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      • 영어의 전치사와 한국어의 후치사와의 대조연구

        이영헌,장태진,최용재,조학행 朝鮮大學校 師範大學 1976 師大論文集 Vol.7 No.-

        두 언어 사이의 대조연구는 그 방법론에서 우선 "주어진 두 언어를 각각 따로 기술하고 그 결과를 대조하여 다른 점을 발견해 내는 것"으로 되어 있다. 이 정의를 이 연구에 적용한다면 영어의 전치사에 대한 모든 기술을 해 놓고 그것과 상관되는 한국어의 어떤 형태를 또한 독자적으로 기술 해 놓은 다음에 이 두가지 서술들을 서로 대조해 보아야 한다. 그러나 이 연구에서는 오히려 그 과정을 반대로 하여 서로 대응되는 것들을 찾아 내고 그것들의 어떤 공통된 유형을 모색해 보려고 한다. 그 이유로서는 본 연구가 문법체계 전반에 걸친 대조가 아니고 극히 특정적인 일부분에 국한 된 것이며 대조의 대상들도 서로 선명히 대응되는 것들이 아니기 때문이다. 더구나 이 연구가 추구하는 부분에서는 한국어와 영어 사이에 아무런 유사성도 발견되지 아니 한 것 같고 오히려 상이점만이 두드러지게 나타나고 있기 때문이다. 그러므로 본 연구의 결과가 상이점의 나열에 그칠 수도 있으며 발견된 대응점의 기계적 서술에 그칠 수도 있다. 그러나 워낙 이 연구의 목적이 거기에 있는 이상 방법론의 새로운 적용은 여기에서만은 타당하다고 볼 수 있다. 물론 이 연구의 효용에 대하여서는 대조분석의 효용이라는 원칙적 문제에까지 소급하여 생각하지 아니 할 수 없으나. 대조분석이 갖는 많은 문제점에도 불구하고 상당히 희망적이다. 대조분석이 노리는 점은 항상 차이점 또는 상이점의 발견이지만, 이 연구는 어떤 기계적 대응관계를 찾으려는 것이기 때문에 그것이 직접 학습과 번역에 도움이 될 것이란 기대가 결코 지나치다고는 할 수 없을 것이다. 이 연구의 결과는 이미 약간 언급한 바와 같이 교제의 편찬을 위한 것이 아니고 단순히 영어학습자에게 전치사를 지도하는 데 있어서 우리말과 대응되는 점을 일깨워 줌으로서 영문국역에 어떤 기계적 대조에 가까운 색인을 주려는 것이다. 여기서 기계적이라고 함은 번역에 있어서 어느 정도의 정확성을 주려고 하는 의도를 나타낸 것이다. 다시 말하면 컴퓨터에 넣을 수 있을 정도로 일대일로 대응되는 색인은 기대할 수 까지는 없다는 것이다.

      • 흡입관에 부착된 디퓨저 효과에 대한 연구

        김도태,이행남,박길문,이덕구,설재림 朝鮮大學校 機械技術硏究所 2004 機械技術硏究 Vol.7 No.1

        The diffuser is used to get low pressure, and it has been applied to a lot of industry field like the heat engine, the fluid instrument power plant, the food industry, environment industry etc... because there are not any problem even it is mixed with kinds of liquid, gas, and solid. The flow characteristics in diffuser are investigated by prv and CFD. The experiment using PIV measurement for mixing pipe's flow characteristics acquired velocity distribution, .Condition : when mixing pipe's diameter ratio is 1:2.3, and the flux is Q₁ = 1.136 l/s, Q₂ = 1.706 l/s, Q₃ = 2.276 l/s . Based on the PIV and the CFD results, the flow characteristics in ejector are discussed, and it shows the validity of this study.

      • 심실중격결손증-치험 1예-

        조광현,우종수,황윤호,이양행,박철호,김종성,김철호,이경순,조영일,박태인 인제대학교 1985 仁濟醫學 Vol.6 No.4

        A successful treatment of infants and children with congenital heart defects depends upon several factors: diagnosis must be accurate, the operative technique, including techniques of perfusion and myocardial preservation, must be suited to the needs of patients and intensive cares, including accurate anesthesia, must be applied through all stages of investigation and treatment, i.e. before, during and after the operation. Recently we performed a open heart surgery successfully for a six-years old girl who had suffered from frequent upper respiratory tract infection and mild to moderate exertional dyspnea with congenital heart defects (ventricular septal defect, Kirklin type II, with patent foramen ovale). The operation and postoperative course were very smooth. And now we report this with review of literatures.

      • KCI등재

        수출입 컨테이너 장치장 배정을 위한 소프트웨어의 개발

        김갑환,김홍배,홍봉희,김기영,배종욱,최진오,김두열,이영기,박영만,박강태,손행대 한국경영과학회 1995 經營 科學 Vol.12 No.3

        The Pusan Container Terminal faces a rapid increase in berthing time of container ships as well as in waiting time of external trucks, which is due to an absolute lack of yard space. This research is focused on the development of a decision support system for the planning of the container terminal yard assignment so that the yard space would be utilized most effectively. Efforts should be given to the reasonable assignment of the yard storage and the dynamic adaptation to the ever changing environment. The software introduced here is based o the know-how of the field exports and its framework takes the approach of the hierarchical decision making.

      • KCI등재

        테트라사이클린系 抗生物質의 分析技法 開發 및 殘留調査에 關한 硏究

        Tae Haeng Cho(趙太行),Kwang Jick Lee(李光稙),Nam Sup Jin(秦南燮),Sun Namgoong(南宮琁),Jong Myung Park(朴鍾鳴),Mun Han Lee(李文漢) 한국예방수의학회 1993 예방수의학회지 Vol.17 No.3

        A method for the isolation and liquid chromatographic determination of tetracyclines (Oxytetracycline, OTC ; Tetracycline, TC; Chlortetracycline, CTC ; and Doxycycline, Doxy) in beef, pork and chicken samples is presented. Tetracyclines-fortified muscles(0.5g) were blended with octadecylsilyl(C₁₈) derivatized silica (2g). The C₁₈/muscle matrix was used to prepare a column that was washed with hexane(10ml) and then eluted with benzene(10ml) and 10ml of methanolic oxalic acid(0.01M oxalic acid in methanol). The method uses small volume of solvents, has a limited number of sample manipulation, and require no pH adjustment, making this method attractive when compared to classical isolation procedures for tetracyclines.

      • Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer

        Lee, Shee Eun,Hong, Seol Hee,Verma, Vivek,Lee, Youn Suhk,Duong, Tra-My Nu,Jeong, Kwangjoon,Uthaman, Saji,Sung, Young Chul,Lee, Jae-Tae,Park, In-Kyu,Min, Jung-Joon,Rhee, Joon Haeng TaylorFrancis 2016 Oncoimmunology Vol.5 No.2

        <P><B>ABSTRACT</B></P><P>Cervical cancer is a high-incidence female cancer most commonly caused by human papilloma virus (HPV) infection of the genital mucosa. Immunotherapy targeting HPV-derived tumor antigens (TAs) has been widely studied in animal models and in patients. Because the female genital tract is a portal for the entry of HPV and a highly compartmentalized system, the development of topical vaginal immunotherapy in an orthotopic cancer model would provide an ideal therapeutic. Thus, we examined whether flagellin, a potent mucosal immunomodulator, could be used as an adjuvant for a topical therapeutic vaccine for female genital cancer. Intravaginal (IVAG) co-administration of the E6/E7 peptides with flagellin resulted in tumor suppression and long-term survival of tumor-bearing mice. In contrast to IVAG vaccination, intranasal (IN) or subcutaneous (SC) immunization did not induce significant tumor suppression in the same model. The vaginal adjuvant effect of the flagellin was completely abolished in Toll-like receptor-5 (TLR5) knock-out mice. IVAG immunization with the E6/E7 peptides plus flagellin induced the accumulation of CD4<SUP>+</SUP> and CD8<SUP>+</SUP> cells and the expression of T cell activation-related genes in the draining genital lymph nodes (gLNs). The co-administered flagellin elicited antigen-specific IFNγ production in the gLNs and spleen. The intravaginally administered flagellin was found in association with CD11c<SUP>+</SUP> cells in the gLNs. Moreover, after immunization with a flagellin and the E6/E7 peptides, the TLR5 expression in gLN cells was significantly upregulated. These results suggest that flagellin serves as a potent vaginal adjuvant for a therapeutic peptide cancer vaccine through the activation of TLR5 signaling.</P>

      • SCISCIESCOPUS

        Monoclonal Antibodies against <i>Vibrio vulnificus</i> RtxA1 Elicit Protective Immunity through Distinct Mechanisms

        Lee, Tae Hee,Cha, Sun-Shin,Lee, Chang-Seop,Rhee, Joon Haeng,Chung, Kyung Min American Society for Microbiology 2014 Infection and immunity Vol.82 No.11

        <P><I>Vibrio vulnificus</I> causes rapidly progressing septicemia with an extremely high mortality rate (≥50%), even with aggressive antibiotic treatment. The bacteria secrete multifunctional autoprocessing repeats-in-toxin (MARTX) toxins, which are involved in the pathogenesis of Gram-negative <I>Vibrio</I> species. Recently, we reported that immunization with the C-terminal region of <I>V. vulnificus</I> RtxA1/MARTX<SUB>Vv</SUB>, RtxA1-C, elicits a protective immune response against <I>V. vulnificus</I> through a poorly defined mechanism. In this study, we generated a panel of new monoclonal antibodies (MAbs) against <I>V. vulnificus</I> RtxA1-C and investigated their protective efficacies and mechanisms in a mouse model of infection. Prophylactic administration of seven MAbs strongly protected mice against lethal <I>V. vulnificus</I> infection (more than 90% survival). Moreover, three of these MAbs (21RA, 24RA, and 47RA) demonstrated marked efficacy as postexposure therapy. Notably, 21RA was therapeutically effective against lethal <I>V. vulnificus</I> infection by a variety of routes. Using Fab fragments and a neutropenic mouse model, we showed that 21RA and 24RA mediate protection from <I>V. vulnificus</I> infection through an Fc-independent and/or neutrophil-independent pathway. In contrast, 47RA-mediated protection was dependent on its Fc region and was reduced to 50% in neutropenic mice compared with 21RA-mediated and 24RA-mediated protection. Bacteriological study indicated that 21RA appears to enhance the clearance of <I>V. vulnificus</I> from the blood. Overall, these studies suggest that humoral immunity controls <I>V. vulnificus</I> infection through at least two different mechanisms. Furthermore, our panel of MAbs could provide attractive candidates for the further development of immunoprophylaxis/therapeutics and other therapies against <I>V. vulnificus</I> that target the MARTX toxin.</P>

      • KCI등재

        抗生物質 amoxicillin 原料 및 salinomycin 添加劑의 安定性 調査

        Tae Haeng Cho(趙太行),Kwang Jick Lee(李光稙),Sun Namgoong(南宮旋),Jae Chin Lee(李在鎭) 한국예방수의학회 1994 예방수의학회지 Vol.18 No.2

        The amount of consumption of antibiotics including salinomycin and amoxicillin trihydrate has been growing day by day as a variety of disease occured in recent years. But the terms of validity of amoxicillin and salinomycin was not determined in Korea as yet. We examed the stability of amoxicillin trihydrate by checking the change of potency, pH, content of water and property under the ambient and stress condition (40℃, humidity 30~70%) and there was little change in potency, pH, content of water and property till the 30 months during the preservation time and salinomycin was same here so it will be possible to establish the terms of validity about 24 months in case of amoxicillin trihydrate and salinomycin feed additives.

      • KCI등재

        1993年度 動物用 抗生物質製劑의 國家檢定成績

        Tae Haeng Cho(趙太行),Kwang Jick Lee(李光植),Jae Jin Lee(李在鎭) 한국예방수의학회 1994 예방수의학회지 Vol.18 No.3

        This report was results to be analyzed for quality control to animal using antibiotics of 30,651 lots duing the periods of 1963 to 1993. Among them, 30,461 lots are passed and 190 lots rejected through national assay. The preparation forms of animal using antibiotics of total 15,981 lots examined for 7 years (1987~1993) were classified as feed additives 5,437(34.0%), injectables 4,322(27.0%) and soluble powders including oral suspensions 3,972(24.9%), respectively. Of the antibiotics of 15,981 lots, 1,278 lots(8.0%) were applied for raw materials, 879 lots(5.5%) as implantations for therapy of bovine mastitis and 93 lots(0.6%) as the other antibiotics. In 1993, 1,910 lots of animal using antibiotics were examined by regulation of national assay. Among them 1,887 lots are passed and 23 lots rejected through national assay. During the periods of 1985 to 1993, 20,140 lots of antibiotics were test by regulation of national assay. Among them, 190 lots were rejected by results of national assay. By the preparation forms, the soluble powders including the oral suspensions were highly rejected 66 lots, and injectables, feed additives, implantations and the others were orderly rejected, 52, 52, 18 and 2 lots, respectively By reason of the rejection, 152 of 190 lots were insufficient potency, 24 excessive humidity, 11 high pH and 3 adequate characteristic tests, respectively

      • SCOPUSKCI등재

        메네트리어병 국내 보고 16예의 임상적 고찰

        이종철,김영호,이미숙,이순진,손희정,강태욱,이준행,박동일,김재준,최규완,백승운,이풍렬,임윤정,장재권 대한소화기내시경학회 2000 Clinical Endoscopy Vol.21 No.6

        Background/Aims: Menetrier's disease is a poorly defined condition that is f unknown origin, characterized by giant folds in the stomach. The histoiogic fentures are foveolar hyperplasia and cystic dilatation of the gland. We presented the characteristic findings of Menetirer's disease in Korea with a review of literatures to understand the Menetirer's disease more precisely, Methods: The sixteen cases of Menetrier's disease was reported in Korea. We analyzed their age, sex, symptoms, signs, laboratory findings and treatments, retrospectively, Results: The average age was 46 years. There were 11 men and 4 women. The most common symptom was epigastric pain (94%). The most common sign were epigastric tenderness (69%) and pretibial pitting edema (63%). Patients were often associated with the hypoalbuminemia (73%). All patients showed hypertrophic folds on either gastrofiberscopy or upper gastrointestinal series, All patients showed foveolar hyperplasia histologically. Three patients were operated to control a massive upper gastrointesinal bleeding. Two patients were operated to control the intractable edema. Two patients were operated to exclude gastrie malignancy, Conclusions: Menetrier's disease showed broad clinical features such as epigastric pain, hypoalbuminemia, massive hematemesis and mimicking gastric malignancy. The giant gastric folds and foveolar hyperplasia were the most commom and important findings in the Menetrier's disease.

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