과실이 크고 품질이 우수한 조생종 배 ‘금촌조생’ 육성

조광식(Kwang-Sik Cho1),손동수(Dong-Soo Son),강삼석(Sam-Seok Kang),김명수(Myung-Su Kim),홍경희(Kyung-Hui Hong),윤석규(Seok-Kyu Yun),조강희(Gang-Hui Cho),조현모(Hyeon-Mo Cho) 한국원예학회 2004 원예과학기술지 Vol.22 No.1

‘금촌조생’ 품종은 농촌진흥청 원예연구소 나주배연구소에서 1971년 ‘금촌추’의 품질을 개선하기 위해 당도가 높고 육질이 유연한 ‘단배’를 교배하여 1982년 1차 선발되었고, 1997년부터 5년 간 지역적응시험을 거쳐 2001년 최종 선발 및 품종보호출원 되었다. 수세는 비교적 강하고, 수자는 반개장성이다. 꽃가루가 풍부하며, 주요 재배품종과 교배친화성을 보인다. 또한 흑반병에 대하여 강한 포장저항성을 나타내었다. 숙기는 재배중인 ‘원황’ 품종보다 약 5일 정도 늦은 9월 3일로 추석에 출하하기 알맞은 품종이다. 과형은 ‘금촌추’와 같은 도원추형이고, 과피색은 황갈색이다. 과중은 593g이고, 당도는 13.2Bx이다. 육질은 유연하며 과즙이 풍부하고, 석세포가 없어 식미가 매우 우수하다. 그러나 과육선숙형 품종으로 원예적 수확기에도 과피에 녹색이 남지만, 완숙과가 되면 황갈색으로 착색된다. 상온저장 기간은 20일 정도로 다른 조생종에 비해 저장력은 좋은 편이다. ‘Geumchonjosaeng’ pear cultivar (Pyrus pyrifolia var. culta Nakai) originated from the cross between ‘Imamuraaki’ and ‘Danbae’ to improve the fruit quality of ‘Imamuraaki’ cultivar in 1971 at Naju Pear Research Institute of National Horticultural Research Institute (NHRI), Rural Development Administration (RDA). It was preliminarily selected in 1982 and named in 2001. The tree habit shows vigorous growth and upright spreading. It carries abundant pollen grains and shows cross compatibility with leading cultivars. Also it shows high resistance to black leaf spot (Alternaria kikuchiana) in the field condition. Optimum harvest time is around Sep. 3, which is 5 days later than that of ‘Wonwhang’, and it could satisfy consumer’s demand for high quality pear fruit in “Chuseok”. The obovate fruit shape resembles maternal parent, ‘Imamuraaki’ and skin color is green yellowish brown at normal harvesting time and gradually turned to yellowish brown at full ripennig state. Fruit weighs about 593 g, and the soluble solid content is 13.5 ˚Bx. The flesh is very soft and juicy and, rendering good eating quality. Shelf life is about 20 days under the ambient temperature, and it is a relatively long period as compare with other early season cultivars.

입원한 기분장애 소아청소년의 임상특성 : 주요 우울증과 양극성장애의 우울삽화 비교를 중심으로

임명호,조수철,백기청,이경규,김현우,홍강의 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.2

본 연구는 소아청소년에서의 우울증 및 조울증의 우울삽화에 대한 임상특성을 알아보고자 하였다. 1993년 3월 1일부터 1999년 10월 31일까지 ○○대학교 어린이 병원 소아청소년 정신과에 입원하였던 34명의 우울증 환아와 17명의 조울증 우울삽화 환아를 대상으로 병록지 기록을 통해서 이들의 사회인구학적 특성, 진단적 분류, 입원시 주 증상 및 문제점, 증상의 빈도, 주산기 모 병력과 아동기 발달력, 공존정신 질환 및 신경 심리학적 검사 가족의 임상적 특성, 가족 정신병리 및 가족 병력, 치료반응등에 대하여 조사하였다. 1) 우울증에서 남자의 비율이 여성의 경우보다 높았으며, 조울증 우울삽화에서는 남녀의 비율이 비슷하였다. 2) 평균 발병 연령은 조울증 우울삽화에서 14.1세, 우울중에서 12.8세로 우울증에서 일찍 발병하는 양상을 나타냈으며, 입원 횟수에 있어서는 조울증 우울삽화에서 우울증에 비해서 많았다. 3) 조울증 우울삽화와 우울증 모두에서 식물증상의 호소가 신체증상보다 많았으며, 자살사고 증상은 우울증에서, 공격적인 증상은 조울증 우울삽화에서 많았고, 정신병적 증상에서는 망상은 우울증에서 환각은 조울증 우울삽화에서 많이 나타났다. 4) 두 집단 모두에서 불안장애가 가장 많이 동반되었으며, 신체형 장애, 정신지체, 인격장애 등이 동반되었다. 5) 조울증 우울삽화와 우울증 모두 높은 가족력을 보였고, 특히 우울증은 아동 학대력과 가족의 부적절한 양육과 관련성을 보였다. 성인에서 조울증과 우울증이 분명한 임상적 차이를 갖고있는 것처럼 소아에서도 조울증 우울삽화와 우울증은 발병연령, 신체증상 및 식물증상을 비롯한 임상증상의 차이, 공존질환 등에서 서로 다른 임상 양상을 나타내었다. 중심 단어 : 주요 우울증ㆍ우울 삽화ㆍ임상 특성. The purpose of this study is to find out the characteristics of depressive episode about major depression and bipolar disorder in child and adolescent. The subjects of this study were 34 major depression patients and 17 bipolar disorder patients hospitalized at child and adolescent psychiatry in ○○ university children's hospital from 1st March 1993 to 31st October 1999. The method of this study is to review socio-demographic characteristics, diagnostic classification, chief problems and symptoms at admission, frequency of symptoms, maternal pregnancy problem history, childhood developmental history, coexisting psychiatric disorders, family psychopathology and family history and therapeutic response through their chart. 1) The ratio of male was higher than that of female in major depressive disorder while they are similar in manic episode, bipolar disorder. 2) Average onset age of bipolar disorder was 14 years 1 month and it was 12 years 8 months in the case of major depression As a result, average onset age of major depression is lower than that of bipolar disorder. 3) The patients complained of vegetative symptoms than somatic symptoms in both bipolar disorder and depressive disorder. Also, the cases of major depression developed more suicide idea symptom while the case of bipolar disorder developed more aggressive symptoms. In the respect of psychotic symptoms, delusion was more frequently shown in major depression, but halucination was more often shown in bipolar disorder. 4) Anxiety disorder coexisted most frequently in two groups. And there coexisted symptoms such as somartoform disorder, mental retardation and personality disorder in both cases. 5) The influence of family loading was remarkable in both cases. Above all, the development of major depression had to do with child abuse history and inappropriate care of family. It is apparent that there are distinctive differences between major depression and bipolar disorder in child and adolescent through the study, just as in adult cases. Therefore the differences of clinical characteristics between two disorders is founded in coexisting disorders and clinical symptoms including onset age, somatic symptoms and vegetative symptoms. KEY WORDS : Major depressive disorderㆍDepressive episodeㆍClinical characteristics.

유비쿼티스 센서 네트웨크에서의 저전력 상호인증 프로토클

조영복,정윤수,김동명,이상호,Cho Young-Bok,Jung Youn-Su,Kim Dong-Myung,Lee Sang-Ho 한국컴퓨터정보학회 2005 韓國컴퓨터情報學會論文誌 Vol.10 No.2

유비쿼터스 센서 네트워크에서 모든 센서노드들은 한정된 배터리로 통신에 참여하게 된다 기존의 인증방식을 사용하는 경우 많은 연산 수행이 필요하여 센서노드의 배터리를 과다하게 소모하여 센서노드의 동작 기간이 상대적으로 짧아지므로 네트워크 유지에 많은 어려움이 존재한다. 이 논문에서는 센서노드의 인증과정에서 전력 소비문제를 해견하기 위해 RM (RegisterManager)과 AM (AuthenticationManager)을 도입한 네트워크 구조를 제시하고, 노드의 상호인증을 통한 세션키를 발급하는 저전력 상호인증 프로토콜을 제안한다. RM과 AM은 개댈 센서노드에서 안전성을 보장하기 위해 수행되는 키 생성 및 암/복호화, 인증 과정을 센서노드 대신 처리하여 빠른 연산속도로 알고리즘을 처리한다. 따라서 센서노드의 인증에 소요되는 알고리즘 수행시간이 동일 서브넷에 존재하는 경우 평균 2.96$\%$, 서로 다른 서브넷에 존재하는 경우 평균 12.91$\%$ 빠르게 수행된다. 따라서 제안 방식은 센서 노드가 더 오랜 시간 통신에 참여할 수 있도록 하며, 센서네트워크의 크기가 증가할수록 효율적이다. All sensors in Ubiquitous sensor network have to communicate with limited battery If we adopt current authentication, there are difficulties to keep sensor network because heavy calculation in each sensor needs more power and lifetime of sensor could be short relatively because of the effect. This paper suggests network structure which is using RM(RegisterManarer) and AM(AuthenticationManager) to solve power Problem on authentication, and su99ests mutual-authentication protocol with low Power which supports a session key by mutual-authentication. RM and AM manage algorithm with fast calculation to keep the safety by doing key generation. encryption/decryption. authentication instead of each sensor node . Processing time to authenticate sensor node is 2.96$\%$ fast in the same subnet, and 12.91$\%$ fast in different subnet. Therefore. the suggested way Provides expanded lifetime of censor node and is more effective as sensor network size is bigger and bigger.

랫드에서 신우황청심원의 급성 및 아급성독성시험

오승민,남혜윤,김준수,연제덕,신대희,이진영,박대규,조명행,정규혁 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

The acute and subacute toxicity of New Woohwangchungsimwon(NWCH) which was used l-muscone as substitutive material of musk were investigated in S.D. rats. In intraperitoneal acute toxicity test, rats(Sprague-Dawley, SPF) were injected intraperitoneally with dosages of 0, 540, 750, 1,070, 1,500 and 3,000 ㎎/㎏. Body weights were significantly decreased at 540 ㎎/㎏ dose group in both sexes and abnormal autopsy findings were founded in both sexes at all treated groups. Intraperitoneal LD_50 of NWCH was 812.3 ㎎/㎏ in male and 872.3 ㎎/㎏ in female rats. In the subacute toxicity study, NWCH was administrated orally to both sexes of rats for 4 weeks as several doses(0, 320, 800 and 2,000 ㎎/㎏). There were neither dead animals nor significant changes of body weights during the experimental period. In addition, no differences were found between control and treated groups in clinical signs, urinalysis, hematology, serum biochemical analysis, and other findings. Above data strongly suggest that no observed adverse effect level of NWCH might be over 2,000 ㎎/㎏/day in this study.

돼지에서 정맥, 근육 그리고 경구 투여시의 enrofloxacin의 약물동태학

윤효인,김무열,박승춘,조준형,박병권,이내경,노상석,장범수,신광순,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

In order to characterize pharmacokinetic profiles according to route of a new enrofloxacin salt form (Enrotil®), it was given to 4 healthy pigs via oral (p.o.), intramuscular (i.m.) or intravenous (i.v.) administrations at a dose rate of 5 ㎎/㎏ body weight. Enrofloxacin (ENFX) in serum was detected by bioassay using E. coli BE1186 as a test organism. The biological elimination half-lives (t_1/2(β)) of ENFX were 6.76±0.99 h (i.v.), 7.16±2.30 h (i.m.) and 11.45±3.90 h (p.o.), Volume of distribution (Vd) of enrofloxacin was 2.20±0.31 L/㎏ (i.v.), 2.52±0.60 L/㎏ (i.m.) and 1.88±0.33 L/㎏ (i.m.). Mean residence time (MRT) was 8.77±1.26 h after i.v. injection and the maximal concentration time (Tmax) following p.o. and i.m. administration was 0.76±0.09 h and 0.60±0.12 h, indicating a rapid absorption from these routes. Bioavailibility (F) was calculated as 64.1% for p.o. administration and 59.71% for i.m. injections. In summary, the newly formulated enrofloxacin salt form has shown a high water solubility, rapid absorption and large tissue distribution, suggesting a potential antibacterials for oral application on a large scale in veterinary sectors.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

Tetragonal Phase Germanium Nanocrystals in Lithium Ion Batteries

Cho, Yong Jae,Im, Hyung Soon,Kim, Han Sung,Myung, Yoon,Back, Seung Hyuk,Lim, Young Rok,Jung, Chan Su,Jang, Dong Myung,Park, Jeunghee,Cha, Eun Hee,Cho, Won Il,Shojaei, Fazel,Kang, Hong Seok American Chemical Society 2013 ACS NANO Vol.7 No.10

<P>Various germanium-based nanostructures have recently demonstrated outstanding lithium ion storage ability and are being considered as the most promising candidates to substitute current carbonaceous anodes of lithium ion batteries. However, there is limited understanding of their structure and phase evolution during discharge/charge cycles. Furthermore, the theoretical model of lithium insertion still remains a challenging issue. Herein, we performed comparative studies on the cycle-dependent lithiation/delithiation processes of germanium (Ge), germanium sulfide (GeS), and germanium oxide (GeO<SUB>2</SUB>) nanocrystals (NCs). We synthesized the NCs using a convenient gas phase laser photolysis reaction and attained an excellent reversible capacity: 1100–1220 mAh/g after 100 cycles. Remarkably, metastable tetragonal (ST12) phase Ge NCs were constantly produced upon lithiation and became the dominant phase after a few cycles, completely replacing the original phase. The crystalline ST12 phase persisted through 100 cycles. First-principles calculations on polymorphic lithium-intercalated structures proposed that the ST12 phase Ge<SUB>12</SUB>Li<SUB><I>x</I></SUB> structures at <I>x</I> ≥ 4 become more thermodynamically stable than the cubic phase Ge<SUB>8</SUB>Li<SUB><I>x</I></SUB> structures with the same stoichiometry. The production and persistence of the ST12 phase can be attributed to a stronger binding interaction of the lithium atoms compared to the cubic phase, which enhanced the cycling performance.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-10/nn403674z/production/images/medium/nn-2013-03674z_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn403674z'>ACS Electronic Supporting Info</A></P>

[P8-220] Antioxidative Capacrty of Low-trans fat based on Corn Oil in Apo E deficient mice

Su-Jung Cho,Yun-Young Cho,Eun-Young Kwon,Hye-Jin Kim,Seon-Min Jeon,Ki-Teak Lee,Myung-Sook Choi 한국식품영양과학회 2008 한국식품영양과학회 학술대회발표집 Vol.2008 No.10

Receptor-Mediated Gene Delivery by Folate-PEG-Baculovirus in vitro and in vivo

CHO Chong-Su,CHO Myung-Haing,JE Yeon Ho,CHOI Jae Young,PARK In-Kyu,JIANG Hu-Lin,KIM You-Kyoung 大韓藥學會 2006 大韓藥學會 總會 및 學術大會 Vol.2006 No.2