太谿穴의 臨床 活用에 대한 文獻考察

구성태,송문영,강정묵,김용명,박보라,이은석,홍정아,김경식,손인철 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Literally, the mean of Tae-gye is highest brook. And on the basis of the acupuncture theory, Tae-gye point is the Soo earth point and source point of the Kidney Channel as well. In addition, Tae-gye point is one of the Yang-Returning Nine points. We were trying to study bibliographically on the Tae-gye point because Tae-gye point can be used very broadly across the symptoms in the theoretical aspect described above. As a results, we found out that according to the classical books of acupuncture, Tae-gye point is entering point of the Meridian Water as a source point and can be used at both Kidney-Sufficient Syndrom and Kidney-Deficient Syndrom. And Tae-gye can be applied to the disease of kidney or bladder that is urogenital symtoms, Also, Tae-gye is an useful option of tooth-ache, asthma, indigestion, constipation, edema etc whose cause is related with decrease of Kidney ki.

개에서 결직장 연접부의 림프종 1례

이재일,이수진,김영석,김명진,조성환,신상태,이영원,김명철 충남대학교 수의과대학 동물의과학연구소 2003 動物醫科學硏究誌 Vol.11 No.-

A five years old female Shih-tzu was referred to the veterinary medical teaching hospital at Chungnam national university with soft bloody diarrhea and tenesmus. On rectal palpation, solid mass was palpated in colorectal region. In radiographs, small intestine was deviated cranially, descending colon and rectal junction were deviated caudoventrally in lateral projection of the abdomen. In ultrasonographs, hypoechoic nodulation of mesenteric lymph node in colorectal junction, mixed echoic thickening of colorectal wall and irregular margination were observed. Rectal endoscopy revealed that colorectal men was partially obstructed due to compression of the mass. Also, severe ulceration, inflammation and hemorrhage were also observed in descending colon. The mass was resected through the laparotomy. In histopathology, it was diagnosis of lymphoma in the colorectal junction.

Peroxiredoxin V Regulates Aco2, Acadm, and Acox1 Activity in Hypoxic Kidney

Tae‐Hoon Lee,Hee‐Young Yang,Joseph Kwon,Hoon‐In Choi,Lina Ren,Ung Yang,Byung‐Ju Park,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

Peroxiredoxin V, an atypical thioredoxin peroxidase, is widely expressed in mammalian tissues. In addition, Prdx V is localized in mitochondria, peroxisome, cytosol, and nucleus. Prdx V has been reported to protect a wide range of cellular environments as antioxidant enzyme, and its dysfunctions may be implicated in several diseases, such as cancer, inflammation, and neurodegenerative disease. Identification and relative quantification of proteins affected by Prdx V may help identify novel signaling mechanisms that are important for oxidative stress response. However, the role of Prdx V in the modulation of hypoxia‐related cellular response is not studied yet. In order to examine the function of endogenous Prdx V in hypoxic condition in vivo, we generated a transgenic mouse model with Prdx V siRNA expression controlled by U6 promoter. Of many tissues, the knockdown of Prdx V expression was displayed in kidney, lung, and liver, but not spleen and skin. We conducted on the basis of nano‐UPLC‐MSE proteomic study to identify the Prdx V‐affected protein networks in hypoxic kidneys. In this study, we identified protein networks associated with oxidative stress, fatty acid metabolism, and mitochondrial dysfunction. Our results indicated that Prdx V affected to regulation of kidney homeostasis under hypoxia stress.

경남지역의 토양 및 농작물중 게르마늄 함량

이성태,이영한,이홍재,조주식,허종수 한국환경농학회 2005 한국환경농학회지 Vol.24 No.1

양질의 기능성 농산물 생산을 위하여 게르마늄의 농업적 이용에 대한 기초 자료를 제공하고자 경남지역의 토양을 중심으로 지역, 지형, 토양유형 및 토성별 게르마늄 함량과 자연상태에서 재배한 농작물별 게르마늄 함량을 조사하여 그 분포특성을 검토한 결과는 다음과 같다. 토양중 게르마늄 함량을 분석할 결과 성남지역 논 토양 평균 함량은 0.24 mg/kg 이었고, 마산시, 진주시 및 하동군 지역이 0.30 mg/kg 이상으로 높았다. 지형별로는 홍적대지가 0.26 mg/kg으로 약간 높았으나 지형에 따른 큰 차이는 없었다. 토양유형별 게르마늄 함량은 보통답이 0.27 mg/kg으로 사질답과 습답에 비하여 높았으며, 토성별로는 미사질양토가 0.27 mg/kg으로 비교적 높았다. 일반농작물중 게르마늄 함량은 곡류>채소류>과일류 순으로 높았고, 쌀과 보리는 각각 약 68 및 48 μg/kg의 게르마늄을 함유하고 있었으며, 단감과 배는 각각 약 11 및 23 μg/kg으로 전반직으로 낮을 수준이었다. 채소류중 게르마늄 함량은 엽채류>근채류>과채류 순으로 높았으며 특히 상추와 열무중 게르마늄 함량이 각각 약 62 및 65 μg/kg으로서 높았다. 약용작물중 게르마늄 함량을 신선초(Angelica keiskei), 토천궁(Ligusticum chuanxiong), 인삼(Panax ginseng), 삽주(Atractylodes macrocephala), 백지(Angelica dahurica), 맥문동(Liriope platyphylla) 및 도라지(Platycodon grandiflorum)에서 100 μg/kg 이상으로 게르마늄 함량이 높았으며, 선학초(Agrimonia pilose) 및 일당귀(angelica acutiloba)의 함량은 각각 37 및 30 μg/kg으로 낮았다. To investigate the germanium content in paddy soil in Gyeongnam province, 310 paddy soil samples were collected at 19 areas in Gyeongnam, Ulsan and Busan. Contents of germanium in paddy soils were analyzed in different topographies, soil types and soil textures. Average content of germanium in Gyeongnam was 0.24 mg/kg, those of Masan, Jinju and Hadong were above 0.30 mg/kg. Germanium content with different topographies were no difference. Germanium contents in different soil types were 0.27 mg/kg in well adapted soil and 0.23 mg/kg in poorly drained soil. Germanium contents in different soil textures were 0.27 mg/kg in silt loam and 0.23 mg/kg in sandy loam. To determine germanium content on agricultural product in the field, content of germanium in cereals, vegetables and fruits were analyzed. Germanium content of agricultural product was high in the order of cereals>vegetables>fruits. In case of vegetables, germanium contents were high in the order of leaf vegetables>root vegetables>fruit vegetables. Germanium contents were high with 62 and 65 μg/kg in lettuce and young radish, respectively. To analyze the germanium content in medicinal plant, samples were collected from 19 medicinal plants at Hamyang areas. Germanium contents in Angelica keiskei, Ligusticum chuan wng, Panay ginseng and Atractylodes nacrocephala were relatively high with 100 μg/kg above.

청장년에서 관찰된 관상동맥의 비죽종성 석회화와 동맥류 : 부검증례보고

이지신,이영직,박종태 大韓法醫學會 1997 대한법의학회지 Vol.21 No.1

Coronary artery calcification(CAC) is found frequently in the atheromatous plaques. CAC is known to have increased frequency above 40 years. CAC without evidence of atherosclerosis in young adults is quite rare, however, CAC combined with aneurysms in young adults have been infrequently reported in patients with a past history of a Kawasaki disease in child. We report an autopsy case showing CAC and aneurysm in the absence of macroscopically identified atherosclerotic lesions in a healthy 23-year-old man. The autopsy examination revealed aneurysmal dilatation of the right coronary artery, which was connected with calcified lesion. A calcified lesion of the left anterior descending coronary artery was aslo noted. Microscopically, aneurysmal wall was non-specific except for hyalinized wall and foci of calcification. A striking histologic finding of calcified mass was ring calcification along the wall of the coronary artery. Antecedent Kawasaki disease in the past was suggestive as other reports.

근대국어 '-어이다' 구성의 통사적 특성에 대하여

이태영 대한언어학회 1998 언어학 Vol.6 No.2

Lee, Tae young. 1998. Syntactic Properties of '-aida' in Modern Korean. Linguistics, 6-2, 161-182. The purpose of this thesis is to examine the Syntactic Properties of '-aida(-어이다), - h?n?ida(-어 ㅎㄴ이다) in Modem Korean in order to seek for the pragmatic function of 'ida(이다)'. Traditionally, 'y /ya(여/야), /a(어/아)' of '- ida' has been treated as prefinal ending. In this paper, however, 'ya/ya, a/a' will be treated as connective ending, because contraction forms of 'y /ya, /a' do not appear, but contraction forms of '-so(소), -o(오), -de (데), -n?i(니)' appear. In conclusion, '- ida' is generated by contraction of '- h?n?ida', and '- ida' has 'verb stem + connective ending + ida' construction. As a result, 'ida' has pragmatic function. (Chonbuk University)

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

산재지정병원 이용 후 산재요양환자에 대한 만족도 조사

이화평,임형준,주영수,권영준,강희태,김정민,조성식,이태경,윤종완 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.3

한국인 관상동맥의 변화양상에 대한 형태학적 연구

이상용,권태정,정낙은,서중석,이한영,이원태 大韓法醫學會 2002 대한법의학회지 Vol.26 No.1

Experimental investigation of macroscopic material nonlinear behavior and microscopic void volume fraction change for porous materials under uniaxial compression

Lee, Eun Sun,Goh, Tae Sik,Lee, Jung Sub,Heo, Jin-Young,Kim, Gi-Baek,Lee, Chi-Seung Elsevier 2019 Composites Part B, Engineering Vol.163 No.-

<P><B>Abstract</B></P> <P>The purpose of this study was to simultaneously analyze the nonlinear behavior and the void volume fraction change of polyurethane foam (PUF) under a uniaxial compressive load through micro-scale and macro-scale viewpoints. The influence of micro-scale factors on the macroscopic properties of PUF was analyzed, along with the interrelationships between micro-scale and macroscopic properties. The microstructure of PUF was observed by analyzing the density. Various micro-analyses were also conducted, including those for energy absorption, Young's modulus, and recovery behaviors. Internal structure changes such as those in density and degree of compressive strain were analyzed by measuring the void volume fraction of each region in the specimen under a uniaxial compressive load. The elastic, plateau, densification, and fracture regions of the compressive test stress-strain curve were divided, analyzed, and compared with microscopic analysis results. Based on the results of the macro-micro-scale experiment, we analyzed influence and change process of microstructures on the compressive behavior of the PUF specimen in detail. This study shows that internal and overall changes in the compression process of various porous materials can be predicted under a uniaxial compressive load.</P>