생약제제인 이공산(異功散)의 Cisplatin 유도 신장독성 보호 및 항산화 효과

Lee, Kyung-Tae,Ahn, Kyoo-Seok,Chang, Sung-Goo,Oh, Soo-Myung,Jung, Jee-Chang 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Kyung-Tae Lee, Kyoo-Seok Ahn¹, Sung-Goo Chang², Soo-Myung Oh²and Jee-Chang Jung²¹College of Pharmacy, ²Oriental Medicine and ³College of Medicine, and East-West Medical Reserch Institute, Kyung Hee University, Seoul, Korea. Preventive and Antioxidative Effects of Crude Drug Preparation(E-kong-san) on Cisplatin Induced Nephrotoxicity. Proceedings of International Symposium on East-West Medicine, Seoul. 201-211, 1999. -Nephroprotective effects of a crude drug-prearation (E-kong-san) were determined from cisplatin on rabbit kidney proximal tubule and human renal cortical cells by MTT assays and sustained glucose consumption on ciplatin-induced human renal cortical tissue. Levels of creatinine and blood ure nitrogen(BUN) in serum after administration of cisplatin(0.75mg/kg,i.p.) to E-kong-san(0.75g/kg/day,p.o.)-pretreated rats were markedly lower compared to those of cisplatin-treated rats. Moreover, the administration of E-kong-san significantly inhibited the loss of body weight of cisplatin injected rts. These findings suggest that E-kong-san on the cisplatin induced nephrotoxicity led us to investigate whether the effect of this water extract was a result of anti-oxidation. E-kong-san showed strong free radical scavenger activities on 1,1-dipheny1-2picrylhydrazil(DPPH) radical and xanthine/xanthine oxidase(XOD) generated superoxide anion radical(O2-). We further studied the effects of E-kong-san on lipid peroxidation in rat liver microsomes induced by enzymatic and nonenzymatic methods. E-kong-san exhibited significant inhibition on both ascorbic acid/Fe2+and ADP/NADPH/Fe3+ induced lipid peroxidation in rat liver microsomes. Based on these results, we suggest that-E-kong-san attenuate the cisplatin induced cytotoxicity and its mechanism can be eplained by antioxidant.

太谿穴의 臨床 活用에 대한 文獻考察

구성태,송문영,강정묵,김용명,박보라,이은석,홍정아,김경식,손인철 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Literally, the mean of Tae-gye is highest brook. And on the basis of the acupuncture theory, Tae-gye point is the Soo earth point and source point of the Kidney Channel as well. In addition, Tae-gye point is one of the Yang-Returning Nine points. We were trying to study bibliographically on the Tae-gye point because Tae-gye point can be used very broadly across the symptoms in the theoretical aspect described above. As a results, we found out that according to the classical books of acupuncture, Tae-gye point is entering point of the Meridian Water as a source point and can be used at both Kidney-Sufficient Syndrom and Kidney-Deficient Syndrom. And Tae-gye can be applied to the disease of kidney or bladder that is urogenital symtoms, Also, Tae-gye is an useful option of tooth-ache, asthma, indigestion, constipation, edema etc whose cause is related with decrease of Kidney ki.

정수처리공정상 염소소독부산물형성에 미치는 오존의 영향

성낙창,박현석,이성식,이용희,이종팔,윤태경 한국환경과학회 2004 한국환경과학회지 Vol.13 No.1

The effect of ozone on the formation and the removal of disinfection byproducts(DBPs) of chlorination process was studied to elucidate the performance of water treatment process. The samples of raw water, prechlorination process, and preozonation process were analyzed quantitatively according to the Standard Methods for the Examination of drinking water. As a result, most of total trihalomethanes(THMs) which were formed in prechlorine treatment process was not removed in the preozonation process. Most of haloacetic acids(HAAs), haloacetonitriles(HANs), and chloral hydrate(CH) was removed in sedimentation and biological activated carbon(BAC) filtration processes. However, DBPs were increased more or less by postchlorine step. In particular, the formation of THMs and HAAs depends on ozone more than chlorine, but, the formation of HANs and CH depends on chlorine more than ozone. The seasonal variation of DBPs concentration for the year needs to be investigated to study the temperature effect because DBPs strongly depend on temperature among various efficient factors.

비지니스 프로세스 리엔지니어링 : 선택이 아니라 필수

成泰景 京畿大學校 韓國産業經濟硏究所 1994 産業硏究 Vol.5 No.-

또 하나의 사회 : 광고에 표현된 한국적 vs 서구적 인간관계

성영신,허태균,김보경,박정선 한국방송광고공사 2006 광고연구 Vol.0 No.73

본 연구에서는 광고 비주얼에 표현된 인간관계의 문화적 차이에 따라 소비자의 심리반응이 어떻게 다른지 비교해보았다. 한국적(서구적) 인간관계를 부모 - 자녀, 온가족, 부부, 연인의 네 가지 관계유형으로 나누어 이를 묘사한 인쇄 광고물을 제작한 후, 소비자의 심리반응을 fMRI(기능성 자기 공명 영상) 기법과 설문조사 방법으로 측정하였다. 소비자는 무의식적인 fMRI 반응과 의식적인 반응 모두에서 한국적 광고보다는 서구적 광고에서 더 좋은 반응을 보였다. 특히, 광고효과의 경우 연인광고를 제외한 다른 인간관계 광고들 모두에서 서구적 광고가 더 효과적인 것으로 나타났다. 이렇게 전반적으로 서구적 인간관계 광고가 강한 신경 반응과 긍정적 광고효과를 수반하는 것은 한국인들이 상당히 서구적인 가치관을 가지고 있으며 이를 지향한다는 최근 연구결과와 일치한다. 끝으로, 본 연구결과가 갖는 크리에이티브 측면의 시사점을 제안하였다. 유형별 차이로는 연인이나 부부 광고는 무의식적 반응이나 감정반응에서 한국적인 광고가 보다 긍정적인 결과를 보이는 반면, 가족이 등장하는 광고에서는 서구적 광고가 더 긍정적인것으로 나타났는데, 이는 실험참가자가 인간관계 유형에 따라 다른 문화적 인식과 지향점을 갖으며, 이것이 광고반응에 영향을 미치고 있음을 보여준다. The purpose of the present research was to compare the psychological effects of the Korean human relations advertise(KHRA) to those of the Western human relations advertise(WHRA). The consumers’ physiological and conscious responses to the ads including visual images of Korean(vs. Western) four types of relationship - parentschildren, multi-generation family, married couple, and romantic couple - were measured by fMRI(functional Magnetic Resonance Imaging) and survey. The results revealed that consumers tend to respond more strongly and better to the WHRAs than the KHRAs. Especially, in terms of advertising impacts, the WHRAs were more effective than the KHRAs across the ads of all the three human relations except the ads of romantic couples. These results are consistent with the recent research findings suggesting the Westernizing sifts of Korean cultural values. Finally, they were discussed in the view of the implications of advertising creative tips.

테니스 선수의 체력 요인 분석

성영호,김경호,최태훈 龍仁大學校 體育科學硏究所 1999 體育科學硏究論叢 Vol.9 No.1

This research intends to examine the physical fitness factor of high school and university mate tennis players. Eight tests were performed and the factor analysis was used to examine the fitness level. Therefore, we will now discuss this research's conclusion. Within the factor structure, three factors for high school males(strength, endurance, agility), and four factors for university males(endurance, agility, strength, flexibility) were sampled and we can see that university athletes are more specialized than high school athletes. Therefore, we can see that for high school students, strength is an important factor, while for university students, endurance is an important factor.

Treatment of Radioactive Liquid Waste by the Forced-AirCirculation System

Tae-κuk Kim,IL Sik Kang,Jong-Sik Shon,Young-Gerl Ryu,Won-Hyuk Jang,Sang-Min Bae,Young-Yong Ji,Dae-Seok Hong,Kyung-Kil Kwak 한국방사성폐기물학회 2011 한국방사성폐기물학회 학술논문요약집 Vol.9 No.2

한국형 우울장애 약물치료 알고리듬 (Ⅳ) : 우울장애의 아형 및 부작용에 따른 항우울제의 선택과 여성우울장애에서의 치료전략

전현태,이상열,김원,민경준,박원명,서정석,석정호,송해철,전덕인,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : In 2002, the Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) was published, but there has been a need for a guideline about detailed issues of depressive disorder. We revised KMAP-MDD andreestablished Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. Methods : A questionnaire had been developed by the executive committee for KMAP-DD. The review committee consisted of 101 experienced psychiatrists. From the total of 22 questions in the questionnaire, 7 questions were evaluated for these subjects . We classified the expert opinions to 3 categories according to its confidence interval; first, second and third line. Results : SSRI and venlafaxine were the first line antidepressants (AD) for atypical and melancholic depression. For dysthymic disorder and minor depressive disorder, SSRI was recommended as the first line medications. Only AD medications was a preferred initial strategy for treating premenstrual dysphoric disorder, mild to moderate and severe non-psychotic postpartum depression. In severe psychotic postpartum depression, combination therapy of AD and atypical antipsychotics was the treatment of choice. SSRI was preferred when considering sedation, anticholinergic and cardiovascular adverse effects. Also, experts recommended mirtazapine against gastrointestinal adverse effects and bupropion in avoiding sexual dysfunction. Conclusion : These results suggest that clinicians have to consider both clinical situations and drug adverse effects in the choice of antidepressant medications.

상·하악골 동시이동술에 관한 연구

이상한,최태호,서혜경 慶北大學校 齒科大學 1987 慶北齒大論文集 Vol.4 No.1

The need for two-jaw surgery is based on the facial and occlusal deformity present, and the simultaneous mobilization and repositioning of the entire maxilla and mandible has become a common practice in maxillofacial surgery. The authors obtained the following results from the two patients with the maxillofacial deformities. The results were as follows: 1. The two Angle's Class Ⅲ patients with maxillary A-P deficiency and mandibular excess were treated on the simultaneous repositioning of maxilla and mandible. 2. In each case, the LeFort I osteotomy with the dagittal split osteotomy and the LeFort I osteotomy with the vertical osteotomy were performed on one-stage operation. 3. The time of operation was 6.5 hours and 4.67 hours in each case. 4. The duration of the intermaxillary fixation was 8 weeks and 7 weeks in each case. 5. The phenomenon of the relapse were not showed until the intermaxillary fixations were removed.

상아질의 표면 ZOE처리가 글래스아이오노머 시멘트의 전단강도에 미치는 영향에 관한 연구

김경덕,정태성 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.2

The purpose of this study was to asses the shear bond strengths of 3 types of glass ionomer cement and 1 type of composite resin to dentinal surface with or without ZOE pre-treatment. 80 extracted tooth specimens are divided into two groups : the control group (40 specimens) is ZOE pretreated during 24 hours before bonding procedure. Shear bond strengths were measured with universal testing machine (Instron, Model 4301) and statistically processed by ANOVA and t-test. The results were as follows : 1. Bond strength of the ZOE treated experimental group showed lower than the control group, except chemical cured glass ionomer cement(p<0.05). 2. After ZOE surface treatment, the bond strength of composite resin was superior than glass ionomer cement and all experimental group was decreased(p<0.05). 3. It has nothing to do with ZOE surface treatment, that chemical curing glass ionomer cement was showed lowest bond strength.