석면함유 슬레이트 지붕 물받이 퇴적물 중 석면 섬유 함유율

임지현,한솔민,김현석,신유민,박시은,허정윤,김민영,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

This study attempted to determine the degree of asbestos release from the aging slate roof by comparing the asbestos content in the slate roof rain gutter with a colored steel plate (tin plate) over the slate roof. Four slate roof houses located in Haengmok-ri, Asan-si, Chungcheongnam-do, and one house constructed with a colored steel plate on the slate roof were selected to collect the sediment of the roof rain gutter. The asbestos fiber content was calculated by a point counting method using a polarization microscope after pretreatment with conversion treatment and hydrochloric acid treatment. The average asbestos content of the four slate roof rain gutter were 1.89%. However, asbestos was not detected in the Slate covering roof rain gutter, which were constructed on the slate roof. Asbestos fiber content was the highest at 2.89% in the slate roof rain gutter installed in 1976, followed by 2.44% in 1953. From the above results, it is necessary to minimize secondary damage as asbestos fibers released from slate roof houses to the surrounding atmosphere or leaked from slate roofs as rainwater may cause soil pollution and seriously affect residents' health. Although covering with colored steel plates (tin plates) has been shown to prevent the leakage of asbestos fibers to some extent, it is believed that a policy alternative to remove the slate roof as soon as possible is needed to solve the fundamental problem.

妊娠 第9 個月에 倂發한 Hirschsprung's Disease의 1例

申鉉卓,張潤錫,申旻雨,朴吉秀 大韓産婦人科學會 1963 大韓産婦人科學會雜誌 Vol.6 No.6

광주광역시 치매의 유병률과 위험인자의 도시-농촌 지역 비교

신일선,김재민,윤진상,김석재,양수진,김웅장,이승현,강순아,곽지영,이형영 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

연구목적 : 본 연구의 목적은 광주광역시의 도시 및 농촌 지역에 거주하는 노인에서 치매의 유병률과 위험인자를 조사하고자 하였다. 부가적으로 이 두 지역간에 치매의 유병률과 위험인자를 비교하고자 하였다. 방 법 : 광주광역시의 전형적인 도시와 농촌지역의 65세 이상의 노인(N=1,598)을 대상으로, 2단계의 역학연구를 수행하였다. 1차 선별 단계에서는 38명의 훈련된 연구보조원이 대상노인을 면담하여, 사회인구학적 특징을 조사하고 한국판 간이정신상태검사(Korean version of Mini-Mental State Examination ; MMSE-K)로 평가하였다. 2차 임상 진단 단계에서는 1차 단계에서 MMSE-K 점수가 24점 이하인 노인(N=431)을 대상으로, 전문연구팀의 임상적 평가를 통해 치매를 진단하고 원인질환별로 알쯔하이머병(Alzheimer's disease ; AD), 혈관성 치매(vascular dementia ; VaD) 및 기타 치매로 분류하였다. 대상노인에서 치매의 유병률을 측정한 후, 광주광역시 전체 노인의 연령보정 유병률을 산출하였다. 전체 대상에서 AD의 위험인자를 조사한 후, 도시와 농촌군으로 나누어 분석을 다시 시행하였다. 결 과 : 1차 및 2차 단계의 참가율은 각각 71.0%(N=1,134) 및 83.2%(N=410) 였다. 연구 참여 노인(N=1,134)에서 전체 치매, AD 및 VaD의 유병률은 최소 각각 9.7%, 5.2%, 1.8%였다. 광주광역시 전체 노인의 연령 보정 유병률은 각각 10.7%, 5.7%, 1.9%인 것으로 산출되었다. AD의 독립 위험인자는 고령, 여성, 무학이었다. 도시와 농촌에 따른 유병률의 차이는 파악되지 않았다. 그러나 AD의 위험인자는 지역에 따라 차이가 있었다. 도시 노인에게는 무학만이, 농촌 노인에게는 고령과 여성인 경우가 독립 위험인자였다. 결 론 : 광주광역시 노인에서 치매의 유병률은 높았고, 이는 국내 다른 지역에서 수행된 선행연구 결과와 유사하였다. 알쯔하이머형 치매의 위험인자는 도시와 농촌에 따라 다른 결과를 보였다. 본 연구 결과는 한국에서의 치매의 실태를 반영하며, 치매의 적절한 관리와 예방을 위해서는 지역성 특성이 고려되어야 함을 시사한다. Objectives : The purpose of this study was to investigate the prevalence rate and risk factors of dementia in an urban and a rural sample of older persons in the metropolitan Kwangju area, Republic of Korea. In addition, the prevalence rate and risk factors of dementia between the two samples were compared. Methods : A two-phase epidemiological study of residents aged 65 or over(N=1,598) was conducted in a highly developed, urban and a non-contiguous, poorly developed, rural area of metropolitan Kwangju. In the first(screening) phase, 38 trained research assistants collectively peformed in-home interviews for all participants. Detailed sociodemographic characteristics were gathered and the Korean version of Mini-Mental State Examination (MMSE-K) was administered. In the second (diagnosing) phase, diagnosis of dementia was established for those scoring 24 or less on the MMSE-K in the screening phase(N=431), and etiological types of dementia were classified to Alzheimer's disease(AD), vascular dementia(VaD) or miscellanous type by two teams of experts. Prevalence rate of dementia was determined in the participants, and age-standardized prevalence rate adjusted by age distribution in metropolitan Kwangju was estimated. For AD, the risk factors were investigated in all participants, and analyses were repeated for the urban and rural samples separately. Results : The participating rates in the first and second phases were 71.0%(N=1,134) and 83.2%(N=410), respectively. In the participants, the prevalence rates of dementia(all types), AD and VaD were 9.7%, 5.2% and 1.8%, respectively. The age-standardized prevalence rates were 10.7%, 5.7% and 1.9%, respectively. Aging, female gender and no education(complete lack of formal education) were identified as independent risk factors for AD. No difference between the urban and rural samples was observed in the prevalence rates of dementia(all types), AD and YaD. However, risk factors for AD differed between these areas. In the urban sample, no education was the only significant factor ; whereas, aging and female gender were identified as risk factors in the rural sample. Conclusion : A high prevalence rate of dementia was observed among old persons in metropolitan Kwangju, consistent with previous studies conducted in other Korean areas. The risk factor profi1es for AD differed between urban and rural settings. The results of this study reflect the current status of dementia in Korea and suggests that appropriate management and prevention strategies for dementia should be tailored toward the geographic settings.

편도체중심핵내 요힘빈과 날록손의미세주입이 신기성으로 유발된 통각감소에 미치는 효과

신맹식,조소현,김기석,김현택 한국심리학회 한국심리학회지 생물 및 생리 Vol.5 No.1

선행연구에서 동물이 새로운 환경에 노출되면 날록손에 역전되지 않는 통각감소 현상이 발생하며, 이러한 신기성으로 유발된 통각감소(novelty-induced hypoalgesia)는 세로토닌(serotonin: 5-HT)이나 노어피네프린(norepinephrine: NE)등의 모노아민계에 의해서 매개된다. 본연구에서는 정서/인지적 반응과 항유해적반응을 매개하는 하나의 신경구조물로 알려져 있는 편도체중심핵이 이러한 통각감소를 전달하는 데에 책임있는 영역인지, 그리고 NE의 작용에 아편계가 관여하는지를 알아보고자 하였다. 본실험에서는, 먼저 모든 쥐에게 양측 편도체중심핵을 표적으로 안내관을 심는 시술을 실시했다. 1주일 후 이들 쥐를 크게 노출집단과 비노출집단의 2 집단으로 나눈 후 노출집단만 23℃의 열판에서 매일 5분씩 7일간을 노출시켰다. 8일째에 각 집단을 다시 요힘빈집단과 생리식염수집단(요힘빈-노출집단, 요힘빈-빈노출집단, 생리식염수-노출집단 및 생리식염수-비노출집단)으로 분류한 다음 편도체중심핵의 양측에 해당의 각 약물을 미세주입하고 모든 동물을 49℃의 열판에 노출시켜서 뒷발바닥핥기 잠재기를 측정하였다. 각 동물을 열판장치에서 꺼내자마자 동일한 부위에 다시 날록손을 주입하고 앞에서와 동일하게 잠재기를 측정하였다. 실험결과, 열판기구라는 신기성환경에 의해서 통각감소가 유발되었음은 물론, 알파-2 NE 수용기 길항제인 요힘빈에 의해서는 비노출조건에서만 통각감소가 증가하였으며, 날록손의 경우는 비노출조건의 요힘빈집단에서만 통각감소가 감소하였다. 이들의 결과는 동물이 신기성환경에 접하면 공포와 함께 통각이 감소한다는 사실을 알려줄 뿐만 아니라, 편도체중심핵내의 NE가 이러한 효과를 매개 및 상승시킴을 의미한다. 그리고, 편도체중심핵에서 비노출조건의 요힘빈하에서만 아편계가 관여한다는 사실은 신기성환경으로 유발된 통각감소에 아편계가 단독으로 개입할 가능성은 미소하며 이런 종류의 통각감소에서 아편계보다는 NE계의 역할이 큼을 시사한다. Previous studies have reported that a novel environment renders animals hypoalgesic and this novelty-induced hypoalgesia(NIHA) is not reversed by naloxone-pretreatment; in fact, the NIHA seems to be mediated through the monoaminergic system such as serotoninergic- and noradrenergic substrate, according to the studies on the effects of i.p. injection of those receptor ligands on the NIHA. The present study is conducted to investigate not only whether the central amygdaloid nucleus(ACe), which is known as mediating anti-nociceptive response as well as emotional/cognitive ones including fear/anxiety response, is responsible for the NE-mediated NIHA, but also whether the opiate system modulates this kind of NE mediation. In the present experiment, all rats were first given bilateral cannulae-implantations into the ACe. 7 days later, after these rats were randomly assigned into two groups named 'exposure group(EXP)' and 'non-exposure group(NON)', only the EXP started to be exposed to the non-functional floor of the Hot-Plate Apparatus (at the temperature of 23℃) 5 minutes every day for 7 consecutive days. On the 8th day, after being divided into two subgroups such as yohimbine group and saline group and being supplied with bilaterally-microinjected yohimbine or saline equivalent to its condition into the ACe, each group received a hot-plate(49℃) test. The latency to lick a hind-paw was manually recorded. As soon as picked out of the Apparatus all the rats were re-provided with naloxone, one of opiate receptor antagonists, and were re-tested under the same conditions mentioned. The result is that the novelty rats produced more hypoalgesia than the adapted rats in the hindpaw-licking latency, and that the bilateral micro-injection of yohimbine, an α(2^-)NE receptor antagonist increaing NE release in the brain-neuron synaptic cleft by blocking the presynaptic autoreceptors, potentiated the hypoalgesia, only in the novelty rats; which indicates that the novelty-induced hypoalgesia appears to be carried through the NE substrate and that the ACe is the chief forebrain site conducting the NE-potentiated novety-induced hypoalgesia. As far as the effect of naloxone injection under the influence of the preinjected yohimbine and saline is concerned, the hypoalgesia was reduced only under the condition of novelty yohimbine, neither under that of novelty saline nor under that of non-novelty yohimbine and saline; which implicates the opiate substrast may participate in the hypoalgesia necessarily as the NE-substrate-dependant pattern rather than by itself. Thus, the NE system may play more important role than opiate system in mediating the novelty-induced hypoalgesia.

조직의 환경통제모형에 의한 산업재해의 구조적 발생에 관한 사례 연구

申炳玹,姜錫宰 홍익대학교 경영연구소 1989 경영연구 Vol.13 No.-

장애인복지시설의 수요자 중심 서비스를 위한 연구 : 사례관리(case management)를 중심으로 Focused on the Case Management

신현석 대구대학교 사회복지연구소 2003 社會福祉硏究 Vol.24 No.-

이 논문의 목적은 사례관리에 대한 체계적인 고찰을 통하여 우리나라 장애인복지시설에서 수요자 중심의 사례관리 서비스를 보다 효과적으로 제공하기 위한 대안들을 제시해 보고자 하는 것이다. 이 연구는 다음과 같은 방안을 제공하고자 한다 먼저 시설 내적 측면에서, 첫째,장애인복진시설에서 사례관리자에 대한 역할분담이 이루어져야 한다. 둘째. 수요자중심의 양질의 서비스가 제공되어야 한다. 셋째, 지역사회자원의 정보에 대한 체계적인 관리가 이루어져야 한다. 넷째, 장애인들의 강점 및 능력에 대한 체계적인 관리가 이루어져야 한다. 다섯째, 장애인들에 대한 권리옹호기능을 수행해야 한다. 또한 시설 외적 측면에서, 지역사회의 장애인복지서비스 인프라가 구축되어야 한다 둘째, 사례관리에 패한 전문적인 교육이 이루어져야 한다. 셋째, 사례관리에 대한 제도적인 규정이 이루어져야 한다. 넷째, 장애인자립생활센터의 공식적인 설치와 지원이 필요하다. The purpose of this study is to make alternatives to provide the disabled with case management services effectively in welfare facilities for the disabled. Studying the case management systematically. The results suggest the necessity of the followings. As regard to the internal aspects of the facilities, firstly, it should be alloted case manager' roles in the welfare facility for the disabled. Secondly, it should be provided with high qualify of services which are centered to clients. Thirdly, the case manager should manage information on resources in the community. Fourth, the case manager should manage the strengths and abilities of the disabled systematically. Finally, advocacy for the disabled should be accomplished in the facilities. As regard to the external aspects of the facilities, firstly, the infrastructure of services for the disabled should be established in the community. Secondly, the professional education about the case management should be given to students. Thirdly, clear statements of case management in a system should be completed. Finally. centers for independent living should be established for the disabled in this country.

내동정맥루술후의 수지운동이 동정맥루의 혈류와 개존에 미치는 영향

신현석,조원현,이성문,우성구,김현철 大韓脈管外科學會 1995 大韓脈管外科學會誌 Vol.11 No.1

지역아동센터 이용만족도에 영향을 미치는 요인 : 광주광역시 북구 지역을 중심으로

신웅철, 좌현숙 호남대학교 대학원 2014 호남대학교 대학원 논문집 Vol.9 No.-

This study is aimed to prepare for policy alternatives so as to improve further user satisfaction of community child care center along with supplying effective services in managing the center by analyzing impacted factors influencing user satisfaction of children user the centers. For achieving this research purposes, the study carried out questionnaires on the user satisfaction at community child care centers after selecting 13 centers located in the Buk-gu of Gwangju Metropolitan City. The results of this study are the following things. First, as long as using hour per day is, high satisfaction degrees are appeared on the operation program. Second, also children’s satisfaction of the environment and sanitation appeared to have great influence on user satisfaction. Third, satisfaction of relations with teachers are highest among all factors influencing to user satisfactions. Fourth, satisfaction degrees are observed differently according to friend relations. Therefore, it should place emphasis on developing various and children’s preference programs in order to improve user satisfaction of community child care center, moreover, this study suggests that safe and pleasant environment development, regular and continuous teacher education and improvement of relations between children using community child care centers is important. Keywords : Customer satisfaction, Community childcare center

사인에 의한 즉시형 과민반응의 억제 효과

신태용,염정열,김원,김현미,박해정,장진이,조성룡,채병숙 우석대학교 생명과학연구소 1998 생명과학연구소 논문집 Vol.2 No.-

We investigated the effect of aqueous extract of Ammomum xanthioides(AXAE) on immediate hypersensitivity. AXAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. AXAE inhibited serum histamine levels induced by compound 48/80 in mice. Moreover, AXAE dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80. These results indicate that the AXAE may be benificial in the regulation of immediate type allergic reaction.

연구개의 이소성 뇌조직 - 1예 보고-

최현주,이연수,김영신,이교영,강창석,심상인 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.11