Basic upper lip thickness에 따른 교정치료 후 입술 이동량의 차이

박선형,박성헌,조영문,김정훈 대한치과교정학회 2002 대한치과교정학회지 Vol.32 No.5

교정치료 후 연조직의 변화가 나타난다. 특히, 하안면부위에 많은 변화를 일으키게 되며, 대표적으로 입술은 치아이동량의 60∼70%정도 이동한다고 알려져 있다. 하지만, 이동량은 개인마다 그 양상이 다양하다. 본 연구는 환자의 입술두께에 따라 연조직이동양상에 차이가 있는지 여부를 조사하는데 그 목적이 있다. 발치를 동반한 교정치료를 받은 성인환자를 대상으로 basic upper lip thickness에 따라 환자를 분류한 결과, 두께가 얇은 군(group 1)에서 치료 후 연조직 변화에 영향을 미치는 요인으로는 mentolabial angle와 하순의 변화간에 음의 상관관계를 보였다. 두께가 평균인 군(group 2)에서 상순의 변화에 영향을 미치는 요소로는 상악전치의 변화, 하악전치의 변화, 하순의 변화, nasolabial angle의 변화로 나타났으며, 하순의 변화에 영향을 미치는 요소로는 상순의 변화, 상악전치의 변화, 하악전치의 변화로 나타났다. 두께가 두꺼운 군(group 3)에서는 상순, 하순의 변화는 전치위치의 변화나 연조직변화와는 관련없음으로 관찰되었다. After orthodontic treatment, there are several changes in soft tissue porfile. Changes appear at lower anterior facial profile area, especially upper and lower lip. But there are many individual variations in the pattern of changes. So, this study was conducted to find out that the basic upper lip thickness could be one of the factors that could influence the treatment results. The samples were composed of 43 adult patients who had their 4 first premolars extracted. Groups were classified by their basic lip thickness. In group 1(thin upper lip group), there was negative relationship between mentolabial angle and lower lip change. In group 2(average lip thickness group), upper lip change was related to upper incisor change, lower incisor change, lower lip change and nasokabial angle change. And lower lip change was related to upper lip change, upper incisor change, lower lip change. In group 3(thick upper lip group), there was no relation between both lip change and other variables.

전압의존성 칼슘채널 β3 subunit 유전자 변이종의 클로닝과 흰쥐 뇌에서의 발현

김형래,김현,박선화,김현,박선화,김동연,서영석,서영석 대한해부학회 1998 Anatomy & Cell Biology Vol.31 No.2

해부-신경생리학적 Monitoring을 통한 뇌중심 영역수술의 고찰

박명찬,박철형,김형일,이정청,김동찬,송희선 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.6

In the surgery of central area, idenwg the motor cortex in front of central sulcus is imperative to prevent loss of motor function. Twenty five patients with tumors or intractable epilepsy near the central sulcus were operated on at the Department of Neurosurgery of Chonbuk National University Hospital, from September. 1991 to December 1993. An estimated localization of lesions was performed with Callosal Grid System, which is a methodolgy made available by the development of high quality of magnetic resonance imaging, digital subtraction angiography and high resolution computerized tomography. This system allowed us to be oriented to the motor cortex as well as permitted assessment of the extent of resection. This was further delineated by direct electrical stimulation, which confirmed the functional motor cortex and made it possible to maximized the tumor resection near and in the motor cortex The combination of direct cortical stimulation (functional mapping) and the use of the Callosal Grid System (anatomical mapping) allowed us to idene the spatial relationship between them as well as to maximize the tumor resection in most cases without injury to the central area, so that the better outcome is guaranted.

Anti-idiotypic 항체가 Hybridoma 세포의 Anti-DNA 항체 합성을 조절하는 기전

박선,박정수,김형일,주민경,장영주,윤정구,김영태 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1

The regulatory mechanism of anti-idiotypic antibody(anti-id Ab) in the immune response is not fully understood. It has been reported that anti-id Ab suppresses Ab production of lymphocytes or hybridoma cells in vitro, but it does not affect the proliferation of cells or Ab secretion. We investigated whether or not polyclonal anti-id Ab regulates the production of anti-DNA Ab(lgG2a) in hybridoma cells. In addition, the effects of anti-id Ab on the proliferation of cells and on the transcription levels of lg genes were studied to elucidate the cellular and molecular mechanisms for regulation of anti-DNA Ab production in hybridoma cells. The treatment of hybridoma cells with anti-id Ab resulted in an increase in the number of cells producing anti-DNA Ab. However, there was no significant difference in the proliferation rate and mRNA levels of Ig genes between hybridoma cells treated with anti-id Ab, and those treated with normal rabbit serum. These results and our previous data suggest that the number of hybridoma cells producing anti-DNA Ab by anti-id Ab is not directly related with the rate of proliferation of the cells. Furthermore, it appears that the number of hybridoma cells producing IgG class anti-DNA Ab is increased by anti-id Ab, whereas the number of hybridoma cells producing IgM class anti-DNA Ab is down-regulated by anti-id Ab.

BCG와 levamisole 투여가 canine parvovirus subunit antigen에 대한 기니픽의 면역반응에 미치는 영향

박선경,장경수,박종현,전무형 충남대학교 수의과대학 동물의과학연구소 1995 動物醫科學硏究誌 Vol.3 No.-

To investigate the effects of priming with BCG and levamisole on the immune responses of the guinea pigs inoculated with CPV-intact antigen(CPV-IA) and recombinant CPV-subunit antigen(CPV-SA), hemagglutination inhibition(HI) test and leucocytes migration inhibition(LMI) test were applied for measurement of antibody and cell-mediated responses, respectively. 1. The minimal concentration of CPV-IA and CPV-SA to evoke HI antibody in guinea pig was 1,000 HAU and 2,000 HAU, respectively. 2. As the effects of priming with BCG and levamisole were examined by HI test, double primings showed higer HI titers than single priming and the groups primed with levamisole showed higher HI antibody titers than groups primed with BCG. All of groups primed with BCG and levamisole revealed prominantly higher HI titers than the non-primed group. 3. The optimal conditions for LMI were 64 HAU for antigens, 1×10^6 cell/ml for the concentration of leucocyte and 2 hrs for antigen-leucocyte reaction time. 4. When the cellular immune responses for the guinea pig inoculated with CPV-IA were examined by LMI test, BCG-primed groups showed significantly higher %LMI than the levamisole-primed group(P<0.05). Double primings revealed a tendency of higher %LMI than single priming, but statistically not significant. All of primed groups showed significantly higher %LMI than non-primed groups (P<0.001). 5. When the cellular immune responses for the guinea pig inoculated with CPV-SA were examined by LMI test, BCG-primed groups showed a tendency of higher %LMI than the levamisole-primed groups and double primings revealed higher %LMI than single priming in both of BCG and levamisole. All of priming groups showed significantly higher %LMI than the non-primed groups (P<0.001).

형광 in situ hybridization 방법에 의한 c-myc 유전자의 전위 및 증폭에 관한 연구

김경채,박선화,김강련,김미영,전용혁 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

먹는 물에서의 비소 검출에 관한 연구 : ICP-USN법과 ICP-VGA법의 비교 Comparison ICP-USN method ICP-VGA method

박경선,김형석,조인성 慶熙大學校 地球環境硏究所 1999 지구환경논문집 Vol.10 No.-

Abstract The analysis of arsenic in drinking water with ICP-USN method and ICP-VGA method was studied. In USN method, wavelength of 193.696nm was used and in VGA method, 228.812nm was used. The values of arsenic of same sample in each method, MDL, RPD, recovery, accuracy and precision were studied. The values of 14 sample of drinking water were within 0.05ppm or were not detected. But in one sample high value of 0.044ppm was detected. MDL of USN was 0.013ppm and MDL of VGA was 0.0004ppm. This results showed lower MDL of VGA but RPD of USN was better than VGA. Recovery of two methods was same, but accuracy and precision of USN were better than VGA. Therefore ICP-VGA method could be used according to this result(MDL) when arsenic trace element detection in drinking water should be achieved.

치아 우식증의 조기 진단을 위한 QLF-D 개발

박형주,김종수,유승훈,신지선 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

QLF-D system composed with DSLR(digital single-lens reflex) camera, and the images of natural enamel caries and artificial caries was developed from 2 days to 14 days captured by QLF-D system. The correlation between lesion depth of the polarized microscope and luminosity ratio of QLF-D image was analyzed and the results were summarized as follows: 1. The Pearson correlation value between the lesion depth of polarized microscope images and luminosity ratio of QLF-D images was 0.969(p<0.01). 2. From Regression analysis of lesion depth from polarized image by demineralized period, the equation was y = 8.67x - 1.16(p<0.05). 3. From Regression analysis of luminosity ratio from QLF-D image by demineralized period, the equation was y = 3.53x + 6.42(p<0.05). From the results, QLF-D system can detect the enamel caries at the very early stage and can monitor the progression of demineralization and remineralization. For the convenient use of QLF-D system in the laboratory, the image analysing software was needed to analyze of interest site of enamel caries lesion. 저자는 DSLR(digital single-lens reflex) 카메라를 이용한 QLF-D 시스템을 고안하여, 사람의 유구치에 자연 발생된 법 랑질 초기 우식증을 관찰하고, 유구치 법랑질 시편을 대상으로 2일부터 14일까지 인공 탈회시킨 후 탈회 기간에 따른 상관관 계를 편광 현미경 소견과 비교 분석한 결과 다음과 같은 결과를 얻었다. 1. 탈회 기간에 따른 편광 현미경 상의 병소 깊이와 QLF-D 영상의 광밀도 값 비율 간의 피어슨 상관 계수는 0.969였다 (p<0.01). 2. 편광현미경에서 측정된 병소 깊이의 탈회 기간에 대한 회귀분석 결과 y=8.67x-1.16의 회귀 방정식이 산출되었다 (p<0.05). 3. QLF-D 영상에서 측정된 광도값 비율의 탈회 기간에 대한 회귀분석 결과 y=3.53x+6.42의 회귀 방정식이 산출되었다 (p<0.05).

전산화에 의한 중환자실 환자의 임상적 고찰

박선규,조형상 중앙대부설한국의과학연구소 1986 한국의과학 Vol.18 No.3

전방경추부 응합술시 단피질 나사못과 양피질 나사못의 비교연구

박형천,윤승환,박현선,김은영 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.5