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      • 청주대학교 간호학과 교육과정 개발 연구

        안경주 김철규 전해옥 김봉정 김혜숙 채명옥 윤현정 한달롱 김아린 청주대학교 보건의료과학연구소 2014 보건의료과학연구 Vol.3 No.1

        Dynamics in the workplace and in society have contributed to the paradigm shift to outcome-based education. This study was performed to develop the curriculum based on assessment of existing program for the baccalaureate nursing program at Cheongju University. We used three steps-Analysis, Design, and Development-in ADDIE model for developing curriculum. The subjects were 18 graduate nurses, 41 nursing students, 38 parents, and 2 nursing team leaders for analysis of core competence. In conclusion, developing an outcome-based curriculum might be used to facilitate the students' development and evaluate the competence of the student during and on completion of the nursing baccalaureate program at Cheongju University.

      • 항갑상선제로 치료한 그레이브스병 환자의 관해예측인자

        남일송,윤여일,김선규,김용현,이주영,목지오,윤석기,김철희,김영선,변동원,서교일,유명희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

        Background: Most cases of Graves' disease have been treated by antithyroid drugs in Korea. The major drawbacks of antithyroid drugs are the relative high rate of relapse and the inconvinience of long term therapy. Measurement of TBII and TRH stimulation test have been considered as the most reliable tests predicting relapse, but the predictive power is not high enough to use in clinical situation. This study was performed to find good prognostic indicators in Graves' disease patients after the discontinuation of antithyroid drug therapy. Subjects and methods : We restrospectively evaluated 96 patients with Graves' disease who showed normal TRH test at the end of antithyroid drug therapy and were followed for more than one year. Serum T3, T4, T3/T4 ratio, TBII, Anti-TPO Ab and TGAb levels were measured at the time of diagnosis and at the end of therapy. Two to three months after withdrawal of antithyroid medication, serum TSH and free T3 responses to TRH were examined. These parameters were compared between the relapse group and the remission group. Results : Among the 96 patients, 22 patients(22.9%) relapsed(Group Ⅱ) and 74 patients(77.1%) remained in remmision(Group Ⅰ). No significant difference was observed between the relapse and the remission group in clinical parameters, serum T3, T4, TSH, T3/T4 ratio, TBⅡ and Anti-TPO Ab determined before and after treatment. Serum TSH and free T3 levels measured after TRH stimulation were also similar in both groups. Serum TGAb levels determined at the end of treatment were significantly higher in the remission group(p<0.05). Relapse following the discontinuation of therapy occured within 24 months in 72.7% of the relapsed cases. After 24 months, relapse rate was reduced significantly. Conclusion : These results suggest that high serum TGAb levels could be a favorable prognostic indicator for the long term remission of Graves' disease treated with antithyroid drugs, and may suggest that Hashimoto's thyroiditis is combined with Graves' disease in those patients.

      • KCI등재
      • 식이 상태와 카페인 투여가 일회적 운동 시 흰쥐 가자미근의 제 4형 당수송체에 미치는 영향

        김광찬,김종오,오명진,윤재석,서태범,윤진환,정일규 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

        The purpose of this study was to evaluate the effects of diet condition and caffeine ingestion prior to long distance treadmill running on the GLUT-4 protein expression in Sprague-Dawley rats' soleus muscle. Total is rats were used For subjects and assigned to six groups: Fasting control(FaC group), feeding control(FeC), asting+exercise(FaE), feeding +exercise(FeE), Fasting +caffeine+exercise(FaCE), and Feeding+caffeine+exercise(FeCE). Each animal belongs to fasting group was forced to be in fasting state at least for 14 hours, The food was provided to each rat in feeding group 12minutes prior to treadmill running and the caffeine was ingested through the stainless steel tube 60minutes prior to exercise. All rats in exercise groups were forced to perform treadmill running for B9 minutes at the speed of 18m/min, and 0%grade, immediately after exercise, all animal was anesthetized by Chlorofolm (DC Chemical, Co, Ltd) and about 10ml of blood was drawn from each animal's heart and than soleus muscle was exposed and separated from the rat's leg. we found that the GLUT-4 in feeding groups increased much significantly compared to fasting groups(p<.05). The exercise in fasting state appeared to suppress the expression of GLUT-4 protein different from the exercise in feeding state. Cafreine ingestion prior to treadmill running of 60 minutes induced the significant increase or GLUT-4 protein expression both in fasting or feeding states.

      • 地方公共財가 都市住民의 住居移動 및 住宅價格에 미치는 影響에 관한 實證硏究 : 특히 서울市의 學群을 中心으로 with Special Reference to School Districts of Seoul

        金英模,宋明圭 단국대학교 1990 論文集 Vol.24 No.-

        The primary purpose of this study is to investigate the efforts of local public goods on intra-city migration and on housing price with special reference to high-school education quality of eight school districts of Seoul. The analysis of the effects on intra-city migration is based on the attitude survey of the city residents which was performed for this study during December, 1989. The survey contains three major inquiries. The first inquiry is concerned with the residents' past intra-city migration experiences and migration motives. The second inquiry is connected with the motives of present residential choice. And, the third inquiry is related to the most desirable neighbourhood. The survey results are summarized as the followings. The primary motive of intra-city migration is not dissatisfaction with local public goods of old residency but other economic one. But, the main incentive of the present residential choice is proved to be high quality of local public goods including high-school education of the present community. And, the most desirable neighbourhood turns out to be the one which is equiped with high quality local public goods, especially, good traffic facilities, high level of public safety, clean air, low noise, and high quality of high-school education, too. The effects on housing price are analyzed through various statistical regression equations which contain housing price as the dependent variable and housing size, construction year, house style, accesibility to CBD, and the quality of various local public goods including park, traffic facilities such as road and subway, public safety, population density, and high-school education quality as the independent variables. The results of analysis reveal followings housing price. But, various local public goods, especially, high-school education quality, public safety, and subway facilities are proved to have significant and, according to circumstances, strong effects on housing price.

      • 빌트인 모터를 이용한 2축 제어 미세 가공기 개발

        김건희,김효식,양순철,이상용,국명호,이선규,김윤중,홍권희 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

        This paper describes development of low cost precision machine that has combined the Build-in Motor with a vacuum chuck. This study mainly aims to find out a cutting condition for maintaining optimum surface condition and to examine cutting characteristics of the precision machine that is equipped by diamond bites. The cutting materials is Al alloy. Several experiments were carried out to find out the main factors that affect the surface roughness such as principal axis RPM(rotation per minute), feeding speed, and cutting depth. As a result, we obtain The optimum cutting condition of the developed precision machine.

      • 뼈대구조물의 형상최적화에 관한 연구

        김주명,이진원,이규원 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2002 工學硏究 Vol.33 No.-

        The conventional design process depends on the designer's institution, experience, and skill. With recent advances in computer technology, it is possible that the structural optimization is to decide sizes and shape of various parts of the structure to meet performance requirements. So, the engineers are attracted by the optimum design, which is to select optimal values of the design variables such that the objective function is minimized and constraint are satisfied. Until now, the studies of optimization are classified the member sizing optimization, shape optimization, and optimization of topology. The shape optimization can improve the effectively objective function. But since the configuration variables contain size variables, it is very complex and requires a long time to select optimum solution. The research of effective shape optimization is demanded promptly. The purpose of the paper is to develop the shape optimization of the framed structures.

      • KCI등재

        慢性 精神分裂症에서 Penfluridol이 血淸 Prolactin値에 미치는 影響

        金明珪 大韓神經精神醫學會 1986 신경정신의학 Vol.25 No.2

        The experiment was aimed to study the prolactin response induced by long acting oral antipsychotics, penfluridol in 17male chronic schizophrenics. After one week wash out period of other neuroleptics, penfluridol was administered orally with increment of 20mg per week, and serum prolactin level was measured by the method of radioimmunoassay at the interval of 1, 2, 3, 4, 5, and 6 weeks after administration of penfluridol. The results are as follows: 1)After one week washout period of other neuroleplics, the mean serum prolactin level was measured as 13.9±8.57ng/ml. 2)The mean serum prolactin levels after administration of 20mg, 40mg, and 60mg of penfluridol were 24.3±11.89ng/ml, 38.1±20.66ng/ml, and 56.1±25.47ng/ml respectively. These rapid increases of prolactin secretion were statistically significant(P<0.005). 3)The mean serum prolactin levels after administration of 80mg and 100mg of penfluridol were 63.9±27.45ng/ml and 69.4±29.83ng/ml respectively. These increases showed less higher increases than those of administration of 20 to 60mg of penfluridol. ridol. 4)The clinical symptoms were slightly improved, but those were not as much as increase of serum prolactin levels. As the above results, it was known that the penfluridol was effected serum prolactin levels for 1 week.

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