, interview and administration of a dyadic grid that elicited costructs related to job attitudes of different groups. The subjects for this grid were 50 female university students and 50 male university students, 35 secondary school teachers, and 45 non-manual workers. Common constructs were obtained and compared between groups according to gender and occupation variables. The study includes seven major findings. First, female freshmen preferred the constructs related to self-assertion and appearance while male freshmen emphasized job and organization oriented constructs. Second, teacher and worker groups commonly chose the involvement in human relationship while teachers perceived “job-orientated women” as careless about their families. Third, in order, parents', students' and teachers' opinions were the major determinents in the choice of division in high school such as general vs vocational and the humanities and social science vs natural science. Fourth, students decided which major in the university to study during the last year of high school. Fifth, middle school female students were more dissatisfied with the career education in their schools than male students. They preferred extra-curricular activities to help them understand their aptitudes and interests. Sixth, sex-role stereotyping exists in the curriculum, school textbooks, and attitudes of secondary school teachers. Finally, a high rate of female students were not aware of the career education programs in their universities. However, they had a strong need for career education and legitimate expectations of career guidance by professors or professionals. The study concludes with three important points and recommendations for them. First, high school guidance efforts focus solely on entering universities and colleges while vocational school guidance efforts only emphasize entering the job world. Female students receive no integrated career guidance. Educators should offer vocational programs even in general high schools and provide various extra-curricular activities. Further, parents and citizens should establish programs to monitor the gender biases in educational practices. Second, cognitive gaps exist in constructs related to respect for career women between male and female students, parents, teachers and citizens should receive programs that narrow the gaps in career education. Finally, case studies of some schools showed that the administration in Korean secondary schools could lead career programs successfully. Therefore, the legitimate concerns of the educational administrators about career development for female students should be resolved.

90년대 전반기 패션디자인의 특성

주은희 이화여자대학교 대학원 1997 硏究論叢 Vol.32 No.-

대학사회에서의 성차별·성희롱 경험에 관한 조사

주은희 연세대학교 여성연구소 2000 연세 여성연구 Vol.6 No.-

비스테로이드성 소염진통제의 약물상호작용에 관한 연구

주은희,이령인,조행남,이용복,고익배 전남대학교 약품개발연구소 1997 약품개발연구지 Vol.6 No.1

According to the test increase of NSAID-uses, the possibility of the occurrence of drug interaction became increased. So we surveyed the drug interaction of NSAIDS in order to inhibit NSAID-related side defect. This study was accomplished for the NSAID-administered inpatients in Chonnam University Hospital at one day from Jan. to June in 1991. The NSAID-administered inpatients occupied 20.2% of total 3598 drug-administered inpatients On clinical department, orthopedic surgery occupied the highest value of 15.1% of NSAID-administered patient On the route of NSAID administration, injection occupied 32.7%, internal medicine 61.2%, external medicine 0.3% and the combination of injection & internal medicine 5.8%. On NSAID dosage form, injection occupied 38.5%. internal medicine 67% and external medicine 0.396. On the number of used NSAID, ale occupied 89.8%, two 9.2% arid three 1%. The average number of NSAID used by a patient was 1.1. The possible occurrence rate of drug interaction of NSAIDS was 33.1%. As the number of teed drug increased, the occurrence possibility of drug interaction of NSAIDS tended to increase. The possible occurrence rate of drug interaction of NSAIDS reached 100% in above 21 drug-used casts. The harmful interaction of NSAIDS could occur such as digitalis toxicity with digoxin in 3 cases, hypoglyocemia with antidiabetics in 8 cases, nephrotoxicity with diuretics in 57 cams, hemorrhage with anticoagulants or thrombolytics in 57 case, gastrointestinal hemorrhage with NSAIDS in 63 cases, the decease of antihypertensive effect with antihypertensives in 104 roses and the decrease of anti-inflammatory effect with antacids in 135 uses. So we should carefully monitor the drug interaction of NSAIDS and provide drug information to health team in order to prevent the harmful interaction of NSAIDS.

종합병원 외래환자 다제병용에 관한 실태조사

주은희,조행남,서세민,이용복,고익배 한국병원약사회 1997 병원약사회지 Vol.14 No.2

This study was accomplished to obtain the basic materials about polypharmacy-related drug interaction and side effect. The polypharmacy in relation to the route of drug administration, dosage form, clinical department and age was surveyed with the 1,632 outpatients in Chonnam University Hospital at one day of January, March and May in 1991. On the route of drug administration, internal medicine occupied 81.2%, the combination of internal medicine & external medicine 7.3%, external medicine 3.9%, injection 3.8% and the combination of internal medicine & injection 3.4%. On drug dosage form, internal medicine occupied 92.1%, injection 7.6% and external medicine 11.6%. The case to use 4 drugs occupied the highest value of 26.2% and the case to use 1 drug 8.4%. The highest number of used drug was 14 and 90% of the patients used less than 6 drugs. The average number of used drug per patient was 4.2. The average number of used drug in ophthalmological department was the lowest value of 2.4, in surgical department 4.4, in internal medical department 4.7 and in neurological department the highest value of 5.7. The average number of used drug in infants and pediatrics was 2.8, in 15-20 year old youth 3.6, in 21-60 year old adults 4.3 and in above 61 year old geriatrics 4.7. As age increased, the number of used drug tended to increase.

단백질 침전물이 소프트콘택트렌즈 함수율과 산소투과성 및 접촉각에 미치는 영향

주은희,성아영,오승진,이군자 대한시과학회 2010 대한시과학회지 Vol.12 No.4

목 적: 단백질 침전물이 콘택트렌즈의 함수율, 산소투과성 및 접촉각에 미치는 영향을 조사하였다. 방 법: Polymacon과 etafilcon A 재질의 소프트콘택트렌즈를 착용기간에 따라 수집하여 단백질 침전물을 추출하고 fluorometer를 이용하여 단백질 침전물을 정량하였다. 사용하지 않은 polymacon과 etafilcon A 콘택트렌즈를 lysozyme과 albumin 단백질이 포함된 인공눈물에 넣어 일정하게 단백질을 부착시키고 부착된 단백질 침전물을 정량한후 중량측정법, 전기분해 자동분석법 및 sessile drop 방법을 사용하여 함수율, 산소투과성 및 접촉각을 측정하여 대조군과 비교하였다. 결 과: Polymacon 재질의 콘택트렌즈에 부착된 단백질 침전물 양은 착용기간에 따라 차이가 없었으나, etafilcon A 재질의 콘택트렌즈는 착용기간에 따라 빠르게 증가하였다. 일정하게 단백질을 부착시킨 소프트 렌즈의 경우 함수율은 polymacon 렌즈와 etafilcon A 렌즈에서 모두 감소하였고, 산소투과성도 polymacon 렌즈와 etafilcon A 렌즈에서 모두 감소하였으며 접촉각은 polymacon 렌즈와 etafilcon A 렌즈에서 모두 증가하였다. 결 론: 소프트콘택트렌즈에 부착된 단백질 침전물은 렌즈의 함수율과 산소투과성을 저하시키고 접촉각을 증가시켜 콘택트렌즈 착용 시 불편감을 유발하는 원인이 될 수 있으며 특히 고함수 이온성 재질인 etafilcon A의 경우 더욱 문제가 될 것으로 사료된다. Purpose: To investigate the effect of protein deposit on the water content, oxygen transmissibility and contact angle of the contact lens. Methods: The polymacon and etafilcon A contact lenses were collected according to the wearing period, and protein deposits were extracted and measured by a fluorometer. Unused polymacon and etafilcon A contact lenses were incubated within an artificial tear solution containing lysozyme and albumin to allow to absorb the proteins on the contact lenses. The water content, oxygen transmissibility and contact angle were measured by gravimetric method, polarographic method and sessile method, respectively and compared with the control group. Results: The amount of protein deposits on polymacon lenses did not change according to the wearing period, however, there was a rapid increase in protein deposits on etafilcon A lenses. In the protein deposited lenses, the water content was decreased in both polymacon and etafilcon A lenses, the oxygen transmissibility was also decreased in both lenses, and the contact angle was increased in both lenses. Conclusions: Protein deposit on contact lens may cause discomfort when wearing them, because the deposit decrease water content and oxygen transmissibility, whilst increasing the contact angle of the lenses especially in high-water, ionic etafilcon A lens.

춘계학술대회 : 지상발표부 ; 가톨릭의대 : 맥관지방종 2예

주은희,김태윤,허원 대한피부과학회 1983 대한피부과학회 학술발표대회집 Vol.35 No.1

Dermovate NN^(�)의 임상적 효과

주은희,이강우,허원 최신의학사 1983 最新醫學 Vol.26 No.2

베나제프릴의 장관막 투과도와 흡수 클리어런스에 미치는 아목시실린의 영향

주은희,김영만,고형석,이용복,나한광 전남대학교 약품개발연구소 1998 약품개발연구지 Vol.7 No.1

Intestinal absorption of β-lactam antibiotics and angiotensin converting enzyme(ACE) inhibitors has been shown to use the carrier-mediated transport system. In vitro experiments have established that the efficacy of uptake by enterocytes depends on an inwardly directed proton gradient. It was suggested that benazepril was mediated by tripeptide transport system and that amoxicillin was transported by dipeptide transport carrier. The aim of this study is to assess the influence of amoxicillin on the intestinal absorption of benazepril using in vitro diffusion chamber and in situ single pass perfusion technique in the rat in order to elucidate whether the above transport systems are competitive or not. We obtained the gastrointestinal pemeability coefficient of amoxicillin, benazepril and both of them using in vitro diffusion chamber. And also the gastrointestinal absorption clearance of amoxicillin, benazepril and both of them using in situ single-pass perfusion method at steady state were calculated. Amoxicillin and benazepril were analyzed by HPLC. The results by the use of diffusion chamber in vitro indicated that the apparent intestinal permeability coefficient of benazepril was significantly(p$lt;0.01) decreased by amoxicillin(45.2%) and vice versa significantly(p$lt;0.01) decreased(89.1%). The results by the in situ gastrointestinal single-pass perfusion method indicated that the intestinal absorption clearance of benazepril was significantly(p$lt;0.05) decreased by amoxicillin (40.2%) and vice versa significantly(p$lt;0.05) decreased(54.8%). These results might suggest that they share the same peptide carrier pathway for oral absorption.