교내 실내 공기에서 부유 미생물의 분포

박창은,임미소,이다은,김설아,강재원 남서울대학교 2010 남서울대학교 논문집 Vol.16 No.2

The pathogenic and non-pathogenic microorganism have been isolated from the indoor airborne, the closest environment of human beings. Our purpose were to investigate the distribution of fungi and bacteria in indoor airborne sampled from 7 locations in Namseoul University for 2 months from September to October, 2010. The isolated bacteria were identified by Gram stain and biochemical test using VITEKTM system, also The fungus were identified by LPCB. The experiment on microorganism concentration of indoor air carried out and the average of total microorganism was measured. When airborne bacteria were isolated and identified. The isolation rates of Gram positive cocci, Gram positive bacilli, Gram negative bacilli, and Gram negative cocci were 38.3%, 22.4%, 2.7%, 0%, respectively. In Gram positive cocci, the most strains were identified as Micrococcus spp. In Gram positive bacilli, the most strains were identified as Bacillus spp. The frequently isolated fungi were Aspergillus sp, Penicillium sp, Alternaria sp, Rhizopus sp, Mucor sp. respectively. Further systematic studies are necessary with an emphasis on species identification. Key Words : Microorganism, Fungus, Indoor Airborne, Micrococcus, Aspergillus

교내 수도꼭지형 냉온수기의 생수 배출 부위와 생수에 존재하는 미생물의 분포

박창은,김설아,임미소,이다은,박유진 남서울대학교 2010 남서울대학교 논문집 Vol.16 No.1-1

The distributed species and number of viable microorganisms in drinking water were monitored according to water dispenser maintenance. our purpose was to investigate the distribution of bacteria in drinking water dispenser. To analyze possible dispenser contaminations sampling were performed from 14 locations in Namseoul University for 3 months from March to May, 2010. The isolated bacteria were identified by Gram stain and biochemical test using VITEKⅡ systems. The microorganism concentrations around the water discharge areas were measured and the average of total microorganisms was determined. The number of bacteria were measured by McFarland turbidity. The water and water discharge areas were separated and identified. The isolation rates of Gram positive cocci and Gram negative bacilli were 56.5%, 17.4% respectively. The frequently isolated bacteria were Staphylococcus epidermidis, Enterobacter aerogenes, Enterbacter sakazakii, Alcaligenes faecalis, Acinetobacter baumannii, Staphylococcus hominis, respectively. Further systematic studies are necessary with an emphasis on species identification. Key Words : Microorganisms, Water Discharge Areas, Drinking Water, McFarland

Chitin과 Chitosan이 흰쥐의 Cadmium중독과 지방대사에 미치는 영향

김미경,설은영 이화여자대학교 생명과학연구소 1994 생명과학연구논문집 Vol.5 No.-

This study was performed to investigate the effect of dietary chitin & chitosan on cadmium(Cd) toxicity and lipid metabolism in rats. Forty-two male rats of Sprague-Dawley strain weighing 137+-g were blocked into 6 groups according to body weight, and were raised for 4weeks. Cadmium chloride was given at the level of 0 or 400ppm in diet and chitin and chitosan wre given at the level of 0 or 4% (w/w) of diet. The results are summarzed as follow. Chitosan decreased the toxicity of Cd on liver, kidney and femur and increase the Cd content of fecal excretion. Chitosan increased the lipid & cholesterol content of fecal excretion by combining with lipid and bile acid. Chitosan decreased lipid, cholesterol and TG content in serum and liver by combining with lipid and bile acid. Chitin was less effective than chitosan in decreasing of Cd toxicity and lipid content of rat.

폐경기 증후군 환자에서 Cyclofenil의 치료 효과

김덕윤,고은미,우정택,양인명,김진우,김영설,김광원,최영길 최신의학사 1992 最新醫學 Vol.35 No.10

자료포락분석(DEA)를 이용한 보건의료의 효율성 측정

김남송,박홍섭,김은진,김설화,김정숙,김현아,김경숙,신지혜,최은정,양은진,유선미,유수진 圓光大學校 醫科學硏究所 2007 圓光醫科學 Vol.22 No.1

건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.

NST Re-consultation during Nutritional Therapy in Korea

( Eun-mi Seol ),( Yun-suhk Suh ),( Dal Lae Ju ),( Hye Jung Bae ),( Hyuk-joon Lee ) 한국정맥경장영양학회 2017 한국정맥경장영양학회 학술대회집 Vol.2017 No.-

Objective: The objective of this study is to evaluate the reasons of NST re-consultation during nutritional therapy in patients who are admitted in Korea. Methods: From January to December 2016, 4,527 cases of nutritional support team (NST) consultation for adult patients (more than 18 years old) at Seoul National University Hospital were reviewed retrospectively. More than 2 times of consultation during same hospitalization period was assumed as “NST re-consultation”. We analyzed the reasons of NST re-consultation according to the type of current nutritional support. Results: NST re-consultation rate was 46.8% (n=2,117). The reasons of NST re-consultations included (1) changes of nutritional provision method (n=1,014, 47.9%), (2) complication related to artificial nutrition (n=700, 33.1%), (3) routine follow-up (n=303, 14.3%), (4) home nutritional therapy (n=80, 3.8%), and (5) others (n=20, 0.9%). Re-consultation rate of enteral nutrition (EN) was 55.7% (988/1,773) and that of parenteral nutrition (PN) was 41.0% (1,129/2,754). Among complication related to artificial nutrition (n=744), EN-related problems were composed of 49.9% (n=371) and included (1) diarrhea (n=140, 18.8%), (2) calorie deficiency (n=99, 13.3%), (3) gastro-intestinal trouble (n=48, 6.5%), (4) electrolyte imbalance (n=39, 5.2%), and (5) aspiration (n=13, 1.7%). PN-related problems were composed of 50.1% (n=373) and included (1) electrolyte imbalance (n=100, 13.4%), (2) liver function abnormality (n=87, 11.7%), (3) calorie deficiency (n=85, 11.4%), (4) gastro-intestinal trouble (n=19, 2.6%), and (5) blood stream infection (n=16, 2.2%). Conclusion: In tertiary referral hospital in Korea, almost a half of patients who received artificial nutrition were reconsulted to NST for many reasons. Among them, 33% of re-consultations were associated with complication related to artificial nutrition. Considering both EN and PN had various kinds of related problems, multidisciplinary approach to solve the problem is required.

성인 입원 환자에서의 영양치료 관련 합병증: 국내 다기관 연구

설은미 ( Eun-mi Seol ),권계숙 ( Kye Sook Kwon ),김정구 ( Jeong Goo Kim ),김정태 ( Jung-tae Kim ),김지훈 ( Jihoon Kim ),문선미 ( Sun-mi Moon ),박도중 ( Do Joong Park ),박정현 ( Jung Hyun Park ),박제훈 ( Je Hoon Park ),박지영 ( Ji Y 한국정맥경장영양학회 2019 한국정맥경장영양학회지 Vol.11 No.1

Purpose: Nutritional therapy (NT), such as enteral nutrition (EN) or parenteral nutrition (PN), is essential for the malnourished patients. Although the complications related to NT has been well described, multicenter data on symptoms in the patients with receiving NT during hospitalization are still lacking. Methods: Nutrition support team (NST) consultations, on which NT-related complications were described, were collected retrospectively for one year. The inclusion criteria were patients who were (1) older than 18 years, (2) hospitalized, and (3) receiving EN or PN at the time of NST consultation. The patients’ demographics (age, sex, body mass index [BMI]), type of NT and type of complication were collected. To compare the severity of each complication, the intensive care unit (ICU) admission, hospital stay, and type of discharge were also collected. Results: A total of 14,600 NT-related complications were collected from 13,418 cases from 27 hospitals in Korea. The mean age and BMI were 65.4 years and 21.8 kg/m². The complications according to the type of NT, calorie deficiency (32.4%, n=1,229) and diarrhea (21.6%, n=820) were most common in EN. Similarly, calorie deficiency (56.8%, n=4,030) and GI problem except for diarrhea (8.6%, n=611) were most common in PN. Regarding the clinical outcomes, 18.7% (n=2,158) finally expired, 58.1% (n=7,027) were admitted to ICU, and the mean hospital days after NT-related complication were 31.3 days. Volume overload (odds ratio [OR]=3.48) and renal abnormality (OR=2.50) were closely associated with hospital death; hyperammonemia (OR=3.09) and renal abnormality (OR=2.77) were associated with ICU admission; “micronutrient and vitamin deficiency” (geometric mean [GM]=2.23) and volume overload (GM=1.61) were associated with a longer hospital stay. Conclusion: NT may induce or be associated with several complications, and some of them may seriously affect the patient’s outcome. NST personnel in each hospital should be aware of each problem during nutritional support.

중환자 간호사의 호스피스,완화의료에 대한 태도와 이에 영향을 미치는 요인

설은미 ( Eun Mi Seol ),고진강 ( Chin Kang Koh ) 서울대학교 간호과학연구소 2015 간호학의 지평 Vol.12 No.2

Purpose: The study purpose was to describe critical care nurses’ attitudes toward hospice and palliative care and their related factors. Methods: In this cross-sectional descriptive study, 175 critical care nurses who worked at a general hospital in Seoul participated via self-report survey. The Frommelt Attitude Toward Care of the Dying Scale was used to measure their attitudes, and a palliative care quiz for nursing was used to measure their knowledge about hospice and palliative care. Results: Education level, duration of nursing employment, duration of critical care nursing employment, and knowledge about hospice and palliative care were significantly associated with nurses’ attitudes. In the multiple regression analysis, education level, and duration of nursing employment were significant predictors of nurses’ attitudes. Conclusion: These findings suggest that education programs to improve nurses’ knowledge about hospice and palliative care should be developed. These will help critical care nurses obtain a positive attitude toward hospice and palliative care.

Efficacy of adjuvant radiotherapy in non-extremity soft tissue sarcoma with moderate chemosensitivity

Lee, Eun Mi,Kim, Dong Hyun,Kim, Do Young,Seol, Young Mi,Choi, Young Jin,Kim, Hyojeong The Korean Society for Radiation Oncology 2018 Radiation Oncology Journal Vol.36 No.4

Purpose: Soft tissue sarcoma (STS) is a rare and heterogeneous cancer with over 50 known subtypes. It is difficult to understand the role of adjuvant treatment in STS. We aimed to determine the benefits of adjuvant treatment for a rare STS subset: non-extremity STS with moderate chemosensitivity. Materials and Methods: We reviewed medical records from Pusan National University Hospital and Kosin University Gospel Hospital, which had detailed pathological reports on patients diagnosed between 2006 and 2016. The most important inclusion criterion was resection with curative intent. We grouped STS by chemosensitivity based on reported data and analyzed non-extremity STS with moderate chemosensitivity. Results: We investigated 142 patients with 20 pathological subtypes of STS. Eighty-six patients had extremity STS and 56 had non-extremity STS. Thirty-eight of 56 patients were categorized as having moderate chemosensitivity. Seventeen of 38 patients (44.7%) received adjuvant radiotherapy and 14 (36.8%) received adjuvant chemotherapy. A log-rank test showed longer disease-free survival (DFS) in the adjuvant radiotherapy group than in the group treated without adjuvant radiotherapy (not reached vs. 1.468 years, p = 0.037). Multivariate Cox proportional hazard analysis, with covariates including age, stage, resection margin, adjuvant chemotherapy, and adjuvant radiotherapy, revealed that adjuvant radiotherapy was associated with longer DFS (odds ratio = 0.369, p = 0.045). Overall survival was not correlated with adjuvant radiotherapy. Conclusion: Adjuvant radiotherapy may be associated with longer DFS in patients with non-extremity STS with moderate chemosensitivity.