남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

전문 문서 개념을 사용한 지식 미디어 시스템에 관한 연구

손영수,조정래,배상현 한국공작기계학회 1996 한국생산제조학회지 Vol.5 No.4

The knowledge of the specialized fields has seen changed rapidly in the both side of quantity and quality. A hyper media as a knowledge based system is so fixed in the linked media in mutual that we couldn't tell it information provision with the view of users. In this paper, we propose the way of offering intellectual and flexible information which is the same with demand in the side of user, selecting, searching and composing the hypertext at the point of user's view through the design of knowledge media system. Three concepts are used in order to challenge the knowledge media system : special document, agent system and ontology. The special document is a knowledge using special fields. The agent system is a homogeneous controller that operates on an application to ensure that its activities are coordinated with those of the others within the community, providing a uniform control mechanism. Finally, ontology is a language for exchanging knowledgement, which is a message exchanged among agents to ensure the proper interaction among them. The combination of these three concepts is used to design the prototype of knowledge media system.

中學生들의 問題와 必要에 關한 硏究

金秀子,孫榮子 이화여자대학교 사범대학 교육심리학과 1964 心理硏究 Vol.- No.5

레이저 인터페로메타를 이용한 드릴링 머신의 틸팅에 관한 연구

이승수,손영지,장성규,전언찬 동아대학교 공과대학부설 생산기술연구소 1996 生産技術硏究所硏究論文集 Vol.1 No.2

This paper describes tilt angle measurement method. This method measures tilt angle of drilling machine using laser interferometer with simple sliding linear bearing. Measurement method is next orders. First, measurement position is considered pointed contact of two probes. And revolution of drill axis deliver pointed contact of probe. Second, so laser interferometer attach on sliding linear bearing, moving of probe influence laser reflector. And laser program displays this vibration of laser reflector. Namely, this vibration is tilt factor. A lot of error factor have an effect on accuracy to measurement of linear, angular, and so on. But this paper ignores some error factor, because these error festor is very smaller than tilt angle factor which we had been measuring values.

골격성 Ⅲ급 부정교합자의 치성보상과 두개안면골격의 상관관계에 관한 연구

전영진,박수병,손우성 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.2

본 연구는 골격성 III급 부정교합자에서 상하악절치의 치성보상 양상과 골격형태 사이의 상관관계를 규명하기 위해 시행되었다. 정상교합자 59명, 미약한 골격성 III급 부정교합자 91명 그리고 심한 골격성 III급 부정교합자 58명을 연구대상으로 선정하였으며 특히 미약한 골격성 III급 부정교합자는 전치부 반대교합의 유무에 따라 반대교합이 없는 군과 반대교합군으로 세분하여 연구하였다. 측모두부방사선규격사진을 15개의 골격형태 계측항목과 16개의 상하악절치 경사도 및 위치 계측항목으로 분석한 뒤 통계 처리하여 다음과 같은 결과를 얻었다. 1. 각 군의 상하악 전치부 치성보상 양상을 보면 II-B군에 비해 II-A군과 III군의 상악 중절치는 순측경사 되어 있으며 II-A군이 III군 보다 크게 순측경사 되어 있었다. 하악절치는 II-A군과 II-B군에 비해 III군이 설측경사 되었으며 II-A군과 II-B군의 차이는 없었다. 2. II-A군과 II-B군 사이의 수직적인 골격형태 차이는 크지 않았고 하악절치 보다는 상악절치 위치 및 경사도에서 큰 차이를 보였다. 3. II-A군의 하악절치와 II-B군의 상악절치 계측항목이 골격형태와 상관성이 높았으며 특히 하악절치 계측항목중에서는 ∠IMPA, ∠FMIA, 상악절치 계측항목중에서는 ∠U1-FH, ∠U1-SN이 높은 상관성을 보였다. 4. 하악절치 계측항목중 ∠IMPA, ∠FMIA는 모든 군에서 골격형태와 높은 상관성을 보였다. 상악절치 계측항목중에서는 ∠U1-SN, ∠U1-FH, U1-facial plane(mm)이 다른 계측 항목에 비해 상관성이 높았다. This investigation was designed to analyze the degree of dental compensation according to horizontal components of craniofacial skeleton and to investigate correlation between dental compensation and craniofacial pattern in skeletal class III malocclusion. The material selected for this study consisted of standard lateral cephalogram of 59 subjects in normal occlusion group, 91 subjects in mild skeletal class III malocclusion group and 58 subjects in severe skeletal class III malocclusion group, The mild skeletal class III malocclusion group was divided into two groups, one was class III malocclusion without anterior crossbite group and the other was class III malocclusion with anterior crossbite group. 1. Mild skeletal class III malocclusion without anterior crossbite group showed the most labial inclination of upper incisors, followed by severe skeletal class III malocclusion group and mild skeletal class III malocclusion with anterior crossbite group, the latter showing the least. The amount of lingual inclination of lower incisors was the largest in severe skeletal class III malocclusion group, and there was no statistically significant difference between mild skeletal class III malocclusion without anterior crossbite group and mild skeletal class III malocclusion with anterior crossbite group. 2. There were little differences in vertical skeletal structure between mild skeletal class III malocclusion without anterior crossbite group and mild skeletal class III malocclusion with anterior crossbite group, they showed statistically significant differences in the upper incisors measurements. 3. The measurements of lower incisors in mild skeletal class III malocclusion without anterior crossbite group and upper incisors in mild skeletal class III maloclusion with anterior crossbite group represented a high correlation with skeletal structure. Especially, ∠IMPA and ∠FMIA of lower incisor measurements, and ∠U1-FH, ∠U1-SN of upper incisor measurements showed high correlation with skeletal structure in each group. 4. ∠IMPA and ∠FMIA of lower incisor measurements showed high correlation with skeletal structure in all groups. ∠U1-FH, ∠U1-SN and U1-facial plane(mm) of upper incisor measurements represented higher correlation with skeletal structure than any other upper incisor measurements.

생물방제균 Bacillus subtilis YB-70이 생산하는 항진균성 항생물질의 분리 및 구조결정

김용수,손종근,문동철,김상달 영남대학교 약품개발연구소 1997 영남대학교 약품개발연구소 연구업적집 Vol.7 No.-

인삼근부균 Fusarium solani의 생육을 강력히 저해하는 생물방제균을 저병해 인삼경작지 근권토양에서 분리, 선발하여 Bacillus subtilis로 동정한 바 있고, 이 생물방제균 B. subtilis YB-70의 식물근부균 F. solani의 생육에 대한 길항기작이 항진균성 항생물질에 기인된다는 사실을 배양생산물의 분자량별 활성도 검증, 열처리에 의한 잔존 활성도 측정 등에 의해 열에 강한 저분자성 항생물질로 재확인하였고 in vivo test에서도 F.solani에 의한 근부병을 강력히 억제할 수 있음을 하였다. 생물방제균 Bacillus subtilis YB-70이 생산하는 항진균성 항생물질을 pH 침전, 용매추출, silica gel chromatography, LH-20 column chromatography 등을 통해 항생물질 YBS-1A, B로 분리, 정제 할 수 있었으며, 이 물질의 구조를 MS, NMR, amino acid analysis로 추정해 본 결과 YBS-1A는 5종 7개의 amino 산으로 구성된 itulin A 계열 항생물질로 규명되었으며, YBS-1B는 7종 11개의 amino 산으로 구성된 분자량 1,500정도의 itulin A 보다 좀 더 큰 항생물질로 추정되었다. A potential biocontrol bacterium, YB-70 was isolated from a rhizosphere in suppressive soil and identified as strain of Bacillus subtilis. In several biochemical and in vitro antibiosis tests on Fusarium solani with the culture filterates from B. subtilis YB-70, we found that antifungal mechanism of B. subtilis YB-70 was mediated by antibiotic substances produced from the bacterium. These antifungal substances were appeared to be beat-resistanl, micromolecular, and ethyl alcohol soluble. Antifungal agents produced by B. subtilis YB-70 showed strong inhibition against root-rotting fungi F. solani in in vivo pot test. An antifungal substance, YBS-1s, was purified from the culture broth of B. subtilis YB-70 by isoelectronic precipitation, silica gel column chromatography and Sephadex LH-20 column chromatography. Three antifungal agents were isolated from the culture broth of B. subtilis YB-70. Various instrumental analysis by Fab-MASS, ¹H-NMR, ¹³C-NMR, DEPT, and amino acid analyzet revealed that the YBS-1A was a peptide antibiotics of iturin class containing seven amino acids from five different groups, and the other(YBS-1B) was an analogue of iturin class containing seven amino acids from five different groups, and the other(YBS-1B) was an analogue of iturin group composed of 11 amino acids with larger molecular weight of about 1,500 dalton, which was lager than that of iturin A.

인산용액의 농도 및 적용시간 차이에 따른 상아질 표면의 형태적 변화

김명수,온영석,이광원,손호현 大韓齒科保存學會 1998 Restorative Dentistry & Endodontics Vol.23 No.1

The depth and patterns of demineralization according to the difference in concentration and application time of phosphoric acid were observed through the transmission electron microscope, and shear bond strengths to the acid-conditioned dentin were then measured and compared with the TEM results. To investigate the influence of polymer addition into the phosphoric acid and the effect of difference in concentration and application time of the acid, the specimens were randomly divided into 9 groups. Among the specimens, the exposed dentin surfaces were acid-conditioned with 10% polymer-thickened phosphoric acid(All Bond 2, Bisco, U.S.A.) and aqueous 10%, 20%, 30%, 40% phosphoric acid for 20 seconds, The rest of the specimens were acid-conditioned with 10% phosphoric acid for 15s, 30s, 60s, 120s respectively. The specimens were immersed in 4% glutaraldehyde in 0.1M sodium cacodylate buffer and postfixed with 1% osmium tetroxide without decalcification and then observed under a JEOL Transmission Electron Microscope(JEM 1200 EXⅡ,Japan). After the specimens were acid-conditioned as the above, primer and adhesive resin were applied to blot-dried dentin and shear bond strengths were then measured and analysed. The results were as follows : 1. The intertubular demineralization depth of 4.0-5.0㎛ in 10% polymer-thickened phosphoric acid gels was similar or slightly deeper than that of 4.0-4.5㎛ in aqueous 10% phosphoric acid solution. 2. The intertubular demineralization depth of aqueous 20%, 30% and 40% phosphoric acid solution was 6.5-7.0㎛, 6.5-7.5㎛ and 9.0-15.0㎛ respectively. It showed that the depth of dentin demineralization is partly related to the concentration of phosphoric acid solution. 3. The intertubular demineralization depth of aqueous 10% phosphoric acid solution in application time for 15s, 30s, 60s and 120s was 2.5-3.0㎛, 4.0-6.0㎛, 6.5-7.0㎛ and 8.5-14.0㎛ respectively. It showed that the depth of dentin demineralization is directly related tothe application time of phosphoric acid solution. 4. The partially demineralized dentin layer between demineralized collagen layer and unaffected dentin was showed to a width of 0.5-1.0㎛ in lower concentration groups treated with aqueous 10% phosphoric acid for 20s, 60s, 120s and 20% phosphoric acid for 20s. 5. The demineralization effect at the border of intertubular-peritubular junction was less evident than that in the peritubular and intertubular dentin. The collagen fibers in the intertubular dentin had a random orientation, whereas those that lined the tubules were circumferentially aligned. The cross-linkage of dentinal collagen in demineralized collagen layer was clearly seen. 6. A statistically significant difference of bond strengths according to the difference in phosphoric acid concentration did not exist among the groups treated with 10%, 20%, 30% and 40% acid solution (P>0.05). However, bond strengths to the treated dentin with 10% phosphoric acid solution for 30s were significantly higher than that for 120s (P<0.05).

중금속 제거 및 pH 상승을 위한 폐달걀껍질의 재활용

조영수,최영락,손희정,김은호 東亞大學校生命資源科學大學附設 農業資源硏究所 1997 農業生命資援硏究 Vol.6 No.1

In the present, batch test was conducted to evaluate the neutralization and adsorption of heavy metals from wastewater using waste egg shells. Neutralization and removal rate of heavy metals were excellent in the increase of waste concrete amounts and a small size. It seemed that adsorption efficiencies of heavy metals were influenced by solubility. As a result on the experiments of Freundlich isotherm, the adsorption capacities(k) were Cr 3.11, Cu 2.61, Mn 3.02 and Pb 0.95, respectively and the adsorption intensities(1/n) were Cr 0.35, Cu 0.44, Mn 0.4 and Pb 0.41, respectively. In view of these results, it showed that wastes containing the similar compositions as waste egg shells could utilize the neutralization and adsorption of heavy metals in wastewater.

슬라이딩 섹터에 근거한 제어기 설계

배상현,손영수,한종길 조선대학교 전자정보통신연구소 2001 電子情報通信硏究所論文誌 Vol.4 No.2

A sliding sector is defined as a subset the state space, inside which some norm of state decreases with zero control input. The variable structure controller with sliding sector is designed to transfer the system state from the outside to the inside of the sliding sector in a finite time and enable the system state stay inside the sliding sector, and the resulted VS control system is quadratically stable. The simulation results are its effectiveness.