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혼합형 자가면역성용혈성빈혈과 동반된 Evans 증후군 1례
선길홍,윤찬영,박상곤,박경희,우정주,한경택,김진화,김영훈,정춘해,박치영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2
Evans syndrome is defined as a simultaneous or sequential occurrence of autoimmune hemolytic anemia and autoimmune thrombocytopenia. Autoimmune hemolytic anemia (AIHA) is usually induced by IgG warm autoantibody or cold-active IgM antibodies reacting specifically with antigens associated with a patient's RBC. AIHA is a fairly uncommon disorder, with estimates of the incidence at 1 to 3 cases per 100,000 per year. Mixed-type AIHA is a relatively uncommon form of AIHA, with studies noting the incidence of 7-8% among cases of AIHA. We experienced a patient, 46-year-old woman who was diagnosed having a very rare clinical presentation of mixed warm and cold antibody mediated Evans syndrome. She was treated with corticosteroid therapy only and has been maintaining a complete response for 15 weeks. 저자들은 혼합형의 자가면역성 용혈성 빈혈과 자가면역성 혈소판 감소증이 동시에 발생한 혼합형 Evans 증후군으로 진단하고 스테로이드 요법 후 혈액학적으로 회복된 상태로 15주가 지난 현재 steroid 5 mg/일 까지 감량한 상태에서 추적 관찰 치료중인 46세 여자 환자를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.
한상우,유진홍,권순석,김성훈,박지찬,홍은정,최경성,박용완,장준희,안지원,박유경,강지영,박상미,신완식 대한감염학회 2004 감염과 화학요법 Vol.36 No.5
We experienced a 25 year-old male patient with typhoid fever complicated with massive hemoptysis. Pulmonary complication in typhoid fever is very rare and to our knowledge, there has been no report of hemoptysis as a main cause of death with this disease. We herein report a rare case of typhoid fever.
韓·中·日 初中高校生의 體格과 最大成長發育年齡에 관한 硏究 : 1987年을 中心으로
박춘배,최중명,박순영 慶熙大學校 1990 論文集 Vol.19 No.-
On the basis of the presented data which took boy and girl students and their subjects in Korea, Japan and Republic of China n 1987, the authors intended to compare and analyze the physique-growths(body height and body weight) of the three nations' students from May 1 in 1989 to April, 30, 1990 with the application of the medians of Korea, Republic of China and Japan. The result are as follows : A. Physical growth and development 1. Body height(cm) In case of male students, Korean students are superior in their body heights to Japanese students when they are before the year 10, but from 10 to 20, both of nations' students are same. And them students of Republic of China are all inferior to those of Korea and Japan through all these ages. In case of girl students, Koreans are taller than Japanese and Repulic of China through all these ages. Chinese are inferior in their heights to Korean and Japanese through all these ages. The interchange ages of the body height occured in the both sexes of 9.5-12.5 in Korean, 9.5-12.5 in Republic of China and 9.0-12.0 in Japan. During this period, girls are taller than boys, but after this period boys are taller than girls, Maximum growth age per year for male in Korea is the ages 12-13(8.71cm) and these for female is the ages 11-12(6.90cm) of Korean students. 2. Body weight(kg) In case of male, Japan students show similar growing degrees through all the ages, and the students of Korea and Republis of chinese indicate a little lower degree than Japan. In case of female, the similar phenomena are showed. The interchange ages of the body weight occured in the both sexes of 9.0-13.0 in Korea, 105-13.5 in Republic of China, and 10.0-12.5 in Japan. The MGA per year for male is the ages 12-13(7.01kg) in Korea, 13-14(5.46kg) in Republic of China, and 11-12(5.5kg) in Japan, while for female is the ages 11-12(2.72kg) in Korea, 10-11 and 11-12(4.39kg) in Republic of China, and 11-12(4.39kg) in Republic of China, and 11-12(5.1kg) in Japan, respectively. B : Maximum growth age(M.G.A) Comparison growth ages of Korean, Republic of China and Japanese students are as follows. Kore : Body height : Male 12.33 Female 11.32 Body weight : Male 12.36 Female 11.61 R.O.C : Body heigt : Male 13.27 Female 10.69 Body weight : Male 13.52 Female 11.50 Japan : Body height : Male 12.28 Female 9.88 Body weight : Male 11.94 Female 11.13
박영춘,이동국,임정근,이상도,이형 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3
This study was performed to verify whether or not chronic anticonvulsants therapy(≥12 months ) is associated with peripheral nerve dysfunction in epileptics. Nerve conduction studies were done to 51 epileptics who had been taking long term anticonvulsants therapy over 12 months. The mean age of epileptics was 23 years, and was composed of 29 men and 22 women. The mean nerve conduction velocity(NCV) was not significantly different between epileptics and controls. Compared phenytoin or carbamazepine monotherapy group with controls, the NCV was not significantly different in two groups respectively. In epileptics, the mean NCV was not significantly different between phenytoin and carbamazepine monotherapy group. There was no significant relationship between NCV and duration of therapy with either phenytoin or carbamazepine. In epileptics with phenytoin combined therapy, the mean median sensory NCV was significantly delayed than in those with phenytoin monotherapy.
朴鍾哲,金昌榮,崔春鎬 大韓神經精神醫學會 1970 신경정신의학 Vol.9 No.1
The experiment was performed on mature white male rats, weighing between 180 gm and 240gm. The experimental animals were divided into A,B and C subgroups, which 200mg of sulful per kg emulsified in olive oil was given orally for 4 days, 7 days and 12 days respectively. The control groups was given olive in orally in the same amount and for the same periods. In both control and experimental groups 100μc of ??or 7μc of ??? was injected intraperitoneally on the 4th, 7th and 12 days respectively. The animals were sacrificed 18 hours after the injections. The following results were obtained. 1. In both A and B experimental subgroups, the seminal vesicles, testicles and adrenals, showed remarkable weight increase while the ??? uptakes in the same groups were mildly increased. In C experimental subgroup the weight of the organs was either slightly increased or decreased, while ??? uptakes was remarkably increased. 2. After sulfur adminstration the thyroidal follicles contained thick colloidal substance and their size was mildly enlarged. However, in comparison with the control group, the form of the glandullar cells was of more cuboidal. The adrenal cortex showed hypertrophic changes and the atrophy of the medulla was so severe that it could be hardly recognized. 3. In comparison with the control group, the tunica mucosa of the seminal vesicles had smaller folds and the superficial cuboidal cell layers was atrophic, the cytoplasm was scanty, and the nucleus remained in the center of the cells. 4. The testicles of the experimental subgroups, compared with those of the control groups showed atrophic changes in the spermatogonium and spermatocytic layers.
박치영,모성환,문철호,곽재정,김태종,전용준,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1995 The Medical Journal of Chosun University Vol.20 No.2
von Willebrand's disease (vWD) is the most common autosomal-dominant inherited disorder resulting from a quantitative or a qualitative defect of von Willebrand factor (vWF). The most diagnostic pattern is the combination of a prolonged bleeding time, a reduction in plasma vWF concentration, a parallel reduction in ristocetin cofactor activity, and reduced factor Ⅷ activity, In this case, ristocetin-induced platelet aggregation data were compatible with that of vWD. Bleeding times were prolonged over 4 minutes, vWF antigen levels were 45%. vWF ristocetin cofactor activities were 0~1% and factor Ⅷ levels were 31%, when compared to the normal control. We report the case of a family with vWD. characterized by a quantitative defect in vWF