捻轉法이 竝行된 鍼刺戟 및 電鍼刺戟이 鎭痛效果에 미치는 影響

Park, Dong-Seok,Kim, Ji-Hoon,Min, Byung-Il,Oh, Soo-Myung 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Dong-Seok Park¹, Ji-Hoon Kim¹ and Byung-Il Min, Soo-Myung Oh,³¹Department of Acupuncture and Moxibustion, College of Medicine, ²Department of Physiology, College of Medicine, And ³East-West Medical Research Institute, Kyung Hee University,Seoul, Korea. Analgesic Effect of Manual Acupuncture and Electroacupuncture combined with Twirling Method. Proceeding of International Symposium on East-West Medicine Seoul. 187-200, 1999.-Twirling the needle (TN) is one of several needing methods frequently used for acupuncture in the oriental medicine. The present study was conducted to see if TN enhanced the antinociceptive effect produced by plain-or electroacupuncture in the rat tail flick test. Rats (Sprague-Dawley, 200-300g)lightly anesthetized with thiopental sodium(40mg/kg, i.p.) were used in the tail-flick test. The basal reaction time for tail-flick was 2 sec. For "plain" acupuncture(PA), a needle was inserted for 20 min into a Chock-samni (ST36) acupuncture point which (is located at the anterior tibial muscle and about 10mm below the knee joint). For electroacupuncture(EA), train-pulses(3 Hz,0.3-ms pulse width, 0.2-0.3mA) were applied to the inserted needle for the period of insertion. For combining TN with either PA or EA, TN was performed during the each acupuncture period. Two methods for TN were used; twirling 3 times for 1 second persisted for 1 min in every 5 mins(long-duration and long-interval;LDLI) and twirling 3 times for 1 second persisted for 10 sec in every 1 min(short-duration and short-interval;SDSI). PA and EA produced an increase in tail flick latency (TFL); peak increases were 21.3±5.1% and 42.1±17.3% of the pre-acupunture control, respectively, and occurred immediately after cessation of 20min-acupuncture. Performing TN combined with PA increased TFL more than PA itself by showing a greater peak increase in TFL when performed with a SDSI-TN than with a LDLI-TN(60.6±12.5% and 42.7±22.7% of the pre-acupuncture control, respectively). Performing TN combined with EA also increased TFL more than EA itself and a greater peak increase in TFL was observed with a SDSI-TN as compared to a LDLI-TN(77.5±13.8% and 67.3±14.0% of the pre-acupuncture control, respectively). These results indicate that TN enhances both PA-and EA-produced antinociception where an greater enhanced antinociception than a LDLI-TN. It is suggested that performing a SDSI-TN combined with EA seems to be one of the most effective ways to produce analgesia.

간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

Gilbert 증후군에서 열량 제한 시험과 Phenobarbital 자극 시험의 의의(14예)

이헌영,채경훈,정재훈,강윤세,김연수,문희석,박기오,이엄석,김선문,김석현,성재규,이병석,이강욱 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Gilbert 증후군은 인구의 7%에서까지 나타날 수 있는 매우 흔한 증후군으로서 비진행성인 양성의 만성적 경과를 치하며, 간질환의 증상과 징후가 없는 경한 비포합형 고빌리루빈혈증이 특징인 일종의 체질적인 증상으로서 혈장 빌리루빈 농도에 대한 사춘기의 영향 때문에 10대와 20대에 자주 진단이 된다. 따라서 임상적인 중요성은 미약하지만 높은 빈도가 예상되는 점에 그 중요성이 부여되어야 할 것이다. 따라서 적정한 임상적 진단법으로 기왕에 소개된 열량제한 시험과 phenobarbital 유도 시험을 시행하고 이들의 진단적 가치를 알아보기 위하여 본 연구를 시행하였다. 1990년 7월부터 1999년 4월까지 충남대학교병원에 내원하여 HBsAg, IgG anti-HBc 및 anti-HCV가 음성이고, 간 초음파 스캔에서 이상이 없으며, 혈청 AST, ALT 및 AP가 정상인 비음주자에서 경한 비포합형 고빌리루빈혈증이 있는 14예의 환자들을 대상으로 ^(99m)Tc-DISID 스캔을 시행하였으며, 기저 치 총빌리루빈 및 포합형 빌리루빈 치를 측정한 다음에 하루에 400Kcal로 48시간동안 제한한 열량 제한 시험을 시행하였고, phenobarbital을 하루 60mg씩 5일간 투여한 후에도 각각 총빌리루빈과 포합형 빌리루빈 치를 검사하여 비포합형을 구하였다. 대상 환자들은 모두 14예로서 남자가 11예(78.6%)였고 여자가 3예(21.4%)여서 3.7:1로 남자에서 많았으며, 20대가 6예(42.9%), 30대가 역시 6예(42.9%) 및 40대가 2예(14.2%)로서 2,30대가 대부분(85.8%)이었다. 열량 제한 시험 후의 총빌리루빈 치, 비포합형 및 포합형 빌리루빈 치들은 평균 각각 5.5±2.7, 4.2±2.3 및 1.3±10mg/dL 로서, 시험 전 치들인 3.0±0.8, 2.2±0.8 및 0.7±0.4mg/dL 보다 유의하게(p=0.001, p=0.001, p=0.023) 상승하였다. 포합형 빌리루빈 치도 유의하게 상승하였으나 비포합형의 상승보다는 훨씬 낮아서 주로 비포합형이 증가하였다. phenobarbital 투여 중 설사가 발생하여 중단한 1예를 제외한 13예에서 열량 제한 시험 후에 상승하였던 총, 비포합형 및 포합형 빌리루빈 치가 phenobarbital 유도 시험후에는 2.0±1.1, 1.5±0.8 및 0.5±0.4mg/dL로서 열량 제한 시험 결과보다 유의하게 낮아졌고(p=0.00, p=0.000, p=0.001), 열량 제한 시험 전의 기초치들인 3.0±0.8, 2.2±0.8 및 0.7±0.4mg.dL 보다도 더욱 낮아졌으며 유의한 차이(p=0.001, p=0.02, p=0.005)를 나타내었다. 14예에서 시행한 ^(99m)-Tc DISIDA 스캔에서 9예(64.3%)가 정상이었고, 5예(35.7%)에서는 심장 및 신장으로의 간외 섭취가 3예였고, 60분까지 소장 배출이 없는 배설 지연 예와 담낭 수축 불량 예가 각각 1예 씩 발견되었다. Phenobarbital 투여시험에서 민감도가 열량제한시험에 비해 더 높았다(92.3%와 50.0%). Gilbert 증후군에서 1일 400 Kcal로 48시간의 열량제한 시험과 1일 60mg의 phenobarbital을 5일간 투여하는 유도 시험은 편리하고 유용한 임상적인 진단법으로 이용할 수 있다고 생각된다. 그러나 열량 제한 시험에서는 증가 기준의 통일이 필요하다고 유추되며 phenobarbital 유도 시험이 민감도가 더 높은 것으로 생각된다. Gilbert's syndrome is very frequent and benign chronic process characterized by mild, intermittent, unconjugated hyperbilirubinemia without any symptom and sign of liver disease. Previously intoduced caloric restriction test and phenobarbital stimulation test as two appropriate clinical tests had been examined and their diagnostic values were reevaluated. Fourteen patients with mild, persistent, unconjugated hyperbilirubinemia were included. Subsequently caloric restriction has been applicated by 400 Kcal/day for 48 hours and phenobarbital has been prescribed by 60 mg/day for 5 days. Therafter serum levels of total and direct bilirubin were measured. Most of the patients were third and fourth decade(85.8%) and male predominant. Each basal serum levels of total, indirect and direct bilirubin were 3.0±0.8, 2.2±0.8 and 0.7±0.4 mg/dL. After caloric restriction test, each levels were increased significantly to 5.5±2.7, 4.2±2.3 and 1.3±1.0 mg/dL(p=0.001, p=0.001, p=0.023). After phenobarbital stimulation test for 13 patients had been practiced, increased levels of each bilirubin after caloric restriction test were decreased significantly to 2.0±1.0, 1.5±0.8 and 0.5±0.4 mg/dL(p=0.000, p=0.000, p=0.001) and these levels were significantly lower than basal levels(p=0.001, p=0.02, p=0.005). The sensitivities of caloric restriction test were 85.7%, 50.0%, and 71.4%, 35.7%(1.0, 1.5 mg increase of total bilirubin and 1.0, 1.5 mg/dL increase of indirect bilirubin). The sensitivities of phenobarbital stimulation test were 93.2% and 92.3% at criteria of 1.5 mg/dL increase of total bilirubin and indirect bilirubin. On the diagnosis of Gilbert syndrome, caloric restriction test and phenobarbital stimulation test are convenient and useful diagnostic tools in clinical face. And also phenobarbital stimulation test has higher sensitivity than caloric restriction test. Furthermore, standardization of bilirubin increment would be necessary in caloric restriction test.

연폭로 수준에 의한 공기중 연농도와 혈액중 연농도간의 상관성

박석건,김광종,장성훈 大韓産業醫學會 1991 대한직업환경의학회지 Vol.3 No.1

The correlation between the lead concentration in air at work site and in blood among three different groups of workers was studied. The test subjects were 50 lead solderers in an eleotronic company(Group 1). 66 lead smelters(Group 2). 40 workers in storage battery factory(Group 3). The results were as follows: 1. The geometric mean of air lead concentration in Group 3 was the highest level among the three groups at 0.226 mg/㎥ (0.070-1.475 mg/㎥). The lead concentrations at work sites were found to be significantly different among, the three groups. 2. The mean of blood of lead concentration in Group 3 was 74.3 ㎍/dl(17.0-149.3 ㎍/dl) was also the highest level among the three groups. The levels of lead concentration among the three groups were significantly different. 3. In Group 2 and 3, the correlation coefficient between lead concentration in air and in blood was statistically significant. The correlation coeffioient was found to increase with the level of lead exposure.

대학생 축구선수의 등속성 체간근력과 대퇴근력 및 거퇴근력과의 관련성

박기용,홍석민,최경훈,추근도 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

The purpose of this study was to investigate the relationships among trunk muscle, knee, and ankle strengths using Cybex770, the isokinetic muscle functioning measurement device. 41 K and Y University soccer players who did not have any experience about back pain or spine surgery were recruited as subjects. The results of the study were as follows. 1. Trunk extension was significantly higher than trunk flexion and muscle strength was diminished with increasing load speed. 2. Trunk flexion/extension ratio was well balanced at 30。/sec but this balance was broken with increasing load speed. 3. At 60。/sec of load speed, the knee extension and flexion of the left side were higher than those of the right side. 4. At 60。/sec of load speed, the ipsilateral muscle strengths of the left knee were well balanced but those of the right side were imbalanced. 5. At 60。/sec of load spped, the ratio of bilateral muscle strength of knee was -18.5±32.3% and this implies the possibility of knee injury. 6. Plantalflexion and dorsiflexion of the right ankle were higher than those of the left side, and dorsiflexion/plantalflexion ratio of the left side was higher than that of the right side. 7. The ratio of bilateral muscle strength of ankle at 60。/sec of load speed represented a balanced muscle development but this balance was broken with increasing load speed.8. There were partially significant relationships between trunk muscle and knee strengths. and between knee and ankle strengths. In conclusion, the trunk muscle strength of soccer player might be a very important factor to improve performance. In addition. a training technique which considering strength and speed is needed to develop not static but dynamic strength. This training not only develops well balanced muscle strength but also protects sport injury. Thus, the isokinetic training of trunk could improve the trunk muscle strength. and increase the ability of flexion/extension of knee and ankle.

抗打應力을 考慮한 말뚝과 해머의 組合

박용원,김석훈 명지대학교 공학기술연구소 1993 공학기술연구소 논문집 Vol.8 No.-

In pile driving practice, driving hammer should match well with piles in order to avoid pile dammage due to overdriving or imperfect penetration from insufficient hammer capacity. Some pile-hammer couples recommended in handbooks and manuals are used in pile driving. However, they have not been examined with driving stress and allowable stress of pile in driving practice at field. This study performs calculation of driving stress with wave equation analysis program(WEAP/G) and several pile driving formulae for PC and PHC piles. In calculation, the input data are made to represents the practical conditions at field. As results we recommend pile-hammer couples for PC and PHC piles with diesel hammers. The driving stresses calculated with pile driving formulae show tremendous scatter and therefore using pile driving formulae in driving stress calculation is not recommendable.

볼레로시스템의 運用上 法的 爭點에 관한 硏究

박석재,신건훈 한국해운학회 2001 해운물류연구 Vol.33 No.-

The bolero system represents a technical and legal infrastructure to facilitate paperless trade in goods via the Internet. It is operated by Bolero International Limited, a joint venture between SWIFT and TT Club. Bolero provides a solution to the security issue of dealing via the Internet by providing for message integrity, authenticity and non-repudiation via a messaging system(Core Messaging Platform or CMP) based on public key cryptography with Bolero acting as the certification authority. The contractual structure of Bolero is based on Bolero Rulebook which is a multilateral contract between each user of the Bolero system and every other user and seeks to create a legal background for Bolero. There are certain legal issues in relation to the operation of Bolero system. The object of this article examines the basic legal issues in relation to the operation of Bolero system. The legal issues are as following : ·Legal requirements for writing in relation to contracts formed through Bolero system ·The transfer of the right to goods in transit ·The admissibility of electronic evidence ·Choice of law and jurisdiction for Bolero Rulebook

전기설비에서의 고조파 영향분석과 저감대책에 관한 연구

박석훈,유인근 창원대학교 산업기술연구소 2001 産技硏論文集 Vol.15 No.-

In recent years there has been an increasing usage of switching devices such as SCR, IGBT, Power TR and etc, in home appliances and industrial machinery. A lot of harmonics are generated through the switching processes, which cause considerable harmonic distortion in the network and may result severe damages to the precise power equipments. This work presents the performance characteristic of digital watt-hour meter under the harmonics of voltage and current. Each waveform involved is different in magnitude, phase, and THD(Total Harmonic Distortion). It is possible to generate harmonics and control those waveforms using RTDS. Tests were performed on a selected sample of three-phase digital watt-hour meter which is coupled with data acquisition system via RS 485/232 converter. The percentage error rate of the watt-hour meter is compared for both sinusoidal and non-sinusoidal cases and the results are given. This paper also deals with observations of events that occur in the Dimmer circuits and phase control which could affect harmonics problem to the commercial power system. In order to reduce the effect of harmonics and design filters, Solid State Relay Dimmer(SCRs or TRIACs) and Noise Filter are described, and the effects of harmonics is also analyzed.

PC12세포에서 Reserpine에 의한 Preproenkephalin 유전자 발현의 조절

박석호,임동윤,최철희,김상훈,박상학,김학렬 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.1

In cultured PCl2 celIs, prepronkephalin gene expression was studied by measuring preproenkephalin mRNA levels as well as enkephalin content after the treatment of reserpine. Reserpine(0.5 uM) elicited and increased enkephalin peptide levels within 6-24 hrs, which was not inhibited by cycloheximide(2ug /ml), a protein synthesis inhibitor. In addition, reserpine-induced increase of enkephalin was not inhinited by dactinomycin(5ug / ml), which was found to decrease preproenkephalin mRNA. When preproenkephalin mRNA was measured by Northern blot hybridization with cDNA probe, reserpine elicited a slightly increased preproenkephalin mRNA in PCl2 cells as well as in the rat adrenal glands. From the present experimental data it is thought that reserpine-induced enhancement of cellular enkephalin content in cultured PCl2 cells may be mediated through the post translational processing along with a slightly increased transcription.

에타놀 정맥투여 고양이의 뇌압 변화에 관한 연구

김세훈,장석종,박해근 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

It has been well known that respiratory status has affected the intracranial pressure by' changing the brain blood flow, and also ethanol has affected the respiratory system by inhibiting the respiratory center and has affected cardiovascular system by inhibiting the cardiac performance and decreasing the total peripheral resistance. However, effect of ethanol on intracranial pressure has not been studied satisfactorily. Thus, following experiment was performed to examine the change of the intracranial pressure after ethanol administration in the cats. Ethanol was infused intravenously by lg ethanol per kg body weight for 15 minutes. Intracranial pressure was measured through balloon inserted between epidura and skull. Arterial blood pH, Po_2, Pco_2, ethanol concentration were measured. The results obtained are surnmerized as follows. Blood ethanol concentration increased by linear and peaked at 15 minutes(blood ethanol concentration was 409±31 mg%). Po_2, Pco_2. and pH at 15 minutes were 80. 3±5. lmmHg, 49.2±3.3mmHg and 7.24 =0.015 respectively. Blood pressure began to decrease and arterial pulse pressure began to increase at 10 minutes and more and more at 15 minutes respectively. Intracranial pressure began to increase at 10 minutes (blood ethanol concentration was 316±33 mg%) and peaked as 168.7±11.4% contrast to control at 15 minutes and also amplitude of intracranial pulse wave was increased. From the above results, it was suggested that intracranial presssure and amplitude of intracranial pulse wave were increased significantly by inhibiting respiratory center and thereby dilatating cerebral blood vessels with intravenous ethanol administration.