상염색체우성 다낭신의 임상경과 및 합병증

이상주,이영모,이한규,최대은,박기현,이강욱,신영태 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Autosomal dominant polycystic kidney disease(ADPKD) is one of most common hereditary disorder. It is potentially fatal and the major mobilities are hypertension and renal failure. To elucidate clinical characteristics and outcomes of ADPKD, 67 ADPKD patients were analyzed retrospectively. The male to female ratio was 48 years for males and 42 years for females. The factors leading to the dignosis of ADPKD were flank or abdominal pain (46%), palpable abdominal mass (24%), incidental findings (18%), gross hematuria and headache. Urinalysis result showed hematuria (31%), proteinuria (19%), pyuria (18%). Among renal complications hypertension (67%) was the most common. Other complications were urolithiasis (16%) upper urinary tract infection (9%), cyst infection (7%). Azotemia was observed in 24% of cases. Echocardiography showed left ventricular hypertrophy in 24% and valvular regurgitation in 18% of cases, but there was no mital valve prolapse. Cerebrovascular events occurred in 6 cases (2 cases of intervertebral hemorrhage and 4 cases of cerebral infarction). Hipatic cyst were observed in 64% of cases. Eighteen cases culminated in end stage renal failure (ESRF) at an of 47. According to this study, the most common complications of ADPKD was hypertension (67%), ESRF (27%), and cerebrovascular event (9%). Hypertension was more frequently observed in increased creatinine group than normal.

횡문근융해증과 급성 신부전 및 범발성 혈관내 응고장애를 동반한 열사병 1예

최대은,박수진,권오경,이한규,이영모,이상주,나기량,이강욱,신영태 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Heat stroke is a life-threatening illness characterized by an elevated core body temperature that rises above 40% and central nervous system dysfunctions that results in delirium, convulsions, or coma. Heat stroke is subdivided into two forms, classic and exertional. Since strenuous exercise is one of the major exacerbating and precipitating factors, the incidence of exertional heat stroke is high among young adult, especially military personnel undergoing military training. Exertional heat stroke commonly causes rhabdomyolysis, lactic acidosis, acute renal failure, shock and pulmonary edema. We report a case of heat stroke with rhabdomyolysis, acute renal failure, disseminated intravascular coagulopathy(DIC) after strenuous exercise. A 18 year old man was admitted to the hospital because of loss of consciousness. He was a wrestler and he had tried to lose 6kg in weight by jogging and strenuous exercise on that summer day with hot temperature. The development of this illness was favoured by much clothes inappropriate for that environmental condition with a purpose to enhance sweating, and by restricted intake of water and food. On admission, the blood pressure was 80/50mmHg, and body temperature was 39.4℃ with stuporous mentality. Laboratory finding were as follows : in complete blood cell count, hemoglobin was 16.7g/dL and platelet count was 158,000/ mm³. In blood chemistry, AST 1061U/L, ALT 201U/L, BUN 30mg/dL, Cr 2.2mg/dL, LDH 941IU/L, CK 696IU/L were resulted. In arterial blood gas analysis, pH 7.39, pCO₂ 30mmHg pO₂ 86mmHg, HCO₃ 18.4mEq/L, O₂ saturation 96.7% were resulted. In urinalysis, specific gravity 1.025, protein 3+, erythrocyte 2+ were resulted. In brain imaging study, brain CT finding was normal. After appropriate treatments with rapid cooling, hydration and supportive care, he improved with alert mental status. On 2nd hospital day, in laboratory result, thrombocytopenia and coagulopathy were appeared and renal insufficiency was aggravated. So he was treated with platelet concentrate and fresh frosen plasma for DIC, and enough hydration for appropriate urine volume preservation. After all, On 22nd hospital day, he fully recovered and discharged. Nowadays, with followed for some duration, he is wellbeing with no complications.

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

인체 지방 및 간장조직 중 유기염소제류 및 PCB의 확인 및 정량기법 체계화 : 2차년도

이상기,양자열,김기욱,이수연,오승민,김대현,정규혁 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

가상교육 시스템의 상호작요적 모형 개발 및 구현

이홍길,방대욱 계명대학교 산업기술연구소 1998 産業技術硏究所 論文報告集 Vol.21 No.1

We proposed and interactive model of virtual education that can be applied on the realization of virtual university, and implemented a virtual education system that is a web system using plug-in programs and that links appropriately the known applications on the Internet. While other virtual education systems focus on a remote educations, our system realizes an interactive education that teachers and students interact each other on virtrual spaces such as virtual lecture room, virtual office, virtual self-studying room. In our system, it is simple to add new functions and is easy to update the system components because most of them are accomplished by the insertion and update of stand-alone Internet programs.

갑상선 분화암 환자의 경과 관찰에서 수술전·후 혈청 갑상선글로불린 측정의 유용성

이성진,원종철,김하영,한정희,이은주,김상욱,류진숙,문대혁,홍석준,안일민 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4·5

고립성 직장결핵 3예

이동수,정강욱,황도연,이형화,김대현,김영성,곽동협 대한내과학회 2003 대한내과학회지 Vol.64 No.1

저자들은 장결핵 중 발생 부위상 드문 곳으로 알려진 직장에 발생한 고림성 결핵을 3예 경험하였기에 문헌고찰과 함께 보고하는 바이다. Isolated rectal tuberculosis commonly involves sigmoid, ascending, or transverse colon. Rectal involvement in tuberculosis is uncommon and poorly characterized. Isolated rectal tuberculosis was defined as focal lesions of rectum in the abscence of demonstrable lesions in the small and large bowel. Diagnosis of rectal tuberculosis was based on characteristic endoscopic appearance of lesions, histopathologic feature of tuberculosis in biopsy material and response to antitubercular therapy. Three patients with isolated rectal tuberculosis were seen at Kwak's hospital. The lesions observed was classified according to macroscopic morphology as follows: ulcerative, hypertrophic and ulcero-hypertrophic. Clinical manifestations were non-specific and consists of rectal bleeding, fever, weight loss, constipation and abdominal pain. One of the three patients had coexisting tuberculous pleurisy. Response to antitubercular chemotherapy was good. (Koeran J Med 64:96-100, 2003)

치과 치료 경험이 아동의 치과의사와 치과 치료에 대한 태도에 끼치는 영향에 관한 조사 연구

허용욱,이광희,문필성,김대업 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.2

The purpose of this study was to investgated the effect of dental experience the attitude of children toward the dentist and the dental treatment.The subject of the study were 1,090 children from second grade to forth grade of three elementary schools of the Iksan city.The children were investgated by the questionnaire which cosisted of seven items about the attitude toward the dentist,the attitude toward the dental treatment,the dental treatment experience,the number of times of dental treatment,the last time of the dental visit,pain of dental treatment,and fear of dental treatment. There were significant differences among the grades in the attitude toward the dental treatment and in the attitude toward the dentist(P<0.01).Second grade children had the most negative attitudes.But,there were no differences between boys and girls.Girls felt more pain and fear than boys(P<0.01).There were significant relationships between the pain and the attitude toward the dentist,between the pain and the attitude toward the dentist, and between the fear and the attitude toward the dental treatment(P<0.01,all).The number of dental visit had significant relationship with the attitude toward the dental treatment(P<0.05).There was significant relationship between the pain and the fear between the attitude toward the dentist and the attitude toward the dental treatmen.

중등 컴퓨터과학교육을 위한 객체지향형 EPL '두리틀'의 적용 및 평가

권대용,길혜민,염용철,유승욱,進兼宗,靖久野,이원규 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.6

제 7차 컴퓨터교과 교육과정은 소프트웨어 활용 부분에 치중되어 컴퓨터과학에 관한 원리교육이 이루어지지 못하고 있다. 한편, ACM K-12 컴퓨터과학 교육과정 모델에 관한 보고서에서는 현재의 컴퓨터교육이 그릇된 방향이며 컴퓨터과학 중심의 컴퓨터교육을 위해서 프로그래밍언어 교육을 통한 원리교육의 중요성을 강조하고 있다. 본 논문에서는 프로그래밍 체험학습을 위한 객체지향 기반의 새로운 교육용프로그래밍언어인 두리틀(Dolittle)을 소개한다. 두리틀은 간결한 구문과 한국어와의 대응성, 인크리멘탈 방식의 프로그래밍, 수치, 문자열, 배열과 같은 알고리즘과 구조화, 텍스트 위주의 프로그래밍 등의 설계방침을 적용한 언어이다. 중학생을 대상으로 실제 수업에 적용해 보고 학습효과를 분석한 결과, 객체지향기반이지만 클래스나 상속 등의 개념을 모르고도 활용 가능한 교육용프로그래밍언어라는 것을 확인할 수 있었다. 또한 객체와 메소드 활용을 통하여 프로그래밍 결과를 쉽게 확인할 수 있고 오류 수정이 용이하므로, 학생들의 높은 흥미도를 유지하면서 학업성취도를 향상시키고 차후 학습으로의 연계가 수월하였다. Current computer education is difficult to educate basic concepts and principals of the computer science because the 7th curriculum of computer education is focused on the application of software. According to the ACM K-12 report about the computer science education model, current computer education is taking the wrong way and we should put the highly priority on the education of the fundamentals through programming languages for a better computer education oriented to the computer science. This paper introduces a new object-oriented educational programming language "Dolittle'". The design principals of Dolittle are simple syntax of Korean, incremental programming, text based programming, aliasing of function, and object-oriented programming. Being applied to middle school classes, we can confirm that Dolittle is easy to learn, and gives rise to high interest and keeps interest through a course,and also is of great practical use in class for programming novice.

지방정부 관료의 조직시민행동에 대한 LMX의 영향 분석

김대원, 이재욱 신라대학교 부산학연구센터 2011 부산연구 Vol.9 No.1

조직의 효과성과 효율성(생산성 및 능률성을 포함)을 높이기 위한 가장 중요한 요소중의 하나가 조직 구성원이며, 이들의 적극적인 협조와 노력이 부족할 경우 조직의 존립도 담보할 수 없다. 본 연구는 조직의 효과성을 높이기 위해서는 조직 구성원들의 조직시민행동이 선행되어야 한다는 전제하에 이를 높이기 위한 방안으로 LMX를 선정하여 이들간의 관계를 분석하는 데 목적을 둔다. 이를 위해 이론적 논의를 통해 사회교환론적 시각에서 LMX와 조직시민행동에 대한 경로변인들의 이론적 근거를 제시하고, 변인들간의 영향경로를 분석할 수 있는 연구가설과 연구모형을 설정한 뒤 가설을 검증한다. 분석자료는 부산 및 경남 지역의 관료들을 대상으로 하였으며, 분석 결과, LMX는 조직시민행동에 정(+)의 영향을 미치는 것으로 나타났다. 따라서 본 연구는 신자유주의 가치관이 지배하고 있는 현실에서 자칫 소외되기 쉬운 정서적 관리를 통해 조직시민행동을 자극할 수 있고, 이를 통해 조직의 효과성을 높일 수 있다는 것을 명확히 하였다는 점에서 의미를 가진다. Using a sample of 200 public workers from local government organizations in Korea, this article aims to investigate the relationship between leader-member exchange(LMX) and organizational citizenship behavior(OCB) of the followers. Data were collected on a structured questionnaire containing standard scales of LMX and OCB. After establishing the psychometric properties of the scales, hypotheses were tested through statistical analysis of the data. The reliabilities of the scales has been verified through using Cronbach's α coefficient. The study proved that LMX had significantly correlated to all dimensions of OCBs.