치근면에 항균 varnish 처치 전후의 치태 세균 및 치은열구액내 항체수준 변화에 관한 연구

권혁춘,도정욱 大韓齒科保存學會 1993 Restorative Dentistry & Endodontics Vol.18 No.2

In the prevention of root surface caries, antimicrobial therapy for the control of subgingival and supragingival plaque is seriously considered as a long term suppression of pathogenic microflora. Recently, varnishes containing antimicrobial agents have been developed to control the supragingival mocroflora. The purpose of this study was to determine the antimicrobial effects of 20% chlorhexidine varnish and 2.6% silane fouoride varnish with sealant. In clinical experiments, 12 subjects were selected from the periodontally treated patient and divided into 3 groups. after a dental prophylaxis, the subjects were treated with single application of placebo varnish(group 1), 20% cholrhexidine varnish(group II), and 2.6% silane fluoride varnish(group III). Root surface plaque samples were taken before(baseline)and one, two, four, and 8 weeks after the treatments. Microbiological examinations of root surface plaque were performed with culture study and indirect immunoflorescence(I.I.F) study, and immunological examination of gingival crevicular fluid antibody titers was performed with ELISA study. The results were as follows : 1. Pathogenic microflora on the root surface including S. murans, S. sanguis, s. mitis, A. naeslundii, A. viscosus were 24-37% on I.I.F. study. 2. S. mutans, S. sanguis, S. mitis, A. measlundii, A. viscosus of the root surface plaque was significantly reduced from I week to 8 weeks after antimicrobial varnish treatment, but showed generally increasing tendency in control group. 3. Gingival crevicular fluid antibody titers were significantly reduced from 1 or 2 weeks to 4 weeks after antimicrobial varnish treatment.

Quinlolone 유도체 국소도포에 의한 좌창치료의 임상적 연구

권철욱,노영석,김재홍,조소연,강형철,함정희 大韓臨床藥理學會 1994 臨床藥理學會誌 Vol.2 No.2

삼일열 말라리아에 합병된 비장 파열 1예

홍경욱,이정아,김원진,박철민,권혜리,박혜원,엄중식 대한감염학회 2007 감염과 화학요법 Vol.39 No.5

국내의 토착형 말라리아는 삼일열 말라리아로, 1993년부터 재유행이 시작되었다. 말라리아의 중요한 합병증으로 드물지만 비장 파열이 있는데, 이는 주로 삼일열 말라리아에 의해서 발생되며, 국내에서는 1999년 말라리아에 의한 비장 파열로 비장 절제술을 시행한 예가 보고된 바 있다. 현재까지는 비장 파열이 있을 때 비장 절제술이 일차적인 치료로 되어 있으나, 비장 절제술 후의 감염 위험성이 크므로, 활력 징후가 불안정하거나, 출혈이 지속되는 소견이 보이지 않으면 가급적 보존적 치료를 하는 것이 추천된다. 저자들은 비장 파열이 동반된 말라리아 환자에서 비장 절제술을 시행하지 않고 보존적 치료로 호전된 예를 경험하여 보고하는 바이다. Plasmodium vivax has been the predominant Plasmodium species in the Republic of Korea and reemerged in 1993. Spontaneous rupture of malarial spleen is a rare but important complication associated with P. vivax infection. Only one case of spontaneous rupture of malarial spleen was reported in Korea in 1999. Splenectomy is still accepted as the treatment of choice in cases of spontaneous rupture of the spleen. But, considering increased risk of postsplenectomy infecion, splenectomy should be reserved for those patients with severe rupture or those with continued or recurrent bleeding. And conservative treatment should be considered in selected, closely monitored patients. We report a patient with P. vivax malaria who developed a spontaneous splenic rupture and was improved by conservative treatment.

포스트-텐션 프리캐스트 외부 넓은 보-기둥 접합부의 비탄성 거동

박상욱,최윤철,김영찬,김대중,임재형,권기혁,문정호,이리형 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

Experimental results from the cycle lateral load tests for post-tensioned precast wide beam-column connections were presented. Six exterior beam-column assemblages of half scale were tested in the laboratory. The specimens consist of U-shaped precast wide beams and concrete columns. The continuity at the beam-column joint is achieved with the topping concrete and post-tensioning. The specimens were designed with parameters of the beam-to-column depth ration and the number of tendons within column core. The test results showed that the post-tensioned precast wide beam-column connection satisfied the provisional standard by ACI of acceptance criteria for concrete special moment frames.

고층사무소건물의 매스구성을 위한 전문가 시스템의 개발에 관한 연구

서정훈,박상현,권종욱 영남대학교 환경문제연구소 2000 環境硏究 Vol.20 No.1

건축에서의 전문가 시스템은 설계자에게 많은 가상적인 해결안을 반복해서 수집해야할 수고를 줄여주고 모델링이나 정보제공과 같은 정형적인 측면과 설계의 판단, 상황별 특성과 같은 비정형적인 측면을 연결시키는 도구로 작용한다. 본 연구는 고층사무소건물의 설계과정 중 매스 구성 단계에서 중요한 역할을 하는 요소를 찾아내고, 그 요소들의 정형화 및 표준화 작업을 통해 고층사무소건물의 매스구성을 보조하는 전문가 시스템을 개발하는데 그 목적을 두었다. 본 연구에서 얻어진 결론을 요약해보면 다음과 같다. 건축설계작업 중 매스구성 단계를 제한조건을 만족시켜나가는 제한조건 만족모델로 인식할 수 있었으며, 이 제한조건의 일부를 체계화하여 건물의 매스구성을 보조할 수 있는 시스템을 개발하는 것이 가능하였다. 또, 개발된 시스템을 실제 사례를 통해 평가해 본 결과 타당성 있는 결과물을 산출할 수 있었다. In architecture, the expert system helps architects reduce unnecessarily repeated process. It also serves as a tool of linking patterned processes such as medeling and information provision, with unpatterned processes like decision-making process which can produce different results depending on the situation. This study is devoted to develop an expert system which is helpful to find out the important factors in massing process and to assist the massing of high-rise office buildings through patternization and standardization. The conclusion from the study as follows; It is definitely possible to make the expert system recognize the massing process as a process of meeting all the constraints on a step-by-step basis. So, the developed expert system can assist the massing process by systemizing parts of the constraints. It also proved that the developed knowledge-based system can produce proper outputs as its test showed during the study.

경남 창녕지역 절취사면의 붕괴 및 보강대책에 관한 사례연구

박춘식,장정욱,이진권 국립7개대학공동논문집간행위원회 2005 공업기술연구 Vol.5 No.-

1) The objective of this study is to acquire stabilization of collapse of cut-slope in Chang-Nyung, Gyeong-Nam. The following shows the results of this study. 2) We applied a reinforcement method with the latticed beam (0.50X0.50) + permanent anchor (PC 6XΦ12.7mm, Ta = 50.0t/EA, etc 3.0m), and fill gravels(D=35cm) in the latticed beam. 3) We attenuated the slope (1:20.), and stabilized the slope pace by ASANA method. 4) We planned a drainage way(U-type, 0.40X0.40) in order to prevent surface water from inflowing into underground.

필라델피아 염색체 양성 급성골수성백혈병에서 Imatinib Mesylate로 분자학적 관해를 유도한 후 성공적인 자가 말초혈액 조혈모세포이식이 시행되었던 1예

김여경,이제중,이병환,변정래,조덕,이일권,정익주,양동욱,김형준 대한조혈모세포이식학회 2003 대한조혈모세포이식학회지 Vol.8 No.1

저자들은 필라델피아 염색체 양성 급성골수성백혈병 환자에서 복합항암화학요법으로 혈액학적 완전관해를 유도하고, imatinib mesylate를 이용하여 분자학적 관해를 유도한 후, 성공적으로 자가 말초혈액조혈모세포이식을 시행하였던 1예를 경험하였기에 이를 보고하는 바이다. Philadelphia chromosome (Ph¹)-positive acute myeloid leukemia (AML) is very rare disease, comprising 3~4% of the AML, and is a clinically distinct entity with poor clinical outcome with conventional chemotherapy. We report a case of Ph¹-positive AML who underwent successful autologous peripheral blood stem cell transplantation after achieving a molecular remission with imatinib mesylate.

감광제/광촉매에 의한 공기오염물질 제거

이재구,안기창,박주형,권정욱 충북대학교 첨단원예기술개발연구센터 1999 연구보고서 Vol.4 No.-

일반 주거환경 또는 재배시설 내의 공기오염물질인 농약 및 병원성 미생물을 인위적으로 제거하기 위해서 자연광 또는 인공광 조건하에서 몇몇 감광제/광촉매에 의한 광분해 촉진효과와 미생물의 살균효과 시험을 수행하였다. 광촉매로는 반도체 물질인 PC-1과 PC-2, 그리고 산화제로 사용되는 PC-3, PC-4, PC-5 및 PC-6과 감광제로 PS-7과 PS-8을 선발하였다. 그리고 시험화합물로는 유기인계 살충제인 dichlorvos와 dicarboximide계 살균제인 procymidone, 환경오염물질인 methyl tert-butyl ether (MTBE)를 선정하였고, 유해 미생물로는 Pseudomonas putida, Phytophthora capsici, Salmonella typhimurium, 및 Escherichia coli를 선정하였다. Dichlorvos의 경우에는 자연광과 인공광 조건하에서, 광촉매 무처리구에 비해 각각의 광촉매가 처리된 모든 처리구에서 4배 이상의 광분해 촉진효과를 보였으나, MTBE의 경우에는 단지 광촉매 PC-1 처리구만 이 광촉매 무처리구에 비해 약 17배 이상의 분해 촉진효과를 보였다. 또한 procymidone의 경우에도 PC-1, PC-6 및 PS-8에 의한 광분해가 약 3배 이상 촉진되었다. 공기 중의 미생물을 제거하기 위한 예비시험에서는 미생물 현탁액에 PC-1을 첨가하고 인공광을 조사함으로서 미생물의 생육이 저해됨을 확인할 수 있었다. 또한 평판배지에 도말된 Salmonella typhimurium은 광촉매 PC-1의 주변에서 미생물 생육이 저해됨을 보였다. 이상의 결과에서 볼 때, 광조건 하에서 이러한 감광제/광촉매를 이용한 기술은 농약을 비롯한 여러 환경 오염물질을 제거하여 재배시설 내의 작업자와 일반 대중의 환경오염원에 대한 노출을 예방할 수 있을 것으로 기대된다. For the artificial removal of the air pollutants such as pesticides, environmental toxicants, and pathogenic microorganisms in the greenhouse or the living environment, the accelerated photodegradation and the biocidal effects by some photosensitizers (PS)/photocatalysts (PC) were tested under the sunlight and/or artificial light. The selected photosensitizers/photocatalysts were the semiconductors (PC-1 and PC-2), the oxidizers (PC-3, PC-4, PC-5 and PC-6), the aromatic ketone (PS-7) and the aromatic amine(PS-8). The test toxic pollutants included the organophosphorus insecticide dichlorvos (DDVP), the dicarboximide fungicide procymidone, and the gasoline additive, methyl tert-butyl ether(MTBE) as the organic pollutants, and Pseudomonas putida, Phytophthora capsici, Escherichia coli and Salmonella typhimuriums as the pathogenic organisms. In the case of dichlorvos, all the photocatalysts selected showed more accelerated photodegradation than the control without photocatalyst under both the sunlight and artificial light. Whereas, only the photocatalyst PC-1 accelerated the degradation of MTBE about 17 times more than the control under both the sunlight and artificial light. Procymidone was much more degraded by the photosensitizer PS-8 and the two photocatalysts (PC-1, PC-6) than by PS-7. In the preliminary experiments to diminish the population of the microorganisms in the air, the photocatalyst-1 added to the microbial suspensions obviously inhibited the microbial growth under the artificial light. The photocatalyst-1 showed the bactericidal activity against Salmonella typhimurium spread on the nutrient broth agar medium. These results suggest that the photosensitizers/ photocatalysts under the light can remove some air pollutants and hence they can be used to reduce the exposure of the workers in the horticultural facilities and/or the public in the environment to the harmful pollutants.

몇가지 작물중 침투성 살충제 Carbofuran의 잔류량 분석

이재구,최신종,경기성,안기창,권정욱 충북대학교 농업과학기술연구소 1999 農業科學硏究 Vol.16 No.-

In order to ascertain the safety of the systemic insecticide carbofuran - treated crops. garlic, peanut and potato were collected randomly from markets near the major producing farms and analyzed for the residues of carbofuran and its main metabolite, 3-hydroxycarbofuran. The in vitro metabolism of carbofuran in phosphate buffer extracts of the crops was investigated. The results obtained were as follows. 1.The recoveries of carbofuran and 3- hydroxycarbofuran from the spiked samples were 92~ 100% in all samples. The detection limit and minimum amount of carbofuran detected were 0.02ppm and 0.1ng, and those of 3-hydroxycarbofuran 0.06ppm and 0.3ng, respectively. 2.Two mature garlic samples out of 20 contained 0.13 and 0.07ppm of carbofuran, respectively, showing a detection frequancy of 10%. The residue level was less than the maximum residue limit(0.5ppm) set by the health authorities in Korea. Only one mature garlic sample out of 20 contained 0.13ppm of 3-hydroxycarbofuran. 3.The residues of carbofuran and 3-hydroxycarbofuran in the immature garlic, peanut and potato samples were less than the detection limits. 4.The application of carbofuran to the fields of garlic, peanut and potato would be safe, considering that the estimated maximum acceptable daily intake of carbofuran from garlic was 0.0007mg which is 0.13% of the maximum acceptable daily intake(0.55mg) . 5.Carbofuran was hydrolyzed in vitro mainly to carbofuran phenol(m/z 164) in phosphate buffer extracts of the three crops in contrast to the major oxidative metabolism in situ. The amount of the metabolite increased with the incubation time.

Identification of quantitative trait loci associated with rice eating quality traits using a population of recombinant inbred lines derived from a cross between two temperate japonica cultivars

Kwon, Soon-Wook,Cho, Young-Chan,Lee, Jeong-Heui,Suh, Jung-Pil,Kim, Jeong-Ju,Kim, Myeong-Ki,Choi, Im-Soo,Hwang, Hung-Goo,Koh, Hee-Jong,Kim, Yeon-Gyu Springer-Verlag 2011 Molecules and cells Vol.31 No.5