우리나라 산업의 정밀측정기술 수준분석

안웅환,남경희,안병덕,박병선 한국생산성학회 2003 生産性論集 Vol.17 No.3

The precision measurement technology is the infrastructure of industry technology and thus it is the critical element in the quality and hi-tech products. Nevertheless, the precision measurement technology in Korean industry is the lower level of the advanced state. In this study, we survey the demand of precision measurement technology including instrument and technologies in Korean industry, and provide the objective data on the level of precision measurement technology based on the report "A Study on the Current Status of Precision Measurement in Korea(KRISS, 2001)" . We summarize contents on the precision measurement technology in Korean industry, provide the assessment model for the level of precision measurement technology, and analyze the results of these. The level of the precision measurement technology of National Standards Institution, MISS, approaches those of the advanced state, but levels of the precision measurement technology in Korean industry are 2-3 years behind levels of National Standards Institution. Analysis model and results are analyzed for the important index to compare the levels of the precision measurement technology in Korean industry. Therefore, it is expected to provide the development for precision measurement technology and improve the system of precision measuring instruments, level of precision and accuracy, calibration, technical manpower for measurement etc. in Korean industry.

정신분열병 환자에서 존속살인의 임상적 특성

안병훈,최상섭,안성호,하태현,김선범,권경희,김정현 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.4

Objectives : This study aimed to describe the demographic, clinical and offense characteristics of the patients with Schizophrenia who committed parricide. This study also investigated the risk factors of parricide by comparing with characteristics of stranger killers to prevent the tragic offense. Methods : The sample consisted of 88 schizophrenic patients who committed homicide, 59 of them committed parricide and 29 of them killed strangers. Medical chart review regarding demographic and clinical characteristics as well as offense Characteristics was conducted. The information that was difficult to be obtained through chart review was acquired by direct interview. Results : Parricide group had earlier age of onset, more conflicts with the victims, more violence history toward victims and more offense provoking events than stranger killing group. Parricide group showed higher rate of past treatment than that of stranger killing group. However drug compliance at the time of offense was low in both groups. Offense provoking events in the parricide group included blaming, threatening a forced hospitalization or medication toward patients. The most common Psychiatric symptoms associated with homicide were threat/control override (TCO) symptoms, delusional perception, commanding auditory hallucination and especially with parricide, Capgras syndrome (CS). Conclusion : Interaction between psychotic symptoms such as TCO, CS and underlying emotion toward victims are likely to be associated with parricide. Mental health professionals are expected to play an important role in preventing this tragic offense by active history taking of the violence and effective management with active caregiver education/intervention of intrafamilial conflicts.

동종 골수이식을 시행받은 환자에서 폐색성 세기관지염에 의하여 발생한 자발성 기종격동과 피하 기종

이병환,이제중,이연경,안재숙,김여경,황호인,박무림,조상희,정익주,김형준 대한조혈모세포이식학회 2002 대한조혈모세포이식학회지 Vol.7 No.2

저자들은 만성골수성백혈병으로 동종 골수이식과 이식편 부전으로 인하여 추가적인 말초혈액 조혈모세포이식을 시행 받은 환자에서 만성 이식편대숙주질환과 그 폐 합병증인 폐색성 세기관지염에 동반된 자발성 기종격동과 피하 기종이 병발한 1예를 경험하였기에 이를 보고하는 바이다. Obstructive lung disorders following after allogeneic bone marrow transplantation (BMT) in association with graft- versus-host disease (GVHD) contribute significant morbidity and mortality. We report a case of a 28-year-old man who developed spontaneous pneumomediatinum and subcutaneous emphysema complicating bronchiolitis obliterans after allogeneic BMT. He received an allogeneic BMT for chronic phase of chronic myeloid leukemia. Five months after BMT, he was boostered by allogeneic peripheral blood stem cells from the same donor due to graft failure. One month after the boostering, chronic GVHD developed and were treated with cyclosporine and steroid. The patients developed spontaneous pneumomediatinum and subcutaneous emphysema secondary to severe bronchiolitis obliterans 4 months after boostering donor cells. The air-leak syndromes were recovered by conservative management, including high-flow oxygen.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

蜂毒藥鍼이 脊髓內 痛症關聯 神經細胞의 活性에 미치는 影響

鄭善喜,李栽東,高炯均,安秉哲,崔道永,朴東錫 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

In spite of the use of Bee Venom aqua-acupuncture in the clinics, the scientific evaluation of effects is not enough. Bee Venom aqua-acupuncture is used according to the stimulation of acupuncture point and the chemical effects of Bee Venom. The aims of this study is to investigate the analgegic effects of the Bee Venom aqua-acupuncture, through the change of writhing reflex and the change of c-fos in secondary neurons in the spinal cord. Materials and Methods : Pain animal model was used acetic acid method. The changes of writhing reflex of the mice which were derived pain by injecting acetic acid into the abdomen, after stimulating Bee Venom aqua-acupuncture on Chungwan(CV12) were measured. We used Fos immunohistochemical technique to study the neuronal activity in the spinal cord. Results : 1.Expression of c-fos in superficial dosal horn(SDH), nucleus proprius(NP) and neck of dorsal horn(N) on 6~9th thoracic spine decreased significantly at 2.5×10-4g/kg Bee Venom aqua-acupuncture, compared with saline-acetic acid group. 2.The numeral change of Fos-LI neurons on the NP, N, and ventral gray(V) on 6~9th thoracic spine, SDH on 9~11th thoracic spine, and SDH and V on 11~13th thoracic spine decreased significantly at Chungwan(CV12) Bee Venom aqua-acupuncture, compared with saline-acetic acid group. 3.The correlation between the numbers of writhing reflex and Fos-LI neurons in T6-13 segment was statistically statistically significant at Chungwan(CV12) Bee Venom aqua-acupuncture. Conclusion : This study shows that the Bee Venom aqua-acupuncture on Chungwan(CV12) decreases the numbers of Fos-LI neurons. As the analgegic effects of Bee Venom aqua-acupuncture is recognized. Bee Venom aqua-acupuncture treatment is expected for pain modulation. In order to use it in many ways. more researches are needed for the dose and stability of Bee Venom aqua-acupuncture.

치성 각화성 낭종에 대한 고찰

송승희,이선재,조갑주,서영진,고부일,유기준,박영주,안병근 한림대학교의료원 1994 人間科學 Vol.18 No.11

무균성 수막염 환자에서 분리한 enterovirus의 혈청형 및 계통발생학적 분석

이정희,안병윤,반성환,김상현,김의종 대한임상미샐물학회 2000 Annals of clinical microbiology Vol.3 No.2

베체트씨병에 동반된 복부 대동맥 동맥류의 스텐트 삽입술 1 예 : Treatment with Endovascular Stent Graft

허웅,안정수,황지영,김현지,강보리,나현희,이건주,변영섭,고충원,이병권 인제대학교 백병원 2003 仁濟醫學 Vol.24 No.1

Behcet's disease is an inflammatory disorder of unknown cause, characterized by recurrent oral aphthous ulcer, genital ulcers, ocular manifestations, and skin lesions. Large-vessel involvement of both arterial and venous system appears in 7-29% of patients, and it is major cause of morbidity and mortality. Venous involvement, including superficial thrombophlebitis and deep vein thrombosis, is more frequent. Arterial manifestations occurs infrequently and presents with aortitis or arterial aneurysm and arterial thrombosis. Arterial aneurysms or occlusions which occur in the systemic or the pulmonary arterial bed are present in approximately 2 to 3% of patients with Behcet's disease and accounts for only 12% of vascular complication. Aneurysms are more frequent than occlusions and are mostly present in the pulmonary arteries and abdominal aorta. They have poor prognosis because of rupture with fatal outcome and surgical treatment is necessary. But, Surgical treatment often difficult and may lead to formation of further false aneurysms at the site of vascular anastomosis. Endovascular stent graft placement emerged as an alternative treatment that is less invasive with a lower risk. We experienced a case of abdominal aortic aneurysm in 36-year-old man with Behcet's disease. The patient was diagnosed by CT scan and treated with percutaneous endovascular stent graft.

3급 부정교합 환자와 정상인에 있어서 하악소설과 Sigmoid Notch간의 거리에 관한 비교연구

박해승,안병근,이건주,김선해,박영주,유기준 한림대학교의료원 1994 人間科學 Vol.18 No.2

약관절에 대한 외과적 적근방법

조갑주,송승희,이선재,서영진,고부일,박영주,안병근 한림대학교의료원 1994 人間科學 Vol.18 No.10